PUCA, Annibale Alessandro
 Distribuzione geografica
Continente #
AS - Asia 12.086
NA - Nord America 7.444
EU - Europa 5.084
SA - Sud America 737
Continente sconosciuto - Info sul continente non disponibili 417
AF - Africa 117
OC - Oceania 15
Totale 25.900
Nazione #
HK - Hong Kong 7.943
US - Stati Uniti d'America 7.244
FI - Finlandia 1.961
SG - Singapore 1.930
IT - Italia 1.424
CN - Cina 833
VN - Vietnam 647
BR - Brasile 553
RU - Federazione Russa 386
UA - Ucraina 384
DE - Germania 240
IE - Irlanda 170
FR - Francia 157
KR - Corea 147
TR - Turchia 129
IN - India 105
BD - Bangladesh 104
CA - Canada 90
GB - Regno Unito 81
AR - Argentina 80
SE - Svezia 69
MX - Messico 49
NL - Olanda 41
ES - Italia 34
AT - Austria 33
ID - Indonesia 33
JP - Giappone 32
ZA - Sudafrica 31
IQ - Iraq 28
PL - Polonia 28
PK - Pakistan 23
UZ - Uzbekistan 21
CO - Colombia 20
EC - Ecuador 20
VE - Venezuela 18
MA - Marocco 16
PY - Paraguay 16
SA - Arabia Saudita 15
MY - Malesia 14
CZ - Repubblica Ceca 13
EG - Egitto 12
CL - Cile 11
JM - Giamaica 11
KE - Kenya 11
AU - Australia 10
JO - Giordania 10
UY - Uruguay 10
AZ - Azerbaigian 9
CH - Svizzera 9
ET - Etiopia 9
HN - Honduras 8
LT - Lituania 8
TN - Tunisia 8
TT - Trinidad e Tobago 8
AE - Emirati Arabi Uniti 7
DK - Danimarca 7
PE - Perù 7
CR - Costa Rica 6
EU - Europa 6
LB - Libano 6
NI - Nicaragua 6
PH - Filippine 6
BE - Belgio 5
BY - Bielorussia 5
DO - Repubblica Dominicana 5
DZ - Algeria 5
KZ - Kazakistan 5
LV - Lettonia 5
OM - Oman 5
GR - Grecia 4
NG - Nigeria 4
NP - Nepal 4
PA - Panama 4
TH - Thailandia 4
AL - Albania 3
BB - Barbados 3
HU - Ungheria 3
IL - Israele 3
LA - Repubblica Popolare Democratica del Laos 3
PS - Palestinian Territory 3
SN - Senegal 3
AF - Afghanistan, Repubblica islamica di 2
AM - Armenia 2
BA - Bosnia-Erzegovina 2
BG - Bulgaria 2
BH - Bahrain 2
BW - Botswana 2
GA - Gabon 2
GN - Guinea 2
IR - Iran 2
KW - Kuwait 2
MD - Moldavia 2
MK - Macedonia 2
NZ - Nuova Zelanda 2
RO - Romania 2
SV - El Salvador 2
SY - Repubblica araba siriana 2
TW - Taiwan 2
TZ - Tanzania 2
XK - ???statistics.table.value.countryCode.XK??? 2
Totale 25.461
Città #
Hong Kong 7.932
Helsinki 1.866
Ann Arbor 990
Singapore 897
San Jose 698
Chandler 533
Milan 516
Princeton 506
Jacksonville 465
Ashburn 421
Dallas 384
Wilmington 310
Woodbridge 273
Dong Ket 253
Council Bluffs 222
Beijing 191
Dublin 162
Ho Chi Minh City 152
Rome 139
The Dalles 139
Lauterbourg 136
Nanjing 129
Naples 118
Andover 112
Izmir 101
Los Angeles 98
Houston 84
Moscow 84
Boardman 82
Santa Clara 82
Hanoi 79
Munich 77
Salerno 76
New York 73
São Paulo 64
Pellezzano 60
Memphis 53
Figino 46
Dearborn 45
Fairfield 42
Nuremberg 37
Shenyang 33
Chennai 32
Orem 31
Tokyo 31
Brooklyn 30
Montreal 30
Norwalk 30
Columbus 29
Hebei 29
Changsha 27
Seattle 27
Jiaxing 26
Haiphong 25
Nanchang 25
Tianjin 25
Chicago 24
Denver 24
London 24
Redwood City 24
Turku 24
Warsaw 24
Stockholm 21
San Diego 20
Tashkent 20
Washington 20
Da Nang 19
Mexico City 18
Phoenix 18
Turin 18
Fisciano 17
Atlanta 16
Frankfurt am Main 16
Jinan 16
Toronto 16
Amsterdam 15
Johannesburg 15
Falls Church 14
Manchester 14
Mestre 14
San Francisco 14
Rio de Janeiro 13
Sarno 13
Bari 12
Boston 12
Mercato San Severino 12
Brno 11
Campinas 11
Curitiba 11
Düsseldorf 11
Belo Horizonte 10
Buffalo 10
Nizhniy Novgorod 10
Ottawa 10
Quito 10
Salvador 10
Seoul 10
Vienna 10
Addis Ababa 9
Alexandria 9
Totale 19.826
Nome #
A bioavailability study on microbeads and nanoliposomes fabricated by dense carbon dioxide technologies using human-primary monocytes and flow cytometry assay 2.058
Diet and Longevity Phenotype 1.213
Circulating BPIFB4 Levels Associate With and Influence the Abundance of Reparative Monocytes and Macrophages in Long Living Individuals 596
