RODRIQUEZ, Manuela
 Distribuzione geografica
Continente #
NA - Nord America 3.181
EU - Europa 896
AS - Asia 400
Continente sconosciuto - Info sul continente non disponibili 4
AF - Africa 2
SA - Sud America 1
Totale 4.484
Nazione #
US - Stati Uniti d'America 3.170
IT - Italia 365
CN - Cina 226
UA - Ucraina 212
VN - Vietnam 95
SE - Svezia 91
IE - Irlanda 77
DE - Germania 66
TR - Turchia 58
FI - Finlandia 44
GB - Regno Unito 14
CA - Canada 8
IN - India 7
RU - Federazione Russa 7
NL - Olanda 6
FR - Francia 5
SG - Singapore 5
EU - Europa 4
IL - Israele 4
MX - Messico 3
CH - Svizzera 2
CZ - Repubblica Ceca 2
KR - Corea 2
NO - Norvegia 2
PH - Filippine 2
AT - Austria 1
BR - Brasile 1
CM - Camerun 1
EG - Egitto 1
JP - Giappone 1
PL - Polonia 1
RO - Romania 1
Totale 4.484
Città #
Ann Arbor 870
Woodbridge 386
Chandler 366
Houston 267
Jacksonville 267
Princeton 204
Wilmington 191
Dong Ket 95
Salerno 81
Dublin 77
Ashburn 59
Izmir 57
Nanjing 51
Andover 49
Beijing 48
Boardman 41
Pellezzano 40
Dearborn 38
Hebei 24
Mestre 21
Fairfield 16
Changsha 15
Shenyang 15
Nanchang 14
Jiaxing 12
Norwalk 12
Düsseldorf 11
Jinan 11
Redwood City 11
Tianjin 10
Falls Church 7
Indiana 7
Ottawa 7
Washington 7
Los Angeles 6
Seattle 6
Zhengzhou 6
Naples 5
Pune 5
Rome 5
Singapore 5
Torino 5
Venezia 5
Fisciano 4
New York 4
Warrington 4
Afragola 3
Cambridge 3
Guangzhou 3
Mercato San Severino 3
Mexico 3
Milan 3
Nettuno 3
Nocera Inferiore 3
San Francisco 3
Shanghai 3
Siena 3
Spinea 3
Taizhou 3
Tappahannock 3
Agropoli 2
Amsterdam 2
Angri 2
Bologna 2
Caianello 2
Florence 2
Fremont 2
Groningen 2
Leawood 2
London 2
Lucca 2
Mumbai 2
Napoli 2
Ningbo 2
Pavia 2
Ponte San Nicolò 2
Rende 2
San Diego 2
Stockholm 2
Striano 2
Trieste 2
Tromsø 2
Aversa 1
Bern 1
Brno 1
Cairo 1
Capua 1
Cava 1
Charlotte 1
Genova 1
Giugliano In Campania 1
Giussano 1
Grumo Nevano 1
Haikou 1
Hamburg 1
Hangzhou 1
Hefei 1
Helsinki 1
Iesi 1
Kunming 1
Totale 3.551
Nome #
1,3-Cycloaddition of nitrile oxides in ionic liquids. An easier route to 3-carboxy isoxazolines, potential constrained glutamic acid analogues. 223
TRYPTOPHAN-BASED LINEAR DIPEPTIDES AND 1,4-DIKETOPIPERAZINES AS SIMPLIFIED SCAFFOLDS OF THE NATURAL CYCLOTETRAPEPTIDE FR235222 126
Investigating the Neuroprotective Effects of Turmeric Extract: Structural Interactions of β-Amyloid Peptide with Single Curcuminoids 124
Gentamicina: derivatizzazione molecolare per migliorare la maneggevolezza sintetica e la farmacocinetica 119
TARGETING STAT3 IN CANCER INHIBITION 114
Benzodiazepine Scaffold as Drug-like Molecular Simplification of FR235222: A Chemical Tool for Exploring HDAC Inhibition 113
Build/couple/pair strategy: From nonchiral molecules to unbiased scaffolds, a methodological approach for the optimization of microwave-assisted intra-molecular Diels-Alder reaction of furans 106
Fast determination of underivatized gentamicin C components and impurities by LC-MS using a porous graphitic carbon stationary phase 103
SYNTHESIS AND BIOLOGICAL EVALUATION OF SMALL MOLECULES DERIVATIVES OF THE NATURAL HISTONE DEACETYLASE INHIBITOR FR235222 99
Is it time to integrate sex and gender into drug design and development? 99
Design and Synthesis of cyclopeptide analogues of the potent Histone deacetylase inhibitor FR235222 98
Sintesi di derivati SAHA-like utilizzati per indagare sulla selettività verso le diverse isoforme HDAC 98
Synthesis of Heterocycles via Microwave-Assisted Cycloadditions and Cyclocondensations 96
Histone deacetylase inhibitors in the treatment of cancer: overview and perspectives 96
The isoprenoid derivative N6-benzyladenosine (CM223) exerts antitumor effect in glioma patient-derived primary cells through the mevalonate pathway 96
STEROIDAL HYDROXAMIC ACID DERIVATIVES: A STRUCTURALLY NOVEL CLASS OF HDAC INHIBITORS 94
Molecular modeling studies toward the structural optimization of new cyclopeptide-based HDAC inhibitors modeled on the natural product FR235222 93
Solid-Phase Synthesis of Conformationally Constrained Peptidomimetics Based on a 3,6-Disubstituted-1,4-diazepan-2,5-dione Core 92
Facile Baeyer–Villiger oxidation of cyclic ketones: conventional versus microwave-assisted approach 92
Total Synthesis, NMR Solution Structure, and Binding Model of the Potent Histone Deacetylase Inhibitor FR235222 90
Chemistry and biology of anti-inflammatory marine natural products: molecules interfering with cyclooxygenase, NF-κB and other unidentified targets 90
Epoxidation of 17-oxo-15,16-methylene steroids with sulfoxonium ylides 90
Histone deacetylase inhibitor FR235222 sensitizes human prostate adenocarcinoma cells to apoptosis through up-regulation of annexin A1. 89
