RODRIQUEZ, Manuela
 Distribuzione geografica
Continente #
NA - Nord America 3.208
EU - Europa 1.161
AS - Asia 727
SA - Sud America 89
AF - Africa 5
Continente sconosciuto - Info sul continente non disponibili 4
Totale 5.194
Nazione #
US - Stati Uniti d'America 3.197
IT - Italia 393
CN - Cina 261
SG - Singapore 249
UA - Ucraina 212
RU - Federazione Russa 178
VN - Vietnam 96
SE - Svezia 91
BR - Brasile 84
IE - Irlanda 77
DE - Germania 73
TR - Turchia 59
FI - Finlandia 46
EE - Estonia 38
KR - Corea 34
GB - Regno Unito 14
HK - Hong Kong 10
NL - Olanda 10
BG - Bulgaria 8
CA - Canada 8
IN - India 7
FR - Francia 5
AR - Argentina 4
CZ - Repubblica Ceca 4
EU - Europa 4
IL - Israele 4
MX - Messico 3
CH - Svizzera 2
ES - Italia 2
IQ - Iraq 2
MK - Macedonia 2
NO - Norvegia 2
PH - Filippine 2
RO - Romania 2
AT - Austria 1
BD - Bangladesh 1
CM - Camerun 1
EC - Ecuador 1
EG - Egitto 1
JO - Giordania 1
JP - Giappone 1
MA - Marocco 1
PL - Polonia 1
SN - Senegal 1
ZA - Sudafrica 1
Totale 5.194
Città #
Ann Arbor 870
Woodbridge 386
Chandler 366
Houston 267
Jacksonville 267
Princeton 204
Wilmington 191
Singapore 99
Dong Ket 95
Salerno 81
Dublin 77
Ashburn 65
Izmir 57
Nanjing 51
Andover 49
Beijing 49
Boardman 42
Pellezzano 40
Dearborn 38
Moscow 38
Tallinn 38
Hebei 24
Mestre 21
Fairfield 16
Changsha 15
Shenyang 15
Nanchang 14
Jiaxing 13
Naples 12
Norwalk 12
Düsseldorf 11
Jinan 11
Redwood City 11
Tianjin 11
Hong Kong 8
Falls Church 7
Indiana 7
Ottawa 7
Seattle 7
Washington 7
Los Angeles 6
Munich 6
Shanghai 6
Zhengzhou 6
Fisciano 5
Guangzhou 5
Pune 5
Rome 5
Sarno 5
Torino 5
Venezia 5
Amsterdam 4
Belo Horizonte 4
Dallas 4
New York 4
São Bernardo do Campo 4
Warrington 4
Afragola 3
Brasília 3
Brno 3
Cambridge 3
Cormano 3
Helsinki 3
Mercato San Severino 3
Mexico 3
Milan 3
Nettuno 3
Nocera Inferiore 3
Rio de Janeiro 3
San Francisco 3
Siena 3
Spinea 3
São Paulo 3
Taizhou 3
Tappahannock 3
Agropoli 2
Alvorada 2
Angri 2
Bologna 2
Brumadinho 2
Caianello 2
Domicella 2
Florence 2
Fremont 2
Girona 2
Groningen 2
Leawood 2
London 2
Lucca 2
Maceió 2
Marília 2
Mumbai 2
Napoli 2
Ningbo 2
Nuremberg 2
Pavia 2
Piracicaba 2
Ponte San Nicolò 2
Rende 2
San Diego 2
Totale 3.786
Nome #
1,3-Cycloaddition of nitrile oxides in ionic liquids. An easier route to 3-carboxy isoxazolines, potential constrained glutamic acid analogues. 277
Benzodiazepine Scaffold as Drug-like Molecular Simplification of FR235222: A Chemical Tool for Exploring HDAC Inhibition 140
Investigating the Neuroprotective Effects of Turmeric Extract: Structural Interactions of β-Amyloid Peptide with Single Curcuminoids 138
TRYPTOPHAN-BASED LINEAR DIPEPTIDES AND 1,4-DIKETOPIPERAZINES AS SIMPLIFIED SCAFFOLDS OF THE NATURAL CYCLOTETRAPEPTIDE FR235222 132
Gentamicina: derivatizzazione molecolare per migliorare la maneggevolezza sintetica e la farmacocinetica 127
TARGETING STAT3 IN CANCER INHIBITION 123
Fast determination of underivatized gentamicin C components and impurities by LC-MS using a porous graphitic carbon stationary phase 118
Build/couple/pair strategy: From nonchiral molecules to unbiased scaffolds, a methodological approach for the optimization of microwave-assisted intra-molecular Diels-Alder reaction of furans 116
The isoprenoid derivative N6-benzyladenosine (CM223) exerts antitumor effect in glioma patient-derived primary cells through the mevalonate pathway 113
