LAURO, Gianluigi
 Distribuzione geografica
Continente #
AS - Asia 10.189
NA - Nord America 3.513
EU - Europa 1.421
SA - Sud America 437
AF - Africa 57
Continente sconosciuto - Info sul continente non disponibili 4
OC - Oceania 2
Totale 15.623
Nazione #
HK - Hong Kong 8.873
US - Stati Uniti d'America 3.422
SG - Singapore 542
IT - Italia 510
BR - Brasile 370
CN - Cina 323
RU - Federazione Russa 244
DE - Germania 185
VN - Vietnam 151
UA - Ucraina 106
IE - Irlanda 81
TR - Turchia 67
IN - India 60
KR - Corea 55
SE - Svezia 50
CA - Canada 48
GB - Regno Unito 48
FI - Finlandia 46
JP - Giappone 35
MX - Messico 31
NL - Olanda 30
AR - Argentina 29
AT - Austria 26
DZ - Algeria 20
ID - Indonesia 20
PL - Polonia 20
ZA - Sudafrica 20
CZ - Repubblica Ceca 17
ES - Italia 17
BD - Bangladesh 16
FR - Francia 15
EC - Ecuador 11
CO - Colombia 10
PK - Pakistan 10
IQ - Iraq 8
MA - Marocco 8
CH - Svizzera 6
CL - Cile 5
UZ - Uzbekistan 5
BE - Belgio 4
PY - Paraguay 4
RO - Romania 4
SA - Arabia Saudita 4
AZ - Azerbaigian 3
EU - Europa 3
HU - Ungheria 3
PE - Perù 3
AE - Emirati Arabi Uniti 2
BH - Bahrain 2
DO - Repubblica Dominicana 2
EG - Egitto 2
GT - Guatemala 2
IL - Israele 2
JM - Giamaica 2
JO - Giordania 2
KE - Kenya 2
LU - Lussemburgo 2
NI - Nicaragua 2
UY - Uruguay 2
VE - Venezuela 2
A2 - ???statistics.table.value.countryCode.A2??? 1
AL - Albania 1
AM - Armenia 1
AU - Australia 1
BG - Bulgaria 1
CU - Cuba 1
CY - Cipro 1
DK - Danimarca 1
GE - Georgia 1
GN - Guinea 1
GY - Guiana 1
KI - Kiribati 1
KZ - Kazakistan 1
LB - Libano 1
LC - Santa Lucia 1
LT - Lituania 1
MC - Monaco 1
MN - Mongolia 1
NG - Nigeria 1
PA - Panama 1
PT - Portogallo 1
QA - Qatar 1
SK - Slovacchia (Repubblica Slovacca) 1
SN - Senegal 1
SY - Repubblica araba siriana 1
TN - Tunisia 1
TT - Trinidad e Tobago 1
TW - Taiwan 1
ZM - Zambia 1
Totale 15.623
Città #
Hong Kong 8.860
Dallas 689
Ann Arbor 558
Chandler 326
Ashburn 203
Princeton 198
Singapore 188
Woodbridge 151
Wilmington 145
Jacksonville 142
Salerno 90
Munich 84
Dublin 80
Beijing 76
Houston 68
Los Angeles 63
Naples 62
Izmir 52
Ho Chi Minh City 44
Moscow 43
Fisciano 41
Dong Ket 38
São Paulo 37
New York 36
Andover 33
Tokyo 32
Montreal 28
Turku 28
Dearborn 26
Hanoi 26
Nanjing 26
Pellezzano 26
Columbus 23
Nuremberg 22
The Dalles 21
Boardman 20
Brooklyn 20
Denver 18
Santa Clara 18
Johannesburg 16
Redwood City 16
Seattle 16
Warsaw 16
Brno 15
Chennai 13
Afragola 12
Belo Horizonte 12
Boston 12
Stockholm 12
Vienna 12
Washington 12
Fairfield 11
Jiaxing 11
Mexico City 11
Nanchang 11
Phoenix 11
Seoul 11
Amsterdam 10
Curitiba 10
Mestre 10
Milan 10
Chicago 9
Düsseldorf 9
Lucca 9
Orem 9
Pune 9
Atlanta 8
El Hadjira 8
Jakarta 8
London 8
Rome 8
Sarno 8
Shanghai 8
Shenyang 8
West Jordan 8
Campinas 7
Council Bluffs 7
Frankfurt am Main 7
Hebei 7
Jinan 7
Manchester 7
Napoli 7
New Delhi 7
Poplar 7
Tianjin 7
Chandigarh 6
Fes 6
Mumbai 6
Norwalk 6
Ortona 6
Redondo Beach 6
San Francisco 6
Uster 6
Ankara 5
Bogotá 5
Buenos Aires 5
Caivano 5
Cava de' Tirreni 5
Domicella 5
Guangzhou 5
Totale 13.181
Nome #
Predicting PROTAC-mediated ternary complex structures through in silico approaches 2.170
A Combinatorial Virtual Screening Approach Driving the Synthesis of 2,4-Thiazolidinedione-Based Molecules as New Dual mPGES-1/5-LO Inhibitors 1.101
Inhibition of Microsomal Prostaglandin E2 Synthase 1: focused design of new anti-inflammatory and anti-cancer drugs 913
Protein Preparation Automatic Protocol for High-Throughput Inverse Virtual Screening: Accelerating the Target Identification by Computational Methods 574
New TRPM8 blockers exert anticancer activity over castration-resistant prostate cancer models 555
Inverse Virtual Screening for the rapid re-evaluation of the presumed biological safe profile of natural products. The case of steviol from Stevia rebaudiana glycosides on farnesoid X receptor (FXR) 529
