: From December 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has spread rapidly, leading to a global pandemic. Little is known about possible relationships between SARS-CoV-2 and other viruses in the respiratory system affecting patient prognosis and outcomes. This study aims to characterize respiratory virome profiles in association with SARS-CoV-2 infection and disease severity, through the analysis in 89 nasopharyngeal swabs collected in a patient's cohort from the Campania region (Southern Italy). Results show coinfections with viral species belonging to Coronaviridae, Retroviridae, Herpesviridae, Poxviridae, Pneumoviridae, Pandoraviridae, and Anelloviridae families and only 2% of the cases (2/89) identified respiratory viruses.

Nasopharyngeal virome analysis of COVID-19 patients during three different waves in Campania region of Italy

Melone, Viola
Investigation
;
Fromentier, Aurore
Investigation
;
Rocco, Teresa
Investigation
;
D'Agostino, Ylenia
Investigation
;
Lamberti, Jessica
Investigation
;
Alexandrova, Elena
Investigation
;
Pecoraro, Giovanni
Investigation
;
Pagliano, Pasquale
Supervision
;
Weisz, Alessandro
Supervision
;
Giurato, Giorgio
Conceptualization
;
Galdiero, Massimiliano
Supervision
;
Rizzo, Francesca
Conceptualization
;
Franci, Gianluigi
Supervision
2022

Abstract

: From December 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has spread rapidly, leading to a global pandemic. Little is known about possible relationships between SARS-CoV-2 and other viruses in the respiratory system affecting patient prognosis and outcomes. This study aims to characterize respiratory virome profiles in association with SARS-CoV-2 infection and disease severity, through the analysis in 89 nasopharyngeal swabs collected in a patient's cohort from the Campania region (Southern Italy). Results show coinfections with viral species belonging to Coronaviridae, Retroviridae, Herpesviridae, Poxviridae, Pneumoviridae, Pandoraviridae, and Anelloviridae families and only 2% of the cases (2/89) identified respiratory viruses.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11386/4775961
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