UniSa - IRIS Institutional Research Information System

PEPE, Stefano
 Distribuzione geografica
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Continente #
NA - Nord America 10.457
EU - Europa 2.812
AS - Asia 2.318
SA - Sud America 332
Continente sconosciuto - Info sul continente non disponibili 31
AF - Africa 27
OC - Oceania 7
Totale 15.984
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Nazione #
US - Stati Uniti d'America 10.414
CN - Cina 841
UA - Ucraina 762
SG - Singapore 702
IT - Italia 569
DE - Germania 413
RU - Federazione Russa 325
BR - Brasile 309
VN - Vietnam 291
IE - Irlanda 265
FI - Finlandia 231
KR - Corea 172
TR - Turchia 152
SE - Svezia 88
IN - India 49
HK - Hong Kong 43
AT - Austria 37
GB - Regno Unito 35
EU - Europa 30
CA - Canada 28
CZ - Repubblica Ceca 22
FR - Francia 19
NL - Olanda 12
IQ - Iraq 10
JO - Giordania 10
PL - Polonia 10
JP - Giappone 9
ES - Italia 8
MX - Messico 8
AR - Argentina 7
MA - Marocco 7
DZ - Algeria 6
IL - Israele 6
PK - Pakistan 6
BD - Bangladesh 5
TN - Tunisia 5
EC - Ecuador 4
AL - Albania 3
AU - Australia 3
BG - Bulgaria 3
CO - Colombia 3
CR - Costa Rica 3
ID - Indonesia 3
KG - Kirghizistan 3
NP - Nepal 3
NZ - Nuova Zelanda 3
UZ - Uzbekistan 3
VE - Venezuela 3
ZA - Sudafrica 3
CL - Cile 2
EG - Egitto 2
GR - Grecia 2
IR - Iran 2
JM - Giamaica 2
LT - Lituania 2
MY - Malesia 2
NO - Norvegia 2
PE - Perù 2
RO - Romania 2
AE - Emirati Arabi Uniti 1
AZ - Azerbaigian 1
BH - Bahrain 1
BY - Bielorussia 1
GT - Guatemala 1
KE - Kenya 1
KI - Kiribati 1
LB - Libano 1
MK - Macedonia 1
MM - Myanmar 1
MU - Mauritius 1
NG - Nigeria 1
PA - Panama 1
PY - Paraguay 1
SA - Arabia Saudita 1
SN - Senegal 1
UY - Uruguay 1
XK - ???statistics.table.value.countryCode.XK??? 1
Totale 15.984
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Città #
Ann Arbor 2.852
Woodbridge 1.235
Wilmington 1.081
Jacksonville 921
Houston 904
Chandler 793
Princeton 663
Beijing 297
Dong Ket 290
Dublin 262
Ashburn 247
Singapore 217
Andover 172
Munich 157
Nanjing 150
Izmir 145
Pellezzano 125
Boardman 124
Mestre 107
Moscow 87
Düsseldorf 67
Fairfield 55
Naples 51
Nanchang 50
Shenyang 46
Hebei 44
Hong Kong 43
Salerno 43
Helsinki 42
Jiaxing 37
Changsha 35
Washington 35
Dallas 31
Pune 31
Los Angeles 30
Nuremberg 28
Falls Church 26
Tianjin 26
Turku 26
New York 24
The Dalles 23
Vienna 23
Norwalk 22
São Paulo 21
Brno 17
Venezia 17
Cambridge 16
Redwood City 15
Seattle 15
San Francisco 14
Columbus 13
Santa Clara 13
Chicago 12
Guangzhou 12
Ottawa 12
Paris 12
San Diego 12
London 11
Amman 10
Brasília 10
Brooklyn 10
Milan 10
Rome 10
Tappahannock 10
Warsaw 10
Shanghai 9
Dearborn 8
Indiana 7
Montreal 7
Napoli 7
Rio de Janeiro 7
Sarno 7
Belo Horizonte 6
Castellammare di Stabia 6
Chennai 6
Jinan 6
Jyväskylä 6
Tokyo 6
Amsterdam 5
Baghdad 5
Bologna 5
Fisciano 5
Hangzhou 5
Mercato San Severino 5
Mountain View 5
Porto Alegre 5
Rutigliano 5
Shijiazhuang 5
Zhengzhou 5
Contagem 4
Guarulhos 4
Lappeenranta 4
Ningbo 4
Phoenix 4
Redmond 4
Stockholm 4
Yellow Springs 4
Yiwu 4
Angri 3
Ashdod 3
Totale 12.134
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Nome #
Differential sensitivity to non-MHC-restricted rIL-2 activated lymphocyte killing of human mammary epithelial MCF-10A cells overexpressing oncogenes or PKA subunits. 338
The role of immunotherapy in solid tumors: report from the Campania Society of Oncology Immunotherapy (SCITO) meeting, Naples 2014. 253
Abstract 3132: Single nucleotide polymorphisms (SNPs) in PD-L1 as predictive biomarkers for checkpoint inhibitor based-immunotherapy in caucasian patients with advanced NSCLC 227
Phase I clinical study with 8-Chloro-cAMP and evaluation of immunological effects in cancer patients. 153
Nuclear DNA content-derived parameters correlated with heterogeneous expression of p53 and bcl-2 proteins in clear cell renal carcinomas. 151
Procoagulant and fibrinolytic activity of human ovarian carcinoma cells in culture. 134
Anti-sense oligonucleotides directed against EGF-related growth factors enhance anti-proliferative effect of conventional anti-tumor drugs in human colon-cancer cells. 132
Modulation of thymidilate synthase and p53 expression by HDAC inhibitor vorinostat resulted in synergistic antitumor effect in combination with 5FU or raltitrexed. 131
