RODRIQUEZ, Manuela
 Distribuzione geografica
Continente #
AS - Asia 6.741
NA - Nord America 4.963
EU - Europa 1.756
SA - Sud America 282
Continente sconosciuto - Info sul continente non disponibili 187
AF - Africa 45
OC - Oceania 3
Totale 13.977
Nazione #
HK - Hong Kong 5.056
US - Stati Uniti d'America 4.859
SG - Singapore 724
IT - Italia 709
CN - Cina 408
VN - Vietnam 236
BR - Brasile 225
UA - Ucraina 218
RU - Federazione Russa 187
DE - Germania 133
SE - Svezia 97
IE - Irlanda 77
TR - Turchia 74
FR - Francia 69
FI - Finlandia 61
GB - Regno Unito 60
IN - India 56
CA - Canada 50
KR - Corea 46
EE - Estonia 38
MX - Messico 35
AR - Argentina 27
PL - Polonia 25
JP - Giappone 23
BD - Bangladesh 22
NL - Olanda 17
ES - Italia 16
IQ - Iraq 13
ID - Indonesia 11
PH - Filippine 11
ZA - Sudafrica 11
CO - Colombia 9
PK - Pakistan 9
BG - Bulgaria 8
CH - Svizzera 8
MA - Marocco 8
EC - Ecuador 6
IL - Israele 6
MY - Malesia 6
VE - Venezuela 6
CL - Cile 5
CZ - Repubblica Ceca 5
KE - Kenya 5
TH - Thailandia 5
UZ - Uzbekistan 5
AT - Austria 4
DO - Repubblica Dominicana 4
EG - Egitto 4
EU - Europa 4
JO - Giordania 4
LT - Lituania 4
AE - Emirati Arabi Uniti 3
DZ - Algeria 3
ET - Etiopia 3
JM - Giamaica 3
LB - Libano 3
MK - Macedonia 3
PA - Panama 3
SA - Arabia Saudita 3
TN - Tunisia 3
AL - Albania 2
CI - Costa d'Avorio 2
CM - Camerun 2
GR - Grecia 2
GT - Guatemala 2
NO - Norvegia 2
NP - Nepal 2
OM - Oman 2
PE - Perù 2
PS - Palestinian Territory 2
RO - Romania 2
RS - Serbia 2
SK - Slovacchia (Repubblica Slovacca) 2
SY - Repubblica araba siriana 2
AF - Afghanistan, Repubblica islamica di 1
AU - Australia 1
AZ - Azerbaigian 1
BF - Burkina Faso 1
BN - Brunei Darussalam 1
BT - Bhutan 1
BY - Bielorussia 1
CR - Costa Rica 1
CU - Cuba 1
DK - Danimarca 1
GE - Georgia 1
GP - Guadalupe 1
HN - Honduras 1
KH - Cambogia 1
KW - Kuwait 1
KZ - Kazakistan 1
LA - Repubblica Popolare Democratica del Laos 1
LV - Lettonia 1
MG - Madagascar 1
MT - Malta 1
NA - Namibia 1
NI - Nicaragua 1
PF - Polinesia Francese 1
PR - Porto Rico 1
PT - Portogallo 1
PW - Palau 1
Totale 13.790
Città #
Hong Kong 5.045
Ann Arbor 870
San Jose 432
Singapore 395
Woodbridge 386
Chandler 366
Houston 273
Jacksonville 268
Ashburn 255
Princeton 204
Wilmington 193
Dallas 185
Milan 175
Council Bluffs 124
Beijing 100
Dong Ket 95
Salerno 85
Dublin 77
The Dalles 72
Izmir 57
Lauterbourg 56
Los Angeles 51
Munich 51
Nanjing 51
Andover 49
New York 48
Boardman 42
Ho Chi Minh City 40
Pellezzano 40
Moscow 39
Dearborn 38
Rome 38
Tallinn 38
Hanoi 33
Santa Clara 33
Naples 31
São Paulo 29
Hebei 24
Tokyo 23
Warsaw 23
Mestre 21
Denver 18
Phoenix 18
Brooklyn 16
Fairfield 16
Changsha 15
Chennai 15
Chicago 15
Figino 15
Shenyang 15
Nanchang 14
Toronto 14
Fisciano 13
Jiaxing 13
London 13
Mexico City 13
Atlanta 12
Montreal 12
Norwalk 12
Düsseldorf 11
Jinan 11
Johannesburg 11
Redwood City 11
San Francisco 11
Seattle 11
Tianjin 11
Turku 11
Frankfurt am Main 10
Amsterdam 9
Memphis 9
Orem 9
Poplar 9
Washington 9
Baghdad 8
Da Nang 8
Seoul 8
Shanghai 8
Stockholm 8
Turin 8
Falls Church 7
Helsinki 7
Indiana 7
Ottawa 7
Rio de Janeiro 7
Belo Horizonte 6
Boston 6
Brasília 6
Haiphong 6
Nuremberg 6
Philadelphia 6
Zhengzhou 6
Ankara 5
Biên Hòa 5
Columbus 5
Guangzhou 5
Jakarta 5
Manchester 5
Mumbai 5
New Delhi 5
Pune 5
Totale 11.027
Nome #
Histone deacetylase inhibitor FR235222 sensitizes human prostate adenocarcinoma cells to apoptosis through up-regulation of annexin A1. 1.286
Benzodiazepine Scaffold as Drug-like Molecular Simplification of FR235222: A Chemical Tool for Exploring HDAC Inhibition 662
N-thioalkylcarbazoles derivatives as new anti-proliferative agents: synthesis, characterisation and molecular mechanism evaluation 631
