PEPE, Stefano
 Distribuzione geografica
Continente #
NA - Nord America 13.658
AS - Asia 7.307
EU - Europa 4.329
SA - Sud America 740
Continente sconosciuto - Info sul continente non disponibili 321
AF - Africa 120
OC - Oceania 15
Totale 26.490
Nazione #
US - Stati Uniti d'America 13.492
HK - Hong Kong 2.590
SG - Singapore 2.062
IT - Italia 1.637
CN - Cina 1.179
UA - Ucraina 769
VN - Vietnam 602
BR - Brasile 589
DE - Germania 465
RU - Federazione Russa 336
IE - Irlanda 272
FI - Finlandia 238
FR - Francia 218
KR - Corea 184
TR - Turchia 172
IN - India 126
GB - Regno Unito 98
SE - Svezia 96
BD - Bangladesh 91
CA - Canada 85
AR - Argentina 59
JP - Giappone 56
IQ - Iraq 46
AT - Austria 43
NL - Olanda 40
ID - Indonesia 37
MX - Messico 37
PK - Pakistan 32
EU - Europa 30
ES - Italia 26
ZA - Sudafrica 24
UZ - Uzbekistan 23
CZ - Repubblica Ceca 22
PL - Polonia 22
CO - Colombia 21
EC - Ecuador 21
MA - Marocco 19
JO - Giordania 18
TN - Tunisia 18
CL - Cile 14
IL - Israele 14
VE - Venezuela 14
CR - Costa Rica 12
DZ - Algeria 12
KE - Kenya 11
SA - Arabia Saudita 10
AU - Australia 9
MY - Malesia 8
PE - Perù 8
JM - Giamaica 7
PH - Filippine 7
PY - Paraguay 7
RO - Romania 7
AL - Albania 6
EG - Egitto 6
KG - Kirghizistan 6
AE - Emirati Arabi Uniti 5
AZ - Azerbaigian 5
BG - Bulgaria 5
CH - Svizzera 5
OM - Oman 5
XK - ???statistics.table.value.countryCode.XK??? 5
GT - Guatemala 4
NG - Nigeria 4
PA - Panama 4
TT - Trinidad e Tobago 4
BO - Bolivia 3
DO - Repubblica Dominicana 3
ET - Etiopia 3
GR - Grecia 3
LB - Libano 3
LT - Lituania 3
MD - Moldavia 3
NO - Norvegia 3
NP - Nepal 3
NZ - Nuova Zelanda 3
SN - Senegal 3
SY - Repubblica araba siriana 3
UY - Uruguay 3
AO - Angola 2
BF - Burkina Faso 2
BH - Bahrain 2
BS - Bahamas 2
DK - Danimarca 2
EE - Estonia 2
HN - Honduras 2
IR - Iran 2
KH - Cambogia 2
KZ - Kazakistan 2
MK - Macedonia 2
MN - Mongolia 2
PR - Porto Rico 2
PT - Portogallo 2
SC - Seychelles 2
TH - Thailandia 2
TW - Taiwan 2
ZM - Zambia 2
AG - Antigua e Barbuda 1
AM - Armenia 1
BA - Bosnia-Erzegovina 1
Totale 26.177
Città #
Ann Arbor 2.852
Hong Kong 2.585
Woodbridge 1.236
Singapore 1.167
Wilmington 1.082
Jacksonville 923
Houston 917
San Jose 901
Chandler 794
Princeton 663
Milan 631
Dallas 569
Ashburn 557
Beijing 370
Dong Ket 290
Dublin 268
Council Bluffs 211
Lauterbourg 183
Munich 176
Andover 172
The Dalles 168
Nanjing 150
Izmir 145
Boardman 125
Pellezzano 125
Rome 125
Naples 113
Ho Chi Minh City 111
Santa Clara 108
Mestre 107
Los Angeles 95
Moscow 87
New York 79
Hanoi 77
Düsseldorf 67
Fairfield 55
São Paulo 54
Memphis 50
Nanchang 50
Tokyo 50
Helsinki 47
Salerno 46
Shenyang 46
Hebei 44
Figino 41
Chicago 39
Changsha 38
Washington 38
Jiaxing 37
Orem 33
Pune 32
Turin 31
Brooklyn 30
Nuremberg 29
Columbus 28
Turku 28
Falls Church 26
Tianjin 26
Vienna 26
Frankfurt am Main 24
San Francisco 24
Montreal 23
Norwalk 23
Seattle 23
Tashkent 21
Brasília 20
London 20
Warsaw 20
Chennai 19
Denver 18
Amman 17
Amsterdam 17
Baghdad 17
Brno 17
Toronto 17
Venezia 17
Atlanta 16
Cambridge 16
Mexico City 16
Rio de Janeiro 16
Boston 15
Da Nang 15
Haiphong 15
Redwood City 15
Guangzhou 14
Shanghai 14
Biên Hòa 13
Fisciano 13
Mumbai 13
Paris 13
San Diego 13
Bologna 12
Manchester 12
Ottawa 12
Quito 12
Stockholm 12
Belo Horizonte 11
Buffalo 11
Phoenix 11
Poplar 11
Totale 19.811
Nome #
Epidermal growth factor receptor (EGFr) expression in non-small cell lung carcinomas correlates with metastatic involvement of hilar and mediastinal lymph nodes in the squamous subtype 608