The Longevity-Associated Variant of BPIFB4 Reduces Senescence in Glioma Cells and in Patients’ Lymphocytes Favoring Chemotherapy Efficacy 539
The longevity-associated BPIFB4 gene guarantees vascular homeostasis and immune protection through platelets 528
Serum BPIFB4 levels classify health status in long-living individuals 516
High TARC plasma levels confer protection to long living individuals by inducing M2 profile 515
Antioxidant effects of resveratrol in cardiovascular, cerebral and metabolic diseases. 486
A G613A missense in the Hutchinson's progeria lamin A/C gene causes a lone, autosomal dominant atrioventricular block 471
Klebsiella pneumoniae-OMVs activate death-signaling pathways in Human Bronchial Epithelial Host Cells (BEAS-2B) 433
Genetic signatures of exceptional longevity in humans. 375
Rac1 pharmacological inhibition rescues human endothelial dysfunction 372
LAV-BPIFB4 isoform modulates eNOS signaling through Ca2+/PKC-alpha dependent mechanism 364
Centenarians as a model to discover genetic and epigenetic signatures of healthy ageing 363
LAV-BPIFB4 associates with reduced frailty in humans and its transfer prevents frailty progression in old mice 348
SLITRK2, an X-linked modifier of the age at onset in C9orf72 frontotemporal lobar degeneration 335
Transfer of the longevity-associated variant of BPIFB4 gene rejuvenates immune system and vasculature by a reduction of CD38+ macrophages and NAD+ decline 311
A rare genetic variant of BPIFB4 predisposes to high blood pressure via impairment of nitric oxide signaling 276
Gender Differences Associated with the Prognostic Value of BPIFB4 in COVID-19 Patients: A Single-Center Preliminary Study 235
Longevity-associated BPIFB4 gene counteracts the inflammatory signaling 229
Single systemic transfer of a human gene associated with exceptional longevity halts the progression of atherosclerosis and inflammation in ApoE knockout mice through a CXCR4-mediated mechanism 222
Sortilin evokes endothelial dysfunction and arterial hypertension through the dysregulation of sphingolipid metabolism and oxidative stress 200
Polymorphisms of the antiapoptotic protein bag3 may play a role in the pathogenesis of tako-tsubo cardiomyopathy 199
Transfer of a human gene variant associated with exceptional longevity improves cardiac function in obese type 2 diabetic mice through induction of the SDF-1/CXCR4 signalling pathway 198
Risk factors and acute ischemic stroke subtypes 192
Optimizing mRNA delivery: A microfluidic exploration of DOTMA vs. DOTAP lipid nanoparticles for GFP expression on human PBMCs and THP-1 cell line 189
The anti-ageing molecule sirt1 mediates beneficial effects of cardiac rehabilitation 188
Bisphenol A induces DNA damage in cells exerting immune surveillance functions at peripheral and central level 187
Innate immunity and cellular senescence: The good and the bad in the developmental and aged brain 179
The inflammatory protein Pentraxin 3 in cardiovascular disease 167
Brain diseases and tumorigenesis: The good and bad cops of pentraxin3 159
A genome-wide screening and SNPs-to-genes approach to identify novel genetic risk factors associated with frontotemporal dementia 158
BPIFB4 Circulating Levels and Its Prognostic Relevance in COVID-19 158
Association Study on Long-Living Individuals from Southern Italy Identifies rs10491334 in the CAMKIV Gene That Regulates Survival Proteins. 157
Human platelets and megakaryocytes express the BPIFB4 protein and their stimulation with the recombinant Longevity-associated variant LAV-BPIFB4 displays anti-aggregating activity 155
