RODRIQUEZ, Manuela
 Distribuzione geografica
Continente #
AS - Asia 6.086
NA - Nord America 3.726
EU - Europa 1.328
SA - Sud America 212
AF - Africa 20
Continente sconosciuto - Info sul continente non disponibili 5
OC - Oceania 3
Totale 11.380
Nazione #
HK - Hong Kong 5.031
US - Stati Uniti d'America 3.678
IT - Italia 419
SG - Singapore 388
CN - Cina 346
UA - Ucraina 213
BR - Brasile 192
RU - Federazione Russa 182
DE - Germania 123
VN - Vietnam 122
SE - Svezia 97
IE - Irlanda 77
TR - Turchia 67
FI - Finlandia 58
KR - Corea 43
GB - Regno Unito 42
EE - Estonia 38
IN - India 29
CA - Canada 25
MX - Messico 20
PL - Polonia 18
JP - Giappone 14
NL - Olanda 13
AR - Argentina 12
ES - Italia 11
BG - Bulgaria 8
ZA - Sudafrica 8
BD - Bangladesh 7
FR - Francia 6
CH - Svizzera 5
CZ - Repubblica Ceca 5
IL - Israele 5
EU - Europa 4
ID - Indonesia 4
IQ - Iraq 4
MY - Malesia 4
TH - Thailandia 4
EG - Egitto 3
MK - Macedonia 3
UZ - Uzbekistan 3
AE - Emirati Arabi Uniti 2
AT - Austria 2
CM - Camerun 2
DZ - Algeria 2
EC - Ecuador 2
LT - Lituania 2
MA - Marocco 2
NO - Norvegia 2
PE - Perù 2
PH - Filippine 2
PK - Pakistan 2
RO - Romania 2
SA - Arabia Saudita 2
AF - Afghanistan, Repubblica islamica di 1
AU - Australia 1
BF - Burkina Faso 1
CI - Costa d'Avorio 1
CO - Colombia 1
DO - Repubblica Dominicana 1
GP - Guadalupe 1
JO - Giordania 1
KH - Cambogia 1
KW - Kuwait 1
LA - Repubblica Popolare Democratica del Laos 1
NP - Nepal 1
PA - Panama 1
PF - Polinesia Francese 1
PS - Palestinian Territory 1
PW - Palau 1
PY - Paraguay 1
RS - Serbia 1
SK - Slovacchia (Repubblica Slovacca) 1
SN - Senegal 1
UY - Uruguay 1
VE - Venezuela 1
XK - ???statistics.table.value.countryCode.XK??? 1
Totale 11.380
Città #
Hong Kong 5.021
Ann Arbor 870
Woodbridge 386
Chandler 366
Houston 271
Jacksonville 267
Princeton 204
Wilmington 191
Dallas 177
Singapore 137
Ashburn 132
Dong Ket 95
Salerno 82
Dublin 77
Beijing 74
Izmir 57
Munich 51
Nanjing 51
Andover 49
Boardman 42
Pellezzano 40
Dearborn 38
Moscow 38
Tallinn 38
Los Angeles 36
Hebei 24
New York 24
Mestre 21
São Paulo 21
Naples 19
Fairfield 16
Warsaw 16
Changsha 15
Shenyang 15
Nanchang 14
Tokyo 14
Chennai 13
Fisciano 13
Jiaxing 13
London 12
Norwalk 12
Santa Clara 12
Denver 11
Düsseldorf 11
Hanoi 11
Jinan 11
Redwood City 11
Tianjin 11
Turku 11
Brooklyn 10
Seattle 10
San Francisco 9
Johannesburg 8
Montreal 8
Stockholm 8
The Dalles 8
Amsterdam 7
Chicago 7
Falls Church 7
Indiana 7
Mexico City 7
Milan 7
Ottawa 7
Seoul 7
Washington 7
Atlanta 6
Belo Horizonte 6
Ho Chi Minh City 6
Nuremberg 6
Poplar 6
Shanghai 6
Zhengzhou 6
Guangzhou 5
Pune 5
Rio de Janeiro 5
Rome 5
Sarno 5
Torino 5
Venezia 5
Ankara 4
Bangkok 4
Boston 4
Columbus 4
Helsinki 4
Mumbai 4
Salvador 4
São Bernardo do Campo 4
Toronto 4
Warrington 4
Afragola 3
Betim 3
Biên Hòa 3
Brasília 3
Brno 3
Cambridge 3
Carney 3
Cormano 3
Curitiba 3
Ipatinga 3
Jakarta 3
Totale 9.415
Nome #
Histone deacetylase inhibitor FR235222 sensitizes human prostate adenocarcinoma cells to apoptosis through up-regulation of annexin A1. 1.263
Benzodiazepine Scaffold as Drug-like Molecular Simplification of FR235222: A Chemical Tool for Exploring HDAC Inhibition 610
N-thioalkylcarbazoles derivatives as new anti-proliferative agents: synthesis, characterisation and molecular mechanism evaluation 590
SYNTHESIS AND BIOLOGICAL EVALUATION OF SMALL MOLECULES DERIVATIVES OF THE NATURAL HISTONE DEACETYLASE INHIBITOR FR235222 551
Salicylic Acid Release from Syndiotactic Polystyrene Staple Fibers 525
