UniSa - IRIS Institutional Research Information System

PEPE, Stefano
 Distribuzione geografica
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Continente #
NA - Nord America 10.084
EU - Europa 2.053
AS - Asia 1.175
Continente sconosciuto - Info sul continente non disponibili 30
OC - Oceania 5
SA - Sud America 1
Totale 13.348
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Nazione #
US - Stati Uniti d'America 10.070
UA - Ucraina 753
CN - Cina 695
IT - Italia 491
VN - Vietnam 291
IE - Irlanda 266
DE - Germania 229
FI - Finlandia 153
TR - Turchia 139
SE - Svezia 84
IN - India 36
EU - Europa 30
GB - Regno Unito 24
FR - Francia 17
CA - Canada 13
AT - Austria 10
RU - Federazione Russa 8
IL - Israele 5
PL - Polonia 5
HK - Hong Kong 4
NL - Olanda 4
SG - Singapore 4
CZ - Repubblica Ceca 3
NZ - Nuova Zelanda 3
AU - Australia 2
LT - Lituania 2
BG - Bulgaria 1
BR - Brasile 1
ES - Italia 1
IR - Iran 1
NO - Norvegia 1
PA - Panama 1
RO - Romania 1
Totale 13.348
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Città #
Ann Arbor 2.854
Woodbridge 1.230
Wilmington 1.082
Jacksonville 916
Houston 888
Chandler 789
Princeton 664
Dong Ket 290
Beijing 286
Dublin 263
Ashburn 216
Andover 172
Nanjing 148
Izmir 138
Pellezzano 125
Boardman 122
Mestre 107
Düsseldorf 67
Fairfield 55
Nanchang 50
Shenyang 45
Hebei 44
Salerno 42
Naples 40
Jiaxing 36
Washington 34
Changsha 33
Pune 31
Falls Church 26
Tianjin 23
Los Angeles 21
Norwalk 21
New York 19
Venezia 17
Cambridge 15
Redwood City 15
Seattle 14
San Diego 13
Ottawa 12
Paris 11
Tappahannock 10
Vienna 10
Dearborn 8
London 8
Chicago 7
Napoli 7
Castellammare di Stabia 6
Indiana 6
San Francisco 6
Mercato San Severino 5
Milan 5
Mountain View 5
Rutigliano 5
Warsaw 5
Guangzhou 4
Hong Kong 4
Jinan 4
Ningbo 4
Redmond 4
Singapore 4
Yellow Springs 4
Ashdod 3
Auckland 3
Des Moines 3
Hangzhou 3
Munich 3
Rome 3
Saint Petersburg 3
Shanghai 3
Trieste 3
Zhengzhou 3
Amsterdam 2
Baltimore 2
Bari 2
Cava De' Tirreni 2
Dello 2
Dormagen 2
Fisciano 2
Gainesville 2
Gesualdo 2
Islington 2
Male Hostice 2
Marcallo con Casone 2
Mele 2
Moscow 2
Mumbai 2
Novara 2
Oliveto Citra 2
Orange 2
Piano Di Sorrento 2
Pontelandolfo 2
San Giorgio A Cremano 2
San Martino Valle Caudina 2
San Michele di Serino 2
Scuola 2
Simi Valley 2
St Petersburg 2
Stella Cilento 2
Verona 2
Vilnius 2
Totale 11.183
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Nome #
Differential sensitivity to non-MHC-restricted rIL-2 activated lymphocyte killing of human mammary epithelial MCF-10A cells overexpressing oncogenes or PKA subunits. 328
The role of immunotherapy in solid tumors: report from the Campania Society of Oncology Immunotherapy (SCITO) meeting, Naples 2014. 238
Nuclear DNA content-derived parameters correlated with heterogeneous expression of p53 and bcl-2 proteins in clear cell renal carcinomas. 143
Phase I clinical study with 8-Chloro-cAMP and evaluation of immunological effects in cancer patients. 141
Procoagulant and fibrinolytic activity of human ovarian carcinoma cells in culture. 127
Anti-sense oligonucleotides directed against EGF-related growth factors enhance anti-proliferative effect of conventional anti-tumor drugs in human colon-cancer cells. 123
Reversal of adriamycin resistance by recombinant alpha-interferon in multidrug-resistant human colon carcinoma LoVo-doxorubicin cells. 119
Recombinant IFN-alfa 2b treatment activates poly (ADPR) polymerase-1 (PARP-1) in KB cancer cells. 119
NM23 gene expression correlates with cell growth rate and S-phase. 118
Regulation of the expression of Fc-epsilon-R in the human monocyte like cell line U937 by TPA and IgE. 116
Epidermal growth factor receptor (EGFr) expression in non-small cell lung carcinomas correlates with metastatic involvement of hilar and mediastinal lymph nodes in the squamous subtype 115
Retinoic acid induces neuronal differentiation of embryonal carcinoma cells by reducing proteasome-dependent proteolysis of the cyclin-dependent inhibitor p27. 109
