PEPE, Stefano
 Distribuzione geografica
Continente #
NA - Nord America 11.524
AS - Asia 5.810
EU - Europa 2.990
SA - Sud America 538
AF - Africa 60
Continente sconosciuto - Info sul continente non disponibili 34
OC - Oceania 11
Totale 20.967
Nazione #
US - Stati Uniti d'America 11.427
HK - Hong Kong 2.500
SG - Singapore 1.347
CN - Cina 1.022
UA - Ucraina 764
IT - Italia 622
BR - Brasile 475
DE - Germania 435
VN - Vietnam 375
RU - Federazione Russa 328
IE - Irlanda 266
FI - Finlandia 233
KR - Corea 179
TR - Turchia 153
SE - Svezia 94
IN - India 72
GB - Regno Unito 67
CA - Canada 57
AT - Austria 41
EU - Europa 30
AR - Argentina 27
JP - Giappone 27
ID - Indonesia 24
IQ - Iraq 24
NL - Olanda 23
CZ - Repubblica Ceca 22
ES - Italia 22
FR - Francia 22
BD - Bangladesh 20
MX - Messico 20
PL - Polonia 17
ZA - Sudafrica 12
EC - Ecuador 11
IL - Israele 11
JO - Giordania 10
MA - Marocco 10
PK - Pakistan 10
CR - Costa Rica 8
DZ - Algeria 7
TN - Tunisia 7
UZ - Uzbekistan 7
CO - Colombia 6
AL - Albania 5
AU - Australia 5
EG - Egitto 5
RO - Romania 5
VE - Venezuela 5
AE - Emirati Arabi Uniti 4
BG - Bulgaria 4
CH - Svizzera 4
CL - Cile 4
PE - Perù 4
PY - Paraguay 4
SA - Arabia Saudita 4
GR - Grecia 3
KG - Kirghizistan 3
LT - Lituania 3
NP - Nepal 3
NZ - Nuova Zelanda 3
PA - Panama 3
XK - ???statistics.table.value.countryCode.XK??? 3
AZ - Azerbaigian 2
BF - Burkina Faso 2
DK - Danimarca 2
GT - Guatemala 2
IR - Iran 2
JM - Giamaica 2
KE - Kenya 2
LB - Libano 2
MD - Moldavia 2
MY - Malesia 2
NO - Norvegia 2
SN - Senegal 2
ZM - Zambia 2
AG - Antigua e Barbuda 1
BH - Bahrain 1
BJ - Benin 1
BS - Bahamas 1
BW - Botswana 1
BY - Bielorussia 1
CI - Costa d'Avorio 1
CM - Camerun 1
CV - Capo Verde 1
CW - ???statistics.table.value.countryCode.CW??? 1
DO - Repubblica Dominicana 1
EE - Estonia 1
GF - Guiana Francese 1
KH - Cambogia 1
KI - Kiribati 1
KZ - Kazakistan 1
MK - Macedonia 1
ML - Mali 1
MM - Myanmar 1
MN - Mongolia 1
MU - Mauritius 1
MZ - Mozambico 1
NA - Namibia 1
NG - Nigeria 1
NR - Nauru 1
PR - Porto Rico 1
Totale 20.960
Città #
Ann Arbor 2.852
Hong Kong 2.500
Woodbridge 1.235
Wilmington 1.081
Jacksonville 921
Houston 909
Chandler 793
Princeton 663
Singapore 588
Dallas 557
Ashburn 358
Beijing 316
Dong Ket 290
Dublin 262
Munich 176
Andover 172
Nanjing 150
Izmir 145
Pellezzano 125
Boardman 124
Mestre 107
Moscow 87
Naples 74
Los Angeles 70
Düsseldorf 67
New York 61
Fairfield 55
Nanchang 50
Shenyang 46
Hebei 44
Salerno 43
São Paulo 43
Helsinki 42
Changsha 38
Jiaxing 37
Washington 35
Pune 31
Ho Chi Minh City 30
Nuremberg 29
The Dalles 29
Turku 28
Brooklyn 26
Falls Church 26
Santa Clara 26
Tianjin 26
Columbus 25
Chicago 24
Tokyo 24
Vienna 24
Seattle 23
Norwalk 22
San Francisco 22
Montreal 20
London 19
Hanoi 18
Brno 17
Venezia 17
Cambridge 16
Warsaw 16
Redwood City 15
Denver 14
Orem 14
Brasília 13
Chennai 13
Guangzhou 13
Boston 12
Milan 12
Ottawa 12
Paris 12
San Diego 12
Baghdad 11
Shanghai 11
Amman 10
Atlanta 10
Council Bluffs 10
Fisciano 10
Rome 10
Stockholm 10
Tappahannock 10
Poplar 9
Rio de Janeiro 9
Seoul 9
Amsterdam 8
Dearborn 8
Porto Alegre 8
Belo Horizonte 7
Charlotte 7
Indiana 7
Jakarta 7
Mexico City 7
Napoli 7
Phoenix 7
Sarno 7
Tashkent 7
Tel Aviv 7
Toronto 7
Biên Hòa 6
Castellammare di Stabia 6
Haiphong 6
Jackson 6
Totale 16.040
Nome #
Epidermal growth factor receptor (EGFr) expression in non-small cell lung carcinomas correlates with metastatic involvement of hilar and mediastinal lymph nodes in the squamous subtype 586