Prior Anti-Angiogenic TKI-Based Treatment as Potential Predisposing Factor to Nivolumab-Mediated Recurrent Thyroid Disorder Adverse Events in mRCC Patients: A Case Series 539
Bispecific Antibodies: A Novel Approach for the Treatment of Solid Tumors 516
Differential sensitivity to non-MHC-restricted rIL-2 activated lymphocyte killing of human mammary epithelial MCF-10A cells overexpressing oncogenes or PKA subunits. 366
Abstract 3132: Single nucleotide polymorphisms (SNPs) in PD-L1 as predictive biomarkers for checkpoint inhibitor based-immunotherapy in caucasian patients with advanced NSCLC 334
Measurement of neovascularization is an independent prognosticator of survival in node-negative breast cancer patients with long-term follow-up 307
Synergistic antitumor activity of epidermal growth factor receptor tyrosine kinase inhibitor gefitinib and IFN-A in head and neck cancer cells in vitro and in vivo 300
The role of immunotherapy in solid tumors: report from the Campania Society of Oncology Immunotherapy (SCITO) meeting, Naples 2014. 295
Evaluation of Potential Predictive Biomarkers for Defining Brain Radiotherapy Efficacy in Non-Small Cell Lung Cancer Patients with Brain Metastases: A Case Report and a Narrative Review 256
Radioresistance in head and neck squamous cell carcinoma: Biological bases and therapeutic implications. 221
Overexpression of wild-type p53 ovverrides the mitogenic effect of the RIa subunit of protein kinase A in human breast cells. 204
rs822336 as a predictive biomarker for anti-PD-1/PD-L1 immunotherapy in advanced NSCLC: Unraveling molecular mechanisms 199
Additive effects of c-erbB-2, c-Ha-ras, and transforming growth factor-a genes on in vitro transformation of human mammary epithelial cells. 188
A genotyping/phenotyping approach with careful clinical monitoring to manage the fluoropyrimidines-based therapy: Clinical cases and systematic review of the literature 188
Nuclear DNA content-derived parameters correlated with heterogeneous expression of p53 and bcl-2 proteins in clear cell renal carcinomas. 186
A phase I-II trial of gefitinib (IRESSA) and radiotherapy in patients with locally advanced inoperable squamous cell carcinoma of the head and neck (SCCHN) 184
Phase I clinical study with 8-Chloro-cAMP and evaluation of immunological effects in cancer patients. 181
Adjuvant treatment of diabetic foot 180
5-Aza-2'-Deoxycitidine induces growth-inhibition and up-regulation of epidermal-growth factor receptor on human epithelial cancer-cells 180
ADDITION OF ERLOTINIB TO FLUROPYRIMIDINE-OXALIPLATIN-BASED CHEMOTHERAPY WITH OR WITHOUT BEVACIZUMAB: TWO SEQUENTIAL PHASE I TRIALS. 178
A phase II study of biweekly oxaliplatin plus infusional 5-fluorouracil and folinic acid (FLFOX-4) as first-line treatment of advanced gastric cancer patients. 174
Anti-sense oligonucleotides directed against EGF-related growth factors enhance anti-proliferative effect of conventional anti-tumor drugs in human colon-cancer cells. 166
8-Chloro-cAMP enhances the growth inhibitory effect of cytotoxic drugs in human colon cancer cells 164
Procoagulant and fibrinolytic activity of human ovarian carcinoma cells in culture. 164
Enhancement of antitumor activity of ionizing radiation by combined treatment with the selective EGFR-tyrosine kinase inhibitor ZD1839 (‘Iressa’) 163
