PUCA, Annibale Alessandro
 Distribuzione geografica
Continente #
AS - Asia 10.693
NA - Nord America 5.413
EU - Europa 2.122
SA - Sud America 564
AF - Africa 51
OC - Oceania 15
Continente sconosciuto - Info sul continente non disponibili 8
Totale 18.866
Nazione #
HK - Hong Kong 7.842
US - Stati Uniti d'America 5.312
SG - Singapore 1.328
CN - Cina 684
IT - Italia 596
BR - Brasile 465
VN - Vietnam 403
RU - Federazione Russa 381
UA - Ucraina 375
DE - Germania 217
IE - Irlanda 167
KR - Corea 138
TR - Turchia 109
FI - Finlandia 107
SE - Svezia 67
IN - India 55
CA - Canada 54
GB - Regno Unito 53
AR - Argentina 51
AT - Austria 30
NL - Olanda 30
BD - Bangladesh 29
MX - Messico 27
PL - Polonia 24
ID - Indonesia 23
ES - Italia 21
JP - Giappone 17
CZ - Repubblica Ceca 13
AU - Australia 10
UZ - Uzbekistan 10
VE - Venezuela 10
ZA - Sudafrica 10
EC - Ecuador 9
MA - Marocco 9
IQ - Iraq 8
PY - Paraguay 8
CO - Colombia 7
FR - Francia 7
KE - Kenya 7
LT - Lituania 7
MY - Malesia 7
PK - Pakistan 7
EG - Egitto 6
EU - Europa 6
BE - Belgio 5
PE - Perù 5
UY - Uruguay 5
AE - Emirati Arabi Uniti 4
CH - Svizzera 4
NI - Nicaragua 4
TN - Tunisia 4
CL - Cile 3
DO - Repubblica Dominicana 3
LA - Repubblica Popolare Democratica del Laos 3
SA - Arabia Saudita 3
TT - Trinidad e Tobago 3
AF - Afghanistan, Repubblica islamica di 2
BW - Botswana 2
BY - Bielorussia 2
DK - Danimarca 2
DZ - Algeria 2
GR - Grecia 2
HN - Honduras 2
HU - Ungheria 2
IL - Israele 2
IR - Iran 2
KZ - Kazakistan 2
LB - Libano 2
NG - Nigeria 2
NP - Nepal 2
NZ - Nuova Zelanda 2
OM - Oman 2
PA - Panama 2
RO - Romania 2
XK - ???statistics.table.value.countryCode.XK??? 2
AL - Albania 1
AM - Armenia 1
AZ - Azerbaigian 1
BA - Bosnia-Erzegovina 1
BB - Barbados 1
BZ - Belize 1
CU - Cuba 1
CV - Capo Verde 1
DM - Dominica 1
EE - Estonia 1
GA - Gabon 1
GE - Georgia 1
GN - Guinea 1
IS - Islanda 1
KH - Cambogia 1
KW - Kuwait 1
LC - Santa Lucia 1
LI - Liechtenstein 1
LV - Lettonia 1
MD - Moldavia 1
MG - Madagascar 1
MK - Macedonia 1
ML - Mali 1
MU - Mauritius 1
NR - Nauru 1
Totale 18.855
Città #
Hong Kong 7.836
Ann Arbor 990
Chandler 533
Princeton 505
Singapore 484
Jacksonville 463
Dallas 373
Wilmington 309
Woodbridge 273
Dong Ket 253
Ashburn 206
Dublin 159
Beijing 131
Nanjing 127
Andover 112
Naples 103
Izmir 101
Moscow 84
Boardman 81
Munich 77
Los Angeles 74
Houston 73
Salerno 72
Ho Chi Minh City 70
Pellezzano 60
New York 55
São Paulo 49
Dearborn 45
Fairfield 41
Shenyang 33
The Dalles 32
Nuremberg 31
Norwalk 30
Hebei 29
Changsha 27
Hanoi 27
Milan 27
Columbus 26
Jiaxing 26
Nanchang 25
Seattle 25
Tianjin 25
Redwood City 24
Turku 24
Warsaw 22
Chennai 21
Montreal 21
Brooklyn 19
Stockholm 19
San Diego 17
Fisciano 16
Jinan 16
Tokyo 16
Santa Clara 15
Washington 15
Falls Church 14
Mestre 14
Rome 14
Chicago 13
Council Bluffs 13
Sarno 13
Denver 12
Haiphong 12
Helsinki 12
Mercato San Severino 12
Orem 12
Brno 11
Curitiba 11
Düsseldorf 11
London 11
Phoenix 11
Rio de Janeiro 11
Belo Horizonte 10
Manchester 10
Mexico City 10
Nizhniy Novgorod 10
Seoul 10
Tashkent 10
Atlanta 9
Boston 9
Gatchina 9
San Francisco 9
Vienna 9
Zhengzhou 9
Ottawa 8
Salvador 8
Amsterdam 7
Ankara 7
Campinas 7
Guangzhou 7
Mumbai 7
Napoli 7
St Petersburg 7
Toronto 7
Brasília 6
Cambridge 6
Hangzhou 6
Jakarta 6
Johannesburg 6
Kunming 6
Totale 14.776
Nome #
Diet and Longevity Phenotype 1.191
Circulating BPIFB4 Levels Associate With and Influence the Abundance of Reparative Monocytes and Macrophages in Long Living Individuals 559
The Longevity-Associated Variant of BPIFB4 Reduces Senescence in Glioma Cells and in Patients’ Lymphocytes Favoring Chemotherapy Efficacy 512
