RODRIQUEZ, Manuela
 Distribuzione geografica
Continente #
NA - Nord America 3.280
EU - Europa 1.240
AS - Asia 807
SA - Sud America 143
AF - Africa 7
Continente sconosciuto - Info sul continente non disponibili 4
Totale 5.481
Nazione #
US - Stati Uniti d'America 3.262
IT - Italia 409
CN - Cina 267
SG - Singapore 259
UA - Ucraina 213
RU - Federazione Russa 179
BR - Brasile 134
DE - Germania 106
VN - Vietnam 101
SE - Svezia 92
IE - Irlanda 77
TR - Turchia 60
FI - Finlandia 55
HK - Hong Kong 53
EE - Estonia 38
KR - Corea 36
GB - Regno Unito 25
IN - India 12
CA - Canada 10
NL - Olanda 10
BG - Bulgaria 8
MX - Messico 8
AR - Argentina 5
CZ - Repubblica Ceca 5
FR - Francia 5
PL - Polonia 5
BD - Bangladesh 4
EU - Europa 4
IL - Israele 4
IQ - Iraq 3
AT - Austria 2
CH - Svizzera 2
ES - Italia 2
MK - Macedonia 2
NO - Norvegia 2
PH - Filippine 2
RO - Romania 2
ZA - Sudafrica 2
AE - Emirati Arabi Uniti 1
AF - Afghanistan, Repubblica islamica di 1
CM - Camerun 1
CO - Colombia 1
DZ - Algeria 1
EC - Ecuador 1
EG - Egitto 1
JO - Giordania 1
JP - Giappone 1
LT - Lituania 1
MA - Marocco 1
PE - Perù 1
SA - Arabia Saudita 1
SN - Senegal 1
UZ - Uzbekistan 1
VE - Venezuela 1
Totale 5.481
Città #
Ann Arbor 870
Woodbridge 386
Chandler 366
Houston 267
Jacksonville 267
Princeton 204
Wilmington 191
Singapore 109
Dong Ket 95
Salerno 82
Dublin 77
Ashburn 67
Izmir 57
Beijing 55
Hong Kong 51
Nanjing 51
Andover 49
Boardman 42
Pellezzano 40
Dearborn 38
Moscow 38
Tallinn 38
Munich 35
Hebei 24
Mestre 21
Naples 18
Fairfield 16
Changsha 15
Shenyang 15
Nanchang 14
Fisciano 13
Jiaxing 13
Norwalk 12
Düsseldorf 11
Jinan 11
Los Angeles 11
Redwood City 11
Tianjin 11
Turku 9
The Dalles 8
Falls Church 7
Indiana 7
Ottawa 7
San Francisco 7
Seattle 7
Washington 7
Belo Horizonte 6
Dallas 6
London 6
Shanghai 6
Zhengzhou 6
Guangzhou 5
New York 5
Nuremberg 5
Pune 5
Rome 5
Sarno 5
São Paulo 5
Torino 5
Venezia 5
Amsterdam 4
Brooklyn 4
Columbus 4
Rio de Janeiro 4
Santa Clara 4
São Bernardo do Campo 4
Warrington 4
Warsaw 4
Afragola 3
Brasília 3
Brno 3
Cambridge 3
Cormano 3
Helsinki 3
Mercato San Severino 3
Mexico 3
Mexico City 3
Milan 3
Mumbai 3
Nettuno 3
Nocera Inferiore 3
Salvador 3
Siena 3
Spinea 3
Stockholm 3
Taizhou 3
Tappahannock 3
Agropoli 2
Alvorada 2
Angri 2
Betim 2
Bologna 2
Brumadinho 2
Caianello 2
Curitiba 2
Diadema 2
Domicella 2
Extrema 2
Florence 2
Fremont 2
Totale 3.940
Nome #
1,3-Cycloaddition of nitrile oxides in ionic liquids. An easier route to 3-carboxy isoxazolines, potential constrained glutamic acid analogues. 278
Benzodiazepine Scaffold as Drug-like Molecular Simplification of FR235222: A Chemical Tool for Exploring HDAC Inhibition 148
Investigating the Neuroprotective Effects of Turmeric Extract: Structural Interactions of β-Amyloid Peptide with Single Curcuminoids 145
TRYPTOPHAN-BASED LINEAR DIPEPTIDES AND 1,4-DIKETOPIPERAZINES AS SIMPLIFIED SCAFFOLDS OF THE NATURAL CYCLOTETRAPEPTIDE FR235222 136
Gentamicina: derivatizzazione molecolare per migliorare la maneggevolezza sintetica e la farmacocinetica 132
TARGETING STAT3 IN CANCER INHIBITION 129
Fast determination of underivatized gentamicin C components and impurities by LC-MS using a porous graphitic carbon stationary phase 121
Build/couple/pair strategy: From nonchiral molecules to unbiased scaffolds, a methodological approach for the optimization of microwave-assisted intra-molecular Diels-Alder reaction of furans 119
