UniSa - IRIS Institutional Research Information System

LAURO, Gianluigi
 Distribuzione geografica
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Continente #
AS - Asia 10.717
NA - Nord America 3.779
EU - Europa 1.475
SA - Sud America 479
AF - Africa 70
Continente sconosciuto - Info sul continente non disponibili 4
OC - Oceania 2
Totale 16.526
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Nazione #
HK - Hong Kong 8.900
US - Stati Uniti d'America 3.677
SG - Singapore 879
IT - Italia 531
BR - Brasile 392
CN - Cina 367
RU - Federazione Russa 245
VN - Vietnam 228
DE - Germania 189
UA - Ucraina 109
IE - Irlanda 81
TR - Turchia 68
IN - India 66
GB - Regno Unito 59
KR - Corea 56
CA - Canada 53
SE - Svezia 52
FI - Finlandia 46
AR - Argentina 39
JP - Giappone 38
MX - Messico 36
NL - Olanda 31
AT - Austria 27
ZA - Sudafrica 25
ID - Indonesia 23
PL - Polonia 22
BD - Bangladesh 21
DZ - Algeria 21
ES - Italia 20
CZ - Repubblica Ceca 17
FR - Francia 16
IQ - Iraq 16
PK - Pakistan 14
CO - Colombia 12
EC - Ecuador 12
MA - Marocco 8
PY - Paraguay 7
CH - Svizzera 6
CL - Cile 5
UZ - Uzbekistan 5
BE - Belgio 4
IL - Israele 4
RO - Romania 4
SA - Arabia Saudita 4
UY - Uruguay 4
VE - Venezuela 4
AZ - Azerbaigian 3
DK - Danimarca 3
EG - Egitto 3
EU - Europa 3
GT - Guatemala 3
HU - Ungheria 3
PE - Perù 3
TN - Tunisia 3
AE - Emirati Arabi Uniti 2
AL - Albania 2
BH - Bahrain 2
DO - Repubblica Dominicana 2
GA - Gabon 2
GE - Georgia 2
IR - Iran 2
JM - Giamaica 2
JO - Giordania 2
KE - Kenya 2
KZ - Kazakistan 2
LT - Lituania 2
LU - Lussemburgo 2
NG - Nigeria 2
NI - Nicaragua 2
NP - Nepal 2
A2 - ???statistics.table.value.countryCode.A2??? 1
AM - Armenia 1
AU - Australia 1
BG - Bulgaria 1
CU - Cuba 1
CY - Cipro 1
GN - Guinea 1
GY - Guiana 1
KI - Kiribati 1
LB - Libano 1
LC - Santa Lucia 1
LK - Sri Lanka 1
MC - Monaco 1
ML - Mali 1
MN - Mongolia 1
OM - Oman 1
PA - Panama 1
PS - Palestinian Territory 1
PT - Portogallo 1
QA - Qatar 1
SK - Slovacchia (Repubblica Slovacca) 1
SN - Senegal 1
SY - Repubblica araba siriana 1
TH - Thailandia 1
TT - Trinidad e Tobago 1
TW - Taiwan 1
ZM - Zambia 1
Totale 16.526
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Città #
Hong Kong 8.887
Dallas 689
Ann Arbor 558
Singapore 441
Chandler 326
Ashburn 243
Princeton 198
Woodbridge 151
Wilmington 145
Jacksonville 142
San Jose 139
Salerno 96
Munich 84
Dublin 80
Beijing 76
Los Angeles 71
Houston 69
Ho Chi Minh City 68
Naples 66
Izmir 52
Hanoi 43
Moscow 43
Fisciano 42
New York 41
São Paulo 39
Dong Ket 38
The Dalles 38
Tokyo 35
Andover 33
Montreal 32
Turku 28
Dearborn 26
Nanjing 26
Pellezzano 26
Columbus 23
Nuremberg 22
Brooklyn 21
Johannesburg 21
Boardman 20
Denver 20
Santa Clara 19
Warsaw 18
Chennai 17
Orem 17
Redwood City 16
Seattle 16
Brno 15
Chengdu 14
Phoenix 14
Stockholm 14
Council Bluffs 13
London 13
Mexico City 13
Afragola 12
Belo Horizonte 12
Boston 12
Vienna 12
Washington 12
Amsterdam 11
Fairfield 11
Frankfurt am Main 11
Jiaxing 11
Nanchang 11
Seoul 11
Curitiba 10
Lucca 10
Mestre 10
Milan 10
Poplar 10
Atlanta 9
Campinas 9
Chicago 9
Düsseldorf 9
Hải Dương 9
Pune 9
Da Nang 8
El Hadjira 8
Haiphong 8
Jakarta 8
Manchester 8
Rome 8
Sarno 8
Shanghai 8
Shenyang 8
West Jordan 8
Hebei 7
Jinan 7
Napoli 7
New Delhi 7
Ninh Bình 7
Tianjin 7
Chandigarh 6
Fes 6
Mumbai 6
Norwalk 6
Ortona 6
Redondo Beach 6
San Francisco 6
Toronto 6
Uster 6
Totale 13.803
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Nome #
Predicting PROTAC-mediated ternary complex structures through in silico approaches 2.206
A Combinatorial Virtual Screening Approach Driving the Synthesis of 2,4-Thiazolidinedione-Based Molecules as New Dual mPGES-1/5-LO Inhibitors 1.106
Inhibition of Microsomal Prostaglandin E2 Synthase 1: focused design of new anti-inflammatory and anti-cancer drugs 923
Protein Preparation Automatic Protocol for High-Throughput Inverse Virtual Screening: Accelerating the Target Identification by Computational Methods 587
New TRPM8 blockers exert anticancer activity over castration-resistant prostate cancer models 563