Design and Synthesis of cyclopeptide analogues of the potent Histone deacetylase inhibitor FR235222 111
Sintesi di derivati SAHA-like utilizzati per indagare sulla selettività verso le diverse isoforme HDAC 108
Is it time to integrate sex and gender into drug design and development? 108
SYNTHESIS AND BIOLOGICAL EVALUATION OF SMALL MOLECULES DERIVATIVES OF THE NATURAL HISTONE DEACETYLASE INHIBITOR FR235222 107
Synthesis of Heterocycles via Microwave-Assisted Cycloadditions and Cyclocondensations 106
Facile Baeyer–Villiger oxidation of cyclic ketones: conventional versus microwave-assisted approach 105
Chemistry and biology of anti-inflammatory marine natural products: molecules interfering with cyclooxygenase, NF-κB and other unidentified targets 102
Epoxidation of 17-oxo-15,16-methylene steroids with sulfoxonium ylides 102
Molecular modeling studies toward the structural optimization of new cyclopeptide-based HDAC inhibitors modeled on the natural product FR235222 101
Histone deacetylase inhibitors in the treatment of cancer: overview and perspectives 101
A serum nuclear magnetic resonance-based metabolomic signature of antiphospholipid syndrome 101
STEROIDAL HYDROXAMIC ACID DERIVATIVES: A STRUCTURALLY NOVEL CLASS OF HDAC INHIBITORS 100
Solid-Phase Synthesis of Conformationally Constrained Peptidomimetics Based on a 3,6-Disubstituted-1,4-diazepan-2,5-dione Core 99
Oxime amides as a novel zinc binding group in histone deacetylase inhibitors: synthesis, biological activity, and computational evaluation 98
Total Synthesis, NMR Solution Structure, and Binding Model of the Potent Histone Deacetylase Inhibitor FR235222 97
STRUCTURAL FEATURES OF PEPTIDES DERIVED FROM FELINE IMMUNODEFICIENCY VIRUS TM-GLYCOPROTEIN 96
Identification of CM223 as a new ligand of farnesyl pyrophosphate synthase with improved antiglioma action 95
Histone deacetylase inhibitor FR235222 sensitizes human prostate adenocarcinoma cells to apoptosis through up-regulation of annexin A1. 93
A simple procedure for the transformation of L-glutamic acid into the corresponding γ-aldehyde 93
Transformation of Glutamic Acid into (S)-Benzyl 2-(dibenzylamino)-6-(dimethoxyphosphoryl)-5-oxohexanoate for a Convenient Access to 5-Substituted Prolines 91
N-thioalkylcarbazoles derivatives as new anti-proliferative agents: synthesis, characterisation and molecular mechanism evaluation 91
Colorimetric tools for solid-phase organic synthesis 88
β-Amyloid-acetylcholine molecular interaction: New role of cholinergic mediators in anti-Alzheimer therapy? 87
Synthesis of 2-Amino-8-oxodecanoic Acids (Aodas) Present in Natural Histone Deacetylase Inhibitors. 86
Synthesis and application in SPPS of a stable amino acid isoster of palmitoyl cysteine 85
Microwaves enhance cyclisation of tetrapeptides 82
Total Synthesis and Structural Elucidation of Azaspiracid-1. Construction of Key Building Blocks for Originally Proposed Structure. 81
Synthesis, structural aspects and cytotoxicity of the natural cyclopeptides yunnanins A, C and phakellistatins 1, 10 81
Ionic Liquid as a Suitable Phase for Multistep Parallel Synthesis of an Array of Isoxazolines 78
Sensible Improvements Induced by Ionic Liquids in the Reaction of Modified Carbasugars with Bases for the Building of Constrained Carbanucleosides 78