Chemistry and biology of anti-inflammatory marine natural products: molecules interfering with cyclooxygenase, NF-κB and other unidentified targets 515
Bioelectrospun fibers loaded with Ganoderma lucidum green extracts as a novel bio/medical patch for wound healing applications 454
Downregulation of Hypoxia-related Responses by Novel Antitumor Histone Deacetylase Inhibitors in MDAMB231 Breast Cancer Cells 407
1,3-Cycloaddition of nitrile oxides in ionic liquids. An easier route to 3-carboxy isoxazolines, potential constrained glutamic acid analogues. 303
The isoprenoid derivative N6-benzyladenosine (CM223) exerts antitumor effect in glioma patient-derived primary cells through the mevalonate pathway 294
Sintesi di derivati SAHA-like utilizzati per indagare sulla selettività verso le diverse isoforme HDAC 236
NANOPOROUS POLYMERS FOR MEDICAL AND COSMECEUTICAL APPLICATIONS 229
Fast determination of underivatized gentamicin C components and impurities by LC-MS using a porous graphitic carbon stationary phase 215
Identification of CM223 as a new ligand of farnesyl pyrophosphate synthase with improved antiglioma action 186
TARGETING STAT3 IN CANCER INHIBITION 182
Facile Baeyer–Villiger oxidation of cyclic ketones: conventional versus microwave-assisted approach 173
A serum nuclear magnetic resonance-based metabolomic signature of antiphospholipid syndrome 167
Investigating the Neuroprotective Effects of Turmeric Extract: Structural Interactions of β-Amyloid Peptide with Single Curcuminoids 165
TRYPTOPHAN-BASED LINEAR DIPEPTIDES AND 1,4-DIKETOPIPERAZINES AS SIMPLIFIED SCAFFOLDS OF THE NATURAL CYCLOTETRAPEPTIDE FR235222 162
Gentamicina: derivatizzazione molecolare per migliorare la maneggevolezza sintetica e la farmacocinetica 150
Build/couple/pair strategy: From nonchiral molecules to unbiased scaffolds, a methodological approach for the optimization of microwave-assisted intra-molecular Diels-Alder reaction of furans 139
Design and Synthesis of cyclopeptide analogues of the potent Histone deacetylase inhibitor FR235222 133
STRUCTURAL FEATURES OF PEPTIDES DERIVED FROM FELINE IMMUNODEFICIENCY VIRUS TM-GLYCOPROTEIN 123
Is it time to integrate sex and gender into drug design and development? 119
STEROIDAL HYDROXAMIC ACID DERIVATIVES: A STRUCTURALLY NOVEL CLASS OF HDAC INHIBITORS 117
Synthesis of Heterocycles via Microwave-Assisted Cycloadditions and Cyclocondensations 117
Epoxidation of 17-oxo-15,16-methylene steroids with sulfoxonium ylides 116
Effects of FR235222, a novel HDAC inhibitor, in proliferation and apoptosis of human leukaemia cell lines: role of annexin A1 116
Solid-Phase Synthesis of Conformationally Constrained Peptidomimetics Based on a 3,6-Disubstituted-1,4-diazepan-2,5-dione Core 113
Histone deacetylase inhibitors in the treatment of cancer: overview and perspectives 113
A simple procedure for the transformation of L-glutamic acid into the corresponding γ-aldehyde 110
Colorimetric tools for solid-phase organic synthesis 110
Total Synthesis, NMR Solution Structure, and Binding Model of the Potent Histone Deacetylase Inhibitor FR235222 109
Structural analysis of a simplified model reproducing SARS-CoV-2 S RBD/ACE2 binding site 107
Molecular modeling studies toward the structural optimization of new cyclopeptide-based HDAC inhibitors modeled on the natural product FR235222 106
β-Amyloid-acetylcholine molecular interaction: New role of cholinergic mediators in anti-Alzheimer therapy? 104
A New Approach to Supramolecular Structure Determination in Pharmaceutical Preparation of Self-Assembling Peptides: A Case Study of Lanreotide Autogel 103