SYNTHESIS AND BIOLOGICAL EVALUATION OF SMALL MOLECULES DERIVATIVES OF THE NATURAL HISTONE DEACETYLASE INHIBITOR FR235222 593
Salicylic Acid Release from Syndiotactic Polystyrene Staple Fibers 567
Chemistry and biology of anti-inflammatory marine natural products: molecules interfering with cyclooxygenase, NF-κB and other unidentified targets 564
Bioelectrospun fibers loaded with Ganoderma lucidum green extracts as a novel bio/medical patch for wound healing applications 511
Downregulation of Hypoxia-related Responses by Novel Antitumor Histone Deacetylase Inhibitors in MDAMB231 Breast Cancer Cells 432
1,3-Cycloaddition of nitrile oxides in ionic liquids. An easier route to 3-carboxy isoxazolines, potential constrained glutamic acid analogues. 344
The isoprenoid derivative N6-benzyladenosine (CM223) exerts antitumor effect in glioma patient-derived primary cells through the mevalonate pathway 338
Sintesi di derivati SAHA-like utilizzati per indagare sulla selettività verso le diverse isoforme HDAC 273
NANOPOROUS POLYMERS FOR MEDICAL AND COSMECEUTICAL APPLICATIONS 272
Fast determination of underivatized gentamicin C components and impurities by LC-MS using a porous graphitic carbon stationary phase 266
Identification of CM223 as a new ligand of farnesyl pyrophosphate synthase with improved antiglioma action 237
Gentamicina: derivatizzazione molecolare per migliorare la maneggevolezza sintetica e la farmacocinetica 222
TARGETING STAT3 IN CANCER INHIBITION 211
Facile Baeyer–Villiger oxidation of cyclic ketones: conventional versus microwave-assisted approach 209
A serum nuclear magnetic resonance-based metabolomic signature of antiphospholipid syndrome 206
Investigating the Neuroprotective Effects of Turmeric Extract: Structural Interactions of β-Amyloid Peptide with Single Curcuminoids 201
TRYPTOPHAN-BASED LINEAR DIPEPTIDES AND 1,4-DIKETOPIPERAZINES AS SIMPLIFIED SCAFFOLDS OF THE NATURAL CYCLOTETRAPEPTIDE FR235222 198
Build/couple/pair strategy: From nonchiral molecules to unbiased scaffolds, a methodological approach for the optimization of microwave-assisted intra-molecular Diels-Alder reaction of furans 183
Design and Synthesis of cyclopeptide analogues of the potent Histone deacetylase inhibitor FR235222 176
STRUCTURAL FEATURES OF PEPTIDES DERIVED FROM FELINE IMMUNODEFICIENCY VIRUS TM-GLYCOPROTEIN 164
Effects of FR235222, a novel HDAC inhibitor, in proliferation and apoptosis of human leukaemia cell lines: role of annexin A1 161
A New Approach to Supramolecular Structure Determination in Pharmaceutical Preparation of Self-Assembling Peptides: A Case Study of Lanreotide Autogel 160
Epoxidation of 17-oxo-15,16-methylene steroids with sulfoxonium ylides 151
Synthesis of Heterocycles via Microwave-Assisted Cycloadditions and Cyclocondensations 150
Structural analysis of a simplified model reproducing SARS-CoV-2 S RBD/ACE2 binding site 149
NMR for screening and a biochemical assay: Identification of new FPPS inhibitors exerting anticancer activity 149
Is it time to integrate sex and gender into drug design and development? 147
Histone deacetylase inhibitors in the treatment of cancer: overview and perspectives 146
Colorimetric tools for solid-phase organic synthesis 145
STEROIDAL HYDROXAMIC ACID DERIVATIVES: A STRUCTURALLY NOVEL CLASS OF HDAC INHIBITORS 144
Total Synthesis, NMR Solution Structure, and Binding Model of the Potent Histone Deacetylase Inhibitor FR235222 144
A simple procedure for the transformation of L-glutamic acid into the corresponding γ-aldehyde 142
Synthesis and biological evaluation of Santacruzamate-A based analogues 142
Solid-Phase Synthesis of Conformationally Constrained Peptidomimetics Based on a 3,6-Disubstituted-1,4-diazepan-2,5-dione Core 140