In Silico Design, Chemical Synthesis, Biophysical and in Vitro Evaluation for the Identification of 1-Ethyl-1H-Pyrazolo[3,4-b]Pyridine-Based BRD9 Binders 497
Target identification by structure-based computational approaches: Recent advances and perspectives 443
Phytochemical investigation of Cannabis sativa: Isolation and structure determination of spiroindans 415
Exploration of TRPM8 Binding Sites by β-Carboline-Based Antagonists and Their in Vitro Characterization and in Vivo Analgesic Activities 377
Identification of Novel Bromodomain-Containing Protein 4 (BRD4) Binders through 3D Pharmacophore-Based Repositioning Screening Campaign 372
Insights into the ligand binding to bromodomain‐containing protein 9 (BRD9): A guide to the selection of potential binders by computational methods 297
Giffonins J-P, Highly Hydroxylated Cyclized Diarylheptanoids from the Leaves of Corylus avellana Cultivar "Tonda di Giffoni" 277
PharmaCore: The Automatic Generation of 3D Structure-Based Pharmacophore Models from Protein/Ligand Complexes 268
Investigation analysis of the phytochemical composition of Laurus nobilis L. leaves essential oil: a study of the antioxidant and anti-inflammatory properties using a combination of in vitro and in silico methods 232
9H-purine scaffold reveals induced-fit pocket plasticity of the BRD9 bromodomain 224
Essential Oils of Laurus nobilis L.: From Chemical Analysis to In Silico Investigation of Anti-Inflammatory Activity by Soluble Epoxide Hydrolase (sEH) Inhibition 216
Identification of a dual acting SARS-CoV-2 proteases inhibitor through in silico design and step-by-step biological characterization 191
Structural Evidence ofN6-Isopentenyladenosine As a New Ligand of Farnesyl Pyrophosphate Synthase 184
Bissubvilides A and B, Cembrane-capnosane heterodimers from the soft coral sarcophyton subviride 169
Structural Insights for the Optimization of Dihydropyrimidin-2(1H)-one Based mPGES-1 Inhibitors 160
Exploration of the dihydropyrimidine scaffold for the development of new potential anti-inflammatory agents blocking prostaglandin E2 synthase-1 enzyme (mPGES-1) 156
Plakilactones from the marine sponge Plakinastrella mamillaris. Discovery of a new class of marine ligands of peroxisome proliferator-activated receptor γ 148
Biological Profile of Two Gentiana lutea L. Metabolites Using Computational Approaches and In Vitro Tests 145
Chemical proteomics reveals HSP70 1A as a target for the anticancer diterpene oridonin in Jurkat cells 144
Oxygenated polyketides from plakinastrella mamillaris as a new chemotype of PXR agonists 142
Identification of novel microsomal prostaglandin E2 synthase-1 (mPGES-1) lead inhibitors from Fragment Virtual Screening 138
Discovery and Synthesis of Namalide Reveals a New Anabaenopeptin Scaffold and Peptidase Inhibitor 126
Anti-inflammatory trends of new benzimidazole derivatives 123
Inhibition of Wnt/β-Catenin pathway and Histone acetyltransferase activity by Rimonabant: a therapeutic target for colon cancer 121
Targeting Microsomal Prostaglanding E2 Synthase 1 for the Development of new potential Anti-Inflammatory Drugs 115
Cyclic Diarylheptanoids from Corylus avellana Green Leafy Covers: Determination of Their Absolute Configurations and Evaluation of Their Antioxidant and Antimicrobial Activities 109
Chemistry and Selective Tumor Cell Growth Inhibitory Activity of Polyketides from the South China Sea Sponge Plakortis sp 108
Hyalachelins A–C, Unusual Siderophores Isolated from the Terrestrial MyxobacteriumHyalangium minutum 106
Modification in the side chain of solomonsterol A: discovery of cholestan disulfate as a potent pregnane-X-receptor agonist 103
Discovery and synthesis of the first selective BAG domain modulator of BAG3 as an attractive candidate for the development of a new class of chemotherapeutics 103
Identification of 2,4,5-trisubstituted-2,4-dihydro-3H-1,2,4-triazol-3-one-based small molecules as selective BRD9 binders 102