Reversal of adriamycin resistance by recombinant alpha-interferon in multidrug-resistant human colon carcinoma LoVo-doxorubicin cells. 129
Tumori Eredo-Familiari 129
Recombinant IFN-alfa 2b treatment activates poly (ADPR) polymerase-1 (PARP-1) in KB cancer cells. 127
NM23 gene expression correlates with cell growth rate and S-phase. 126
ADDITION OF ERLOTINIB TO FLUROPYRIMIDINE-OXALIPLATIN-BASED CHEMOTHERAPY WITH OR WITHOUT BEVACIZUMAB: TWO SEQUENTIAL PHASE I TRIALS. 126
A phase I-II trial of gefitinib (IRESSA) and radiotherapy in patients with locally advanced inoperable squamous cell carcinoma of the head and neck (SCCHN) 126
Enhancement of antitumor activity of ionizing radiation by combined treatment with the selective EGFR-tyrosine kinase inhibitor ZD1839 (‘Iressa’) 125
5-Aza-2'-Deoxycitidine induces growth-inhibition and up-regulation of epidermal-growth factor receptor on human epithelial cancer-cells 125
Regulation of the expression of Fc-epsilon-R in the human monocyte like cell line U937 by TPA and IgE. 124
Epidermal growth factor receptor (EGFr) expression in non-small cell lung carcinomas correlates with metastatic involvement of hilar and mediastinal lymph nodes in the squamous subtype 123
Additive effects of c-erbB-2, c-Ha-ras, and transforming growth factor-a genes on in vitro transformation of human mammary epithelial cells. 123
Retinoic acid induces neuronal differentiation of embryonal carcinoma cells by reducing proteasome-dependent proteolysis of the cyclin-dependent inhibitor p27. 121
A phase II study of biweekly oxaliplatin plus infusional 5-fluorouracil and folinic acid (FLFOX-4) as first-line treatment of advanced gastric cancer patients. 118
Synergistic anti-tumour effect of raltitrexed and 5-fluorouracil plus folinic acid combination in human cancer cells. 116
Adjuvant treatment of diabetic foot 116
Down-regulation of RI alpha subunit of cAMP-dependent protein kinase induces growth inhibition of human mammary epithelial cells transformed by c-Ha-ras and c-erbB-2 proto-oncogenes. 116
Analysis of Differential miRNA Expression in Primary Tumor and Stroma of Colorectal Cancer Patients 115
TSH-regulated growth and cell cycle distribution of thyroid cells involve type I isozyme of cAMP-dependent protein kinase 114
8-Cl-cAMP in differentiation therapy: The reversal and suppression of malignancy targeting the intracellular transducing proteins of cAMP. 114
Cooperative inhibitory effect of novel mixed backbone oligonucleotide targeting Protein Kinase A in combination with docetaxel and anti-EGFR-Receptor antibody on human breast cancer cell growth. 113
Loss of thyrotropin regulation and trasforming growth factor beta-induced growth arrest in erbB-2 overexpressing rat thyroid cells. 112
Reduction of RIAlpha subunit of cAMP-dependent Protein-Kinase expression induces growth-inhibition of human mammary epithelial-cells transformed by TGF-Alha, C-HA-RAS, and C-ErbB2 genes. 112
Sequence-dependent, synergistic antiproliferative and proapoptotic effects of the combination of cytotoxic drugs and enzastaurin, a protein kinase C beta inhibitor, in non-small cell lung cancer cells. 111
Activity and safety of pegylated liposomal doxorubicin, 5-fluorouracil and folinic acid in inoperable hepatocellular carcinoma: a phase II study. 111
Antitumor activity of BRAF inhibitor and IFN×alpha; Combination in BRAF-mutant melanoma 111
Oral antisense targeting protein kinase A type I causes antitumor and apoptotic effect in human cancer cells in vitro and in vivo and has cooperative activity in combination with antisense bcl-2. 110
DNA index of ovarian carcinomas from 56 different patients: in vivo, in vitro studies. 109
TGFb inhibits rat thyroid cell proliferation without alterations in the expression of THS-induced cell cycle-related genes. Vol :pp , 108
Adjuvant Treatment for Locally Advanced Rectal Cancer Patients After Preoperative Chemoradiotherapy: When, and for Whom? 107
DNA-flow cytometry (ploidy and S-phase fraction) as prognostic factor in a retrospectine series of 515 primary breast cancer. 106