Transformation of Glutamic Acid into (S)-Benzyl 2-(dibenzylamino)-6-(dimethoxyphosphoryl)-5-oxohexanoate for a Convenient Access to 5-Substituted Prolines 87
A serum nuclear magnetic resonance-based metabolomic signature of antiphospholipid syndrome 87
N-thioalkylcarbazoles derivatives as new anti-proliferative agents: synthesis, characterisation and molecular mechanism evaluation 85
Oxime amides as a novel zinc binding group in histone deacetylase inhibitors: synthesis, biological activity, and computational evaluation 84
A simple procedure for the transformation of L-glutamic acid into the corresponding γ-aldehyde 84
STRUCTURAL FEATURES OF PEPTIDES DERIVED FROM FELINE IMMUNODEFICIENCY VIRUS TM-GLYCOPROTEIN 84
Synthesis of 2-Amino-8-oxodecanoic Acids (Aodas) Present in Natural Histone Deacetylase Inhibitors. 80
Synthesis and application in SPPS of a stable amino acid isoster of palmitoyl cysteine 78
β-Amyloid-acetylcholine molecular interaction: New role of cholinergic mediators in anti-Alzheimer therapy? 78
Microwaves enhance cyclisation of tetrapeptides 77
Synthesis, structural aspects and cytotoxicity of the natural cyclopeptides yunnanins A, C and phakellistatins 1, 10 76
Colorimetric tools for solid-phase organic synthesis 75
Total Synthesis and Structural Elucidation of Azaspiracid-1. Construction of Key Building Blocks for Originally Proposed Structure. 74
Ionic Liquid as a Suitable Phase for Multistep Parallel Synthesis of an Array of Isoxazolines 74
Synthesis of Enantiopure 7-Substituted Azepane-2-Carboxylic Acids as Templates for Conformationally Constrained Peptidomimetics 73
Sensible Improvements Induced by Ionic Liquids in the Reaction of Modified Carbasugars with Bases for the Building of Constrained Carbanucleosides 72
Identification of CM223 as a new ligand of farnesyl pyrophosphate synthase with improved antiglioma action 69
Skeletally Diverse Small Molecules Using a Build/Couple/Pair Strategy 68
Downregulation of Hypoxia-related Responses by Novel Antitumor Histone Deacetylase Inhibitors in MDAMB231 Breast Cancer Cells 68
Specific Targeting Highly Conserved Residues in the HIV-1 Reverse Transcriptase Primer Grip Region. Design, Synthesis, and Biological Evaluation of Novel, Potent, and Broad Spectrum NNRTIs with Antiviral Activity 64
Developing molecular diversity in the construction of a family of bicyclic isoxazolines scaffolds: Control of regio-and diastereoselectivities 64
Synthesis of kainoids via a highly stereoselective hydroformylation of kainic acid. 59
Total Synthesis and Biological Evaluation of Halipeptins A and D and Analogues. 56
Effects of FR235222, a novel HDAC inhibitor, in proliferation and apoptosis of human leukaemia cell lines: role of annexin A1 56
Chemistry and Biology of Chromatin Remodeling Agents: State of Art and Future Perspectives of HDAC Inhibitors 55
Synthesis and biological evaluation of Santacruzamate-A based analogues 54
Histone Deacetylase Inhibitors in the Treatment of Hematological Malignancies 52
LGP1, a histone deacetylase inhibitor analogue of FR235222, sensitizes promyelocytic leukemia U937 cells to TRAIL-mediated apoptosis 51
Ganoderma lucidum ethanol extracts enhance re-epithelialization and prevent keratinocytes from free-radical injury 42
Saliva of patients affected by salivary gland tumour: An NMR metabolomics analysis 39
NMR for screening and a biochemical assay: Identification of new FPPS inhibitors exerting anticancer activity 39
Fabrication of Novel Bio-Composites Based on Rice Milk for the Delivery of Capsaicinoids as Green Herbicides against Cynodon dactylon Weed 24
A New Approach to Supramolecular Structure Determination in Pharmaceutical Preparation of Self-Assembling Peptides: A Case Study of Lanreotide Autogel 23
Discovery and Optimization of Indoline-Based Compounds as Dual 5-LOX/sEH Inhibitors: In Vitro and In Vivo Anti-Inflammatory Characterization 20
Structural analysis of a simplified model reproducing SARS-CoV-2 S RBD/ACE2 binding site 17
Towards an improvement of anticancer activity of benzyl adenosine analogs 15
Cocoa Extract Provides Protection against 6-OHDA Toxicity in SH-SY5Y Dopaminergic Neurons by Targeting PERK 11
Salicylic Acid Release from Syndiotactic Polystyrene Staple Fibers 2
Totale 4.656
Categoria #
all - tutte 11.440
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 11.440


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/201974 0 0 0 0 0 0 0 0 0 0 69 5
2019/2020532 130 31 60 5 41 10 44 8 47 73 77 6
2020/2021498 7 44 46 9 72 23 54 5 50 7 60 121
2021/2022410 1 1 1 12 34 17 8 20 57 42 62 155
2022/2023738 59 74 12 138 95 152 1 65 101 2 28 11
2023/2024203 28 46 13 9 16 41 16 9 8 17 0 0
Totale 4.656