PUCA, Annibale Alessandro
 Distribuzione geografica
Continente #
AS - Asia 11.919
NA - Nord America 6.800
EU - Europa 4.268
SA - Sud America 715
AF - Africa 116
OC - Oceania 15
Continente sconosciuto - Info sul continente non disponibili 8
Totale 23.841
Nazione #
HK - Hong Kong 7.904
US - Stati Uniti d'America 6.658
FI - Finlandia 1.961
SG - Singapore 1.894
CN - Cina 775
VN - Vietnam 646
IT - Italia 632
BR - Brasile 538
RU - Federazione Russa 386
UA - Ucraina 384
DE - Germania 240
IE - Irlanda 170
FR - Francia 153
KR - Corea 147
TR - Turchia 129
IN - India 105
AR - Argentina 80
GB - Regno Unito 79
BD - Bangladesh 71
SE - Svezia 69
CA - Canada 63
MX - Messico 44
NL - Olanda 40
AT - Austria 33
ID - Indonesia 33
JP - Giappone 32
ZA - Sudafrica 31
IQ - Iraq 28
ES - Italia 27
PL - Polonia 27
PK - Pakistan 23
UZ - Uzbekistan 21
EC - Ecuador 19
VE - Venezuela 18
CO - Colombia 17
MA - Marocco 16
PY - Paraguay 16
SA - Arabia Saudita 15
MY - Malesia 14
CZ - Repubblica Ceca 13
EG - Egitto 12
KE - Kenya 11
AU - Australia 10
CL - Cile 10
JO - Giordania 10
UY - Uruguay 10
AZ - Azerbaigian 9
ET - Etiopia 9
LT - Lituania 8
TN - Tunisia 8
AE - Emirati Arabi Uniti 7
DK - Danimarca 7
EU - Europa 6
LB - Libano 6
PH - Filippine 6
BE - Belgio 5
DO - Repubblica Dominicana 5
DZ - Algeria 5
KZ - Kazakistan 5
NI - Nicaragua 5
OM - Oman 5
PE - Perù 5
BY - Bielorussia 4
CH - Svizzera 4
HN - Honduras 4
JM - Giamaica 4
LV - Lettonia 4
NG - Nigeria 4
NP - Nepal 4
PA - Panama 4
TH - Thailandia 4
AL - Albania 3
CR - Costa Rica 3
GR - Grecia 3
HU - Ungheria 3
IL - Israele 3
LA - Repubblica Popolare Democratica del Laos 3
PS - Palestinian Territory 3
SN - Senegal 3
TT - Trinidad e Tobago 3
AF - Afghanistan, Repubblica islamica di 2
AM - Armenia 2
BA - Bosnia-Erzegovina 2
BH - Bahrain 2
BW - Botswana 2
GA - Gabon 2
GN - Guinea 2
IR - Iran 2
KW - Kuwait 2
MD - Moldavia 2
MK - Macedonia 2
NZ - Nuova Zelanda 2
RO - Romania 2
SY - Repubblica araba siriana 2
TW - Taiwan 2
TZ - Tanzania 2
XK - ???statistics.table.value.countryCode.XK??? 2
BB - Barbados 1
BF - Burkina Faso 1
BG - Bulgaria 1
Totale 23.815
Città #
Hong Kong 7.895
Helsinki 1.866
Ann Arbor 990
Singapore 876
San Jose 662
Chandler 533
Princeton 505
Jacksonville 463
Ashburn 380
Dallas 374
Wilmington 309
Woodbridge 273
Dong Ket 253
Council Bluffs 177
Dublin 162
Ho Chi Minh City 152
Beijing 146
The Dalles 138
Lauterbourg 136
Nanjing 129
Andover 112
Naples 104
Izmir 101
Los Angeles 88
Moscow 84
Boardman 82
Hanoi 78
Houston 77
Munich 77
Salerno 74
New York 65
Pellezzano 60
São Paulo 56
Dearborn 45
Fairfield 41
Nuremberg 37
Santa Clara 33
Shenyang 33
Chennai 32
Orem 31
Tokyo 31
Milan 30
Norwalk 30
Hebei 29
Columbus 28
Changsha 27
Jiaxing 26
Haiphong 25
Montreal 25
Nanchang 25
Seattle 25
Tianjin 25
Brooklyn 24
Redwood City 24
Turku 24
Warsaw 24
London 21
Stockholm 21
Denver 20
Tashkent 20
Da Nang 19
Chicago 18
Washington 18
Fisciano 17
San Diego 17
Frankfurt am Main 16
Jinan 16
Amsterdam 15
Atlanta 15
Johannesburg 15
Mexico City 15
Rome 15
Falls Church 14
Manchester 14
Mestre 14
Phoenix 14
Rio de Janeiro 13
Sarno 13
Mercato San Severino 12
Boston 11
Brno 11
Campinas 11
Curitiba 11
Düsseldorf 11
San Francisco 11
Belo Horizonte 10
Nizhniy Novgorod 10
Quito 10
Salvador 10
Seoul 10
Vienna 10
Addis Ababa 9
Ankara 9
Dhaka 9
Gatchina 9
Montevideo 9
Mumbai 9
Nairobi 9
Toronto 9
Zhengzhou 9
Totale 18.730
Nome #
A bioavailability study on microbeads and nanoliposomes fabricated by dense carbon dioxide technologies using human-primary monocytes and flow cytometry assay 2.051
Diet and Longevity Phenotype 1.207
