Orthostatic myoclonus (OM) is a clinical phenomenon in which myoclonus of the lower limbs appears or becomes worse upon standing.(1) OM usually affects patients older than 65 years and may be a frequent cause of unsteadiness upon standing in the elderly.(2) Although the underlying etiology remains unclear, OM has predominantly been described in association with neurodegenerative diseases.(1) We describe a patient with OM in association with antibodies against contactin-associated protein-2 (Caspr2) whose symptoms markedly improved with immunotherapy.
Orthostatic myoclonus associated with Caspr2 antibodies
Erro, Roberto;
2016-01-01
Abstract
Orthostatic myoclonus (OM) is a clinical phenomenon in which myoclonus of the lower limbs appears or becomes worse upon standing.(1) OM usually affects patients older than 65 years and may be a frequent cause of unsteadiness upon standing in the elderly.(2) Although the underlying etiology remains unclear, OM has predominantly been described in association with neurodegenerative diseases.(1) We describe a patient with OM in association with antibodies against contactin-associated protein-2 (Caspr2) whose symptoms markedly improved with immunotherapy.File in questo prodotto:
Non ci sono file associati a questo prodotto.
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