Poly(ADPR)polymerase-1 signalling of the DNA damage induced by DNA topoisomerase I poison in D54p53wt and U251p53mut glioblastoma cell lines. 163
Regulation of the expression of Fc-epsilon-R in the human monocyte like cell line U937 by TPA and IgE. 162
Reversal of adriamycin resistance by recombinant alpha-interferon in multidrug-resistant human colon carcinoma LoVo-doxorubicin cells. 161
Activity and safety of pegylated liposomal doxorubicin, 5-fluorouracil and folinic acid in inoperable hepatocellular carcinoma: a phase II study. 160
A phase II study of biweekly oxaliplatin plus infusional 5-fluorouracil and folinic acid (FOLFOX-4) as first-line treatment of advanced gastric cancer patients. 158
8-Cl-cAMP in differentiation therapy: The reversal and suppression of malignancy targeting the intracellular transducing proteins of cAMP. 158
Adjuvant Treatment for Locally Advanced Rectal Cancer Patients After Preoperative Chemoradiotherapy: When, and for Whom? 157
TSH-regulated growth and cell cycle distribution of thyroid cells involve type I isozyme of cAMP-dependent protein kinase 156
Abstract 4017: Anti-tumor activity of a BRAF inhibitor and IFNα combination in BRAF mutant melanoma 156
Modulation of thymidilate synthase and p53 expression by HDAC inhibitor vorinostat resulted in synergistic antitumor effect in combination with 5FU or raltitrexed. 155
Recombinant IFN-alfa 2b treatment activates poly (ADPR) polymerase-1 (PARP-1) in KB cancer cells. 154
Retinoic acid induces neuronal differentiation of embryonal carcinoma cells by reducing proteasome-dependent proteolysis of the cyclin-dependent inhibitor p27. 154
Down-regulation of RI alpha subunit of cAMP-dependent protein kinase induces growth inhibition of human mammary epithelial cells transformed by c-Ha-ras and c-erbB-2 proto-oncogenes. 154
Tumori Eredo-Familiari 154
Antitumor activity of BRAF inhibitor and IFN×alpha; Combination in BRAF-mutant melanoma 154
NM23 gene expression correlates with cell growth rate and S-phase. 153
Synergistic anti-tumour effect of raltitrexed and 5-fluorouracil plus folinic acid combination in human cancer cells. 152
Expression of teratocarcinoma-derived growth factor-1 (TDGF-1) in testis germ cell tumors and its effects on growth and differentiation of embryonal carcinoma cell line NTERA2/D1. 150
Enhanced Expression of CD47 Is Associated With Off-Target Resistance to Tyrosine Kinase Inhibitor Gefitinib in NSCLC 150
A phase I/II trial of gefitinib and radiotherapy in patients with locally advanced inoperable squamous cell carcinoma of the head and neck. 148
Altre Neoplasie 148
A specific miRNA signature correlates with complete pathological response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer 148
DNA index of ovarian carcinomas from 56 different patients: in vivo, in vitro studies. 147
Analysis of Differential miRNA Expression in Primary Tumor and Stroma of Colorectal Cancer Patients 147
Farsi promotori di salute: “Safe Sun Coast” 144
Sequence-dependent, synergistic antiproliferative and proapoptotic effects of the combination of cytotoxic drugs and enzastaurin, a protein kinase C beta inhibitor, in non-small cell lung cancer cells. 143
rs10204525 binding to miR-4717-3p modulates PD-1 expression and predicts the development of immune-related adverse events in advanced cancer patients treated with anti-PD-1/PD-L1 therapy 142
Loss of thyrotropin regulation and trasforming growth factor beta-induced growth arrest in erbB-2 overexpressing rat thyroid cells. 142
