UniSa - IRIS Institutional Research Information System

PEPE, Stefano
 Distribuzione geografica
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Continente #
NA - Nord America 10.610
AS - Asia 3.310
EU - Europa 2.863
SA - Sud America 368
Continente sconosciuto - Info sul continente non disponibili 31
AF - Africa 29
OC - Oceania 9
Totale 17.220
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Nazione #
US - Stati Uniti d'America 10.550
HK - Hong Kong 963
CN - Cina 843
UA - Ucraina 763
SG - Singapore 742
IT - Italia 570
DE - Germania 434
BR - Brasile 344
RU - Federazione Russa 325
VN - Vietnam 296
IE - Irlanda 265
FI - Finlandia 231
KR - Corea 172
TR - Turchia 152
SE - Svezia 91
IN - India 59
GB - Regno Unito 48
AT - Austria 41
CA - Canada 38
EU - Europa 30
CZ - Repubblica Ceca 22
FR - Francia 19
IQ - Iraq 13
NL - Olanda 13
ES - Italia 12
MX - Messico 12
PL - Polonia 12
JO - Giordania 10
JP - Giappone 10
BD - Bangladesh 9
AR - Argentina 7
MA - Marocco 7
UZ - Uzbekistan 7
DZ - Algeria 6
IL - Israele 6
PK - Pakistan 6
AU - Australia 5
CR - Costa Rica 5
TN - Tunisia 5
CO - Colombia 4
EC - Ecuador 4
ZA - Sudafrica 4
AE - Emirati Arabi Uniti 3
AL - Albania 3
BG - Bulgaria 3
ID - Indonesia 3
KG - Kirghizistan 3
NP - Nepal 3
NZ - Nuova Zelanda 3
RO - Romania 3
VE - Venezuela 3
CL - Cile 2
EG - Egitto 2
GR - Grecia 2
IR - Iran 2
JM - Giamaica 2
LT - Lituania 2
MY - Malesia 2
NO - Norvegia 2
PE - Perù 2
SA - Arabia Saudita 2
SN - Senegal 2
AZ - Azerbaigian 1
BH - Bahrain 1
BY - Bielorussia 1
GT - Guatemala 1
KE - Kenya 1
KI - Kiribati 1
LB - Libano 1
MK - Macedonia 1
MM - Myanmar 1
MU - Mauritius 1
NG - Nigeria 1
PA - Panama 1
PY - Paraguay 1
TT - Trinidad e Tobago 1
UY - Uruguay 1
XK - ???statistics.table.value.countryCode.XK??? 1
Totale 17.220
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Città #
Ann Arbor 2.852
Woodbridge 1.235
Wilmington 1.081
Hong Kong 963
Jacksonville 921
Houston 904
Chandler 793
Princeton 663
Beijing 299
Dong Ket 290
Ashburn 262
Dublin 262
Singapore 255
Munich 176
Andover 172
Nanjing 150
Izmir 145
Pellezzano 125
Boardman 124
Mestre 107
Moscow 87
Düsseldorf 67
Fairfield 55
Naples 51
Nanchang 50
Shenyang 46
Hebei 44
Salerno 43
Helsinki 42
Los Angeles 40
Jiaxing 37
Changsha 35
Dallas 35
Washington 35
New York 34
Pune 31
Nuremberg 29
Falls Church 26
Tianjin 26
Turku 26
São Paulo 25
Columbus 24
Vienna 24
The Dalles 23
Norwalk 22
Brooklyn 21
Santa Clara 20
Seattle 20
Brno 17
Venezia 17
Cambridge 16
Chicago 16
San Francisco 16
London 15
Redwood City 15
Guangzhou 12
Ottawa 12
Paris 12
San Diego 12
Warsaw 12
Montreal 11
Amman 10
Brasília 10
Milan 10
Rome 10
Tappahannock 10
Chennai 9
Shanghai 9
Dearborn 8
Baghdad 7
Charlotte 7
Indiana 7
Napoli 7
Rio de Janeiro 7
Sarno 7
Stockholm 7
Tashkent 7
Tokyo 7
Belo Horizonte 6
Boston 6
Castellammare di Stabia 6
Jinan 6
Jyväskylä 6
Porto Alegre 6
Amsterdam 5
Atlanta 5
Bologna 5
Council Bluffs 5
Fisciano 5
Hangzhou 5
Mercato San Severino 5
Mountain View 5
Rutigliano 5
San Jose 5
Shijiazhuang 5
Zhengzhou 5
Campinas 4
Contagem 4
Fort Worth 4
Guarulhos 4
Totale 13.231
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Nome #
Bispecific Antibodies: A Novel Approach for the Treatment of Solid Tumors 391
Differential sensitivity to non-MHC-restricted rIL-2 activated lymphocyte killing of human mammary epithelial MCF-10A cells overexpressing oncogenes or PKA subunits. 339
Epidermal growth factor receptor (EGFr) expression in non-small cell lung carcinomas correlates with metastatic involvement of hilar and mediastinal lymph nodes in the squamous subtype 287
The role of immunotherapy in solid tumors: report from the Campania Society of Oncology Immunotherapy (SCITO) meeting, Naples 2014. 253
Abstract 3132: Single nucleotide polymorphisms (SNPs) in PD-L1 as predictive biomarkers for checkpoint inhibitor based-immunotherapy in caucasian patients with advanced NSCLC 229
Radioresistance in head and neck squamous cell carcinoma: Biological bases and therapeutic implications. 175
Overexpression of wild-type p53 ovverrides the mitogenic effect of the RIa subunit of protein kinase A in human breast cells. 170
Phase I clinical study with 8-Chloro-cAMP and evaluation of immunological effects in cancer patients. 155
