PUCA, Annibale Alessandro
 Distribuzione geografica
Continente #
AS - Asia 12.111
NA - Nord America 8.798
EU - Europa 5.177
SA - Sud America 748
Continente sconosciuto - Info sul continente non disponibili 419
AF - Africa 118
OC - Oceania 15
Totale 27.386
Nazione #
US - Stati Uniti d'America 8.525
HK - Hong Kong 7.950
FI - Finlandia 1.961
SG - Singapore 1.936
IT - Italia 1.485
CN - Cina 838
VN - Vietnam 647
BR - Brasile 564
RU - Federazione Russa 387
UA - Ucraina 384
DE - Germania 241
IE - Irlanda 171
FR - Francia 157
KR - Corea 147
CA - Canada 135
TR - Turchia 129
BD - Bangladesh 105
IN - India 105
GB - Regno Unito 98
AR - Argentina 80
SE - Svezia 71
MX - Messico 50
NL - Olanda 43
ES - Italia 37
JP - Giappone 35
AT - Austria 33
ID - Indonesia 33
PL - Polonia 32
ZA - Sudafrica 31
IQ - Iraq 28
PK - Pakistan 23
UZ - Uzbekistan 21
CO - Colombia 20
EC - Ecuador 20
VE - Venezuela 18
JM - Giamaica 17
MA - Marocco 16
PY - Paraguay 16
SA - Arabia Saudita 15
MY - Malesia 14
CZ - Repubblica Ceca 13
EG - Egitto 12
TT - Trinidad e Tobago 12
CL - Cile 11
KE - Kenya 11
AU - Australia 10
HN - Honduras 10
JO - Giordania 10
UY - Uruguay 10
AZ - Azerbaigian 9
CH - Svizzera 9
CR - Costa Rica 9
ET - Etiopia 9
LT - Lituania 8
NI - Nicaragua 8
TN - Tunisia 8
AE - Emirati Arabi Uniti 7
DK - Danimarca 7
PE - Perù 7
PH - Filippine 7
DO - Repubblica Dominicana 6
EU - Europa 6
LB - Libano 6
BE - Belgio 5
BY - Bielorussia 5
DZ - Algeria 5
IL - Israele 5
KZ - Kazakistan 5
LV - Lettonia 5
OM - Oman 5
SV - El Salvador 5
BB - Barbados 4
GR - Grecia 4
GT - Guatemala 4
NG - Nigeria 4
NP - Nepal 4
PA - Panama 4
TH - Thailandia 4
AL - Albania 3
HU - Ungheria 3
LA - Repubblica Popolare Democratica del Laos 3
PS - Palestinian Territory 3
SN - Senegal 3
AF - Afghanistan, Repubblica islamica di 2
AM - Armenia 2
BA - Bosnia-Erzegovina 2
BG - Bulgaria 2
BH - Bahrain 2
BW - Botswana 2
CW - ???statistics.table.value.countryCode.CW??? 2
EE - Estonia 2
GA - Gabon 2
GN - Guinea 2
IR - Iran 2
KW - Kuwait 2
MD - Moldavia 2
MK - Macedonia 2
NZ - Nuova Zelanda 2
RO - Romania 2
SC - Seychelles 2
Totale 26.940
Città #
Hong Kong 7.938
Helsinki 1.866
San Jose 1.030
Ann Arbor 990
Singapore 900
Ashburn 552
Chandler 533
Milan 517
Princeton 506
Jacksonville 469
Dallas 397
Council Bluffs 336
Wilmington 315
Woodbridge 273
Dong Ket 253
Beijing 194
Dublin 162
Ho Chi Minh City 152
Rome 142
The Dalles 139
Lauterbourg 136
Nanjing 129
Naples 124
New York 115
Andover 112
Los Angeles 108
Santa Clara 102
Izmir 101
Houston 88
Moscow 84
Boardman 82
Hanoi 79
Munich 77
Salerno 76
São Paulo 71
Pellezzano 60
Memphis 56
Figino 46
Dearborn 45
Fairfield 43
Chicago 38
Nuremberg 37
Montreal 36
Phoenix 36
Denver 34
Tokyo 34
Brooklyn 33
Norwalk 33
Shenyang 33
Chennai 32
Orem 32
Atlanta 30
Columbus 29
Hebei 29
Seattle 29
Changsha 27
Warsaw 27
Jiaxing 26
London 26
Haiphong 25
Nanchang 25
Tianjin 25
Redwood City 24
Turku 24
Stockholm 23
Washington 22
Toronto 21
San Diego 20
Tashkent 20
Turin 20
Da Nang 19
Mexico City 19
San Francisco 19
Bari 17
Fisciano 17
Philadelphia 17
Amsterdam 16
Frankfurt am Main 16
Jinan 16
Boston 15
Johannesburg 15
Falls Church 14
Manchester 14
Mestre 14
Rio de Janeiro 13
Sarno 13
Mercato San Severino 12
Miami 12
Ottawa 12
Brno 11
Campinas 11
Curitiba 11
Düsseldorf 11
Las Vegas 11
Belo Horizonte 10
Buffalo 10
Charlotte 10
Kingston 10
Nizhniy Novgorod 10
Quito 10
Totale 20.653
Nome #
A bioavailability study on microbeads and nanoliposomes fabricated by dense carbon dioxide technologies using human-primary monocytes and flow cytometry assay 2.067
Diet and Longevity Phenotype 1.221