Serum BPIFB4 levels classify health status in long-living individuals 485
The longevity-associated BPIFB4 gene guarantees vascular homeostasis and immune protection through platelets 480
High TARC plasma levels confer protection to long living individuals by inducing M2 profile 475
Antioxidant effects of resveratrol in cardiovascular, cerebral and metabolic diseases. 452
A G613A missense in the Hutchinson's progeria lamin A/C gene causes a lone, autosomal dominant atrioventricular block 439
Klebsiella pneumoniae-OMVs activate death-signaling pathways in Human Bronchial Epithelial Host Cells (BEAS-2B) 400
Centenarians as a model to discover genetic and epigenetic signatures of healthy ageing 346
Genetic signatures of exceptional longevity in humans. 345
Rac1 pharmacological inhibition rescues human endothelial dysfunction 339
LAV-BPIFB4 isoform modulates eNOS signaling through Ca2+/PKC-alpha dependent mechanism 337
LAV-BPIFB4 associates with reduced frailty in humans and its transfer prevents frailty progression in old mice 320
SLITRK2, an X-linked modifier of the age at onset in C9orf72 frontotemporal lobar degeneration 311
Transfer of the longevity-associated variant of BPIFB4 gene rejuvenates immune system and vasculature by a reduction of CD38+ macrophages and NAD+ decline 268
A rare genetic variant of BPIFB4 predisposes to high blood pressure via impairment of nitric oxide signaling 244
Gender Differences Associated with the Prognostic Value of BPIFB4 in COVID-19 Patients: A Single-Center Preliminary Study 200
Longevity-associated BPIFB4 gene counteracts the inflammatory signaling 198
Single systemic transfer of a human gene associated with exceptional longevity halts the progression of atherosclerosis and inflammation in ApoE knockout mice through a CXCR4-mediated mechanism 197
A bioavailability study on microbeads and nanoliposomes fabricated by dense carbon dioxide technologies using human-primary monocytes and flow cytometry assay 173
Transfer of a human gene variant associated with exceptional longevity improves cardiac function in obese type 2 diabetic mice through induction of the SDF-1/CXCR4 signalling pathway 171
Sortilin evokes endothelial dysfunction and arterial hypertension through the dysregulation of sphingolipid metabolism and oxidative stress 168
Polymorphisms of the antiapoptotic protein bag3 may play a role in the pathogenesis of tako-tsubo cardiomyopathy 166
Risk factors and acute ischemic stroke subtypes 161
The anti-ageing molecule sirt1 mediates beneficial effects of cardiac rehabilitation 159
Innate immunity and cellular senescence: The good and the bad in the developmental and aged brain 148
The inflammatory protein Pentraxin 3 in cardiovascular disease 143
Bisphenol A induces DNA damage in cells exerting immune surveillance functions at peripheral and central level 136
Association Study on Long-Living Individuals from Southern Italy Identifies rs10491334 in the CAMKIV Gene That Regulates Survival Proteins. 133
Brain diseases and tumorigenesis: The good and bad cops of pentraxin3 130
The expression of the BPIFB4 and CXCR4 associates with sustained health in long-living individuals from Cilento-Italy 126
Human platelets and megakaryocytes express the BPIFB4 protein and their stimulation with the recombinant Longevity-associated variant LAV-BPIFB4 displays anti-aggregating activity 124
Assessment of the 9p21.3 locus in severity of coronary artery disease in the presence and absence of type 2 diabetes. 122
A genome-wide screening and SNPs-to-genes approach to identify novel genetic risk factors associated with frontotemporal dementia 122