Nuclear DNA content-derived parameters correlated with heterogeneous expression of p53 and bcl-2 proteins in clear cell renal carcinomas. 152
Measurement of neovascularization is an independent prognosticator of survival in node-negative breast cancer patients with long-term follow-up 143
Anti-sense oligonucleotides directed against EGF-related growth factors enhance anti-proliferative effect of conventional anti-tumor drugs in human colon-cancer cells. 135
Procoagulant and fibrinolytic activity of human ovarian carcinoma cells in culture. 135
Reversal of adriamycin resistance by recombinant alpha-interferon in multidrug-resistant human colon carcinoma LoVo-doxorubicin cells. 132
Modulation of thymidilate synthase and p53 expression by HDAC inhibitor vorinostat resulted in synergistic antitumor effect in combination with 5FU or raltitrexed. 132
Tumori Eredo-Familiari 130
rs822336 as a predictive biomarker for anti-PD-1/PD-L1 immunotherapy in advanced NSCLC: Unraveling molecular mechanisms 129
Recombinant IFN-alfa 2b treatment activates poly (ADPR) polymerase-1 (PARP-1) in KB cancer cells. 129
Enhancement of antitumor activity of ionizing radiation by combined treatment with the selective EGFR-tyrosine kinase inhibitor ZD1839 (‘Iressa’) 128
ADDITION OF ERLOTINIB TO FLUROPYRIMIDINE-OXALIPLATIN-BASED CHEMOTHERAPY WITH OR WITHOUT BEVACIZUMAB: TWO SEQUENTIAL PHASE I TRIALS. 128
5-Aza-2'-Deoxycitidine induces growth-inhibition and up-regulation of epidermal-growth factor receptor on human epithelial cancer-cells 128
A phase I-II trial of gefitinib (IRESSA) and radiotherapy in patients with locally advanced inoperable squamous cell carcinoma of the head and neck (SCCHN) 128
NM23 gene expression correlates with cell growth rate and S-phase. 127
Retinoic acid induces neuronal differentiation of embryonal carcinoma cells by reducing proteasome-dependent proteolysis of the cyclin-dependent inhibitor p27. 126
Additive effects of c-erbB-2, c-Ha-ras, and transforming growth factor-a genes on in vitro transformation of human mammary epithelial cells. 126
Regulation of the expression of Fc-epsilon-R in the human monocyte like cell line U937 by TPA and IgE. 125
A phase II study of biweekly oxaliplatin plus infusional 5-fluorouracil and folinic acid (FLFOX-4) as first-line treatment of advanced gastric cancer patients. 120
Adjuvant treatment of diabetic foot 119
TSH-regulated growth and cell cycle distribution of thyroid cells involve type I isozyme of cAMP-dependent protein kinase 118
Synergistic anti-tumour effect of raltitrexed and 5-fluorouracil plus folinic acid combination in human cancer cells. 117
Down-regulation of RI alpha subunit of cAMP-dependent protein kinase induces growth inhibition of human mammary epithelial cells transformed by c-Ha-ras and c-erbB-2 proto-oncogenes. 117
8-Cl-cAMP in differentiation therapy: The reversal and suppression of malignancy targeting the intracellular transducing proteins of cAMP. 115
Analysis of Differential miRNA Expression in Primary Tumor and Stroma of Colorectal Cancer Patients 115
Sequence-dependent, synergistic antiproliferative and proapoptotic effects of the combination of cytotoxic drugs and enzastaurin, a protein kinase C beta inhibitor, in non-small cell lung cancer cells. 114
Cooperative inhibitory effect of novel mixed backbone oligonucleotide targeting Protein Kinase A in combination with docetaxel and anti-EGFR-Receptor antibody on human breast cancer cell growth. 114
Loss of thyrotropin regulation and trasforming growth factor beta-induced growth arrest in erbB-2 overexpressing rat thyroid cells. 113
Activity and safety of pegylated liposomal doxorubicin, 5-fluorouracil and folinic acid in inoperable hepatocellular carcinoma: a phase II study. 113
Antitumor activity of BRAF inhibitor and IFN×alpha; Combination in BRAF-mutant melanoma 113
Reduction of RIAlpha subunit of cAMP-dependent Protein-Kinase expression induces growth-inhibition of human mammary epithelial-cells transformed by TGF-Alha, C-HA-RAS, and C-ErbB2 genes. 112
Oral antisense targeting protein kinase A type I causes antitumor and apoptotic effect in human cancer cells in vitro and in vivo and has cooperative activity in combination with antisense bcl-2. 112