Circulating BPIFB4 Levels Associate With and Influence the Abundance of Reparative Monocytes and Macrophages in Long Living Individuals 607
The Longevity-Associated Variant of BPIFB4 Reduces Senescence in Glioma Cells and in Patients’ Lymphocytes Favoring Chemotherapy Efficacy 544
The longevity-associated BPIFB4 gene guarantees vascular homeostasis and immune protection through platelets 541
High TARC plasma levels confer protection to long living individuals by inducing M2 profile 523
Serum BPIFB4 levels classify health status in long-living individuals 521
Antioxidant effects of resveratrol in cardiovascular, cerebral and metabolic diseases. 493
A G613A missense in the Hutchinson's progeria lamin A/C gene causes a lone, autosomal dominant atrioventricular block 478
Klebsiella pneumoniae-OMVs activate death-signaling pathways in Human Bronchial Epithelial Host Cells (BEAS-2B) 442
Genetic signatures of exceptional longevity in humans. 380
Rac1 pharmacological inhibition rescues human endothelial dysfunction 377
LAV-BPIFB4 isoform modulates eNOS signaling through Ca2+/PKC-alpha dependent mechanism 370
Centenarians as a model to discover genetic and epigenetic signatures of healthy ageing 370
LAV-BPIFB4 associates with reduced frailty in humans and its transfer prevents frailty progression in old mice 359
SLITRK2, an X-linked modifier of the age at onset in C9orf72 frontotemporal lobar degeneration 343
Transfer of the longevity-associated variant of BPIFB4 gene rejuvenates immune system and vasculature by a reduction of CD38+ macrophages and NAD+ decline 331
A rare genetic variant of BPIFB4 predisposes to high blood pressure via impairment of nitric oxide signaling 294
Gender Differences Associated with the Prognostic Value of BPIFB4 in COVID-19 Patients: A Single-Center Preliminary Study 244
Longevity-associated BPIFB4 gene counteracts the inflammatory signaling 239
Single systemic transfer of a human gene associated with exceptional longevity halts the progression of atherosclerosis and inflammation in ApoE knockout mice through a CXCR4-mediated mechanism 231
Sortilin evokes endothelial dysfunction and arterial hypertension through the dysregulation of sphingolipid metabolism and oxidative stress 208
Transfer of a human gene variant associated with exceptional longevity improves cardiac function in obese type 2 diabetic mice through induction of the SDF-1/CXCR4 signalling pathway 207
Optimizing mRNA delivery: A microfluidic exploration of DOTMA vs. DOTAP lipid nanoparticles for GFP expression on human PBMCs and THP-1 cell line 205
Polymorphisms of the antiapoptotic protein bag3 may play a role in the pathogenesis of tako-tsubo cardiomyopathy 204
Bisphenol A induces DNA damage in cells exerting immune surveillance functions at peripheral and central level 203
Risk factors and acute ischemic stroke subtypes 201
The anti-ageing molecule sirt1 mediates beneficial effects of cardiac rehabilitation 193
Innate immunity and cellular senescence: The good and the bad in the developmental and aged brain 191
The inflammatory protein Pentraxin 3 in cardiovascular disease 175
BPIFB4 Circulating Levels and Its Prognostic Relevance in COVID-19 172
Association Study on Long-Living Individuals from Southern Italy Identifies rs10491334 in the CAMKIV Gene That Regulates Survival Proteins. 170
Human platelets and megakaryocytes express the BPIFB4 protein and their stimulation with the recombinant Longevity-associated variant LAV-BPIFB4 displays anti-aggregating activity 166
A genome-wide screening and SNPs-to-genes approach to identify novel genetic risk factors associated with frontotemporal dementia 166
Ankyrin-B syndrome: enhanced cardiac function balanced by risk of cardiac death and premature senescence. 166