Prior Anti-Angiogenic TKI-Based Treatment as Potential Predisposing Factor to Nivolumab-Mediated Recurrent Thyroid Disorder Adverse Events in mRCC Patients: A Case Series 494
Bispecific Antibodies: A Novel Approach for the Treatment of Solid Tumors 483
Differential sensitivity to non-MHC-restricted rIL-2 activated lymphocyte killing of human mammary epithelial MCF-10A cells overexpressing oncogenes or PKA subunits. 346
Abstract 3132: Single nucleotide polymorphisms (SNPs) in PD-L1 as predictive biomarkers for checkpoint inhibitor based-immunotherapy in caucasian patients with advanced NSCLC 280
Measurement of neovascularization is an independent prognosticator of survival in node-negative breast cancer patients with long-term follow-up 279
Synergistic antitumor activity of epidermal growth factor receptor tyrosine kinase inhibitor gefitinib and IFN-A in head and neck cancer cells in vitro and in vivo 276
The role of immunotherapy in solid tumors: report from the Campania Society of Oncology Immunotherapy (SCITO) meeting, Naples 2014. 261
Evaluation of Potential Predictive Biomarkers for Defining Brain Radiotherapy Efficacy in Non-Small Cell Lung Cancer Patients with Brain Metastases: A Case Report and a Narrative Review 212
Radioresistance in head and neck squamous cell carcinoma: Biological bases and therapeutic implications. 190
Overexpression of wild-type p53 ovverrides the mitogenic effect of the RIa subunit of protein kinase A in human breast cells. 185
rs822336 as a predictive biomarker for anti-PD-1/PD-L1 immunotherapy in advanced NSCLC: Unraveling molecular mechanisms 171
Nuclear DNA content-derived parameters correlated with heterogeneous expression of p53 and bcl-2 proteins in clear cell renal carcinomas. 160
Phase I clinical study with 8-Chloro-cAMP and evaluation of immunological effects in cancer patients. 160
ADDITION OF ERLOTINIB TO FLUROPYRIMIDINE-OXALIPLATIN-BASED CHEMOTHERAPY WITH OR WITHOUT BEVACIZUMAB: TWO SEQUENTIAL PHASE I TRIALS. 154
A genotyping/phenotyping approach with careful clinical monitoring to manage the fluoropyrimidines-based therapy: Clinical cases and systematic review of the literature 154
Additive effects of c-erbB-2, c-Ha-ras, and transforming growth factor-a genes on in vitro transformation of human mammary epithelial cells. 153
A phase I-II trial of gefitinib (IRESSA) and radiotherapy in patients with locally advanced inoperable squamous cell carcinoma of the head and neck (SCCHN) 153
Adjuvant treatment of diabetic foot 151
5-Aza-2'-Deoxycitidine induces growth-inhibition and up-regulation of epidermal-growth factor receptor on human epithelial cancer-cells 149
Anti-sense oligonucleotides directed against EGF-related growth factors enhance anti-proliferative effect of conventional anti-tumor drugs in human colon-cancer cells. 144
Procoagulant and fibrinolytic activity of human ovarian carcinoma cells in culture. 144
A phase II study of biweekly oxaliplatin plus infusional 5-fluorouracil and folinic acid (FLFOX-4) as first-line treatment of advanced gastric cancer patients. 143
Modulation of thymidilate synthase and p53 expression by HDAC inhibitor vorinostat resulted in synergistic antitumor effect in combination with 5FU or raltitrexed. 139
Poly(ADPR)polymerase-1 signalling of the DNA damage induced by DNA topoisomerase I poison in D54p53wt and U251p53mut glioblastoma cell lines. 139
