LAURO, Gianluigi
 Distribuzione geografica
Continente #
AS - Asia 10.015
NA - Nord America 3.349
EU - Europa 1.373
SA - Sud America 417
AF - Africa 53
Continente sconosciuto - Info sul continente non disponibili 4
OC - Oceania 2
Totale 15.213
Nazione #
HK - Hong Kong 8.871
US - Stati Uniti d'America 3.276
IT - Italia 489
SG - Singapore 437
BR - Brasile 354
CN - Cina 292
RU - Federazione Russa 243
DE - Germania 185
VN - Vietnam 144
UA - Ucraina 104
IE - Irlanda 81
TR - Turchia 61
KR - Corea 55
IN - India 54
SE - Svezia 47
FI - Finlandia 46
GB - Regno Unito 39
CA - Canada 38
JP - Giappone 29
NL - Olanda 29
AR - Argentina 27
AT - Austria 26
MX - Messico 23
DZ - Algeria 20
ID - Indonesia 19
CZ - Repubblica Ceca 17
ZA - Sudafrica 16
FR - Francia 15
ES - Italia 13
PL - Polonia 13
BD - Bangladesh 12
EC - Ecuador 10
CO - Colombia 9
MA - Marocco 8
IQ - Iraq 7
CH - Svizzera 6
PK - Pakistan 6
CL - Cile 5
UZ - Uzbekistan 5
BE - Belgio 4
PY - Paraguay 4
RO - Romania 4
SA - Arabia Saudita 4
AZ - Azerbaigian 3
EU - Europa 3
HU - Ungheria 3
PE - Perù 3
AE - Emirati Arabi Uniti 2
BH - Bahrain 2
DO - Repubblica Dominicana 2
EG - Egitto 2
GT - Guatemala 2
JM - Giamaica 2
JO - Giordania 2
KE - Kenya 2
LU - Lussemburgo 2
NI - Nicaragua 2
UY - Uruguay 2
VE - Venezuela 2
A2 - ???statistics.table.value.countryCode.A2??? 1
AL - Albania 1
AM - Armenia 1
AU - Australia 1
BG - Bulgaria 1
CU - Cuba 1
CY - Cipro 1
DK - Danimarca 1
GE - Georgia 1
GN - Guinea 1
GY - Guiana 1
IL - Israele 1
KI - Kiribati 1
KZ - Kazakistan 1
LB - Libano 1
LC - Santa Lucia 1
LT - Lituania 1
MC - Monaco 1
MN - Mongolia 1
NG - Nigeria 1
PA - Panama 1
PT - Portogallo 1
QA - Qatar 1
SK - Slovacchia (Repubblica Slovacca) 1
SN - Senegal 1
SY - Repubblica araba siriana 1
TN - Tunisia 1
TT - Trinidad e Tobago 1
TW - Taiwan 1
ZM - Zambia 1
Totale 15.213
Città #
Hong Kong 8.858
Dallas 687
Ann Arbor 558
Chandler 326
Princeton 198
Singapore 185
Ashburn 173
Woodbridge 151
Wilmington 145
Jacksonville 142
Salerno 89
Munich 84
Dublin 80
Beijing 66
Houston 65
Naples 54
Izmir 52
Los Angeles 45
Moscow 43
Fisciano 41
Ho Chi Minh City 39
Dong Ket 38
Andover 33
São Paulo 30
Turku 28
Dearborn 26
Nanjing 26
Pellezzano 26
Tokyo 26
Hanoi 25
Columbus 23
Montreal 23
New York 23
Nuremberg 22
The Dalles 21
Boardman 20
Brooklyn 16
Redwood City 16
Santa Clara 16
Brno 15
Seattle 15
Johannesburg 13
Afragola 12
Vienna 12
Washington 12
Belo Horizonte 11
Fairfield 11
Jiaxing 11
Nanchang 11
Seoul 11
Boston 10
Mestre 10
Amsterdam 9
Chennai 9
Chicago 9
Curitiba 9
Denver 9
Düsseldorf 9
Pune 9
Stockholm 9
Warsaw 9
El Hadjira 8
Jakarta 8
Mexico City 8
Milan 8
Phoenix 8
Rome 8
Sarno 8
Shanghai 8
Shenyang 8
West Jordan 8
Campinas 7
Council Bluffs 7
Frankfurt am Main 7
Hebei 7
Jinan 7
Napoli 7
Tianjin 7
Chandigarh 6
Fes 6
London 6
Manchester 6
New Delhi 6
Norwalk 6
Ortona 6
Redondo Beach 6
San Francisco 6
Uster 6
Atlanta 5
Buenos Aires 5
Caivano 5
Cava de' Tirreni 5
Domicella 5
Guangzhou 5
Haiphong 5
Mumbai 5
Nocera Superiore 5
Pozzuoli 5
San Diego 5
Toronto 5
Totale 13.003
Nome #
Predicting PROTAC-mediated ternary complex structures through in silico approaches 2.166
A Combinatorial Virtual Screening Approach Driving the Synthesis of 2,4-Thiazolidinedione-Based Molecules as New Dual mPGES-1/5-LO Inhibitors 1.095
Inhibition of Microsomal Prostaglandin E2 Synthase 1: focused design of new anti-inflammatory and anti-cancer drugs 907
Protein Preparation Automatic Protocol for High-Throughput Inverse Virtual Screening: Accelerating the Target Identification by Computational Methods 566
New TRPM8 blockers exert anticancer activity over castration-resistant prostate cancer models 549
Inverse Virtual Screening for the rapid re-evaluation of the presumed biological safe profile of natural products. The case of steviol from Stevia rebaudiana glycosides on farnesoid X receptor (FXR) 527
