Abstract Background Coronary CT (CCT) is one of the most used noninvasive imaging for the detection of coronary artery disease (CAD) in the US, especially in patients with intermediate CAD risk. European Society of Cardiology also recommends risk stratifications using coronary CT angiography in patients with suspected CAD (level IB). Purpose the purpose of the study was to evaluate in a population that underwent CCT screening, how many had significant coronary lesions and which cardiovascular (CV) risk factors were most involved. Methods 228 patients (37% female, 63,34±9.9 years) with no previous coronary events and 64,5% with no coronary symptoms (angor, dyspnea), were enrolled. All patients underwent a cardiological evaluation for CV risk factors (age, sex, hypertension, early familiarity for CAD, dyslipidemia, smoke, obesity, diabetes, chronic kidney failure, vascular atherosclerosis) and a CCT (Ca scoring and CT angiography), performed by a 128-slices system and analyzed by a single operator with over 3 years of experience. CCT was considered positive if CAD-RADS was ≥ 4A. Results 60 patients (26,3%) had a positive CCT and were hospitalized for coronary angiography. The CCT positivity correlated significantly with the sex (p<0.001), familiarity (p<0.001), hypertension (p= 0.006) and Ca Score (p<0.001), but did not significantly correlate with the other risk factors (dyslipidemia, smoke, age, obesity, diabetes, chronic kidney failure, vascular atherosclerosis) or symptoms (Table.1). Conclusions family history and sex, together with hypertension, seem to be the factors that most determine the presence of ischemic heart disease, more than the other common risk factors. The possibility of performing CCT in all patients with early family history could be considered to effectively prevent the onset of coronary events. Table.1
335 CORONARY CT SCREENING: A PRIMARY ROLE IN CORONARY EVENTS PREVENTION
Carmine Izzo
2022-01-01
Abstract
Abstract Background Coronary CT (CCT) is one of the most used noninvasive imaging for the detection of coronary artery disease (CAD) in the US, especially in patients with intermediate CAD risk. European Society of Cardiology also recommends risk stratifications using coronary CT angiography in patients with suspected CAD (level IB). Purpose the purpose of the study was to evaluate in a population that underwent CCT screening, how many had significant coronary lesions and which cardiovascular (CV) risk factors were most involved. Methods 228 patients (37% female, 63,34±9.9 years) with no previous coronary events and 64,5% with no coronary symptoms (angor, dyspnea), were enrolled. All patients underwent a cardiological evaluation for CV risk factors (age, sex, hypertension, early familiarity for CAD, dyslipidemia, smoke, obesity, diabetes, chronic kidney failure, vascular atherosclerosis) and a CCT (Ca scoring and CT angiography), performed by a 128-slices system and analyzed by a single operator with over 3 years of experience. CCT was considered positive if CAD-RADS was ≥ 4A. Results 60 patients (26,3%) had a positive CCT and were hospitalized for coronary angiography. The CCT positivity correlated significantly with the sex (p<0.001), familiarity (p<0.001), hypertension (p= 0.006) and Ca Score (p<0.001), but did not significantly correlate with the other risk factors (dyslipidemia, smoke, age, obesity, diabetes, chronic kidney failure, vascular atherosclerosis) or symptoms (Table.1). Conclusions family history and sex, together with hypertension, seem to be the factors that most determine the presence of ischemic heart disease, more than the other common risk factors. The possibility of performing CCT in all patients with early family history could be considered to effectively prevent the onset of coronary events. Table.1I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