Reversal of adriamycin resistance by recombinant alpha-interferon in multidrug-resistant human colon carcinoma LoVo-doxorubicin cells. 138
Enhancement of antitumor activity of ionizing radiation by combined treatment with the selective EGFR-tyrosine kinase inhibitor ZD1839 (‘Iressa’) 138
Tumori Eredo-Familiari 136
Activity and safety of pegylated liposomal doxorubicin, 5-fluorouracil and folinic acid in inoperable hepatocellular carcinoma: a phase II study. 135
Recombinant IFN-alfa 2b treatment activates poly (ADPR) polymerase-1 (PARP-1) in KB cancer cells. 134
Retinoic acid induces neuronal differentiation of embryonal carcinoma cells by reducing proteasome-dependent proteolysis of the cyclin-dependent inhibitor p27. 134
8-Cl-cAMP in differentiation therapy: The reversal and suppression of malignancy targeting the intracellular transducing proteins of cAMP. 134
NM23 gene expression correlates with cell growth rate and S-phase. 133
Adjuvant Treatment for Locally Advanced Rectal Cancer Patients After Preoperative Chemoradiotherapy: When, and for Whom? 133
Regulation of the expression of Fc-epsilon-R in the human monocyte like cell line U937 by TPA and IgE. 131
TSH-regulated growth and cell cycle distribution of thyroid cells involve type I isozyme of cAMP-dependent protein kinase 129
Down-regulation of RI alpha subunit of cAMP-dependent protein kinase induces growth inhibition of human mammary epithelial cells transformed by c-Ha-ras and c-erbB-2 proto-oncogenes. 128
Antitumor activity of BRAF inhibitor and IFN×alpha; Combination in BRAF-mutant melanoma 128
8-Chloro-cAMP enhances the growth inhibitory effect of cytotoxic drugs in human colon cancer cells 126
A phase I/II trial of gefitinib and radiotherapy in patients with locally advanced inoperable squamous cell carcinoma of the head and neck. 125
A phase II study of biweekly oxaliplatin plus infusional 5-fluorouracil and folinic acid (FOLFOX-4) as first-line treatment of advanced gastric cancer patients. 125
Synergistic anti-tumour effect of raltitrexed and 5-fluorouracil plus folinic acid combination in human cancer cells. 124
Analysis of Differential miRNA Expression in Primary Tumor and Stroma of Colorectal Cancer Patients 123
Sequence-dependent, synergistic antiproliferative and proapoptotic effects of the combination of cytotoxic drugs and enzastaurin, a protein kinase C beta inhibitor, in non-small cell lung cancer cells. 121
Non lymphomatous clonal B-Cell populations in enlarged lymph nodes in acquired immunodeficiency syndrome. 121
Cooperative inhibitory effect of novel mixed backbone oligonucleotide targeting Protein Kinase A in combination with docetaxel and anti-EGFR-Receptor antibody on human breast cancer cell growth. 120
Abstract 4017: Anti-tumor activity of a BRAF inhibitor and IFNα combination in BRAF mutant melanoma 120
Loss of thyrotropin regulation and trasforming growth factor beta-induced growth arrest in erbB-2 overexpressing rat thyroid cells. 117
Oral antisense targeting protein kinase A type I causes antitumor and apoptotic effect in human cancer cells in vitro and in vivo and has cooperative activity in combination with antisense bcl-2. 117
Growth inhibition of tumor cells by epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 is associated with upregulation of p27 and p21 cyclin-dependent kinase inhibitors. 116
A specific miRNA signature correlates with complete pathological response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer 116
