: From December 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has spread rapidly, leading to a global pandemic. Little is known about possible relationships between SARS-CoV-2 and other viruses in the respiratory system affecting patient prognosis and outcomes. This study aims to characterize respiratory virome profiles in association with SARS-CoV-2 infection and disease severity, through the analysis in 89 nasopharyngeal swabs collected in a patient's cohort from the Campania region (Southern Italy). Results show coinfections with viral species belonging to Coronaviridae, Retroviridae, Herpesviridae, Poxviridae, Pneumoviridae, Pandoraviridae, and Anelloviridae families and only 2% of the cases (2/89) identified respiratory viruses.
Nasopharyngeal virome analysis of COVID-19 patients during three different waves in Campania region of Italy
Ferravante, CarloInvestigation
;Melone, ViolaInvestigation
;Fromentier, AuroreInvestigation
;Rocco, TeresaInvestigation
;D'Agostino, YleniaInvestigation
;Lamberti, JessicaInvestigation
;Alexandrova, ElenaInvestigation
;Pecoraro, GiovanniInvestigation
;Pagliano, PasqualeSupervision
;Weisz, AlessandroSupervision
;Giurato, GiorgioConceptualization
;Galdiero, MassimilianoSupervision
;Rizzo, Francesca
Conceptualization
;Franci, Gianluigi
Supervision
2022-01-01
Abstract
: From December 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has spread rapidly, leading to a global pandemic. Little is known about possible relationships between SARS-CoV-2 and other viruses in the respiratory system affecting patient prognosis and outcomes. This study aims to characterize respiratory virome profiles in association with SARS-CoV-2 infection and disease severity, through the analysis in 89 nasopharyngeal swabs collected in a patient's cohort from the Campania region (Southern Italy). Results show coinfections with viral species belonging to Coronaviridae, Retroviridae, Herpesviridae, Poxviridae, Pneumoviridae, Pandoraviridae, and Anelloviridae families and only 2% of the cases (2/89) identified respiratory viruses.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.