Design and Synthesis of cyclopeptide analogues of the potent Histone deacetylase inhibitor FR235222 117
The isoprenoid derivative N6-benzyladenosine (CM223) exerts antitumor effect in glioma patient-derived primary cells through the mevalonate pathway 117
Sintesi di derivati SAHA-like utilizzati per indagare sulla selettività verso le diverse isoforme HDAC 112
Is it time to integrate sex and gender into drug design and development? 111
SYNTHESIS AND BIOLOGICAL EVALUATION OF SMALL MOLECULES DERIVATIVES OF THE NATURAL HISTONE DEACETYLASE INHIBITOR FR235222 110
Facile Baeyer–Villiger oxidation of cyclic ketones: conventional versus microwave-assisted approach 108
Chemistry and biology of anti-inflammatory marine natural products: molecules interfering with cyclooxygenase, NF-κB and other unidentified targets 107
Synthesis of Heterocycles via Microwave-Assisted Cycloadditions and Cyclocondensations 107
Epoxidation of 17-oxo-15,16-methylene steroids with sulfoxonium ylides 106
STEROIDAL HYDROXAMIC ACID DERIVATIVES: A STRUCTURALLY NOVEL CLASS OF HDAC INHIBITORS 105
A serum nuclear magnetic resonance-based metabolomic signature of antiphospholipid syndrome 105
Solid-Phase Synthesis of Conformationally Constrained Peptidomimetics Based on a 3,6-Disubstituted-1,4-diazepan-2,5-dione Core 104
Histone deacetylase inhibitors in the treatment of cancer: overview and perspectives 104
Identification of CM223 as a new ligand of farnesyl pyrophosphate synthase with improved antiglioma action 104
STRUCTURAL FEATURES OF PEPTIDES DERIVED FROM FELINE IMMUNODEFICIENCY VIRUS TM-GLYCOPROTEIN 103
Total Synthesis, NMR Solution Structure, and Binding Model of the Potent Histone Deacetylase Inhibitor FR235222 101
Molecular modeling studies toward the structural optimization of new cyclopeptide-based HDAC inhibitors modeled on the natural product FR235222 101
Histone deacetylase inhibitor FR235222 sensitizes human prostate adenocarcinoma cells to apoptosis through up-regulation of annexin A1. 100
Oxime amides as a novel zinc binding group in histone deacetylase inhibitors: synthesis, biological activity, and computational evaluation 98
N-thioalkylcarbazoles derivatives as new anti-proliferative agents: synthesis, characterisation and molecular mechanism evaluation 98
A simple procedure for the transformation of L-glutamic acid into the corresponding γ-aldehyde 95
Transformation of Glutamic Acid into (S)-Benzyl 2-(dibenzylamino)-6-(dimethoxyphosphoryl)-5-oxohexanoate for a Convenient Access to 5-Substituted Prolines 93
Colorimetric tools for solid-phase organic synthesis 92
β-Amyloid-acetylcholine molecular interaction: New role of cholinergic mediators in anti-Alzheimer therapy? 92
Synthesis of 2-Amino-8-oxodecanoic Acids (Aodas) Present in Natural Histone Deacetylase Inhibitors. 88
Synthesis and application in SPPS of a stable amino acid isoster of palmitoyl cysteine 86
Downregulation of Hypoxia-related Responses by Novel Antitumor Histone Deacetylase Inhibitors in MDAMB231 Breast Cancer Cells 85
Microwaves enhance cyclisation of tetrapeptides 83
Total Synthesis and Structural Elucidation of Azaspiracid-1. Construction of Key Building Blocks for Originally Proposed Structure. 82
Synthesis, structural aspects and cytotoxicity of the natural cyclopeptides yunnanins A, C and phakellistatins 1, 10 82
