PEPE, Stefano
 Distribuzione geografica
Continente #
NA - Nord America 13.271
AS - Asia 7.173
EU - Europa 3.392
SA - Sud America 731
AF - Africa 118
Continente sconosciuto - Info sul continente non disponibili 36
OC - Oceania 15
Totale 24.736
Nazione #
US - Stati Uniti d'America 13.143
HK - Hong Kong 2.558
SG - Singapore 2.032
CN - Cina 1.140
UA - Ucraina 769
IT - Italia 712
VN - Vietnam 602
BR - Brasile 583
DE - Germania 460
RU - Federazione Russa 336
IE - Irlanda 272
FI - Finlandia 238
FR - Francia 217
KR - Corea 183
TR - Turchia 171
IN - India 124
GB - Regno Unito 98
SE - Svezia 96
BD - Bangladesh 66
CA - Canada 65
AR - Argentina 59
JP - Giappone 55
IQ - Iraq 44
AT - Austria 43
ID - Indonesia 37
NL - Olanda 37
PK - Pakistan 32
MX - Messico 31
EU - Europa 30
ES - Italia 26
ZA - Sudafrica 24
UZ - Uzbekistan 23
CZ - Repubblica Ceca 22
EC - Ecuador 21
PL - Polonia 21
CO - Colombia 19
MA - Marocco 19
JO - Giordania 18
TN - Tunisia 18
CL - Cile 14
IL - Israele 14
VE - Venezuela 14
DZ - Algeria 12
KE - Kenya 11
CR - Costa Rica 10
SA - Arabia Saudita 10
AU - Australia 9
MY - Malesia 8
PE - Perù 7
PH - Filippine 7
PY - Paraguay 7
AL - Albania 6
EG - Egitto 6
KG - Kirghizistan 6
RO - Romania 6
AE - Emirati Arabi Uniti 5
AZ - Azerbaigian 5
BG - Bulgaria 5
CH - Svizzera 5
JM - Giamaica 5
OM - Oman 5
XK - ???statistics.table.value.countryCode.XK??? 5
NG - Nigeria 4
PA - Panama 4
BO - Bolivia 3
ET - Etiopia 3
GR - Grecia 3
LB - Libano 3
LT - Lituania 3
MD - Moldavia 3
NO - Norvegia 3
NP - Nepal 3
NZ - Nuova Zelanda 3
SN - Senegal 3
SY - Repubblica araba siriana 3
UY - Uruguay 3
AO - Angola 2
BF - Burkina Faso 2
BH - Bahrain 2
DK - Danimarca 2
DO - Repubblica Dominicana 2
EE - Estonia 2
GT - Guatemala 2
HN - Honduras 2
IR - Iran 2
KH - Cambogia 2
KZ - Kazakistan 2
MK - Macedonia 2
MN - Mongolia 2
PT - Portogallo 2
TH - Thailandia 2
TT - Trinidad e Tobago 2
TW - Taiwan 2
ZM - Zambia 2
AG - Antigua e Barbuda 1
AM - Armenia 1
BA - Bosnia-Erzegovina 1
BJ - Benin 1
BS - Bahamas 1
BT - Bhutan 1
Totale 24.712
Città #
Ann Arbor 2.852
Hong Kong 2.553
Woodbridge 1.235
Singapore 1.138
Wilmington 1.081
Jacksonville 921
Houston 914
San Jose 900
Chandler 793
Princeton 663
Dallas 561
Ashburn 539
Beijing 338
Dong Ket 290
Dublin 268
Council Bluffs 211
Lauterbourg 183
Munich 176
Andover 172
The Dalles 168
Nanjing 150
Izmir 145
Boardman 125
Pellezzano 125
Ho Chi Minh City 111
Mestre 107
Moscow 87
Los Angeles 85
Naples 85
Hanoi 77
New York 75
Düsseldorf 67
Santa Clara 62
Fairfield 55
São Paulo 53
Nanchang 50
Tokyo 49
Helsinki 47
Salerno 46
Shenyang 46
Hebei 44
Changsha 38
Jiaxing 37
Washington 36
Orem 33
Chicago 32
Pune 32
Nuremberg 29
Turku 28
Brooklyn 26
Columbus 26
Falls Church 26
Tianjin 26
Vienna 25
Frankfurt am Main 23
Norwalk 23
Seattle 23
Montreal 22
San Francisco 22
Tashkent 21
Brasília 20
London 20
Warsaw 20
Chennai 19
Denver 18
Amman 17
Amsterdam 17
Baghdad 17
Brno 17
Venezia 17
Cambridge 16
Rio de Janeiro 16
Boston 15
Da Nang 15
Haiphong 15
Redwood City 15
Atlanta 14
Guangzhou 14
Milan 14
Biên Hòa 13
Fisciano 13
Mumbai 13
Paris 13
Rome 13
Shanghai 13
Manchester 12
Ottawa 12
Quito 12
San Diego 12
Stockholm 12
Belo Horizonte 11
Phoenix 11
Poplar 11
Toronto 11
Mexico City 10
Nairobi 10
Tappahannock 10
Dearborn 9
Porto Alegre 9
Seoul 9
Totale 18.730
Nome #
Epidermal growth factor receptor (EGFr) expression in non-small cell lung carcinomas correlates with metastatic involvement of hilar and mediastinal lymph nodes in the squamous subtype 605