Assessment of the 9p21.3 locus in severity of coronary artery disease in the presence and absence of type 2 diabetes. 155
Ankyrin-B syndrome: enhanced cardiac function balanced by risk of cardiac death and premature senescence. 152
Endothelial nitric oxide synthase, vascular integrity and human exceptional longevity 151
The expression of the BPIFB4 and CXCR4 associates with sustained health in long-living individuals from Cilento-Italy 148
Autosomal recessive limb-girdle muscular dystrophy, LGMD2F, is caused by a mutation in the delta-sarcoglycan gene. 145
Longevity-Associated Variant of BPIFB4 Mitigates Monocyte-Mediated Acquired Immune Response 145
GRN deletion in familial frontotemporal dementia showing association with clinical variability in 3 familial cases 143
APOE Alleles and Extreme Human Longevity 143
Corrigendum to “A bioavailability study on microbeads and nanoliposomes fabricated by dense carbon dioxide technologies using human-primary monocytes and flow cytometry assay” (International Journal of Pharmaceutics (2019) 570, (S0378517319307318), (10.1016/j.ijpharm.2019.118686)) 143
Association of rs2200733 at 4q25 with atrial flutter/fibrillation diseases in an Italian population. 140
Resveratrol Improves Vascular Function in Patients With Hypertension and Dyslipidemia by Modulating NO Metabolism. 140
A novel p53 mutant in human breast cancer revealed by multiple SSCP analysis. 139
Morus alba extract modulates blood pressure homeostasis through eNOS signaling 139
CaMK4 Gene Deletion Induces Hypertension 139
A DNA methylation fingerprint of 1628 human samples. 137
Identification of a novel sarcoglycan gene at 5q33 encoding a sarcolemmal 35 kDa glycoprotein. 137
Targeting the ASMase/S1P pathway protects from sortilin-evoked vascular damage in hypertension 137
Association of the FOXO3A locus with extreme longevity in a southern Italian centenarian study. 136
Exome sequencing of a family with lone, autosomal dominant atrial flutter identifies a rare variation in ABCB4 significantly enriched in cases 135
A caccia dei Geni della Longevita' 134
Targeting Nitric Oxide with Natural Derived Compounds as a Therapeutic Strategy in Vascular Diseases 132
A model of evolutionary selection: The cardiovascular protective function of the longevity associated variant of BPIFB4 132
A genome-wide scan for linkage to human exceptional longevity identifies a locus on chromosome 4. 131
Pathogenic Huntingtin Repeat Expansions in Patients with Frontotemporal Dementia and Amyotrophic Lateral Sclerosis 131
Genetic Analysis Reveals a Longevity-Associated Protein Modulating Endothelial Function and Angiogenesis 130
Association of immunoglobulin GM allotypes with longevity in long-living individuals from Southern Italy 130
Multi-criteria decision making approaches for quality control of genome-wide association studies. 126
SIRT1 pharmacological activation rescues vascular dysfunction and prevents thrombosis in MTHFR deficiency 125
Old, Nonagenarians, and Centenarians in Cilento, Italy and the Association of Lifespan with the Level of Some Physicochemical Elements in Tap Drinking Water 122
Butyrate as bioactive human milk protective component against food allergy 122
Limitations and risks of meta-analyses of longevity studies 121
New Nutraceutical Combination Reduces Blood Pressure and Improves Exercise Capacity in Hypertensive Patients Via a Nitric Oxide-Dependent Mechanism 119
Gamma1- and gamma2-syntrophins, two novel dystrophin-binding proteins localized in neuronal cells. 117
RNA Editing Genes Associated with Extreme Old Age in Humans and with Lifespan in C. elegans 117
Frontotemporal dementia and its subtypes: a genome-wide association study. 117