Inverse Virtual Screening for the rapid re-evaluation of the presumed biological safe profile of natural products. The case of steviol from Stevia rebaudiana glycosides on farnesoid X receptor (FXR) 543
In Silico Design, Chemical Synthesis, Biophysical and in Vitro Evaluation for the Identification of 1-Ethyl-1H-Pyrazolo[3,4-b]Pyridine-Based BRD9 Binders 507
Target identification by structure-based computational approaches: Recent advances and perspectives 450
Phytochemical investigation of Cannabis sativa: Isolation and structure determination of spiroindans 420
Exploration of TRPM8 Binding Sites by β-Carboline-Based Antagonists and Their in Vitro Characterization and in Vivo Analgesic Activities 393
Identification of Novel Bromodomain-Containing Protein 4 (BRD4) Binders through 3D Pharmacophore-Based Repositioning Screening Campaign 378
Insights into the ligand binding to bromodomain‐containing protein 9 (BRD9): A guide to the selection of potential binders by computational methods 306
Giffonins J-P, Highly Hydroxylated Cyclized Diarylheptanoids from the Leaves of Corylus avellana Cultivar "Tonda di Giffoni" 289
PharmaCore: The Automatic Generation of 3D Structure-Based Pharmacophore Models from Protein/Ligand Complexes 279
Investigation analysis of the phytochemical composition of Laurus nobilis L. leaves essential oil: a study of the antioxidant and anti-inflammatory properties using a combination of in vitro and in silico methods 249
9H-purine scaffold reveals induced-fit pocket plasticity of the BRD9 bromodomain 232
Essential Oils of Laurus nobilis L.: From Chemical Analysis to In Silico Investigation of Anti-Inflammatory Activity by Soluble Epoxide Hydrolase (sEH) Inhibition 230
Identification of a dual acting SARS-CoV-2 proteases inhibitor through in silico design and step-by-step biological characterization 206
Structural Evidence ofN6-Isopentenyladenosine As a New Ligand of Farnesyl Pyrophosphate Synthase 191
Bissubvilides A and B, Cembrane-capnosane heterodimers from the soft coral sarcophyton subviride 177
Structural Insights for the Optimization of Dihydropyrimidin-2(1H)-one Based mPGES-1 Inhibitors 170
Exploration of the dihydropyrimidine scaffold for the development of new potential anti-inflammatory agents blocking prostaglandin E2 synthase-1 enzyme (mPGES-1) 168
Chemical proteomics reveals HSP70 1A as a target for the anticancer diterpene oridonin in Jurkat cells 161
Plakilactones from the marine sponge Plakinastrella mamillaris. Discovery of a new class of marine ligands of peroxisome proliferator-activated receptor γ 156
Biological Profile of Two Gentiana lutea L. Metabolites Using Computational Approaches and In Vitro Tests 152
Oxygenated polyketides from plakinastrella mamillaris as a new chemotype of PXR agonists 151
Identification of novel microsomal prostaglandin E2 synthase-1 (mPGES-1) lead inhibitors from Fragment Virtual Screening 145
Anti-inflammatory trends of new benzimidazole derivatives 133
Inhibition of Wnt/β-Catenin pathway and Histone acetyltransferase activity by Rimonabant: a therapeutic target for colon cancer 132
Discovery and Synthesis of Namalide Reveals a New Anabaenopeptin Scaffold and Peptidase Inhibitor 131
Targeting Microsomal Prostaglanding E2 Synthase 1 for the Development of new potential Anti-Inflammatory Drugs 127
Cyclic Diarylheptanoids from Corylus avellana Green Leafy Covers: Determination of Their Absolute Configurations and Evaluation of Their Antioxidant and Antimicrobial Activities 121
Identification of 2,4,5-trisubstituted-2,4-dihydro-3H-1,2,4-triazol-3-one-based small molecules as selective BRD9 binders 116
Virtual screening of 3-(1H-1,2,3-triazol-1-yl)piperidine-2,6-dione-based compounds as new potential Cereblon modulators amenable for targeted protein degradation 116
Chemistry and Selective Tumor Cell Growth Inhibitory Activity of Polyketides from the South China Sea Sponge Plakortis sp 115
Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19) 115