Brain diseases and tumorigenesis: The good and bad cops of pentraxin3 165
Assessment of the 9p21.3 locus in severity of coronary artery disease in the presence and absence of type 2 diabetes. 161
CaMK4 Gene Deletion Induces Hypertension 159
Endothelial nitric oxide synthase, vascular integrity and human exceptional longevity 157
APOE Alleles and Extreme Human Longevity 156
The expression of the BPIFB4 and CXCR4 associates with sustained health in long-living individuals from Cilento-Italy 155
GRN deletion in familial frontotemporal dementia showing association with clinical variability in 3 familial cases 154
Autosomal recessive limb-girdle muscular dystrophy, LGMD2F, is caused by a mutation in the delta-sarcoglycan gene. 151
Morus alba extract modulates blood pressure homeostasis through eNOS signaling 151
Longevity-Associated Variant of BPIFB4 Mitigates Monocyte-Mediated Acquired Immune Response 151
Resveratrol Improves Vascular Function in Patients With Hypertension and Dyslipidemia by Modulating NO Metabolism. 150
Corrigendum to “A bioavailability study on microbeads and nanoliposomes fabricated by dense carbon dioxide technologies using human-primary monocytes and flow cytometry assay” (International Journal of Pharmaceutics (2019) 570, (S0378517319307318), (10.1016/j.ijpharm.2019.118686)) 149
Association of rs2200733 at 4q25 with atrial flutter/fibrillation diseases in an Italian population. 146
A genome-wide scan for linkage to human exceptional longevity identifies a locus on chromosome 4. 146
A novel p53 mutant in human breast cancer revealed by multiple SSCP analysis. 144
Identification of a novel sarcoglycan gene at 5q33 encoding a sarcolemmal 35 kDa glycoprotein. 143
Targeting the ASMase/S1P pathway protects from sortilin-evoked vascular damage in hypertension 143
A DNA methylation fingerprint of 1628 human samples. 142
Association of the FOXO3A locus with extreme longevity in a southern Italian centenarian study. 141
Exome sequencing of a family with lone, autosomal dominant atrial flutter identifies a rare variation in ABCB4 significantly enriched in cases 141
BPIFB4 missense variants associate with exceptional longevity in independent populations and influence cell signaling 140
Genetic signature of exceptional longevity 139
A caccia dei Geni della Longevita' 139
Genetic Analysis Reveals a Longevity-Associated Protein Modulating Endothelial Function and Angiogenesis 138
A model of evolutionary selection: The cardiovascular protective function of the longevity associated variant of BPIFB4 138
Old, Nonagenarians, and Centenarians in Cilento, Italy and the Association of Lifespan with the Level of Some Physicochemical Elements in Tap Drinking Water 137
Targeting Nitric Oxide with Natural Derived Compounds as a Therapeutic Strategy in Vascular Diseases 137
Pathogenic Huntingtin Repeat Expansions in Patients with Frontotemporal Dementia and Amyotrophic Lateral Sclerosis 137
Association of immunoglobulin GM allotypes with longevity in long-living individuals from Southern Italy 136
Butyrate as bioactive human milk protective component against food allergy 133
The Role of BPIFB4 in Immune System and Cardiovascular Disease: The Lesson from Centenarians 133
Immune-related genetic enrichment in frontotemporal dementia: An analysis of genome-wide association studies 132
Multi-criteria decision making approaches for quality control of genome-wide association studies. 131
Vascular ageing: The role of oxidative stress. 131
SIRT1 pharmacological activation rescues vascular dysfunction and prevents thrombosis in MTHFR deficiency 130