Circulating BPIFB4 Levels Associate With and Influence the Abundance of Reparative Monocytes and Macrophages in Long Living Individuals 583
The Longevity-Associated Variant of BPIFB4 Reduces Senescence in Glioma Cells and in Patients’ Lymphocytes Favoring Chemotherapy Efficacy 527
The longevity-associated BPIFB4 gene guarantees vascular homeostasis and immune protection through platelets 508
Serum BPIFB4 levels classify health status in long-living individuals 506
High TARC plasma levels confer protection to long living individuals by inducing M2 profile 503
Antioxidant effects of resveratrol in cardiovascular, cerebral and metabolic diseases. 475
A G613A missense in the Hutchinson's progeria lamin A/C gene causes a lone, autosomal dominant atrioventricular block 460
Klebsiella pneumoniae-OMVs activate death-signaling pathways in Human Bronchial Epithelial Host Cells (BEAS-2B) 423
Genetic signatures of exceptional longevity in humans. 365
Rac1 pharmacological inhibition rescues human endothelial dysfunction 360
Centenarians as a model to discover genetic and epigenetic signatures of healthy ageing 360
LAV-BPIFB4 isoform modulates eNOS signaling through Ca2+/PKC-alpha dependent mechanism 358
LAV-BPIFB4 associates with reduced frailty in humans and its transfer prevents frailty progression in old mice 344
SLITRK2, an X-linked modifier of the age at onset in C9orf72 frontotemporal lobar degeneration 332
Transfer of the longevity-associated variant of BPIFB4 gene rejuvenates immune system and vasculature by a reduction of CD38+ macrophages and NAD+ decline 293
A rare genetic variant of BPIFB4 predisposes to high blood pressure via impairment of nitric oxide signaling 266
Gender Differences Associated with the Prognostic Value of BPIFB4 in COVID-19 Patients: A Single-Center Preliminary Study 222
Longevity-associated BPIFB4 gene counteracts the inflammatory signaling 218
Single systemic transfer of a human gene associated with exceptional longevity halts the progression of atherosclerosis and inflammation in ApoE knockout mice through a CXCR4-mediated mechanism 213
Polymorphisms of the antiapoptotic protein bag3 may play a role in the pathogenesis of tako-tsubo cardiomyopathy 191
Transfer of a human gene variant associated with exceptional longevity improves cardiac function in obese type 2 diabetic mice through induction of the SDF-1/CXCR4 signalling pathway 191
Sortilin evokes endothelial dysfunction and arterial hypertension through the dysregulation of sphingolipid metabolism and oxidative stress 189
Risk factors and acute ischemic stroke subtypes 181
The anti-ageing molecule sirt1 mediates beneficial effects of cardiac rehabilitation 181
Bisphenol A induces DNA damage in cells exerting immune surveillance functions at peripheral and central level 168
Innate immunity and cellular senescence: The good and the bad in the developmental and aged brain 166
The inflammatory protein Pentraxin 3 in cardiovascular disease 157
Brain diseases and tumorigenesis: The good and bad cops of pentraxin3 149
Association Study on Long-Living Individuals from Southern Italy Identifies rs10491334 in the CAMKIV Gene That Regulates Survival Proteins. 149
Ankyrin-B syndrome: enhanced cardiac function balanced by risk of cardiac death and premature senescence. 148
Endothelial nitric oxide synthase, vascular integrity and human exceptional longevity 147
The expression of the BPIFB4 and CXCR4 associates with sustained health in long-living individuals from Cilento-Italy 145
BPIFB4 Circulating Levels and Its Prognostic Relevance in COVID-19 145
Human platelets and megakaryocytes express the BPIFB4 protein and their stimulation with the recombinant Longevity-associated variant LAV-BPIFB4 displays anti-aggregating activity 144