In Silico Design, Chemical Synthesis, Biophysical and in Vitro Evaluation for the Identification of 1-Ethyl-1H-Pyrazolo[3,4-b]Pyridine-Based BRD9 Binders 493
Target identification by structure-based computational approaches: Recent advances and perspectives 442
Phytochemical investigation of Cannabis sativa: Isolation and structure determination of spiroindans 412
Exploration of TRPM8 Binding Sites by β-Carboline-Based Antagonists and Their in Vitro Characterization and in Vivo Analgesic Activities 372
Identification of Novel Bromodomain-Containing Protein 4 (BRD4) Binders through 3D Pharmacophore-Based Repositioning Screening Campaign 366
Insights into the ligand binding to bromodomain‐containing protein 9 (BRD9): A guide to the selection of potential binders by computational methods 294
Giffonins J-P, Highly Hydroxylated Cyclized Diarylheptanoids from the Leaves of Corylus avellana Cultivar "Tonda di Giffoni" 270
PharmaCore: The Automatic Generation of 3D Structure-Based Pharmacophore Models from Protein/Ligand Complexes 266
9H-purine scaffold reveals induced-fit pocket plasticity of the BRD9 bromodomain 222
Investigation analysis of the phytochemical composition of Laurus nobilis L. leaves essential oil: a study of the antioxidant and anti-inflammatory properties using a combination of in vitro and in silico methods 217
Essential Oils of Laurus nobilis L.: From Chemical Analysis to In Silico Investigation of Anti-Inflammatory Activity by Soluble Epoxide Hydrolase (sEH) Inhibition 197
Identification of a dual acting SARS-CoV-2 proteases inhibitor through in silico design and step-by-step biological characterization 182
Structural Evidence ofN6-Isopentenyladenosine As a New Ligand of Farnesyl Pyrophosphate Synthase 176
Bissubvilides A and B, Cembrane-capnosane heterodimers from the soft coral sarcophyton subviride 166
Structural Insights for the Optimization of Dihydropyrimidin-2(1H)-one Based mPGES-1 Inhibitors 156
Exploration of the dihydropyrimidine scaffold for the development of new potential anti-inflammatory agents blocking prostaglandin E2 synthase-1 enzyme (mPGES-1) 154
Plakilactones from the marine sponge Plakinastrella mamillaris. Discovery of a new class of marine ligands of peroxisome proliferator-activated receptor γ 146
Biological Profile of Two Gentiana lutea L. Metabolites Using Computational Approaches and In Vitro Tests 144
Oxygenated polyketides from plakinastrella mamillaris as a new chemotype of PXR agonists 139
Chemical proteomics reveals HSP70 1A as a target for the anticancer diterpene oridonin in Jurkat cells 135
Identification of novel microsomal prostaglandin E2 synthase-1 (mPGES-1) lead inhibitors from Fragment Virtual Screening 132
Discovery and Synthesis of Namalide Reveals a New Anabaenopeptin Scaffold and Peptidase Inhibitor 125
Anti-inflammatory trends of new benzimidazole derivatives 121
Inhibition of Wnt/β-Catenin pathway and Histone acetyltransferase activity by Rimonabant: a therapeutic target for colon cancer 117
Targeting Microsomal Prostaglanding E2 Synthase 1 for the Development of new potential Anti-Inflammatory Drugs 110
Chemistry and Selective Tumor Cell Growth Inhibitory Activity of Polyketides from the South China Sea Sponge Plakortis sp 106
Hyalachelins A–C, Unusual Siderophores Isolated from the Terrestrial MyxobacteriumHyalangium minutum 105
Cyclic Diarylheptanoids from Corylus avellana Green Leafy Covers: Determination of Their Absolute Configurations and Evaluation of Their Antioxidant and Antimicrobial Activities 103
Modification in the side chain of solomonsterol A: discovery of cholestan disulfate as a potent pregnane-X-receptor agonist 102
Discovery and synthesis of the first selective BAG domain modulator of BAG3 as an attractive candidate for the development of a new class of chemotherapeutics 101
Structure-Based Design of Microsomal Prostaglandin E2 Synthase-1 (mPGES-1) Inhibitors using a Virtual Fragment Growing Optimization Scheme 99
