SBARDELLA, Gianluca
SBARDELLA, Gianluca
Dipartimento di Farmacia/DIFARMA
3,4-Dihydro-2-alkoxy-6-benzyl-oxopyrimidines [DABOs]: Development of a potent class of non-nucleoside reverse transcriptase inhibitors
2001-01-01 M., Elena Marongiu; Alessandra, Pani; Chiara, Musiu; Paolo La, Colla; Antonello, Mai; Sbardella, Gianluca; Silvio, Massa; Marino, Artico
3-(1H-Pyrrol-1-yl)-2-oxazolidinones as Reversible, Highly Potent, and Selective Inhibitors of Monoamine Oxidase Type A
2002-01-01 Mai, Antonello; Artico, Marino; Esposito, Monica; Sbardella, Gianluca; Massa, Silvio; Befani, Olivia; Turini, Paola; Giovannini, Valentina; Mondovì, Bruno
3-(1H-Pyrrol-2- and -3-yl)-2-oxazolidinones as Novel Monoamine Oxidase Type A Inhibitors
2002-01-01 Sbardella, Gianluca; A., Mai; M., Esposito; M., Artico; S., Massa; O., Befani; V., Giovannini; B., Mondovì
3-(1H-Pyrrol-2-yl)-2-oxazolidinones as Novel Monoamine Oxidase Type A Inhibitors
2005-01-01 Mai, Antonello; Artico, Marino; Valente, Sergio; Sbardella, Gianluca; Turini, Paola; Befani, Olivia; Dalla Vedova, Laura; Agostinelli, Enzo
3-(4-Aroyl-1H-pyrrol-2-yl)-N-hydroxy-2-propenamides, a New Class of Synthetic Histone Deacetylase Inhibitors
2001-01-01 Silvio, Massa; Antonello, Mai; Sbardella, Gianluca; Monica, Esposito; Rino, Ragno; Peter, Loidl; Gerald, Brosch
5-Alkyl-2-(alkylthio)-6-(2,6-dihalophenylmethyl)-3,4-dihydropyrimidin-4( 3H)-ones: novel potent and selective dihydro-alkoxy-benzyl-oxopyrimidine derivatives.
1999-01-01 Mai, Antonello; Artico, Marino; Sbardella, Gianluca; Massa, Silvio; Novellino, Ettore; Greco, Giovanni; Loi, Anna Giulia; Tramontano, Enzo; Marongiu, Maria Elena; La Colla, Paolo
5-Alkyl-2-alkylamino-6-(2,6-difluorophenylalkyl)-3,4-dihydro-5-alkylpyrimidin-4(3H)-ones, a New Series of Potent, Broad-Spectrum Non-Nucleoside Reverse Transcriptase Inhibitors Belonging to the DABO family
2005-01-01 Mai, Antonello; Artico, Marino; Ragno, Rino; Sbardella, Gianluca; Massa, Silvio; Musiu, Claudia; Mura, Massimo; Marturana, Flavia; Cadeddu, Alessandra; Maga, Giovanni; La Colla, Paolo
6-[1-(2,6-Difluorophenyl)ethyl]pyrimidinones Antagonize Cell Proliferation and Induce Cell Differentiation by Inhibiting (a Non Telomeric) Endogenous Reverse Transcriptase
2005-01-01 Bartolini, S; Mai, A; Artico, M; Paesano, N; Rotili, D; Spadafora, C; Sbardella, Gianluca
6-Alkylthio-4-[1-(2,6-difluorophenyl)alkyl]-1H-[1,3,5]triazin-2-ones (ADATs): Novel Regulators of Cell Differentiation and Proliferation
2006-01-01 Sbardella, Gianluca; Bartolini, S; Castellano, Sabrina; Artico, M; Paesano, N; Rotili, D; Spadafora, C; Mai, A.
A continuous-flow synthesis of 1,4-benzodiazepin-5-ones, privileged scaffolds for drug discovery
2015-01-01 Viviano, Monica; Milite, Ciro; Rescigno, Donatella; Castellano, Sabrina; Sbardella, Gianluca
A continuous-flow synthesis of 1,4-benzodiazepin-5-ones, privileged scaffolds for drug discovery.
2015-01-01 Rescigno, Donatella; Viviano, Monica; Milite, Ciro; Sbardella, Gianluca; Castellano, Sabrina
A new facile and expeditious synthesis of N-hydroxy-N'-phenyloctanediamide, a potent inducer of terminal cytodifferentiation
2001-01-01 Mai, A; Esposito, M; Sbardella, Gianluca; Massa, S.