Oxime amides as a novel zinc binding group in histone deacetylase inhibitors: synthesis, biological activity, and computational evaluation 102
Synthesis and biological evaluation of Santacruzamate-A based analogues 102
Transformation of Glutamic Acid into (S)-Benzyl 2-(dibenzylamino)-6-(dimethoxyphosphoryl)-5-oxohexanoate for a Convenient Access to 5-Substituted Prolines 100
Synthesis of 2-Amino-8-oxodecanoic Acids (Aodas) Present in Natural Histone Deacetylase Inhibitors. 97
Total Synthesis and Structural Elucidation of Azaspiracid-1. Construction of Key Building Blocks for Originally Proposed Structure. 94
NMR for screening and a biochemical assay: Identification of new FPPS inhibitors exerting anticancer activity 94
Microwaves enhance cyclisation of tetrapeptides 93
Synthesis and application in SPPS of a stable amino acid isoster of palmitoyl cysteine 91
Synthesis, structural aspects and cytotoxicity of the natural cyclopeptides yunnanins A, C and phakellistatins 1, 10 91
Sensible Improvements Induced by Ionic Liquids in the Reaction of Modified Carbasugars with Bases for the Building of Constrained Carbanucleosides 89
Ionic Liquid as a Suitable Phase for Multistep Parallel Synthesis of an Array of Isoxazolines 88
Synthesis of Enantiopure 7-Substituted Azepane-2-Carboxylic Acids as Templates for Conformationally Constrained Peptidomimetics 88
Ganoderma lucidum ethanol extracts enhance re-epithelialization and prevent keratinocytes from free-radical injury 87
Developing molecular diversity in the construction of a family of bicyclic isoxazolines scaffolds: Control of regio-and diastereoselectivities 85
Chemistry and Biology of Chromatin Remodeling Agents: State of Art and Future Perspectives of HDAC Inhibitors 85
Skeletally Diverse Small Molecules Using a Build/Couple/Pair Strategy 82
Cocoa Extract Provides Protection against 6-OHDA Toxicity in SH-SY5Y Dopaminergic Neurons by Targeting PERK 78
Histone Deacetylase Inhibitors in the Treatment of Hematological Malignancies 76
Specific Targeting Highly Conserved Residues in the HIV-1 Reverse Transcriptase Primer Grip Region. Design, Synthesis, and Biological Evaluation of Novel, Potent, and Broad Spectrum NNRTIs with Antiviral Activity 76
Synthesis of kainoids via a highly stereoselective hydroformylation of kainic acid. 74
Discovery and Optimization of Indoline-Based Compounds as Dual 5-LOX/sEH Inhibitors: In Vitro and In Vivo Anti-Inflammatory Characterization 73
Saliva of patients affected by salivary gland tumour: An NMR metabolomics analysis 72
LGP1, a histone deacetylase inhibitor analogue of FR235222, sensitizes promyelocytic leukemia U937 cells to TRAIL-mediated apoptosis 70
Fabrication of Novel Bio-Composites Based on Rice Milk for the Delivery of Capsaicinoids as Green Herbicides against Cynodon dactylon Weed 68
Total Synthesis and Biological Evaluation of Halipeptins A and D and Analogues. 65
Towards an improvement of anticancer activity of benzyl adenosine analogs 55
Structural analysis of a simplified model reproducing SARS-CoV-2 S RBD/ACE2 binding site 54
Totale 11.561
Categoria #
all - tutte 28.662
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 28.662


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021392 0 0 0 0 72 23 54 5 50 7 60 121
2021/2022410 1 1 1 12 34 17 8 20 57 42 62 155
2022/2023738 59 74 12 138 95 152 1 65 101 2 28 11
2023/2024261 28 46 13 9 16 41 16 9 8 17 14 44
2024/2025899 36 8 14 91 25 91 153 48 131 53 126 123
2025/20265.948 1.310 2.327 1.850 276 185 0 0 0 0 0 0 0
Totale 11.561