The plant diterpene epoxysiderol targets Hsp70 in cancer cells, affecting its ATPase activity and reducing its translocation to plasma membrane 95
Identification of 2,4,5-trisubstituted-2,4-dihydro-3H-1,2,4-triazol-3-one-based small molecules as selective BRD9 binders 94
Dihydroaurones and Isoflavan Derivatives from the Roots of Glycyrrhiza asymmetrica 93
New Steroids with a Rearranged Skeleton as (h)P300 Inhibitors from the SpongeTheonella swinhoei 93
DFT/NMR Approach for the Configuration Assignment of Groups of Stereoisomers by the Combination and Comparison of Experimental and Predicted Sets of Data 93
Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19) 93
Pharmacological evaluation and docking studies of α,β-unsaturated carbonyl based synthetic compounds as inhibitors of secretory phospholipase A2, cyclooxygenases, lipoxygenase and proinflammatory cytokines 91
Corylus avellana: A Source of Diarylheptanoids With α-Glucosidase Inhibitory Activity Evaluated by in vitro and in silico Studies 91
2-Substituted 1,5-benzothiazepine-based HDAC inhibitors exert anticancer activities on human solid and acute myeloid leukemia cell lines 89
Inverse Virtual Screening of Antitumor Targets: Pilot Study on a Small Database of Natural Bioactive Compounds 88
Ring-Fused Cyclic Aminals from Tetrahydro-β-carboline-Based Dipeptide Compounds 88
Inverse Virtual Screening allows the discovery of the biological activity of natural compounds 87
Glucopyranosylbianthrones from the Algerian Asphodelus tenuifolius: Structural Insights and Biological Evaluation on Melanoma Cancer Cells 84
Tulongicin, an Antibacterial Tri-Indole Alkaloid from a Deep-Water Topsentia sp. Sponge 84
A Comprehensive In Vitro Characterization of a New Class of Indole-Based Compounds Developed as Selective Haspin Inhibitors 79
Identification of an indol-based multi-target kinase inhibitor through phenotype screening and target fishing using inverse virtual screening approach 79
Novel para‐phenylenediamine‐based derivatives as Receptor Tyrosine Kinase‐like Orphan Receptor 1 (ROR1) Inhibitors: An in vitro preliminary characterization 77
Discovery of noscapine derivatives as potential β-tubulin inhibitors 77
Svetamycins A-G, Unusual Piperazic Acid-Containing Peptides from Streptomyces sp 76
Chemoproteomics Reveals USP5 (Ubiquitin Carboxyl-Terminal Hydrolase 5) as Promising Target of the Marine Polyketide Gracilioether A 76
6-Methylquinazolin-4(3H)-one Based Compounds as BRD9 Epigenetic Reader Binders: A Rational Combination of in silico Studies and Chemical Synthesis 71
Reranking docking poses using molecular simulations and approximate free energy methods 69
Addressing the Target Identification and Accelerating the Repositioning of Anti-Inflammatory/Anti-Cancer Organic Compounds by Computational Approaches 69
Virtual screening of 3-(1H-1,2,3-triazol-1-yl)piperidine-2,6-dione-based compounds as new potential Cereblon modulators amenable for targeted protein degradation 66
Exploring the chemical space of functionalized [1,2,4]triazolo[4,3-a]quinoxaline-based compounds targeting the bromodomain of BRD9 66
Structural Refinement of 2,4-Thiazolidinedione Derivatives as New Anticancer Agents Able to Modulate the BAG3 Protein 65
Discovery of a Secalonic Acid Derivative from Aspergillus aculeatus, an Endophyte of Rosa damascena Mill., Triggers Apoptosis in MDA-MB-231 Triple Negative Breast Cancer Cells 63
Discovery of 3-hydroxy-3-pyrrolin-2-one-based mPGES-1 inhibitors using a multi-step virtual screening protocol 62
Identification of the first-in-class dual inhibitor targeting BAG3 and HSP70 proteins to disrupt multiple chaperone pathways 61
In Silico, In Vitro, and In Vivo Analysis of Tanshinone IIA and Cryptotanshinone from Salvia miltiorrhiza as Modulators of Cyclooxygenase-2/mPGES-1/Endothelial Prostaglandin EP3 Pathway 61