A novel cell-permeable, selective and noncompetitive inhibitor of KAT3 histone acetyltransferases from a combined molecular pruning/classical isosterism approach
2015-01-01 Milite, Ciro; Feoli, Alessandra; Kazuki, Sasaki; Valeria, La Pietra; Balzano, AMODIO LUCA; Luciana, Marinelli; Antonello, Mai; Ettore, Novellino; Castellano, Sabrina; Tosco, Alessandra; Sbardella, Gianluca
A novel Gcn5p inhibitor represses cell growth, gene transcription and histone acetylation in budding yeast
2005-01-01 Ornaghi, Prisca; Rotili, Dante; Sbardella, Gianluca; Mai, Antonello; Filetici, Patrizia
A practical, green and selective approach toward the synthesis of pharmacologically important quinone-containing heterocyclic systems using alumina-catalyzed Michael addition reaction.
2008-01-01 Castellano, Sabrina; Bertamino, Alessia; Gomez Monterrey, Isabel; Santoriello, Marisabella; Grieco, Paolo; Campiglia, Pietro; Sbardella, Gianluca; Novellino, Ettore
A regioselective approach toward the synthesis of pharmacologically important quinone-containing heterocyclic systems
2009-01-01 Castellano, Sabrina; Santoriello, Marisabella; Campiglia, Pietro; Cardillo, Giovanna; Bertamino, Alessia; Gomez Monterrey, Isabel; Novellino, Ettore; Sbardella, Gianluca
A simplified synthesis of ethyl 5-chloro-6-fluoro-1H-indole-2-carboxylate and ethyl 5-chloro-4-fluoro-1H-indole-2-carboxylate
2002-01-01 Silvestri, Romano; De Martino, Gabriella; Sbardella, Gianluca
A TR-FRET-Based Functional Assay for Screening Activators of CARM1
2013-01-01 Hao, Zeng; Jiacai, Wu; Mark T., Bedford; Sbardella, Gianluca; F., Michael Hoffmann; Kun, Bi; Wei, Xu
A transcriptional coregulator, SPIN-DOC, attenuates the coactivator activity of Spindlin1
2017-01-01 Bae, Narkhyun; Gao, Min; Li, Xu; Premkumar, Tolkappiyan; Sbardella, Gianluca; Chen, Junjie; Bedford, Mark T.
A “library-on-library” screening approach to identify small-molecule ligands of methyl-lysine reader proteins
2016-01-01 Sbardella, Gianluca
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| 3,4-Dihydro-2-alkoxy-6-benzyl-oxopyrimidines [DABOs]: Development of a potent class of non-nucleoside reverse transcriptase inhibitors | 1-gen-2001 | M., Elena Marongiu; Alessandra, Pani; Chiara, Musiu; Paolo La, Colla; Antonello, Mai; Sbardella, Gianluca; Silvio, Massa; Marino, Artico | |
| 3-(1H-Pyrrol-1-yl)-2-oxazolidinones as Reversible, Highly Potent, and Selective Inhibitors of Monoamine Oxidase Type A | 1-gen-2002 | Mai, Antonello; Artico, Marino; Esposito, Monica; Sbardella, Gianluca; Massa, Silvio; Befani, Olivia; Turini, Paola; Giovannini, Valentina; Mondovì, Bruno | |
| 3-(1H-Pyrrol-2- and -3-yl)-2-oxazolidinones as Novel Monoamine Oxidase Type A Inhibitors | 1-gen-2002 | Sbardella, Gianluca; A., Mai; M., Esposito; M., Artico; S., Massa; O., Befani; V., Giovannini; B., Mondovì | |
| 3-(1H-Pyrrol-2-yl)-2-oxazolidinones as Novel Monoamine Oxidase Type A Inhibitors | 1-gen-2005 | Mai, Antonello; Artico, Marino; Valente, Sergio; Sbardella, Gianluca; Turini, Paola; Befani, Olivia; Dalla Vedova, Laura; Agostinelli, Enzo | |
| 3-(4-Aroyl-1H-pyrrol-2-yl)-N-hydroxy-2-propenamides, a New Class of Synthetic Histone Deacetylase Inhibitors | 1-gen-2001 | Silvio, Massa; Antonello, Mai; Sbardella, Gianluca; Monica, Esposito; Rino, Ragno; Peter, Loidl; Gerald, Brosch | |
| 5-Alkyl-2-(alkylthio)-6-(2,6-dihalophenylmethyl)-3,4-dihydropyrimidin-4( 3H)-ones: novel potent and selective dihydro-alkoxy-benzyl-oxopyrimidine derivatives. | 1-gen-1999 | Mai, Antonello; Artico, Marino; Sbardella, Gianluca; Massa, Silvio; Novellino, Ettore; Greco, Giovanni; Loi, Anna Giulia; Tramontano, Enzo; Marongiu, Maria Elena; La Colla, Paolo | |