Downregulation of Hypoxia-related Responses by Novel Antitumor Histone Deacetylase Inhibitors in MDAMB231 Breast Cancer Cells 78
Synthesis of Enantiopure 7-Substituted Azepane-2-Carboxylic Acids as Templates for Conformationally Constrained Peptidomimetics 78
Developing molecular diversity in the construction of a family of bicyclic isoxazolines scaffolds: Control of regio-and diastereoselectivities 75
Skeletally Diverse Small Molecules Using a Build/Couple/Pair Strategy 74
Specific Targeting Highly Conserved Residues in the HIV-1 Reverse Transcriptase Primer Grip Region. Design, Synthesis, and Biological Evaluation of Novel, Potent, and Broad Spectrum NNRTIs with Antiviral Activity 69
Chemistry and Biology of Chromatin Remodeling Agents: State of Art and Future Perspectives of HDAC Inhibitors 67
Effects of FR235222, a novel HDAC inhibitor, in proliferation and apoptosis of human leukaemia cell lines: role of annexin A1 66
Synthesis of kainoids via a highly stereoselective hydroformylation of kainic acid. 64
Synthesis and biological evaluation of Santacruzamate-A based analogues 64
LGP1, a histone deacetylase inhibitor analogue of FR235222, sensitizes promyelocytic leukemia U937 cells to TRAIL-mediated apoptosis 62
Ganoderma lucidum ethanol extracts enhance re-epithelialization and prevent keratinocytes from free-radical injury 59
Total Synthesis and Biological Evaluation of Halipeptins A and D and Analogues. 58
Histone Deacetylase Inhibitors in the Treatment of Hematological Malignancies 57
NMR for screening and a biochemical assay: Identification of new FPPS inhibitors exerting anticancer activity 52
Saliva of patients affected by salivary gland tumour: An NMR metabolomics analysis 50
Discovery and Optimization of Indoline-Based Compounds as Dual 5-LOX/sEH Inhibitors: In Vitro and In Vivo Anti-Inflammatory Characterization 40
Fabrication of Novel Bio-Composites Based on Rice Milk for the Delivery of Capsaicinoids as Green Herbicides against Cynodon dactylon Weed 38
Cocoa Extract Provides Protection against 6-OHDA Toxicity in SH-SY5Y Dopaminergic Neurons by Targeting PERK 38
A New Approach to Supramolecular Structure Determination in Pharmaceutical Preparation of Self-Assembling Peptides: A Case Study of Lanreotide Autogel 37
Towards an improvement of anticancer activity of benzyl adenosine analogs 28
Structural analysis of a simplified model reproducing SARS-CoV-2 S RBD/ACE2 binding site 25
Salicylic Acid Release from Syndiotactic Polystyrene Staple Fibers 22
Structural analysis of a simplified model reproducing SARS-CoV-2 S RBD/ACE2 binding site 19
Bioelectrospun fibers loaded with Ganoderma lucidum green extracts as a novel bio/medical patch for wound healing applications 14
NANOPOROUS POLYMERS FOR MEDICAL AND COSMECEUTICAL APPLICATIONS 6
Totale 5.375
Categoria #
all - tutte 17.604
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 17.604


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/202083 0 0 0 0 0 0 0 0 0 0 77 6
2020/2021498 7 44 46 9 72 23 54 5 50 7 60 121
2021/2022410 1 1 1 12 34 17 8 20 57 42 62 155
2022/2023738 59 74 12 138 95 152 1 65 101 2 28 11
2023/2024261 28 46 13 9 16 41 16 9 8 17 14 44
2024/2025661 36 8 14 91 25 91 153 48 131 53 11 0
Totale 5.375