Growth inhibition of tumor cells by epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 is associated with upregulation of p27 and p21 cyclin-dependent kinase inhibitors. 106
Type-I isoform of PKA is involved in the control of cell proliferation and oncogene transformation of human mammary epithelial cells.Therapeutic implications 105
Cell growth-inhibition and cell cycle perturbations induced by a new synthetic iminoquinone, 5H-pyridophenoxazin-5-one, in human breast carcinoma cell lines. 105
The expression of proliferating cell nuclear antigen in paraffin sections of peripheral, node-negative non-small cell lung cancer. 104
Inhibition of NF-kB activity potentiates ionizing radiation and cisplatin induced cell killing of anaplastic thyroid carcinoma cells AACR Meeting Abstracts, Apr 2006; 2006: 1038. 104
Synergistic anti-proliferative and pro-apoptotic activity of combined therapy with bortezomib, a proteasome inhibitor, with anti-epidermal growth factor receptor (EGFR) drugs in human cancer cells. 102
Critical role of both p27kip1 and p21cip1/waf1 in the antiproliferative effect of ZD1839 (‘Iressa’), an epidermal growth factor receptor tyrosine kinase inhibitor, in head and neck squamous carcinoma cells. 102
Predictive factors of response to neoadjuvant chemoradiotherapy in rectal cancer patirnts. 102
POLY(ADENOSINE DIPHOSPHATE-RIBOSE) POLYMERASE 1 EXPRESSION IN MALIGNANT MELANOMAS FROM PHOTOEXPOSED AREAS OF THE HEAD AND NECK REGION. 101
PRECLINICAL AND PHASE I STUDY OF OXALIPLATIN AND TOPOTECAN IN COMBINATION IN HUMAN CANCER. 101
A phase I/II trial of gefitinib and radiotherapy in patients with locally advanced inoperable squamous cell carcinoma of the head and neck. 99
Enzastaurin inhibits tumors sensitive and resistant to anti-EGFR drugs 99
Blast cells DNA content in childhood leukemias. 98
Growth arrest, apoptosis and potentiation of 5-fluorouracil and Raltitrexed cytotoxic effect induced by histone deacetylase inhibitor SAHA in colorectal cancer cells. 98
IgE receptors. 98
8-Chloro-cAMP enhances the growth inhibitory effect of cytotoxic drugs in human colon cancer cells 97
Suppression of malignancy targeting the intracellular signal transducing proteins of cAMP: the use of site selective cAMP analogs, antisense strategy, and gene-transfer. 97
A phase II study of biweekly oxaliplatin plus infusional 5-fluorouracil and folinic acid (FOLFOX-4) as first-line treatment of advanced gastric cancer patients. 96
The farnesyltransferase inhibitor R115777 (Zanestra) synergizes with ionizing radiation in inducing cell cycle perturbation and growth inhibition of human epidermoid head and neck cancer cells. 96
Cell ploidy in 19 Wilms tumors by flow-cytometry of cell suspensions prepared from paraffina embedded sections. 96
Overexpression of wild-type p53 ovverrides the mitogenic effect of the RIa subunit of protein kinase A in human breast cells. 95
EGF-R tyrosyne kinase as new target in melanoma treatment; Synergistic effect of IFN alpha in combination with ZD1839 )Iressa) , an EGFR tyrosine kinase inhibitor. 94
Synergistic inhibition of growth and induction of apoptosis by 8-chloro-cAMP and paclitaxel or cisplatin in human cancer cells. 92
Epidermal growth factor (EGFR) and Transferrin (TRFR) receptor upregulation is induced by arabinoside cytosine (ARA-C) on human tumor cells. 92
EPIGENETIC FACTORS IN HEREDITARY BREAST CANCER 92
P53 expression in non-small-cell lung-cancer. Clinical and biological correlations. 92
Synerglstic antltumor effect by novel modified oligonucleotides targeting PKAI combined with cytotoxic drugs or monoclonal antibodies. 92
Multidisciplinary Approach to Patient with Malignant Melanoma 92
Bevacizumab maintenance in metastatic colorectal cancer: How long?. 91
Abstract 4017: Anti-tumor activity of a BRAF inhibitor and IFNα combination in BRAF mutant melanoma 90
Antisense-protein kinase A: a single-gene-based therapeutic approach. 89
Altre Neoplasie 89
Phase I-II study of sequential combination of XELOX and bevacizumab plus erlotinib (XELOX-TARAV) in first line colorectal patients:Run in phase I part 89
Antisense DNA-targeting protein kinase A-RIA subunit: a novel approach to cancer treatment. 88