| 5-Alkyl-2-alkylamino-6-(2,6-difluorophenylalkyl)-3,4-dihydro-5-alkylpyrimidin-4(3H)-ones, a New Series of Potent, Broad-Spectrum Non-Nucleoside Reverse Transcriptase Inhibitors Belonging to the DABO family | 1-gen-2005 | Mai, Antonello; Artico, Marino; Ragno, Rino; Sbardella, Gianluca; Massa, Silvio; Musiu, Claudia; Mura, Massimo; Marturana, Flavia; Cadeddu, Alessandra; Maga, Giovanni; La Colla, Paolo | |
| 6-[1-(2,6-Difluorophenyl)ethyl]pyrimidinones Antagonize Cell Proliferation and Induce Cell Differentiation by Inhibiting (a Non Telomeric) Endogenous Reverse Transcriptase | 1-gen-2005 | Bartolini, S; Mai, A; Artico, M; Paesano, N; Rotili, D; Spadafora, C; Sbardella, Gianluca | |
| 6-Alkylthio-4-[1-(2,6-difluorophenyl)alkyl]-1H-[1,3,5]triazin-2-ones (ADATs): Novel Regulators of Cell Differentiation and Proliferation | 1-gen-2006 | Sbardella, Gianluca; Bartolini, S; Castellano, Sabrina; Artico, M; Paesano, N; Rotili, D; Spadafora, C; Mai, A. | |
| A continuous-flow synthesis of 1,4-benzodiazepin-5-ones, privileged scaffolds for drug discovery | 1-gen-2015 | Viviano, Monica; Milite, Ciro; Rescigno, Donatella; Castellano, Sabrina; Sbardella, Gianluca | |
| A continuous-flow synthesis of 1,4-benzodiazepin-5-ones, privileged scaffolds for drug discovery. | 1-gen-2015 | Rescigno, Donatella; Viviano, Monica; Milite, Ciro; Sbardella, Gianluca; Castellano, Sabrina | |
| A new facile and expeditious synthesis of N-hydroxy-N'-phenyloctanediamide, a potent inducer of terminal cytodifferentiation | 1-gen-2001 | Mai, A; Esposito, M; Sbardella, Gianluca; Massa, S. | |
| A novel cell-permeable, selective and noncompetitive inhibitor of KAT3 histone acetyltransferases from a combined molecular pruning/classical isosterism approach | 1-gen-2015 | Milite, Ciro; Feoli, Alessandra; Kazuki, Sasaki; Valeria, La Pietra; Balzano, AMODIO LUCA; Luciana, Marinelli; Antonello, Mai; Ettore, Novellino; Castellano, Sabrina; Tosco, Alessandra; Sbardella, Gianluca | |
| A novel Gcn5p inhibitor represses cell growth, gene transcription and histone acetylation in budding yeast | 1-gen-2005 | Ornaghi, Prisca; Rotili, Dante; Sbardella, Gianluca; Mai, Antonello; Filetici, Patrizia | |
| A practical, green and selective approach toward the synthesis of pharmacologically important quinone-containing heterocyclic systems using alumina-catalyzed Michael addition reaction. | 1-gen-2008 | Castellano, Sabrina; Bertamino, Alessia; Gomez Monterrey, Isabel; Santoriello, Marisabella; Grieco, Paolo; Campiglia, Pietro; Sbardella, Gianluca; Novellino, Ettore | |
| A regioselective approach toward the synthesis of pharmacologically important quinone-containing heterocyclic systems | 1-gen-2009 | Castellano, Sabrina; Santoriello, Marisabella; Campiglia, Pietro; Cardillo, Giovanna; Bertamino, Alessia; Gomez Monterrey, Isabel; Novellino, Ettore; Sbardella, Gianluca | |
| A simplified synthesis of ethyl 5-chloro-6-fluoro-1H-indole-2-carboxylate and ethyl 5-chloro-4-fluoro-1H-indole-2-carboxylate | 1-gen-2002 | Silvestri, Romano; De Martino, Gabriella; Sbardella, Gianluca | |
| A TR-FRET-Based Functional Assay for Screening Activators of CARM1 | 1-gen-2013 | Hao, Zeng; Jiacai, Wu; Mark T., Bedford; Sbardella, Gianluca; F., Michael Hoffmann; Kun, Bi; Wei, Xu | |
| A transcriptional coregulator, SPIN-DOC, attenuates the coactivator activity of Spindlin1 | 1-gen-2017 | Bae, Narkhyun; Gao, Min; Li, Xu; Premkumar, Tolkappiyan; Sbardella, Gianluca; Chen, Junjie; Bedford, Mark T. | |
| A “library-on-library” screening approach to identify small-molecule ligands of methyl-lysine reader proteins | 1-gen-2016 | Sbardella, Gianluca |