Unveiling the Potential Biological and Chemical Mechanism of Pergularia tomentosa Extracts by Liquid Chromatography‐Electrospray Ionisation‐High‐Resolution Tandem Mass Spectrometry, In‐Vitro and In‐Vivo Pharmacological Studies 61
Isolation, Synthesis And Structure Determination Of Cannabidiol Derivatives And Their Cytotoxic Activities 60
Giffonins, Antioxidant Diarylheptanoids from Corylus avellana, and Their Ability to Prevent Oxidative Changes in Human Plasma Proteins 60
Repositioning of Quinazolinedione-Based Compounds on Soluble Epoxide Hydrolase (sEH) through 3D Structure-Based Pharmacophore Model-Driven Investigation 59
Elucidating the Relative and Absolute Configuration of Organic Compounds by Quantum Mechanical Approaches 59
Introducing structure-based three-dimensional pharmacophore models for accelerating the discovery of selective BRD9 binders 59
Peptidomimetics as potent dual SARS-CoV-2 cathepsin-L and main protease inhibitors: In silico design, synthesis and pharmacological characterization 57
Immunomodulatory Biscembranoids and Assignment of Their Relative and Absolute Configurations: Data Set Modulation in the Density Functional Theory/Nuclear Magnetic Resonance Approach 55
Furazanopyrazine-based novel promising anticancer agents interfering with the eicosanoid biosynthesis pathways by dual mPGES-1 and sEH inhibition 52
Thiazolidin-4-one-based compounds interfere with the eicosanoid biosynthesis pathways by mPGES-1/sEH/5-LO multi-target inhibition 52
NMR Metabolomics and Chemometrics of Commercial Varieties of Phaseolus vulgaris L. Seeds from Italy and In Vitro Antioxidant and Antifungal Activity 50
Total synthesis of the potent anti-inflammatory natural product solomonamide A along with structural revision and biological activity evaluation 50
5-methyl-2-carboxamidepyrrole-based novel dual mPGES-1/sEH inhibitors as promising anticancer candidates 48
Phytochemical Analysis of the Methanolic Extract and Essential Oil from Leaves of Industrial Hemp Futura 75 Cultivar: Isolation of a New Cannabinoid Derivative and Biological Profile Using Computational Approaches 46
Fatty Acid Synthase as Interacting Anticancer Target of the Terpenoid Myrianthic Acid Disclosed by MS-Based Proteomics Approaches 40
Untargeted Diversity-Oriented Synthesis for the Discovery of New Antitumor Agents: An Integrated Approach of Inverse Virtual Screening, Bioinformatics, and Omics for Target Deconvolution 39
Chemical Profiling of Polar Lipids and the Polyphenolic Fraction of Commercial Italian Phaseolus Seeds by UHPLC-HRMS and Biological Evaluation 39
Identification of a New Promising BAG3 Modulator Featuring the Imidazopyridine Scaffold 37
Repositioning of Small Molecules through the Inverse Virtual Screening in silico Tool: Case of Benzothiazole-Based Inhibitors of Soluble Epoxide Hydrolase (sEH) 33
Scabiosa atropurpurea: A rich source of iridoids with α-glucosidase inhibitory activity evaluated by in vitro and in silico studies 28
Extensive Molecular Dynamics Simulations Disclosed the Stability of mPGES-1 Enzyme and the Structural Role of Glutathione (GSH) Cofactor 27
Identification and Development of BRD9 Chemical Probes 26
A Classic Photochemical Approach Inducing an Unexpected Rearrangement: Exploring the Photoreactivity of Pentacyclic Triterpenic Acids 25
Identification of 2-Aminoacyl-1,3,4-thiadiazoles as Prostaglandin E2 and Leukotriene Biosynthesis Inhibitors 24
Totale 15.446
Categoria #
all - tutte 37.559
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 37.559


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021282 0 0 0 0 27 14 54 10 76 9 40 52
2021/2022393 3 1 8 20 24 6 6 19 58 43 49 156
2022/2023740 58 77 19 115 76 142 12 72 95 5 43 26
2023/2024385 17 40 31 21 43 90 24 24 13 21 11 50
2024/20252.207 58 14 11 71 47 115 388 115 248 73 180 887
2025/20269.984 3.004 3.426 3.077 477 0 0 0 0 0 0 0 0
Totale 15.446