Supercritical phase inversion was used to prepare new polymeric membranes, based on cellulose acetate and Laponite®, for tissue engineering applications. These composite membranes were characterized by a porous structure (porosity around 85%) with an average pore size ranging from about 9 to 13 μm depending on the initial weight ratio cellulose acetate/Laponite. This ratio also controlled thermal and mechanical properties of these membranes: Laponite modified membrane decomposition step and increased the membrane elasticity modulus up to 4 MPa while decreasing the percentage elongation at break from 240% to 180%. Laponite also increased material cells adhesion: thanks to its homogeneous inclusion into the membranes, a remarkable cells adhesion of around 80%, six times higher than the original material, was obtained.
Preparation and characterization of cellulose acetate-Laponite® composite membranes produced by supercritical phase inversion
Cardea S.;Baldino L.
;Reverchon E.
2020
Abstract
Supercritical phase inversion was used to prepare new polymeric membranes, based on cellulose acetate and Laponite®, for tissue engineering applications. These composite membranes were characterized by a porous structure (porosity around 85%) with an average pore size ranging from about 9 to 13 μm depending on the initial weight ratio cellulose acetate/Laponite. This ratio also controlled thermal and mechanical properties of these membranes: Laponite modified membrane decomposition step and increased the membrane elasticity modulus up to 4 MPa while decreasing the percentage elongation at break from 240% to 180%. Laponite also increased material cells adhesion: thanks to its homogeneous inclusion into the membranes, a remarkable cells adhesion of around 80%, six times higher than the original material, was obtained.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