Antitumor activity of sequential treatment with topotecan and anti-epidermal growth factor receptor monoclonal antibody C225. 88
Predictive factors of complete response to neoadjuvant chemoradiotherapy in patients with rectal cancer. 88
Key role of the cyclin-dependent kinase inhibitor p27kip1 for embryonal carcinoma cell survival and differentiation. 88
TESI DI DOTTORATO: Hereditary and familial breast and ovarian cancer: spectrum of related tumors. CANDIDATO: M.Pensabene. RELATORE: S.Pepe 88
Cooperative effect of 8-Cl-cAMP and rhGM-CSF on the differentiation of HL-60 human leukemia-cells. 88
REPLY TO BRCA2 SPLICE SITE MUTATIONS IN ITALIAN BREAST/OVARIAN CANCER FAMILY. 88
Radioresistance in head and neck squamous cell carcinoma: Biological bases and therapeutic implications. 88
Farsi promotori di salute: “Safe Sun Coast” 88
p53 alterations in non-small cell lung cancers correlate with metastatic involvement of hilar and mediastinal lymph nodes. 87
EGF activates an inducible survival response via the RAS -> Erk-1/2 pathway to counteract interferon-alfa-mediated apoptosis in epidermoid cancer cells. 87
Markers of cell-proliferation (p21, PCNA, S-Phase) as prognostic factors in papillary thyroid carcinoma. 87
Synergistic antitumor activity of epidermal growth factor receptor tyrosine kinase inhibitor gefitinib and IFN-A in head and neck cancer cells in vitro and in vivo 86
Interferon-alpha induces apoptosis in human KB cells through a stress-dependent mitogen activated protein kinase pathway death is antagonized by epidermal growth factor. 86
Measurement of neovascularization is an independent prognosticator of survival in node-negative breast cancer patients with long-lerm follow-up. 86
Flow-cytometric detection of the RI-alpha subunit of Type-I cAMP-dependent protein-kinase in human-cells 86
Antitumor Agents. 5. Synthesis, structure−activity relationships, and biological evaluation of dimethyl-5H-pyridophenoxazin-5-ones, tetrahydro-5H-benzopyridophenoxazin-5-ones, and 5H-benzopyridophenoxazin-5-ones with potent antiproliferative activity. 86
Counteracting resistance to treatments in solid tumors. 86
Phorbol-12-myristate-13-acetate (PMA) induces resistance of human melanoma cells to NK and LAK-mediated cytotoxicity. 85
Introducing an autophosphorylation site mutation in the RII-beta regulatory subunit of cAMP-dependent Protein-Kinase abolishes the RII-beta -mediated regulatory function. 85
Overexpression of the RIα subunit of Protein Kinase A confers hypersensitivity to topoisomerase II inhibitors and 8-Chloro-cyclic Adenosine 3′,5′-Monophosphate in chinese hamster ovary cells. 85
Synergistic antitumor activity of the combination of the multi-targetes tyrosine kinase inhibitor sorafenib and of EGFR inhibitors in human colon and lung cancer cell lines. 85
Theophylline-induced apoptosis is paralleled by protein kinase A-dependent tissue transglutaminase activation in cancer cells. 85
Diagnostic utility of BRAFV600E mutation testing in thyroid nodules in elderly patients 84
Quality control for the evaluation of the S-phase fraction by flow cytometry: a multicentric study. 84
Capecitabine plus weekly oxaliplatin in gastrointestinal tumors: a phase I study. 84
Retroviral vector-mediated overexpression of the RIIbeta subunit of the cAMP-dependent protein kinase induces differentiation in human leukemia cells and reverts the transformed phenotype of mouse fibroblasts. 84
Twenty-year results of the Naples GUN randomized trial: predictive factors of adjuvant tamoxifen efficacy in early breast cancer. 84
Unhydrolyzable analogs of Adenosine 3'/5'-monophosphate demonstrating growth-inhibition and differentiation in human cancer-cells. 84
Totale 10.735
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Categoria #
all - tutte 49.543
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 49.543
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/20211.355 13 151 155 14 164 30 171 11 153 2 168 323
2021/20221.181 4 0 3 35 30 39 15 54 189 161 141 510
2022/20231.923 190 91 53 246 271 420 2 169 357 10 74 40
2023/20241.135 80 136 66 27 67 142 276 61 28 39 47 166
2024/20252.370 78 33 52 94 147 364 392 242 317 102 243 306
2025/202629 29 0 0 0 0 0 0 0 0 0 0 0
Totale 16.257