The expression of proliferating cell nuclear antigen in paraffin sections of peripheral, node-negative non-small cell lung cancer. 142
Type-I isoform of PKA is involved in the control of cell proliferation and oncogene transformation of human mammary epithelial cells.Therapeutic implications 142
Non lymphomatous clonal B-Cell populations in enlarged lymph nodes in acquired immunodeficiency syndrome. 141
Critical role of both p27kip1 and p21cip1/waf1 in the antiproliferative effect of ZD1839 (‘Iressa’), an epidermal growth factor receptor tyrosine kinase inhibitor, in head and neck squamous carcinoma cells. 140
DNA-flow cytometry (ploidy and S-phase fraction) as prognostic factor in a retrospectine series of 515 primary breast cancer. 140
Predictive factors of response to neoadjuvant chemoradiotherapy in rectal cancer patirnts. 140
Oral antisense targeting protein kinase A type I causes antitumor and apoptotic effect in human cancer cells in vitro and in vivo and has cooperative activity in combination with antisense bcl-2. 140
TGFb inhibits rat thyroid cell proliferation without alterations in the expression of THS-induced cell cycle-related genes. Vol :pp , 139
A Specific miRNA Signature Correlates with Complete Pathological Response to Neoadjuvant Chemoradiotherapy in Locally Advanced Rectal Cancer. 139
Reduction of RIAlpha subunit of cAMP-dependent Protein-Kinase expression induces growth-inhibition of human mammary epithelial-cells transformed by TGF-Alha, C-HA-RAS, and C-ErbB2 genes. 138
Bevacizumab maintenance in metastatic colorectal cancer: How long?. 138
Abstract 3703: PDGFRα up-regulation mediated by Sonic Hedgehog Pathway activation leads to BRAF inhibitor resistance in melanoma cells with BRAF mutation 138
Synergistic anti-proliferative and pro-apoptotic activity of combined therapy with bortezomib, a proteasome inhibitor, with anti-epidermal growth factor receptor (EGFR) drugs in human cancer cells. 137
Neo-adjuvant treatment of rectal cancer with capecitabine and oxaliplatin in combination with radiotherapy: a phase II study. 137
Growth inhibition of tumor cells by epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 is associated with upregulation of p27 and p21 cyclin-dependent kinase inhibitors. 137
Cooperative inhibitory effect of novel mixed backbone oligonucleotide targeting Protein Kinase A in combination with docetaxel and anti-EGFR-Receptor antibody on human breast cancer cell growth. 136
Cell growth-inhibition and cell cycle perturbations induced by a new synthetic iminoquinone, 5H-pyridophenoxazin-5-one, in human breast carcinoma cell lines. 136
Growth arrest, apoptosis and potentiation of 5-fluorouracil and Raltitrexed cytotoxic effect induced by histone deacetylase inhibitor SAHA in colorectal cancer cells. 135
Inhibition of NF-kB activity potentiates ionizing radiation and cisplatin induced cell killing of anaplastic thyroid carcinoma cells AACR Meeting Abstracts, Apr 2006; 2006: 1038. 134
21st ISoP Annual Meeting “A New Era of Pharmacovigilance: Challenges and Opportunities” 20–23 September 2022 Verona, Italy 132
Theophylline-induced apoptosis is paralleled by protein kinase A-dependent tissue transglutaminase activation in cancer cells. 132
Measurement of neovascularization is an independent prognosticator of survival in node-negative breast cancer patients with long-lerm follow-up. 131