Prior Anti-Angiogenic TKI-Based Treatment as Potential Predisposing Factor to Nivolumab-Mediated Recurrent Thyroid Disorder Adverse Events in mRCC Patients: A Case Series 532
Bispecific Antibodies: A Novel Approach for the Treatment of Solid Tumors 509
Differential sensitivity to non-MHC-restricted rIL-2 activated lymphocyte killing of human mammary epithelial MCF-10A cells overexpressing oncogenes or PKA subunits. 360
Abstract 3132: Single nucleotide polymorphisms (SNPs) in PD-L1 as predictive biomarkers for checkpoint inhibitor based-immunotherapy in caucasian patients with advanced NSCLC 318
Measurement of neovascularization is an independent prognosticator of survival in node-negative breast cancer patients with long-term follow-up 300
Synergistic antitumor activity of epidermal growth factor receptor tyrosine kinase inhibitor gefitinib and IFN-A in head and neck cancer cells in vitro and in vivo 295
The role of immunotherapy in solid tumors: report from the Campania Society of Oncology Immunotherapy (SCITO) meeting, Naples 2014. 287
Evaluation of Potential Predictive Biomarkers for Defining Brain Radiotherapy Efficacy in Non-Small Cell Lung Cancer Patients with Brain Metastases: A Case Report and a Narrative Review 246
Radioresistance in head and neck squamous cell carcinoma: Biological bases and therapeutic implications. 209
Overexpression of wild-type p53 ovverrides the mitogenic effect of the RIa subunit of protein kinase A in human breast cells. 200
rs822336 as a predictive biomarker for anti-PD-1/PD-L1 immunotherapy in advanced NSCLC: Unraveling molecular mechanisms 191
A phase I-II trial of gefitinib (IRESSA) and radiotherapy in patients with locally advanced inoperable squamous cell carcinoma of the head and neck (SCCHN) 183
A genotyping/phenotyping approach with careful clinical monitoring to manage the fluoropyrimidines-based therapy: Clinical cases and systematic review of the literature 182
Phase I clinical study with 8-Chloro-cAMP and evaluation of immunological effects in cancer patients. 180
Nuclear DNA content-derived parameters correlated with heterogeneous expression of p53 and bcl-2 proteins in clear cell renal carcinomas. 175
Additive effects of c-erbB-2, c-Ha-ras, and transforming growth factor-a genes on in vitro transformation of human mammary epithelial cells. 174
Adjuvant treatment of diabetic foot 174
ADDITION OF ERLOTINIB TO FLUROPYRIMIDINE-OXALIPLATIN-BASED CHEMOTHERAPY WITH OR WITHOUT BEVACIZUMAB: TWO SEQUENTIAL PHASE I TRIALS. 172
5-Aza-2'-Deoxycitidine induces growth-inhibition and up-regulation of epidermal-growth factor receptor on human epithelial cancer-cells 167
A phase II study of biweekly oxaliplatin plus infusional 5-fluorouracil and folinic acid (FLFOX-4) as first-line treatment of advanced gastric cancer patients. 166
Anti-sense oligonucleotides directed against EGF-related growth factors enhance anti-proliferative effect of conventional anti-tumor drugs in human colon-cancer cells. 163
Procoagulant and fibrinolytic activity of human ovarian carcinoma cells in culture. 162
Activity and safety of pegylated liposomal doxorubicin, 5-fluorouracil and folinic acid in inoperable hepatocellular carcinoma: a phase II study. 157
8-Cl-cAMP in differentiation therapy: The reversal and suppression of malignancy targeting the intracellular transducing proteins of cAMP. 157