Dihydroaurones and Isoflavan Derivatives from the Roots of Glycyrrhiza asymmetrica 102
Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19) 101
Structure-Based Design of Microsomal Prostaglandin E2 Synthase-1 (mPGES-1) Inhibitors using a Virtual Fragment Growing Optimization Scheme 100
DFT/NMR Approach for the Configuration Assignment of Groups of Stereoisomers by the Combination and Comparison of Experimental and Predicted Sets of Data 98
The plant diterpene epoxysiderol targets Hsp70 in cancer cells, affecting its ATPase activity and reducing its translocation to plasma membrane 97
New Steroids with a Rearranged Skeleton as (h)P300 Inhibitors from the SpongeTheonella swinhoei 94
Corylus avellana: A Source of Diarylheptanoids With α-Glucosidase Inhibitory Activity Evaluated by in vitro and in silico Studies 93
Pharmacological evaluation and docking studies of α,β-unsaturated carbonyl based synthetic compounds as inhibitors of secretory phospholipase A2, cyclooxygenases, lipoxygenase and proinflammatory cytokines 92
Ring-Fused Cyclic Aminals from Tetrahydro-β-carboline-Based Dipeptide Compounds 92
2-Substituted 1,5-benzothiazepine-based HDAC inhibitors exert anticancer activities on human solid and acute myeloid leukemia cell lines 91
Inverse Virtual Screening of Antitumor Targets: Pilot Study on a Small Database of Natural Bioactive Compounds 90
Inverse Virtual Screening allows the discovery of the biological activity of natural compounds 88
Glucopyranosylbianthrones from the Algerian Asphodelus tenuifolius: Structural Insights and Biological Evaluation on Melanoma Cancer Cells 87
Identification of an indol-based multi-target kinase inhibitor through phenotype screening and target fishing using inverse virtual screening approach 85
Tulongicin, an Antibacterial Tri-Indole Alkaloid from a Deep-Water Topsentia sp. Sponge 85
Chemoproteomics Reveals USP5 (Ubiquitin Carboxyl-Terminal Hydrolase 5) as Promising Target of the Marine Polyketide Gracilioether A 83
A Comprehensive In Vitro Characterization of a New Class of Indole-Based Compounds Developed as Selective Haspin Inhibitors 81
Discovery of noscapine derivatives as potential β-tubulin inhibitors 80
Novel para‐phenylenediamine‐based derivatives as Receptor Tyrosine Kinase‐like Orphan Receptor 1 (ROR1) Inhibitors: An in vitro preliminary characterization 79
Virtual screening of 3-(1H-1,2,3-triazol-1-yl)piperidine-2,6-dione-based compounds as new potential Cereblon modulators amenable for targeted protein degradation 78
Svetamycins A-G, Unusual Piperazic Acid-Containing Peptides from Streptomyces sp 78
6-Methylquinazolin-4(3H)-one Based Compounds as BRD9 Epigenetic Reader Binders: A Rational Combination of in silico Studies and Chemical Synthesis 76
Addressing the Target Identification and Accelerating the Repositioning of Anti-Inflammatory/Anti-Cancer Organic Compounds by Computational Approaches 75
Reranking docking poses using molecular simulations and approximate free energy methods 74
Exploring the chemical space of functionalized [1,2,4]triazolo[4,3-a]quinoxaline-based compounds targeting the bromodomain of BRD9 74
Structural Refinement of 2,4-Thiazolidinedione Derivatives as New Anticancer Agents Able to Modulate the BAG3 Protein 71
Identification of the first-in-class dual inhibitor targeting BAG3 and HSP70 proteins to disrupt multiple chaperone pathways 69
Discovery of 3-hydroxy-3-pyrrolin-2-one-based mPGES-1 inhibitors using a multi-step virtual screening protocol 67
In Silico, In Vitro, and In Vivo Analysis of Tanshinone IIA and Cryptotanshinone from Salvia miltiorrhiza as Modulators of Cyclooxygenase-2/mPGES-1/Endothelial Prostaglandin EP3 Pathway 67
Giffonins, Antioxidant Diarylheptanoids from Corylus avellana, and Their Ability to Prevent Oxidative Changes in Human Plasma Proteins 66