Assessment of the 9p21.3 locus in severity of coronary artery disease in the presence and absence of type 2 diabetes. 144
A genome-wide screening and SNPs-to-genes approach to identify novel genetic risk factors associated with frontotemporal dementia 143
GRN deletion in familial frontotemporal dementia showing association with clinical variability in 3 familial cases 137
A novel p53 mutant in human breast cancer revealed by multiple SSCP analysis. 135
CaMK4 Gene Deletion Induces Hypertension 135
Longevity-Associated Variant of BPIFB4 Mitigates Monocyte-Mediated Acquired Immune Response 135
Autosomal recessive limb-girdle muscular dystrophy, LGMD2F, is caused by a mutation in the delta-sarcoglycan gene. 134
Association of rs2200733 at 4q25 with atrial flutter/fibrillation diseases in an Italian population. 133
Morus alba extract modulates blood pressure homeostasis through eNOS signaling 132
Identification of a novel sarcoglycan gene at 5q33 encoding a sarcolemmal 35 kDa glycoprotein. 131
Resveratrol Improves Vascular Function in Patients With Hypertension and Dyslipidemia by Modulating NO Metabolism. 130
Targeting the ASMase/S1P pathway protects from sortilin-evoked vascular damage in hypertension 129
Exome sequencing of a family with lone, autosomal dominant atrial flutter identifies a rare variation in ABCB4 significantly enriched in cases 128
A DNA methylation fingerprint of 1628 human samples. 125
A caccia dei Geni della Longevita' 124
A model of evolutionary selection: The cardiovascular protective function of the longevity associated variant of BPIFB4 124
APOE Alleles and Extreme Human Longevity 123
Corrigendum to “A bioavailability study on microbeads and nanoliposomes fabricated by dense carbon dioxide technologies using human-primary monocytes and flow cytometry assay” (International Journal of Pharmaceutics (2019) 570, (S0378517319307318), (10.1016/j.ijpharm.2019.118686)) 123
SIRT1 pharmacological activation rescues vascular dysfunction and prevents thrombosis in MTHFR deficiency 122
Association of the FOXO3A locus with extreme longevity in a southern Italian centenarian study. 122
Targeting Nitric Oxide with Natural Derived Compounds as a Therapeutic Strategy in Vascular Diseases 122
Genetic Analysis Reveals a Longevity-Associated Protein Modulating Endothelial Function and Angiogenesis 121
Multi-criteria decision making approaches for quality control of genome-wide association studies. 120
Pathogenic Huntingtin Repeat Expansions in Patients with Frontotemporal Dementia and Amyotrophic Lateral Sclerosis 120
Limitations and risks of meta-analyses of longevity studies 117
A genome-wide scan for linkage to human exceptional longevity identifies a locus on chromosome 4. 117
Optimizing mRNA delivery: A microfluidic exploration of DOTMA vs. DOTAP lipid nanoparticles for GFP expression on human PBMCs and THP-1 cell line 115
Association of immunoglobulin GM allotypes with longevity in long-living individuals from Southern Italy 114
RNA Editing Genes Associated with Extreme Old Age in Humans and with Lifespan in C. elegans 112
Stem cell and macrophage roles in skeletal muscle regenerative medicine 112
Blood biomarkers role in acute ischemic stroke patients: higher is worse or better? 111
Frontotemporal dementia and its subtypes: a genome-wide association study. 110
Old, Nonagenarians, and Centenarians in Cilento, Italy and the Association of Lifespan with the Level of Some Physicochemical Elements in Tap Drinking Water 109
Vascular ageing: The role of oxidative stress. 108