Analysis of Differential miRNA Expression in Primary Tumor and Stroma of Colorectal Cancer Patients 107
Synergistic anti-tumour effect of raltitrexed and 5-fluorouracil plus folinic acid combination in human cancer cells. 106
Enhancement of antitumor activity of ionizing radiation by combined treatment with the selective EGFR-tyrosine kinase inhibitor ZD1839 (‘Iressa’) 106
ADDITION OF ERLOTINIB TO FLUROPYRIMIDINE-OXALIPLATIN-BASED CHEMOTHERAPY WITH OR WITHOUT BEVACIZUMAB: TWO SEQUENTIAL PHASE I TRIALS. 106
Cooperative inhibitory effect of novel mixed backbone oligonucleotide targeting Protein Kinase A in combination with docetaxel and anti-EGFR-Receptor antibody on human breast cancer cell growth. 104
Loss of thyrotropin regulation and trasforming growth factor beta-induced growth arrest in erbB-2 overexpressing rat thyroid cells. 103
Additive effects of c-erbB-2, c-Ha-ras, and transforming growth factor-a genes on in vitro transformation of human mammary epithelial cells. 103
DNA index of ovarian carcinomas from 56 different patients: in vivo, in vitro studies. 101
Reduction of RIAlpha subunit of cAMP-dependent Protein-Kinase expression induces growth-inhibition of human mammary epithelial-cells transformed by TGF-Alha, C-HA-RAS, and C-ErbB2 genes. 101
A phase I-II trial of gefitinib (IRESSA) and radiotherapy in patients with locally advanced inoperable squamous cell carcinoma of the head and neck (SCCHN) 101
Down-regulation of RI alpha subunit of cAMP-dependent protein kinase induces growth inhibition of human mammary epithelial cells transformed by c-Ha-ras and c-erbB-2 proto-oncogenes. 100
TSH-regulated growth and cell cycle distribution of thyroid cells involve type I isozyme of cAMP-dependent protein kinase 99
Type-I isoform of PKA is involved in the control of cell proliferation and oncogene transformation of human mammary epithelial cells.Therapeutic implications 99
TGFb inhibits rat thyroid cell proliferation without alterations in the expression of THS-induced cell cycle-related genes. Vol :pp , 98
A phase II study of biweekly oxaliplatin plus infusional 5-fluorouracil and folinic acid (FLFOX-4) as first-line treatment of advanced gastric cancer patients. 98
5-Aza-2'-Deoxycitidine induces growth-inhibition and up-regulation of epidermal-growth factor receptor on human epithelial cancer-cells 98
Oral antisense targeting protein kinase A type I causes antitumor and apoptotic effect in human cancer cells in vitro and in vivo and has cooperative activity in combination with antisense bcl-2. 96
Synergistic anti-proliferative and pro-apoptotic activity of combined therapy with bortezomib, a proteasome inhibitor, with anti-epidermal growth factor receptor (EGFR) drugs in human cancer cells. 95
Adjuvant treatment of diabetic foot 95
Growth inhibition of tumor cells by epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 is associated with upregulation of p27 and p21 cyclin-dependent kinase inhibitors. 95
Critical role of both p27kip1 and p21cip1/waf1 in the antiproliferative effect of ZD1839 (‘Iressa’), an epidermal growth factor receptor tyrosine kinase inhibitor, in head and neck squamous carcinoma cells. 94
DNA-flow cytometry (ploidy and S-phase fraction) as prognostic factor in a retrospectine series of 515 primary breast cancer. 94
The expression of proliferating cell nuclear antigen in paraffin sections of peripheral, node-negative non-small cell lung cancer. 94
Cell growth-inhibition and cell cycle perturbations induced by a new synthetic iminoquinone, 5H-pyridophenoxazin-5-one, in human breast carcinoma cell lines. 94
PRECLINICAL AND PHASE I STUDY OF OXALIPLATIN AND TOPOTECAN IN COMBINATION IN HUMAN CANCER. 94
Growth arrest, apoptosis and potentiation of 5-fluorouracil and Raltitrexed cytotoxic effect induced by histone deacetylase inhibitor SAHA in colorectal cancer cells. 93
Adjuvant Treatment for Locally Advanced Rectal Cancer Patients After Preoperative Chemoradiotherapy: When, and for Whom? 93