Synergistic anti-proliferative and pro-apoptotic activity of combined therapy with bortezomib, a proteasome inhibitor, with anti-epidermal growth factor receptor (EGFR) drugs in human cancer cells. 115
TGFb inhibits rat thyroid cell proliferation without alterations in the expression of THS-induced cell cycle-related genes. Vol :pp , 115
Type-I isoform of PKA is involved in the control of cell proliferation and oncogene transformation of human mammary epithelial cells.Therapeutic implications 115
Reduction of RIAlpha subunit of cAMP-dependent Protein-Kinase expression induces growth-inhibition of human mammary epithelial-cells transformed by TGF-Alha, C-HA-RAS, and C-ErbB2 genes. 115
DNA index of ovarian carcinomas from 56 different patients: in vivo, in vitro studies. 114
Altre Neoplasie 114
Cell growth-inhibition and cell cycle perturbations induced by a new synthetic iminoquinone, 5H-pyridophenoxazin-5-one, in human breast carcinoma cell lines. 114
Theophylline-induced apoptosis is paralleled by protein kinase A-dependent tissue transglutaminase activation in cancer cells. 114
Farsi promotori di salute: “Safe Sun Coast” 114
Critical role of both p27kip1 and p21cip1/waf1 in the antiproliferative effect of ZD1839 (‘Iressa’), an epidermal growth factor receptor tyrosine kinase inhibitor, in head and neck squamous carcinoma cells. 113
Expression of teratocarcinoma-derived growth factor-1 (TDGF-1) in testis germ cell tumors and its effects on growth and differentiation of embryonal carcinoma cell line NTERA2/D1. 113
The expression of proliferating cell nuclear antigen in paraffin sections of peripheral, node-negative non-small cell lung cancer. 112
Inhibition of NF-kB activity potentiates ionizing radiation and cisplatin induced cell killing of anaplastic thyroid carcinoma cells AACR Meeting Abstracts, Apr 2006; 2006: 1038. 112
Enhanced Expression of CD47 Is Associated With Off-Target Resistance to Tyrosine Kinase Inhibitor Gefitinib in NSCLC 112
DNA-flow cytometry (ploidy and S-phase fraction) as prognostic factor in a retrospectine series of 515 primary breast cancer. 111
Predictive factors of response to neoadjuvant chemoradiotherapy in rectal cancer patirnts. 110
Enzastaurin inhibits tumors sensitive and resistant to anti-EGFR drugs 109
A Specific miRNA Signature Correlates with Complete Pathological Response to Neoadjuvant Chemoradiotherapy in Locally Advanced Rectal Cancer. 109
Blast cells DNA content in childhood leukemias. 109
PRECLINICAL AND PHASE I STUDY OF OXALIPLATIN AND TOPOTECAN IN COMBINATION IN HUMAN CANCER. 108
Growth arrest, apoptosis and potentiation of 5-fluorouracil and Raltitrexed cytotoxic effect induced by histone deacetylase inhibitor SAHA in colorectal cancer cells. 107
Neo-adjuvant treatment of rectal cancer with capecitabine and oxaliplatin in combination with radiotherapy: a phase II study. 106
Suppression of malignancy targeting the intracellular signal transducing proteins of cAMP: the use of site selective cAMP analogs, antisense strategy, and gene-transfer. 106
Cell ploidy in 19 Wilms tumors by flow-cytometry of cell suspensions prepared from paraffina embedded sections. 106
POLY(ADENOSINE DIPHOSPHATE-RIBOSE) POLYMERASE 1 EXPRESSION IN MALIGNANT MELANOMAS FROM PHOTOEXPOSED AREAS OF THE HEAD AND NECK REGION. 104
IgE receptors. 103
Multidisciplinary Approach to Patient with Malignant Melanoma 103