Hyalachelins A–C, Unusual Siderophores Isolated from the Terrestrial MyxobacteriumHyalangium minutum 114
Discovery and synthesis of the first selective BAG domain modulator of BAG3 as an attractive candidate for the development of a new class of chemotherapeutics 112
Structure-Based Design of Microsomal Prostaglandin E2 Synthase-1 (mPGES-1) Inhibitors using a Virtual Fragment Growing Optimization Scheme 110
The plant diterpene epoxysiderol targets Hsp70 in cancer cells, affecting its ATPase activity and reducing its translocation to plasma membrane 110
Dihydroaurones and Isoflavan Derivatives from the Roots of Glycyrrhiza asymmetrica 109
Modification in the side chain of solomonsterol A: discovery of cholestan disulfate as a potent pregnane-X-receptor agonist 108
DFT/NMR Approach for the Configuration Assignment of Groups of Stereoisomers by the Combination and Comparison of Experimental and Predicted Sets of Data 104
Chemoproteomics Reveals USP5 (Ubiquitin Carboxyl-Terminal Hydrolase 5) as Promising Target of the Marine Polyketide Gracilioether A 103
2-Substituted 1,5-benzothiazepine-based HDAC inhibitors exert anticancer activities on human solid and acute myeloid leukemia cell lines 102
Pharmacological evaluation and docking studies of α,β-unsaturated carbonyl based synthetic compounds as inhibitors of secretory phospholipase A2, cyclooxygenases, lipoxygenase and proinflammatory cytokines 102
New Steroids with a Rearranged Skeleton as (h)P300 Inhibitors from the SpongeTheonella swinhoei 101
Corylus avellana: A Source of Diarylheptanoids With α-Glucosidase Inhibitory Activity Evaluated by in vitro and in silico Studies 100
Inverse Virtual Screening of Antitumor Targets: Pilot Study on a Small Database of Natural Bioactive Compounds 98
Ring-Fused Cyclic Aminals from Tetrahydro-β-carboline-Based Dipeptide Compounds 98
Inverse Virtual Screening allows the discovery of the biological activity of natural compounds 97
Glucopyranosylbianthrones from the Algerian Asphodelus tenuifolius: Structural Insights and Biological Evaluation on Melanoma Cancer Cells 94
Identification of an indol-based multi-target kinase inhibitor through phenotype screening and target fishing using inverse virtual screening approach 94
A Comprehensive In Vitro Characterization of a New Class of Indole-Based Compounds Developed as Selective Haspin Inhibitors 93
Tulongicin, an Antibacterial Tri-Indole Alkaloid from a Deep-Water Topsentia sp. Sponge 90
Addressing the Target Identification and Accelerating the Repositioning of Anti-Inflammatory/Anti-Cancer Organic Compounds by Computational Approaches 88
Novel para‐phenylenediamine‐based derivatives as Receptor Tyrosine Kinase‐like Orphan Receptor 1 (ROR1) Inhibitors: An in vitro preliminary characterization 87
Discovery of noscapine derivatives as potential β-tubulin inhibitors 87
Identification of the first-in-class dual inhibitor targeting BAG3 and HSP70 proteins to disrupt multiple chaperone pathways 83
6-Methylquinazolin-4(3H)-one Based Compounds as BRD9 Epigenetic Reader Binders: A Rational Combination of in silico Studies and Chemical Synthesis 83
Svetamycins A-G, Unusual Piperazic Acid-Containing Peptides from Streptomyces sp 82
In Silico, In Vitro, and In Vivo Analysis of Tanshinone IIA and Cryptotanshinone from Salvia miltiorrhiza as Modulators of Cyclooxygenase-2/mPGES-1/Endothelial Prostaglandin EP3 Pathway 81
Structural Refinement of 2,4-Thiazolidinedione Derivatives as New Anticancer Agents Able to Modulate the BAG3 Protein 79
Exploring the chemical space of functionalized [1,2,4]triazolo[4,3-a]quinoxaline-based compounds targeting the bromodomain of BRD9 79
Reranking docking poses using molecular simulations and approximate free energy methods 78
5-methyl-2-carboxamidepyrrole-based novel dual mPGES-1/sEH inhibitors as promising anticancer candidates 76
Giffonins, Antioxidant Diarylheptanoids from Corylus avellana, and Their Ability to Prevent Oxidative Changes in Human Plasma Proteins 74