Butyrate as bioactive human milk protective component against food allergy 108
Pentraxin 3 induces vascular endothelial dysfunction through a P-selectin/matrix metalloproteinase-1 pathway 107
Lipid metabolism and diet: possible mechanisms of slow aging. 107
The genetics of aging. 107
BPIFB4 missense variants associate with exceptional longevity in independent populations and influence cell signaling 106
New Nutraceutical Combination Reduces Blood Pressure and Improves Exercise Capacity in Hypertensive Patients Via a Nitric Oxide-Dependent Mechanism 105
A novel human serine-threonine phosphatase related to the Drosophila retinal degeneration C (rdgC) gene is selectively expressed in sensory neurons of neural crest origin. 104
Gamma1- and gamma2-syntrophins, two novel dystrophin-binding proteins localized in neuronal cells. 103
The Role of BPIFB4 in Immune System and Cardiovascular Disease: The Lesson from Centenarians 103
The longevity-associated variant of BPIFB4 improves a CXCR4-mediated striatum–microglia crosstalk preventing disease progression in a mouse model of Huntington’s disease 102
Genetic Loci Indicative of Propensity for Longevity and methods for Identifying Propensity for Age-Related Disease 101
Clinical Status, Nutritional Behavior, and Lifestyle, and Determinants of Community Well-Being of Patients from the Perspective of Physicians: A Cross-Sectional Study of Young Older Adults, Nonagenarians, and Centenarians in Salerno and Province, Italy 100
SARS-CoV-2 Lysate Stimulation Impairs the Release of Platelet-like Particles and Megakaryopoiesis in the MEG-01 Cell Line 100
Four Genome-Wide Association Studies Identify New Extreme Longevity Variants 100
A donor splice site mutation in CISD2 generates multiple truncated, non-functional isoforms in Wolfram syndrome type 2 patients 99
Interaction between Diet and Genes on LongevityNutritional and Metabolic Bases of Cardiovascular Disease 98
Genetic signature of exceptional longevity 98
The Genetics Applied to Centenarians 98
The application of genetics approaches to the study of exceptional longevity in humans: potential and limitations 97
Effects of Human LAV-BPIFB4 Gene Therapy on the Epigenetic Clock and Health of Aged Mice 95
Immune-related genetic enrichment in frontotemporal dementia: An analysis of genome-wide association studies 95
Meta-analysis of genetic variants associated with human exceptional longevity. 94
S -nitrosylation drives cell senescence and aging in mammals by controlling mitochondrial dynamics and mitophagy 92
Identification of evolutionarily conserved gene networks mediating neurodegenerative dementia 91
Immunomodulatory activity of Humulus lupulus bitter acids fraction: Enhancement of natural killer cells function by NKp44 activating receptor stimulation 90
Candidate gene study of FOXO1, FOXO4, and FOXO6 reveals no association with human longevity in Germans. 89
Role of cytosolic calcium-dependent phospholipase A2 in Alzheimer's disease pathogenesis. 89
Correlations between progression of coronary artery disease and circulating endothelial progenitor cells. 87
New insights for BPIFB4 in cardiovascular therapy 86
null 85
Totale 20.178
Categoria #
all - tutte 66.612
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 66.612


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021360 0 0 0 0 0 0 0 0 0 11 78 271
2021/2022862 5 3 1 18 28 15 7 52 122 102 124 385
2022/20231.347 143 84 93 143 188 282 8 124 190 6 57 29
2023/2024622 46 97 49 26 60 63 41 33 14 36 17 140
2024/20252.028 65 33 57 90 67 243 284 222 369 105 225 268
2025/202615.308 1.396 4.236 3.209 575 932 402 1.309 271 2.316 662 0 0
Totale 24.243