Lipid metabolism and diet: possible mechanisms of slow aging. 130
The longevity-associated variant of BPIFB4 improves a CXCR4-mediated striatum–microglia crosstalk preventing disease progression in a mouse model of Huntington’s disease 129
Limitations and risks of meta-analyses of longevity studies 127
New Nutraceutical Combination Reduces Blood Pressure and Improves Exercise Capacity in Hypertensive Patients Via a Nitric Oxide-Dependent Mechanism 127
Frontotemporal dementia and its subtypes: a genome-wide association study. 125
Effects of Human LAV-BPIFB4 Gene Therapy on the Epigenetic Clock and Health of Aged Mice 124
RNA Editing Genes Associated with Extreme Old Age in Humans and with Lifespan in C. elegans 124
Four Genome-Wide Association Studies Identify New Extreme Longevity Variants 123
Blood biomarkers role in acute ischemic stroke patients: higher is worse or better? 122
Gamma1- and gamma2-syntrophins, two novel dystrophin-binding proteins localized in neuronal cells. 121
Genetic Loci Indicative of Propensity for Longevity and methods for Identifying Propensity for Age-Related Disease 121
Stem cell and macrophage roles in skeletal muscle regenerative medicine 121
Pentraxin 3 induces vascular endothelial dysfunction through a P-selectin/matrix metalloproteinase-1 pathway 119
Clinical Status, Nutritional Behavior, and Lifestyle, and Determinants of Community Well-Being of Patients from the Perspective of Physicians: A Cross-Sectional Study of Young Older Adults, Nonagenarians, and Centenarians in Salerno and Province, Italy 118
The genetics of aging. 118
A novel human serine-threonine phosphatase related to the Drosophila retinal degeneration C (rdgC) gene is selectively expressed in sensory neurons of neural crest origin. 117
Interaction between Diet and Genes on LongevityNutritional and Metabolic Bases of Cardiovascular Disease 114
Identification of evolutionarily conserved gene networks mediating neurodegenerative dementia 114
A donor splice site mutation in CISD2 generates multiple truncated, non-functional isoforms in Wolfram syndrome type 2 patients 114
Taste receptors, innate immunity and longevity: The case of TAS2R16 gene 113
The Genetics Applied to Centenarians 111
SARS-CoV-2 Lysate Stimulation Impairs the Release of Platelet-like Particles and Megakaryopoiesis in the MEG-01 Cell Line 109
Effects of FOXO3 Polymorphisms on Survival to Extreme Longevity in Four Centenarian Studies 109
Immunomodulatory activity of Humulus lupulus bitter acids fraction: Enhancement of natural killer cells function by NKp44 activating receptor stimulation 109
The application of genetics approaches to the study of exceptional longevity in humans: potential and limitations 108
Exceptional familial clustering for extreme longevity in humans. 106
Role of cytosolic calcium-dependent phospholipase A2 in Alzheimer's disease pathogenesis. 106
S -nitrosylation drives cell senescence and aging in mammals by controlling mitochondrial dynamics and mitophagy 106
Meta-analysis of genetic variants associated with human exceptional longevity. 105
Distinct DNA methylomes of newborns and centenarians. 104
Totale 22.132
Categoria #
all - tutte 78.379
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 78.379


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022853 0 0 0 18 28 15 7 52 122 102 124 385
2022/20231.347 143 84 93 143 188 282 8 124 190 6 57 29
2023/2024622 46 97 49 26 60 63 41 33 14 36 17 140
2024/20252.028 65 33 57 90 67 243 284 222 369 105 225 268
2025/202616.500 1.396 4.236 3.209 575 932 402 1.309 271 2.316 695 280 879
2026/20271.951 279 245 751 676 0 0 0 0 0 0 0 0
Totale 27.386