Ankyrin-B syndrome: enhanced cardiac function balanced by risk of cardiac death and premature senescence. 122
GRN deletion in familial frontotemporal dementia showing association with clinical variability in 3 familial cases 121
CaMK4 Gene Deletion Induces Hypertension 116
Identification of a novel sarcoglycan gene at 5q33 encoding a sarcolemmal 35 kDa glycoprotein. 115
Morus alba extract modulates blood pressure homeostasis through eNOS signaling 115
Endothelial nitric oxide synthase, vascular integrity and human exceptional longevity 114
Autosomal recessive limb-girdle muscular dystrophy, LGMD2F, is caused by a mutation in the delta-sarcoglycan gene. 112
Resveratrol Improves Vascular Function in Patients With Hypertension and Dyslipidemia by Modulating NO Metabolism. 109
Targeting Nitric Oxide with Natural Derived Compounds as a Therapeutic Strategy in Vascular Diseases 109
Targeting the ASMase/S1P pathway protects from sortilin-evoked vascular damage in hypertension 109
Association of rs2200733 at 4q25 with atrial flutter/fibrillation diseases in an Italian population. 108
A novel p53 mutant in human breast cancer revealed by multiple SSCP analysis. 108
Exome sequencing of a family with lone, autosomal dominant atrial flutter identifies a rare variation in ABCB4 significantly enriched in cases 108
A model of evolutionary selection: The cardiovascular protective function of the longevity associated variant of BPIFB4 107
BPIFB4 Circulating Levels and Its Prognostic Relevance in COVID-19 107
A caccia dei Geni della Longevita' 106
Corrigendum to “A bioavailability study on microbeads and nanoliposomes fabricated by dense carbon dioxide technologies using human-primary monocytes and flow cytometry assay” (International Journal of Pharmaceutics (2019) 570, (S0378517319307318), (10.1016/j.ijpharm.2019.118686)) 106
Pathogenic Huntingtin Repeat Expansions in Patients with Frontotemporal Dementia and Amyotrophic Lateral Sclerosis 104
A DNA methylation fingerprint of 1628 human samples. 103
Limitations and risks of meta-analyses of longevity studies 102
Longevity-Associated Variant of BPIFB4 Mitigates Monocyte-Mediated Acquired Immune Response 101
Genetic Analysis Reveals a Longevity-Associated Protein Modulating Endothelial Function and Angiogenesis 100
Association of the FOXO3A locus with extreme longevity in a southern Italian centenarian study. 97
RNA Editing Genes Associated with Extreme Old Age in Humans and with Lifespan in C. elegans 97
Multi-criteria decision making approaches for quality control of genome-wide association studies. 95
A genome-wide scan for linkage to human exceptional longevity identifies a locus on chromosome 4. 95
SIRT1 pharmacological activation rescues vascular dysfunction and prevents thrombosis in MTHFR deficiency 93
Pentraxin 3 induces vascular endothelial dysfunction through a P-selectin/matrix metalloproteinase-1 pathway 93
Association of immunoglobulin GM allotypes with longevity in long-living individuals from Southern Italy 92
The genetics of aging. 90
Lipid metabolism and diet: possible mechanisms of slow aging. 89
Vascular ageing: The role of oxidative stress. 89
APOE Alleles and Extreme Human Longevity 89
Stem cell and macrophage roles in skeletal muscle regenerative medicine 89
BPIFB4 missense variants associate with exceptional longevity in independent populations and influence cell signaling 88
A novel human serine-threonine phosphatase related to the Drosophila retinal degeneration C (rdgC) gene is selectively expressed in sensory neurons of neural crest origin. 86