TESI DI DOTTORATO: Hereditary and familial breast and ovarian cancer: spectrum of related tumors. CANDIDATO: M.Pensabene. RELATORE: S.Pepe 131
Enzastaurin inhibits tumors sensitive and resistant to anti-EGFR drugs 131
Phase I-II study of sequential combination of XELOX and bevacizumab plus erlotinib (XELOX-TARAV) in first line colorectal patients:Run in phase I part 131
PRECLINICAL AND PHASE I STUDY OF OXALIPLATIN AND TOPOTECAN IN COMBINATION IN HUMAN CANCER. 131
Suppression of malignancy targeting the intracellular signal transducing proteins of cAMP: the use of site selective cAMP analogs, antisense strategy, and gene-transfer. 129
Synerglstic antltumor effect by novel modified oligonucleotides targeting PKAI combined with cytotoxic drugs or monoclonal antibodies. 129
Cell ploidy in 19 Wilms tumors by flow-cytometry of cell suspensions prepared from paraffina embedded sections. 128
Synergistic inhibition of growth and induction of apoptosis by 8-chloro-cAMP and paclitaxel or cisplatin in human cancer cells. 126
POLY(ADENOSINE DIPHOSPHATE-RIBOSE) POLYMERASE 1 EXPRESSION IN MALIGNANT MELANOMAS FROM PHOTOEXPOSED AREAS OF THE HEAD AND NECK REGION. 126
Cooperative effect of 8-Cl-cAMP and rhGM-CSF on the differentiation of HL-60 human leukemia-cells. 126
The cancer spectrum related to hereditary and familial breast and ovarian cancers 125
Blast cells DNA content in childhood leukemias. 125
P53 expression in non-small-cell lung-cancer. Clinical and biological correlations. 125
Overexpression of the RIα subunit of Protein Kinase A confers hypersensitivity to topoisomerase II inhibitors and 8-Chloro-cyclic Adenosine 3′,5′-Monophosphate in chinese hamster ovary cells. 125
EGF-R tyrosyne kinase as new target in melanoma treatment; Synergistic effect of IFN alpha in combination with ZD1839 )Iressa) , an EGFR tyrosine kinase inhibitor. 125
IgE receptors. 124
Antisense DNA-targeting protein kinase A-RIA subunit: a novel approach to cancer treatment. 123
EGF activates an inducible survival response via the RAS -> Erk-1/2 pathway to counteract interferon-alfa-mediated apoptosis in epidermoid cancer cells. 123
Multidisciplinary Approach to Patient with Malignant Melanoma 123
KRAS mutations in advanced non-small cell lung cancer: From biology to novel therapeutic strategies 122
Interferon-alpha induces apoptosis in human KB cells through a stress-dependent mitogen activated protein kinase pathway death is antagonized by epidermal growth factor. 121
Phorbol-12-myristate-13-acetate (PMA) induces resistance of human melanoma cells to NK and LAK-mediated cytotoxicity. 121
Molecules and mechanisms to overcome oxidative stress inducing cardiovascular disease in cancer patients 121
Diagnostic utility of BRAFV600E mutation testing in thyroid nodules in elderly patients 120
Two mutations of BRCA2 gene at exon and splicing site in a woman who underwent oncogenetic counseling 120
Totale 16.866
Categoria #
all - tutte 77.642
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 77.642


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20221.181 4 0 3 35 30 39 15 54 189 161 141 510
2022/20231.923 190 91 53 246 271 420 2 169 357 10 74 40
2023/20241.135 80 136 66 27 67 142 276 61 28 39 47 166
2024/20252.370 78 33 52 94 147 364 392 242 317 102 243 306
2025/20269.864 572 1.670 1.421 380 953 565 1.400 278 593 822 230 980
2026/2027398 398 0 0 0 0 0 0 0 0 0 0 0
Totale 26.490