Regulation of the expression of Fc-epsilon-R in the human monocyte like cell line U937 by TPA and IgE. 156
Reversal of adriamycin resistance by recombinant alpha-interferon in multidrug-resistant human colon carcinoma LoVo-doxorubicin cells. 155
Enhancement of antitumor activity of ionizing radiation by combined treatment with the selective EGFR-tyrosine kinase inhibitor ZD1839 (‘Iressa’) 155
Adjuvant Treatment for Locally Advanced Rectal Cancer Patients After Preoperative Chemoradiotherapy: When, and for Whom? 155
8-Chloro-cAMP enhances the growth inhibitory effect of cytotoxic drugs in human colon cancer cells 153
NM23 gene expression correlates with cell growth rate and S-phase. 152
Modulation of thymidilate synthase and p53 expression by HDAC inhibitor vorinostat resulted in synergistic antitumor effect in combination with 5FU or raltitrexed. 152
Poly(ADPR)polymerase-1 signalling of the DNA damage induced by DNA topoisomerase I poison in D54p53wt and U251p53mut glioblastoma cell lines. 152
Tumori Eredo-Familiari 152
A phase II study of biweekly oxaliplatin plus infusional 5-fluorouracil and folinic acid (FOLFOX-4) as first-line treatment of advanced gastric cancer patients. 151
Down-regulation of RI alpha subunit of cAMP-dependent protein kinase induces growth inhibition of human mammary epithelial cells transformed by c-Ha-ras and c-erbB-2 proto-oncogenes. 150
TSH-regulated growth and cell cycle distribution of thyroid cells involve type I isozyme of cAMP-dependent protein kinase 149
Recombinant IFN-alfa 2b treatment activates poly (ADPR) polymerase-1 (PARP-1) in KB cancer cells. 148
Abstract 4017: Anti-tumor activity of a BRAF inhibitor and IFNα combination in BRAF mutant melanoma 148
Synergistic anti-tumour effect of raltitrexed and 5-fluorouracil plus folinic acid combination in human cancer cells. 147
Retinoic acid induces neuronal differentiation of embryonal carcinoma cells by reducing proteasome-dependent proteolysis of the cyclin-dependent inhibitor p27. 147
Antitumor activity of BRAF inhibitor and IFN×alpha; Combination in BRAF-mutant melanoma 144
A phase I/II trial of gefitinib and radiotherapy in patients with locally advanced inoperable squamous cell carcinoma of the head and neck. 142
Sequence-dependent, synergistic antiproliferative and proapoptotic effects of the combination of cytotoxic drugs and enzastaurin, a protein kinase C beta inhibitor, in non-small cell lung cancer cells. 141
Analysis of Differential miRNA Expression in Primary Tumor and Stroma of Colorectal Cancer Patients 139
A specific miRNA signature correlates with complete pathological response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer 138
Enhanced Expression of CD47 Is Associated With Off-Target Resistance to Tyrosine Kinase Inhibitor Gefitinib in NSCLC 138
Non lymphomatous clonal B-Cell populations in enlarged lymph nodes in acquired immunodeficiency syndrome. 138
A Specific miRNA Signature Correlates with Complete Pathological Response to Neoadjuvant Chemoradiotherapy in Locally Advanced Rectal Cancer. 137
Oral antisense targeting protein kinase A type I causes antitumor and apoptotic effect in human cancer cells in vitro and in vivo and has cooperative activity in combination with antisense bcl-2. 137
Loss of thyrotropin regulation and trasforming growth factor beta-induced growth arrest in erbB-2 overexpressing rat thyroid cells. 136