Blood biomarkers role in acute ischemic stroke patients: higher is worse or better? 85
Frontotemporal dementia and its subtypes: a genome-wide association study. 85
null 85
Interaction between Diet and Genes on LongevityNutritional and Metabolic Bases of Cardiovascular Disease 84
The Genetics Applied to Centenarians 84
Butyrate as bioactive human milk protective component against food allergy 84
Genetic Loci Indicative of Propensity for Longevity and methods for Identifying Propensity for Age-Related Disease 83
Four Genome-Wide Association Studies Identify New Extreme Longevity Variants 82
Genetic signature of exceptional longevity 81
The Role of BPIFB4 in Immune System and Cardiovascular Disease: The Lesson from Centenarians 81
Old, Nonagenarians, and Centenarians in Cilento, Italy and the Association of Lifespan with the Level of Some Physicochemical Elements in Tap Drinking Water 80
Clinical Status, Nutritional Behavior, and Lifestyle, and Determinants of Community Well-Being of Patients from the Perspective of Physicians: A Cross-Sectional Study of Young Older Adults, Nonagenarians, and Centenarians in Salerno and Province, Italy 79
Meta-analysis of genetic variants associated with human exceptional longevity. 79
New Nutraceutical Combination Reduces Blood Pressure and Improves Exercise Capacity in Hypertensive Patients Via a Nitric Oxide-Dependent Mechanism 79
Optimizing mRNA delivery: A microfluidic exploration of DOTMA vs. DOTAP lipid nanoparticles for GFP expression on human PBMCs and THP-1 cell line 78
Effects of Human LAV-BPIFB4 Gene Therapy on the Epigenetic Clock and Health of Aged Mice 77
A donor splice site mutation in CISD2 generates multiple truncated, non-functional isoforms in Wolfram syndrome type 2 patients 76
The longevity-associated variant of BPIFB4 improves a CXCR4-mediated striatum–microglia crosstalk preventing disease progression in a mouse model of Huntington’s disease 76
SARS-CoV-2 Lysate Stimulation Impairs the Release of Platelet-like Particles and Megakaryopoiesis in the MEG-01 Cell Line 75
Immune-related genetic enrichment in frontotemporal dementia: An analysis of genome-wide association studies 73
Identification of evolutionarily conserved gene networks mediating neurodegenerative dementia 72
Role of cytosolic calcium-dependent phospholipase A2 in Alzheimer's disease pathogenesis. 71
Candidate gene study of FOXO1, FOXO4, and FOXO6 reveals no association with human longevity in Germans. 70
The genetics of exceptional human longevity. 68
Correlations between progression of coronary artery disease and circulating endothelial progenitor cells. 68
The application of genetics approaches to the study of exceptional longevity in humans: potential and limitations 68
Identification of a DNA binding protein cooperating with estrogen receptor as RIZ (retinoblastoma interacting zinc finger protein). 68
Lack of sodium channel mutation in an Italian family with paramyotonia congenita. 67
Unexpectedly low mutation rates in beta-myosin heavy chain and cardiac myosin binding protein genes in Italian patients with hypertrophic cardiomyopathy. 66
Totale 16.188
Categoria #
all - tutte 59.538
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 59.538


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021729 0 0 0 0 88 105 90 4 82 11 78 271
2021/2022862 5 3 1 18 28 15 7 52 122 102 124 385
2022/20231.347 143 84 93 143 188 282 8 124 190 6 57 29
2023/2024622 46 97 49 26 60 63 41 33 14 36 17 140
2024/20252.028 65 33 57 90 67 243 284 222 369 105 225 268
2025/202610.333 1.396 4.236 3.209 575 917 0 0 0 0 0 0 0
Totale 19.268