Synergistic inhibition of growth and induction of apoptosis by 8-chloro-cAMP and paclitaxel or cisplatin in human cancer cells. 102
The farnesyltransferase inhibitor R115777 (Zanestra) synergizes with ionizing radiation in inducing cell cycle perturbation and growth inhibition of human epidermoid head and neck cancer cells. 102
Interferon-alpha induces apoptosis in human KB cells through a stress-dependent mitogen activated protein kinase pathway death is antagonized by epidermal growth factor. 101
TESI DI DOTTORATO: Hereditary and familial breast and ovarian cancer: spectrum of related tumors. CANDIDATO: M.Pensabene. RELATORE: S.Pepe 101
Bevacizumab maintenance in metastatic colorectal cancer: How long?. 101
Abstract 3703: PDGFRα up-regulation mediated by Sonic Hedgehog Pathway activation leads to BRAF inhibitor resistance in melanoma cells with BRAF mutation 101
Antisense-protein kinase A: a single-gene-based therapeutic approach. 100
Predictive factors of complete response to neoadjuvant chemoradiotherapy in patients with rectal cancer. 98
P53 expression in non-small-cell lung-cancer. Clinical and biological correlations. 98
Phase I-II study of sequential combination of XELOX and bevacizumab plus erlotinib (XELOX-TARAV) in first line colorectal patients:Run in phase I part 98
EGF-R tyrosyne kinase as new target in melanoma treatment; Synergistic effect of IFN alpha in combination with ZD1839 )Iressa) , an EGFR tyrosine kinase inhibitor. 98
p53 alterations in non-small cell lung cancers correlate with metastatic involvement of hilar and mediastinal lymph nodes. 97
Measurement of neovascularization is an independent prognosticator of survival in node-negative breast cancer patients with long-lerm follow-up. 97
Epidermal growth factor (EGFR) and Transferrin (TRFR) receptor upregulation is induced by arabinoside cytosine (ARA-C) on human tumor cells. 97
EPIGENETIC FACTORS IN HEREDITARY BREAST CANCER 97
Synerglstic antltumor effect by novel modified oligonucleotides targeting PKAI combined with cytotoxic drugs or monoclonal antibodies. 97
Antisense DNA-targeting protein kinase A-RIA subunit: a novel approach to cancer treatment. 96
Twenty-year results of the Naples GUN randomized trial: predictive factors of adjuvant tamoxifen efficacy in early breast cancer. 96
Antitumor activity of sequential treatment with topotecan and anti-epidermal growth factor receptor monoclonal antibody C225. 95
EGF activates an inducible survival response via the RAS -> Erk-1/2 pathway to counteract interferon-alfa-mediated apoptosis in epidermoid cancer cells. 95
Retroviral vector-mediated overexpression of the RIIbeta subunit of the cAMP-dependent protein kinase induces differentiation in human leukemia cells and reverts the transformed phenotype of mouse fibroblasts. 95
Markers of cell-proliferation (p21, PCNA, S-Phase) as prognostic factors in papillary thyroid carcinoma. 95
Totale 14.148
Categoria #
all - tutte 65.745
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 65.745


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021858 0 0 0 0 0 30 171 11 153 2 168 323
2021/20221.181 4 0 3 35 30 39 15 54 189 161 141 510
2022/20231.923 190 91 53 246 271 420 2 169 357 10 74 40
2023/20241.135 80 136 66 27 67 142 276 61 28 39 47 166
2024/20252.370 78 33 52 94 147 364 392 242 317 102 243 306
2025/20265.016 572 1.670 1.421 380 953 20 0 0 0 0 0 0
Totale 21.244