Modulation of thymidilate synthase and p53 expression by HDAC inhibitor vorinostat resulted in synergistic antitumor effect in combination with 5FU or raltitrexed. 91
Enzastaurin inhibits tumors sensitive and resistant to anti-EGFR drugs 91
Blast cells DNA content in childhood leukemias. 91
IgE receptors. 91
Predictive factors of response to neoadjuvant chemoradiotherapy in rectal cancer patirnts. 90
Suppression of malignancy targeting the intracellular signal transducing proteins of cAMP: the use of site selective cAMP analogs, antisense strategy, and gene-transfer. 90
Overexpression of wild-type p53 ovverrides the mitogenic effect of the RIa subunit of protein kinase A in human breast cells. 89
POLY(ADENOSINE DIPHOSPHATE-RIBOSE) POLYMERASE 1 EXPRESSION IN MALIGNANT MELANOMAS FROM PHOTOEXPOSED AREAS OF THE HEAD AND NECK REGION. 89
8-Cl-cAMP in differentiation therapy: The reversal and suppression of malignancy targeting the intracellular transducing proteins of cAMP. 88
Multidisciplinary Approach to Patient with Malignant Melanoma 87
Epidermal growth factor (EGFR) and Transferrin (TRFR) receptor upregulation is induced by arabinoside cytosine (ARA-C) on human tumor cells. 86
Activity and safety of pegylated liposomal doxorubicin, 5-fluorouracil and folinic acid in inoperable hepatocellular carcinoma: a phase II study. 86
EGF-R tyrosyne kinase as new target in melanoma treatment; Synergistic effect of IFN alpha in combination with ZD1839 )Iressa) , an EGFR tyrosine kinase inhibitor. 86
Cell ploidy in 19 Wilms tumors by flow-cytometry of cell suspensions prepared from paraffina embedded sections. 86
EPIGENETIC FACTORS IN HEREDITARY BREAST CANCER 85
The farnesyltransferase inhibitor R115777 (Zanestra) synergizes with ionizing radiation in inducing cell cycle perturbation and growth inhibition of human epidermoid head and neck cancer cells. 85
Bevacizumab maintenance in metastatic colorectal cancer: How long?. 85
Inhibition of NF-kB activity potentiates ionizing radiation and cisplatin induced cell killing of anaplastic thyroid carcinoma cells AACR Meeting Abstracts, Apr 2006; 2006: 1038. 84
Synerglstic antltumor effect by novel modified oligonucleotides targeting PKAI combined with cytotoxic drugs or monoclonal antibodies. 83
Key role of the cyclin-dependent kinase inhibitor p27kip1 for embryonal carcinoma cell survival and differentiation. 82
P53 expression in non-small-cell lung-cancer. Clinical and biological correlations. 82
Synergistic antitumor activity of the combination of the multi-targetes tyrosine kinase inhibitor sorafenib and of EGFR inhibitors in human colon and lung cancer cell lines. 82
Antisense DNA-targeting protein kinase A-RIA subunit: a novel approach to cancer treatment. 81
Synergistic inhibition of growth and induction of apoptosis by 8-chloro-cAMP and paclitaxel or cisplatin in human cancer cells. 81
Antitumor activity of sequential treatment with topotecan and anti-epidermal growth factor receptor monoclonal antibody C225. 81
Diagnostic utility of BRAFV600E mutation testing in thyroid nodules in elderly patients 80
Antisense-protein kinase A: a single-gene-based therapeutic approach. 80
Markers of cell-proliferation (p21, PCNA, S-Phase) as prognostic factors in papillary thyroid carcinoma. 80
Antitumor Agents. 5. Synthesis, structure−activity relationships, and biological evaluation of dimethyl-5H-pyridophenoxazin-5-ones, tetrahydro-5H-benzopyridophenoxazin-5-ones, and 5H-benzopyridophenoxazin-5-ones with potent antiproliferative activity. 80
p53 alterations in non-small cell lung cancers correlate with metastatic involvement of hilar and mediastinal lymph nodes. 79
Flow-cytometric detection of the RI-alpha subunit of Type-I cAMP-dependent protein-kinase in human-cells 79
Overexpression of the RIα subunit of Protein Kinase A confers hypersensitivity to topoisomerase II inhibitors and 8-Chloro-cyclic Adenosine 3′,5′-Monophosphate in chinese hamster ovary cells. 79
REPLY TO BRCA2 SPLICE SITE MUTATIONS IN ITALIAN BREAST/OVARIAN CANCER FAMILY. 79