Stem cell and macrophage roles in skeletal muscle regenerative medicine 117
Vascular ageing: The role of oxidative stress. 116
Immune-related genetic enrichment in frontotemporal dementia: An analysis of genome-wide association studies 116
The longevity-associated variant of BPIFB4 improves a CXCR4-mediated striatum–microglia crosstalk preventing disease progression in a mouse model of Huntington’s disease 116
Lipid metabolism and diet: possible mechanisms of slow aging. 115
Blood biomarkers role in acute ischemic stroke patients: higher is worse or better? 115
Clinical Status, Nutritional Behavior, and Lifestyle, and Determinants of Community Well-Being of Patients from the Perspective of Physicians: A Cross-Sectional Study of Young Older Adults, Nonagenarians, and Centenarians in Salerno and Province, Italy 114
Pentraxin 3 induces vascular endothelial dysfunction through a P-selectin/matrix metalloproteinase-1 pathway 114
The Role of BPIFB4 in Immune System and Cardiovascular Disease: The Lesson from Centenarians 114
The genetics of aging. 113
Interaction between Diet and Genes on LongevityNutritional and Metabolic Bases of Cardiovascular Disease 108
BPIFB4 missense variants associate with exceptional longevity in independent populations and influence cell signaling 108
A donor splice site mutation in CISD2 generates multiple truncated, non-functional isoforms in Wolfram syndrome type 2 patients 108
Four Genome-Wide Association Studies Identify New Extreme Longevity Variants 108
Genetic signature of exceptional longevity 107
The Genetics Applied to Centenarians 107
Genetic Loci Indicative of Propensity for Longevity and methods for Identifying Propensity for Age-Related Disease 107
A novel human serine-threonine phosphatase related to the Drosophila retinal degeneration C (rdgC) gene is selectively expressed in sensory neurons of neural crest origin. 107
Identification of evolutionarily conserved gene networks mediating neurodegenerative dementia 106
SARS-CoV-2 Lysate Stimulation Impairs the Release of Platelet-like Particles and Megakaryopoiesis in the MEG-01 Cell Line 104
The application of genetics approaches to the study of exceptional longevity in humans: potential and limitations 102
Immunomodulatory activity of Humulus lupulus bitter acids fraction: Enhancement of natural killer cells function by NKp44 activating receptor stimulation 101
Role of cytosolic calcium-dependent phospholipase A2 in Alzheimer's disease pathogenesis. 100
Effects of Human LAV-BPIFB4 Gene Therapy on the Epigenetic Clock and Health of Aged Mice 98
Meta-analysis of genetic variants associated with human exceptional longevity. 98
S -nitrosylation drives cell senescence and aging in mammals by controlling mitochondrial dynamics and mitophagy 98
Effects of FOXO3 Polymorphisms on Survival to Extreme Longevity in Four Centenarian Studies 97
Fatty acid profile of erythrocyte membranes as possible biomarker of longevity. 95
Identification of a DNA binding protein cooperating with estrogen receptor as RIZ (retinoblastoma interacting zinc finger protein). 93
Candidate gene study of FOXO1, FOXO4, and FOXO6 reveals no association with human longevity in Germans. 92
Totale 21.175
Categoria #
all - tutte 73.712
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 73.712


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022857 0 3 1 18 28 15 7 52 122 102 124 385
2022/20231.347 143 84 93 143 188 282 8 124 190 6 57 29
2023/2024622 46 97 49 26 60 63 41 33 14 36 17 140
2024/20252.028 65 33 57 90 67 243 284 222 369 105 225 268
2025/202616.500 1.396 4.236 3.209 575 932 402 1.309 271 2.316 695 280 879
2026/2027465 279 186 0 0 0 0 0 0 0 0 0 0
Totale 25.900