β-Amyloid-acetylcholine molecular interaction: New role of cholinergic mediators in anti-Alzheimer therapy? 140
Transformation of Glutamic Acid into (S)-Benzyl 2-(dibenzylamino)-6-(dimethoxyphosphoryl)-5-oxohexanoate for a Convenient Access to 5-Substituted Prolines 135
Oxime amides as a novel zinc binding group in histone deacetylase inhibitors: synthesis, biological activity, and computational evaluation 135
Molecular modeling studies toward the structural optimization of new cyclopeptide-based HDAC inhibitors modeled on the natural product FR235222 133
Sensible Improvements Induced by Ionic Liquids in the Reaction of Modified Carbasugars with Bases for the Building of Constrained Carbanucleosides 129
Synthesis of 2-Amino-8-oxodecanoic Acids (Aodas) Present in Natural Histone Deacetylase Inhibitors. 128
Synthesis, structural aspects and cytotoxicity of the natural cyclopeptides yunnanins A, C and phakellistatins 1, 10 128
Ganoderma lucidum ethanol extracts enhance re-epithelialization and prevent keratinocytes from free-radical injury 128
Discovery and Optimization of Indoline-Based Compounds as Dual 5-LOX/sEH Inhibitors: In Vitro and In Vivo Anti-Inflammatory Characterization 124
Fabrication of Novel Bio-Composites Based on Rice Milk for the Delivery of Capsaicinoids as Green Herbicides against Cynodon dactylon Weed 122
Cocoa Extract Provides Protection against 6-OHDA Toxicity in SH-SY5Y Dopaminergic Neurons by Targeting PERK 122
Synthesis and application in SPPS of a stable amino acid isoster of palmitoyl cysteine 121
Chemistry and Biology of Chromatin Remodeling Agents: State of Art and Future Perspectives of HDAC Inhibitors 121
Total Synthesis and Structural Elucidation of Azaspiracid-1. Construction of Key Building Blocks for Originally Proposed Structure. 120
Saliva of patients affected by salivary gland tumour: An NMR metabolomics analysis 120
Developing molecular diversity in the construction of a family of bicyclic isoxazolines scaffolds: Control of regio-and diastereoselectivities 119
Synthesis of Enantiopure 7-Substituted Azepane-2-Carboxylic Acids as Templates for Conformationally Constrained Peptidomimetics 117
Microwaves enhance cyclisation of tetrapeptides 111
Ionic Liquid as a Suitable Phase for Multistep Parallel Synthesis of an Array of Isoxazolines 111
LGP1, a histone deacetylase inhibitor analogue of FR235222, sensitizes promyelocytic leukemia U937 cells to TRAIL-mediated apoptosis 107
Skeletally Diverse Small Molecules Using a Build/Couple/Pair Strategy 106
Synthesis of kainoids via a highly stereoselective hydroformylation of kainic acid. 106
Histone Deacetylase Inhibitors in the Treatment of Hematological Malignancies 103
Towards an improvement of anticancer activity of benzyl adenosine analogs 100
Specific Targeting Highly Conserved Residues in the HIV-1 Reverse Transcriptase Primer Grip Region. Design, Synthesis, and Biological Evaluation of Novel, Potent, and Broad Spectrum NNRTIs with Antiviral Activity 94
Structural analysis of a simplified model reproducing SARS-CoV-2 S RBD/ACE2 binding site 93
Total Synthesis and Biological Evaluation of Halipeptins A and D and Analogues. 88
Totale 13.977
Categoria #
all - tutte 35.074
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 35.074


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022407 0 0 0 12 34 17 8 20 57 42 62 155
2022/2023738 59 74 12 138 95 152 1 65 101 2 28 11
2023/2024261 28 46 13 9 16 41 16 9 8 17 14 44
2024/2025899 36 8 14 91 25 91 153 48 131 53 126 123
2025/20267.755 1.310 2.327 1.850 276 364 172 431 92 247 322 93 271
2026/2027609 92 100 258 159 0 0 0 0 0 0 0 0
Totale 13.977