Theophylline-induced apoptosis is paralleled by protein kinase A-dependent tissue transglutaminase activation in cancer cells. 79
A phase I/II trial of gefitinib and radiotherapy in patients with locally advanced inoperable squamous cell carcinoma of the head and neck. 78
Predictive factors of complete response to neoadjuvant chemoradiotherapy in patients with rectal cancer. 78
A phase II study of biweekly oxaliplatin plus infusional 5-fluorouracil and folinic acid (FOLFOX-4) as first-line treatment of advanced gastric cancer patients. 78
Unhydrolyzable analogs of Adenosine 3'/5'-monophosphate demonstrating growth-inhibition and differentiation in human cancer-cells. 78
Counteracting resistance to treatments in solid tumors. 78
EGF activates an inducible survival response via the RAS -> Erk-1/2 pathway to counteract interferon-alfa-mediated apoptosis in epidermoid cancer cells. 77
cAMP-dependent protein kinase: role in normal and malignant growth. 76
8-Chloro-cAMP enhances the growth inhibitory effect of cytotoxic drugs in human colon cancer cells 76
Neo-adjuvant treatment of rectal cancer with capecitabine and oxaliplatin in combination with radiotherapy: a phase II study. 76
Cooperative effect of 8-Cl-cAMP and rhGM-CSF on the differentiation of HL-60 human leukemia-cells. 76
Quality control for the evaluation of the S-phase fraction by flow cytometry: a multicentric study. 75
Capecitabine plus weekly oxaliplatin in gastrointestinal tumors: a phase I study. 75
TESI DI DOTTORATO: Hereditary and familial breast and ovarian cancer: spectrum of related tumors. CANDIDATO: M.Pensabene. RELATORE: S.Pepe 75
Synergistic antitumor activity of epidermal growth factor receptor tyrosine kinase inhibitor gefitinib and IFN-A in head and neck cancer cells in vitro and in vivo 74
The cancer spectrum related to hereditary and familial breast and ovarian cancers 74
Retroviral vector-mediated overexpression of the RIIbeta subunit of the cAMP-dependent protein kinase induces differentiation in human leukemia cells and reverts the transformed phenotype of mouse fibroblasts. 74
Twenty-year results of the Naples GUN randomized trial: predictive factors of adjuvant tamoxifen efficacy in early breast cancer. 74
Use of FTA cards for the storage of breast carcinoma nucleic acid on fine-needle aspiration samples 74
Interferon-alpha induces apoptosis in human KB cells through a stress-dependent mitogen activated protein kinase pathway death is antagonized by epidermal growth factor. 73
Measurement of neovascularization is an independent prognosticator of survival in node-negative breast cancer patients with long-lerm follow-up. 73
Non lymphomatous clonal B-Cell populations in enlarged lymph nodes in acquired immunodeficiency syndrome. 73
Two mutations of BRCA2 gene at exon and splicing site in a woman who underwent oncogenetic counseling 72
Mitozolomide activity on human cancer cells "in vitro". 72
Phorbol-12-myristate-13-acetate (PMA) induces resistance of human melanoma cells to NK and LAK-mediated cytotoxicity. 72
Introducing an autophosphorylation site mutation in the RII-beta regulatory subunit of cAMP-dependent Protein-Kinase abolishes the RII-beta -mediated regulatory function. 72
The RIalfa subunit of protein kinase A controls serum dependency and entry into cell cycle of human mammary epithelial cells. 71
Bryostatin 1 enhances lymphokine activated killer sensitivity and modulates the b1 integrin profile of cultured human tumor cells. 71
Totale 9.345
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Categoria #
all - tutte 30.750
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 30.750
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/2019221 0 0 0 0 0 0 0 0 0 55 157 9
2019/20201.378 391 7 162 8 156 73 157 8 154 45 195 22
2020/20211.349 13 150 154 14 163 30 170 11 152 2 167 323
2021/20221.181 4 0 3 35 30 38 15 54 189 161 141 511
2022/20231.916 190 91 53 244 270 419 2 169 355 10 73 40
2023/2024918 80 135 66 27 67 142 276 61 28 36 0 0
Totale 13.600