Discovery of a Secalonic Acid Derivative from Aspergillus aculeatus, an Endophyte of Rosa damascena Mill., Triggers Apoptosis in MDA-MB-231 Triple Negative Breast Cancer Cells 64
Introducing structure-based three-dimensional pharmacophore models for accelerating the discovery of selective BRD9 binders 64
Isolation, Synthesis And Structure Determination Of Cannabidiol Derivatives And Their Cytotoxic Activities 63
Peptidomimetics as potent dual SARS-CoV-2 cathepsin-L and main protease inhibitors: In silico design, synthesis and pharmacological characterization 63
Unveiling the Potential Biological and Chemical Mechanism of Pergularia tomentosa Extracts by Liquid Chromatography‐Electrospray Ionisation‐High‐Resolution Tandem Mass Spectrometry, In‐Vitro and In‐Vivo Pharmacological Studies 62
Repositioning of Quinazolinedione-Based Compounds on Soluble Epoxide Hydrolase (sEH) through 3D Structure-Based Pharmacophore Model-Driven Investigation 60
Elucidating the Relative and Absolute Configuration of Organic Compounds by Quantum Mechanical Approaches 60
Immunomodulatory Biscembranoids and Assignment of Their Relative and Absolute Configurations: Data Set Modulation in the Density Functional Theory/Nuclear Magnetic Resonance Approach 59
Furazanopyrazine-based novel promising anticancer agents interfering with the eicosanoid biosynthesis pathways by dual mPGES-1 and sEH inhibition 58
Thiazolidin-4-one-based compounds interfere with the eicosanoid biosynthesis pathways by mPGES-1/sEH/5-LO multi-target inhibition 58
NMR Metabolomics and Chemometrics of Commercial Varieties of Phaseolus vulgaris L. Seeds from Italy and In Vitro Antioxidant and Antifungal Activity 58
5-methyl-2-carboxamidepyrrole-based novel dual mPGES-1/sEH inhibitors as promising anticancer candidates 57
Phytochemical Analysis of the Methanolic Extract and Essential Oil from Leaves of Industrial Hemp Futura 75 Cultivar: Isolation of a New Cannabinoid Derivative and Biological Profile Using Computational Approaches 53
Total synthesis of the potent anti-inflammatory natural product solomonamide A along with structural revision and biological activity evaluation 53
Untargeted Diversity-Oriented Synthesis for the Discovery of New Antitumor Agents: An Integrated Approach of Inverse Virtual Screening, Bioinformatics, and Omics for Target Deconvolution 48
Chemical Profiling of Polar Lipids and the Polyphenolic Fraction of Commercial Italian Phaseolus Seeds by UHPLC-HRMS and Biological Evaluation 44
Identification of a New Promising BAG3 Modulator Featuring the Imidazopyridine Scaffold 44
Fatty Acid Synthase as Interacting Anticancer Target of the Terpenoid Myrianthic Acid Disclosed by MS-Based Proteomics Approaches 43
Repositioning of Small Molecules through the Inverse Virtual Screening in silico Tool: Case of Benzothiazole-Based Inhibitors of Soluble Epoxide Hydrolase (sEH) 39
Scabiosa atropurpurea: A rich source of iridoids with α-glucosidase inhibitory activity evaluated by in vitro and in silico studies 30
Extensive Molecular Dynamics Simulations Disclosed the Stability of mPGES-1 Enzyme and the Structural Role of Glutathione (GSH) Cofactor 30
Identification and Development of BRD9 Chemical Probes 28
A Classic Photochemical Approach Inducing an Unexpected Rearrangement: Exploring the Photoreactivity of Pentacyclic Triterpenic Acids 26
Identification of 2-Aminoacyl-1,3,4-thiadiazoles as Prostaglandin E2 and Leukotriene Biosynthesis Inhibitors 26
Totale 15.856
Categoria #
all - tutte 38.294
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 38.294


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021282 0 0 0 0 27 14 54 10 76 9 40 52
2021/2022393 3 1 8 20 24 6 6 19 58 43 49 156
2022/2023740 58 77 19 115 76 142 12 72 95 5 43 26
2023/2024385 17 40 31 21 43 90 24 24 13 21 11 50
2024/20252.207 58 14 11 71 47 115 388 115 248 73 180 887
2025/202610.394 3.004 3.426 3.077 610 277 0 0 0 0 0 0 0
Totale 15.856