Ionic Liquid as a Suitable Phase for Multistep Parallel Synthesis of an Array of Isoxazolines 81
Sensible Improvements Induced by Ionic Liquids in the Reaction of Modified Carbasugars with Bases for the Building of Constrained Carbanucleosides 80
Synthesis of Enantiopure 7-Substituted Azepane-2-Carboxylic Acids as Templates for Conformationally Constrained Peptidomimetics 80
Skeletally Diverse Small Molecules Using a Build/Couple/Pair Strategy 77
Developing molecular diversity in the construction of a family of bicyclic isoxazolines scaffolds: Control of regio-and diastereoselectivities 77
Chemistry and Biology of Chromatin Remodeling Agents: State of Art and Future Perspectives of HDAC Inhibitors 74
Specific Targeting Highly Conserved Residues in the HIV-1 Reverse Transcriptase Primer Grip Region. Design, Synthesis, and Biological Evaluation of Novel, Potent, and Broad Spectrum NNRTIs with Antiviral Activity 71
Effects of FR235222, a novel HDAC inhibitor, in proliferation and apoptosis of human leukaemia cell lines: role of annexin A1 70
Synthesis and biological evaluation of Santacruzamate-A based analogues 69
Ganoderma lucidum ethanol extracts enhance re-epithelialization and prevent keratinocytes from free-radical injury 68
Synthesis of kainoids via a highly stereoselective hydroformylation of kainic acid. 67
LGP1, a histone deacetylase inhibitor analogue of FR235222, sensitizes promyelocytic leukemia U937 cells to TRAIL-mediated apoptosis 65
Histone Deacetylase Inhibitors in the Treatment of Hematological Malignancies 63
NMR for screening and a biochemical assay: Identification of new FPPS inhibitors exerting anticancer activity 63
Total Synthesis and Biological Evaluation of Halipeptins A and D and Analogues. 59
Saliva of patients affected by salivary gland tumour: An NMR metabolomics analysis 56
A New Approach to Supramolecular Structure Determination in Pharmaceutical Preparation of Self-Assembling Peptides: A Case Study of Lanreotide Autogel 51
Cocoa Extract Provides Protection against 6-OHDA Toxicity in SH-SY5Y Dopaminergic Neurons by Targeting PERK 47
Fabrication of Novel Bio-Composites Based on Rice Milk for the Delivery of Capsaicinoids as Green Herbicides against Cynodon dactylon Weed 44
Discovery and Optimization of Indoline-Based Compounds as Dual 5-LOX/sEH Inhibitors: In Vitro and In Vivo Anti-Inflammatory Characterization 43
Towards an improvement of anticancer activity of benzyl adenosine analogs 33
Structural analysis of a simplified model reproducing SARS-CoV-2 S RBD/ACE2 binding site 30
Structural analysis of a simplified model reproducing SARS-CoV-2 S RBD/ACE2 binding site 28
Salicylic Acid Release from Syndiotactic Polystyrene Staple Fibers 27
Bioelectrospun fibers loaded with Ganoderma lucidum green extracts as a novel bio/medical patch for wound healing applications 22
NANOPOROUS POLYMERS FOR MEDICAL AND COSMECEUTICAL APPLICATIONS 13
Totale 5.662
Categoria #
all - tutte 18.710
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 18.710


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021498 7 44 46 9 72 23 54 5 50 7 60 121
2021/2022410 1 1 1 12 34 17 8 20 57 42 62 155
2022/2023738 59 74 12 138 95 152 1 65 101 2 28 11
2023/2024261 28 46 13 9 16 41 16 9 8 17 14 44
2024/2025899 36 8 14 91 25 91 153 48 131 53 126 123
2025/202649 49 0 0 0 0 0 0 0 0 0 0 0
Totale 5.662