Growth inhibition of tumor cells by epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 is associated with upregulation of p27 and p21 cyclin-dependent kinase inhibitors. 110
Adjuvant Treatment for Locally Advanced Rectal Cancer Patients After Preoperative Chemoradiotherapy: When, and for Whom? 110
DNA index of ovarian carcinomas from 56 different patients: in vivo, in vitro studies. 109
TGFb inhibits rat thyroid cell proliferation without alterations in the expression of THS-induced cell cycle-related genes. Vol :pp , 109
Type-I isoform of PKA is involved in the control of cell proliferation and oncogene transformation of human mammary epithelial cells.Therapeutic implications 109
DNA-flow cytometry (ploidy and S-phase fraction) as prognostic factor in a retrospectine series of 515 primary breast cancer. 106
Cell growth-inhibition and cell cycle perturbations induced by a new synthetic iminoquinone, 5H-pyridophenoxazin-5-one, in human breast carcinoma cell lines. 106
The expression of proliferating cell nuclear antigen in paraffin sections of peripheral, node-negative non-small cell lung cancer. 105
Inhibition of NF-kB activity potentiates ionizing radiation and cisplatin induced cell killing of anaplastic thyroid carcinoma cells AACR Meeting Abstracts, Apr 2006; 2006: 1038. 105
Critical role of both p27kip1 and p21cip1/waf1 in the antiproliferative effect of ZD1839 (‘Iressa’), an epidermal growth factor receptor tyrosine kinase inhibitor, in head and neck squamous carcinoma cells. 104
Synergistic anti-proliferative and pro-apoptotic activity of combined therapy with bortezomib, a proteasome inhibitor, with anti-epidermal growth factor receptor (EGFR) drugs in human cancer cells. 103
Predictive factors of response to neoadjuvant chemoradiotherapy in rectal cancer patirnts. 103
A phase I/II trial of gefitinib and radiotherapy in patients with locally advanced inoperable squamous cell carcinoma of the head and neck. 102
POLY(ADENOSINE DIPHOSPHATE-RIBOSE) POLYMERASE 1 EXPRESSION IN MALIGNANT MELANOMAS FROM PHOTOEXPOSED AREAS OF THE HEAD AND NECK REGION. 102
PRECLINICAL AND PHASE I STUDY OF OXALIPLATIN AND TOPOTECAN IN COMBINATION IN HUMAN CANCER. 102
8-Chloro-cAMP enhances the growth inhibitory effect of cytotoxic drugs in human colon cancer cells 100
Enzastaurin inhibits tumors sensitive and resistant to anti-EGFR drugs 100
Blast cells DNA content in childhood leukemias. 99
Growth arrest, apoptosis and potentiation of 5-fluorouracil and Raltitrexed cytotoxic effect induced by histone deacetylase inhibitor SAHA in colorectal cancer cells. 99
IgE receptors. 99
A phase II study of biweekly oxaliplatin plus infusional 5-fluorouracil and folinic acid (FOLFOX-4) as first-line treatment of advanced gastric cancer patients. 98
Suppression of malignancy targeting the intracellular signal transducing proteins of cAMP: the use of site selective cAMP analogs, antisense strategy, and gene-transfer. 98
Neo-adjuvant treatment of rectal cancer with capecitabine and oxaliplatin in combination with radiotherapy: a phase II study. 97
The farnesyltransferase inhibitor R115777 (Zanestra) synergizes with ionizing radiation in inducing cell cycle perturbation and growth inhibition of human epidermoid head and neck cancer cells. 97
Cell ploidy in 19 Wilms tumors by flow-cytometry of cell suspensions prepared from paraffina embedded sections. 97
Synergistic inhibition of growth and induction of apoptosis by 8-chloro-cAMP and paclitaxel or cisplatin in human cancer cells. 95
EGF-R tyrosyne kinase as new target in melanoma treatment; Synergistic effect of IFN alpha in combination with ZD1839 )Iressa) , an EGFR tyrosine kinase inhibitor. 94
Epidermal growth factor (EGFR) and Transferrin (TRFR) receptor upregulation is induced by arabinoside cytosine (ARA-C) on human tumor cells. 93
EPIGENETIC FACTORS IN HEREDITARY BREAST CANCER 93
P53 expression in non-small-cell lung-cancer. Clinical and biological correlations. 93
Antisense-protein kinase A: a single-gene-based therapeutic approach. 92
Synerglstic antltumor effect by novel modified oligonucleotides targeting PKAI combined with cytotoxic drugs or monoclonal antibodies. 92