Expression of teratocarcinoma-derived growth factor-1 (TDGF-1) in testis germ cell tumors and its effects on growth and differentiation of embryonal carcinoma cell line NTERA2/D1. 136
Type-I isoform of PKA is involved in the control of cell proliferation and oncogene transformation of human mammary epithelial cells.Therapeutic implications 136
Altre Neoplasie 135
DNA-flow cytometry (ploidy and S-phase fraction) as prognostic factor in a retrospectine series of 515 primary breast cancer. 134
Cooperative inhibitory effect of novel mixed backbone oligonucleotide targeting Protein Kinase A in combination with docetaxel and anti-EGFR-Receptor antibody on human breast cancer cell growth. 134
Growth inhibition of tumor cells by epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 is associated with upregulation of p27 and p21 cyclin-dependent kinase inhibitors. 134
The expression of proliferating cell nuclear antigen in paraffin sections of peripheral, node-negative non-small cell lung cancer. 133
Farsi promotori di salute: “Safe Sun Coast” 132
DNA index of ovarian carcinomas from 56 different patients: in vivo, in vitro studies. 131
Predictive factors of response to neoadjuvant chemoradiotherapy in rectal cancer patirnts. 131
Abstract 3703: PDGFRα up-regulation mediated by Sonic Hedgehog Pathway activation leads to BRAF inhibitor resistance in melanoma cells with BRAF mutation 131
Synergistic anti-proliferative and pro-apoptotic activity of combined therapy with bortezomib, a proteasome inhibitor, with anti-epidermal growth factor receptor (EGFR) drugs in human cancer cells. 130
TGFb inhibits rat thyroid cell proliferation without alterations in the expression of THS-induced cell cycle-related genes. Vol :pp , 130
Neo-adjuvant treatment of rectal cancer with capecitabine and oxaliplatin in combination with radiotherapy: a phase II study. 130
rs10204525 binding to miR-4717-3p modulates PD-1 expression and predicts the development of immune-related adverse events in advanced cancer patients treated with anti-PD-1/PD-L1 therapy 129
Reduction of RIAlpha subunit of cAMP-dependent Protein-Kinase expression induces growth-inhibition of human mammary epithelial-cells transformed by TGF-Alha, C-HA-RAS, and C-ErbB2 genes. 129
Critical role of both p27kip1 and p21cip1/waf1 in the antiproliferative effect of ZD1839 (‘Iressa’), an epidermal growth factor receptor tyrosine kinase inhibitor, in head and neck squamous carcinoma cells. 128
Inhibition of NF-kB activity potentiates ionizing radiation and cisplatin induced cell killing of anaplastic thyroid carcinoma cells AACR Meeting Abstracts, Apr 2006; 2006: 1038. 128
Cell growth-inhibition and cell cycle perturbations induced by a new synthetic iminoquinone, 5H-pyridophenoxazin-5-one, in human breast carcinoma cell lines. 127
Theophylline-induced apoptosis is paralleled by protein kinase A-dependent tissue transglutaminase activation in cancer cells. 127
Growth arrest, apoptosis and potentiation of 5-fluorouracil and Raltitrexed cytotoxic effect induced by histone deacetylase inhibitor SAHA in colorectal cancer cells. 126
PRECLINICAL AND PHASE I STUDY OF OXALIPLATIN AND TOPOTECAN IN COMBINATION IN HUMAN CANCER. 126
Synergistic inhibition of growth and induction of apoptosis by 8-chloro-cAMP and paclitaxel or cisplatin in human cancer cells. 124
TESI DI DOTTORATO: Hereditary and familial breast and ovarian cancer: spectrum of related tumors. CANDIDATO: M.Pensabene. RELATORE: S.Pepe 124