Discovery of a Secalonic Acid Derivative from Aspergillus aculeatus, an Endophyte of Rosa damascena Mill., Triggers Apoptosis in MDA-MB-231 Triple Negative Breast Cancer Cells 73
Discovery of 3-hydroxy-3-pyrrolin-2-one-based mPGES-1 inhibitors using a multi-step virtual screening protocol 72
Repositioning of Quinazolinedione-Based Compounds on Soluble Epoxide Hydrolase (sEH) through 3D Structure-Based Pharmacophore Model-Driven Investigation 71
Elucidating the Relative and Absolute Configuration of Organic Compounds by Quantum Mechanical Approaches 71
Introducing structure-based three-dimensional pharmacophore models for accelerating the discovery of selective BRD9 binders 71
Isolation, Synthesis And Structure Determination Of Cannabidiol Derivatives And Their Cytotoxic Activities 70
Peptidomimetics as potent dual SARS-CoV-2 cathepsin-L and main protease inhibitors: In silico design, synthesis and pharmacological characterization 70
Unveiling the Potential Biological and Chemical Mechanism of Pergularia tomentosa Extracts by Liquid Chromatography‐Electrospray Ionisation‐High‐Resolution Tandem Mass Spectrometry, In‐Vitro and In‐Vivo Pharmacological Studies 68
Furazanopyrazine-based novel promising anticancer agents interfering with the eicosanoid biosynthesis pathways by dual mPGES-1 and sEH inhibition 67
Thiazolidin-4-one-based compounds interfere with the eicosanoid biosynthesis pathways by mPGES-1/sEH/5-LO multi-target inhibition 67
NMR Metabolomics and Chemometrics of Commercial Varieties of Phaseolus vulgaris L. Seeds from Italy and In Vitro Antioxidant and Antifungal Activity 65
Immunomodulatory Biscembranoids and Assignment of Their Relative and Absolute Configurations: Data Set Modulation in the Density Functional Theory/Nuclear Magnetic Resonance Approach 65
Untargeted Diversity-Oriented Synthesis for the Discovery of New Antitumor Agents: An Integrated Approach of Inverse Virtual Screening, Bioinformatics, and Omics for Target Deconvolution 61
Phytochemical Analysis of the Methanolic Extract and Essential Oil from Leaves of Industrial Hemp Futura 75 Cultivar: Isolation of a New Cannabinoid Derivative and Biological Profile Using Computational Approaches 61
Fatty Acid Synthase as Interacting Anticancer Target of the Terpenoid Myrianthic Acid Disclosed by MS-Based Proteomics Approaches 58
Total synthesis of the potent anti-inflammatory natural product solomonamide A along with structural revision and biological activity evaluation 58
Repositioning of Small Molecules through the Inverse Virtual Screening in silico Tool: Case of Benzothiazole-Based Inhibitors of Soluble Epoxide Hydrolase (sEH) 56
Chemical Profiling of Polar Lipids and the Polyphenolic Fraction of Commercial Italian Phaseolus Seeds by UHPLC-HRMS and Biological Evaluation 54
Identification of a New Promising BAG3 Modulator Featuring the Imidazopyridine Scaffold 52
A Classic Photochemical Approach Inducing an Unexpected Rearrangement: Exploring the Photoreactivity of Pentacyclic Triterpenic Acids 37
Extensive Molecular Dynamics Simulations Disclosed the Stability of mPGES-1 Enzyme and the Structural Role of Glutathione (GSH) Cofactor 34
Identification and Development of BRD9 Chemical Probes 34
Scabiosa atropurpurea: A rich source of iridoids with α-glucosidase inhibitory activity evaluated by in vitro and in silico studies 33
Identification of 2-Aminoacyl-1,3,4-thiadiazoles as Prostaglandin E2 and Leukotriene Biosynthesis Inhibitors 29
New techniques of molecular modelling and structural chemistry for the development of bioactive compounds 2
Totale 16.759
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Categoria #
all - tutte 40.261
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 40.261
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021241 0 0 0 0 0 0 54 10 76 9 40 52
2021/2022393 3 1 8 20 24 6 6 19 58 43 49 156
2022/2023740 58 77 19 115 76 142 12 72 95 5 43 26
2023/2024385 17 40 31 21 43 90 24 24 13 21 11 50
2024/20252.207 58 14 11 71 47 115 388 115 248 73 180 887
2025/202611.297 3.004 3.426 3.077 610 700 276 204 0 0 0 0 0
Totale 16.759