Multidisciplinary Approach to Patient with Malignant Melanoma 92
Abstract 4017: Anti-tumor activity of a BRAF inhibitor and IFNα combination in BRAF mutant melanoma 92
Altre Neoplasie 91
Bevacizumab maintenance in metastatic colorectal cancer: How long?. 91
Farsi promotori di salute: “Safe Sun Coast” 91
Antisense DNA-targeting protein kinase A-RIA subunit: a novel approach to cancer treatment. 90
p53 alterations in non-small cell lung cancers correlate with metastatic involvement of hilar and mediastinal lymph nodes. 90
TESI DI DOTTORATO: Hereditary and familial breast and ovarian cancer: spectrum of related tumors. CANDIDATO: M.Pensabene. RELATORE: S.Pepe 90
Phase I-II study of sequential combination of XELOX and bevacizumab plus erlotinib (XELOX-TARAV) in first line colorectal patients:Run in phase I part 90
Antitumor activity of sequential treatment with topotecan and anti-epidermal growth factor receptor monoclonal antibody C225. 89
Predictive factors of complete response to neoadjuvant chemoradiotherapy in patients with rectal cancer. 89
Measurement of neovascularization is an independent prognosticator of survival in node-negative breast cancer patients with long-lerm follow-up. 89
EGF activates an inducible survival response via the RAS -> Erk-1/2 pathway to counteract interferon-alfa-mediated apoptosis in epidermoid cancer cells. 89
Key role of the cyclin-dependent kinase inhibitor p27kip1 for embryonal carcinoma cell survival and differentiation. 89
REPLY TO BRCA2 SPLICE SITE MUTATIONS IN ITALIAN BREAST/OVARIAN CANCER FAMILY. 89
Retroviral vector-mediated overexpression of the RIIbeta subunit of the cAMP-dependent protein kinase induces differentiation in human leukemia cells and reverts the transformed phenotype of mouse fibroblasts. 88
Twenty-year results of the Naples GUN randomized trial: predictive factors of adjuvant tamoxifen efficacy in early breast cancer. 88
Markers of cell-proliferation (p21, PCNA, S-Phase) as prognostic factors in papillary thyroid carcinoma. 88
Cooperative effect of 8-Cl-cAMP and rhGM-CSF on the differentiation of HL-60 human leukemia-cells. 88
Interferon-alpha induces apoptosis in human KB cells through a stress-dependent mitogen activated protein kinase pathway death is antagonized by epidermal growth factor. 87
Introducing an autophosphorylation site mutation in the RII-beta regulatory subunit of cAMP-dependent Protein-Kinase abolishes the RII-beta -mediated regulatory function. 87
Overexpression of the RIα subunit of Protein Kinase A confers hypersensitivity to topoisomerase II inhibitors and 8-Chloro-cyclic Adenosine 3′,5′-Monophosphate in chinese hamster ovary cells. 87
Synergistic antitumor activity of epidermal growth factor receptor tyrosine kinase inhibitor gefitinib and IFN-A in head and neck cancer cells in vitro and in vivo 86
Phorbol-12-myristate-13-acetate (PMA) induces resistance of human melanoma cells to NK and LAK-mediated cytotoxicity. 86
Flow-cytometric detection of the RI-alpha subunit of Type-I cAMP-dependent protein-kinase in human-cells 86
Unhydrolyzable analogs of Adenosine 3'/5'-monophosphate demonstrating growth-inhibition and differentiation in human cancer-cells. 86
Antitumor Agents. 5. Synthesis, structure−activity relationships, and biological evaluation of dimethyl-5H-pyridophenoxazin-5-ones, tetrahydro-5H-benzopyridophenoxazin-5-ones, and 5H-benzopyridophenoxazin-5-ones with potent antiproliferative activity. 86
Counteracting resistance to treatments in solid tumors. 86
Diagnostic utility of BRAFV600E mutation testing in thyroid nodules in elderly patients 85
Totale 11.630
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Categoria #
all - tutte 53.562
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 53.562
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/20211.342 0 151 155 14 164 30 171 11 153 2 168 323
2021/20221.181 4 0 3 35 30 39 15 54 189 161 141 510
2022/20231.923 190 91 53 246 271 420 2 169 357 10 74 40
2023/20241.135 80 136 66 27 67 142 276 61 28 39 47 166
2024/20252.370 78 33 52 94 147 364 392 242 317 102 243 306
2025/20261.265 572 693 0 0 0 0 0 0 0 0 0 0
Totale 17.493