Suppression of malignancy targeting the intracellular signal transducing proteins of cAMP: the use of site selective cAMP analogs, antisense strategy, and gene-transfer. 124
Bevacizumab maintenance in metastatic colorectal cancer: How long?. 124
Enzastaurin inhibits tumors sensitive and resistant to anti-EGFR drugs 123
P53 expression in non-small-cell lung-cancer. Clinical and biological correlations. 123
Phase I-II study of sequential combination of XELOX and bevacizumab plus erlotinib (XELOX-TARAV) in first line colorectal patients:Run in phase I part 123
Measurement of neovascularization is an independent prognosticator of survival in node-negative breast cancer patients with long-lerm follow-up. 121
POLY(ADENOSINE DIPHOSPHATE-RIBOSE) POLYMERASE 1 EXPRESSION IN MALIGNANT MELANOMAS FROM PHOTOEXPOSED AREAS OF THE HEAD AND NECK REGION. 121
Blast cells DNA content in childhood leukemias. 120
Cell ploidy in 19 Wilms tumors by flow-cytometry of cell suspensions prepared from paraffina embedded sections. 120
IgE receptors. 119
Cooperative effect of 8-Cl-cAMP and rhGM-CSF on the differentiation of HL-60 human leukemia-cells. 119
Overexpression of the RIα subunit of Protein Kinase A confers hypersensitivity to topoisomerase II inhibitors and 8-Chloro-cyclic Adenosine 3′,5′-Monophosphate in chinese hamster ovary cells. 118
The cancer spectrum related to hereditary and familial breast and ovarian cancers 117
Predictive factors of complete response to neoadjuvant chemoradiotherapy in patients with rectal cancer. 115
Interferon-alpha induces apoptosis in human KB cells through a stress-dependent mitogen activated protein kinase pathway death is antagonized by epidermal growth factor. 115
EGF activates an inducible survival response via the RAS -> Erk-1/2 pathway to counteract interferon-alfa-mediated apoptosis in epidermoid cancer cells. 115
Antisense-protein kinase A: a single-gene-based therapeutic approach. 115
The farnesyltransferase inhibitor R115777 (Zanestra) synergizes with ionizing radiation in inducing cell cycle perturbation and growth inhibition of human epidermoid head and neck cancer cells. 115
Synerglstic antltumor effect by novel modified oligonucleotides targeting PKAI combined with cytotoxic drugs or monoclonal antibodies. 115
Multidisciplinary Approach to Patient with Malignant Melanoma 115
21st ISoP Annual Meeting “A New Era of Pharmacovigilance: Challenges and Opportunities” 20–23 September 2022 Verona, Italy 114
Epidermal growth factor (EGFR) and Transferrin (TRFR) receptor upregulation is induced by arabinoside cytosine (ARA-C) on human tumor cells. 114
EGF-R tyrosyne kinase as new target in melanoma treatment; Synergistic effect of IFN alpha in combination with ZD1839 )Iressa) , an EGFR tyrosine kinase inhibitor. 114
Molecules and mechanisms to overcome oxidative stress inducing cardiovascular disease in cancer patients 114
Two mutations of BRCA2 gene at exon and splicing site in a woman who underwent oncogenetic counseling 113
Totale 16.147
Categoria #
all - tutte 73.180
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 73.180


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021491 0 0 0 0 0 0 0 0 0 0 168 323
2021/20221.181 4 0 3 35 30 39 15 54 189 161 141 510
2022/20231.923 190 91 53 246 271 420 2 169 357 10 74 40
2023/20241.135 80 136 66 27 67 142 276 61 28 39 47 166
2024/20252.370 78 33 52 94 147 364 392 242 317 102 243 306
2025/20268.793 572 1.670 1.421 380 953 565 1.400 278 593 822 139 0
Totale 25.021