PUCA, Annibale Alessandro
 Distribuzione geografica
Continente #
AS - Asia 9.860
NA - Nord America 5.131
EU - Europa 2.019
SA - Sud America 419
AF - Africa 45
OC - Oceania 15
Continente sconosciuto - Info sul continente non disponibili 8
Totale 17.497
Nazione #
HK - Hong Kong 7.838
US - Stati Uniti d'America 5.062
SG - Singapore 758
CN - Cina 576
IT - Italia 570
RU - Federazione Russa 373
UA - Ucraina 371
BR - Brasile 363
VN - Vietnam 321
DE - Germania 216
IE - Irlanda 167
KR - Corea 138
FI - Finlandia 106
TR - Turchia 103
SE - Svezia 58
CA - Canada 38
GB - Regno Unito 37
IN - India 35
AT - Austria 30
AR - Argentina 25
NL - Olanda 25
BD - Bangladesh 21
MX - Messico 16
ES - Italia 14
CZ - Repubblica Ceca 13
ID - Indonesia 13
PL - Polonia 12
AU - Australia 10
EC - Ecuador 8
MA - Marocco 8
KE - Kenya 7
UZ - Uzbekistan 7
ZA - Sudafrica 7
EU - Europa 6
IQ - Iraq 6
VE - Venezuela 6
BE - Belgio 5
EG - Egitto 5
JP - Giappone 5
MY - Malesia 5
PK - Pakistan 5
PY - Paraguay 5
CH - Svizzera 4
FR - Francia 4
NI - Nicaragua 4
UY - Uruguay 4
AE - Emirati Arabi Uniti 3
CO - Colombia 3
LA - Repubblica Popolare Democratica del Laos 3
PE - Perù 3
TN - Tunisia 3
AF - Afghanistan, Repubblica islamica di 2
BW - Botswana 2
CL - Cile 2
DK - Danimarca 2
DZ - Algeria 2
GR - Grecia 2
HN - Honduras 2
IL - Israele 2
IR - Iran 2
KZ - Kazakistan 2
LB - Libano 2
NG - Nigeria 2
NP - Nepal 2
NZ - Nuova Zelanda 2
OM - Oman 2
RO - Romania 2
SA - Arabia Saudita 2
TT - Trinidad e Tobago 2
XK - ???statistics.table.value.countryCode.XK??? 2
AL - Albania 1
AM - Armenia 1
BA - Bosnia-Erzegovina 1
BB - Barbados 1
BZ - Belize 1
CU - Cuba 1
CV - Capo Verde 1
DO - Repubblica Dominicana 1
EE - Estonia 1
GA - Gabon 1
GE - Georgia 1
GN - Guinea 1
IS - Islanda 1
KH - Cambogia 1
KW - Kuwait 1
LC - Santa Lucia 1
LI - Liechtenstein 1
LT - Lituania 1
LV - Lettonia 1
MG - Madagascar 1
MK - Macedonia 1
ML - Mali 1
MU - Mauritius 1
NR - Nauru 1
PA - Panama 1
PH - Filippine 1
PS - Palestinian Territory 1
RW - Ruanda 1
SN - Senegal 1
TV - Tuvalu 1
Totale 17.493
Città #
Hong Kong 7.832
Ann Arbor 990
Chandler 533
Princeton 505
Jacksonville 463
Dallas 373
Wilmington 309
Woodbridge 273
Dong Ket 253
Singapore 244
Ashburn 161
Dublin 159
Nanjing 127
Andover 112
Naples 103
Izmir 101
Beijing 96
Moscow 83
Boardman 81
Munich 77
Salerno 72
Houston 64
Pellezzano 60
Los Angeles 48
Dearborn 45
Fairfield 41
São Paulo 34
Shenyang 33
Ho Chi Minh City 32
The Dalles 32
New York 31
Nuremberg 31
Norwalk 30
Hebei 29
Changsha 27
Columbus 26
Jiaxing 26
Milan 25
Nanchang 25
Tianjin 25
Redwood City 24
Turku 24
Seattle 23
San Diego 17
Jinan 16
Brooklyn 15
Washington 15
Falls Church 14
Mestre 14
Rome 14
Council Bluffs 13
Fisciano 13
Chennai 12
Mercato San Severino 12
Brno 11
Düsseldorf 11
Hanoi 11
Helsinki 11
Montreal 11
Sarno 11
Warsaw 11
Nizhniy Novgorod 10
Seoul 10
Stockholm 10
Curitiba 9
Gatchina 9
Rio de Janeiro 9
San Francisco 9
Santa Clara 9
Vienna 9
Chicago 8
Ottawa 8
Boston 7
Guangzhou 7
London 7
Napoli 7
Salvador 7
Tashkent 7
Zhengzhou 7
Atlanta 6
Belo Horizonte 6
Brasília 6
Cambridge 6
Campinas 6
Haiphong 6
Hangzhou 6
Kunming 6
Melbourne 6
Springfield 6
St Petersburg 6
Utrecht 6
Bari 5
Casablanca 5
Guarulhos 5
Juiz de Fora 5
Mexico City 5
Nairobi 5
Ningbo 5
Quito 5
Sant'Antonio Abate 5
Totale 14.180
Nome #
Diet and Longevity Phenotype 1.182
Circulating BPIFB4 Levels Associate With and Influence the Abundance of Reparative Monocytes and Macrophages in Long Living Individuals 551
The Longevity-Associated Variant of BPIFB4 Reduces Senescence in Glioma Cells and in Patients’ Lymphocytes Favoring Chemotherapy Efficacy 497
Serum BPIFB4 levels classify health status in long-living individuals 481
The longevity-associated BPIFB4 gene guarantees vascular homeostasis and immune protection through platelets 457
High TARC plasma levels confer protection to long living individuals by inducing M2 profile 454
Antioxidant effects of resveratrol in cardiovascular, cerebral and metabolic diseases. 436
A G613A missense in the Hutchinson's progeria lamin A/C gene causes a lone, autosomal dominant atrioventricular block 428
Klebsiella pneumoniae-OMVs activate death-signaling pathways in Human Bronchial Epithelial Host Cells (BEAS-2B) 376
Genetic signatures of exceptional longevity in humans. 343
Rac1 pharmacological inhibition rescues human endothelial dysfunction 336
LAV-BPIFB4 isoform modulates eNOS signaling through Ca2+/PKC-alpha dependent mechanism 334
Centenarians as a model to discover genetic and epigenetic signatures of healthy ageing 328
LAV-BPIFB4 associates with reduced frailty in humans and its transfer prevents frailty progression in old mice 316
SLITRK2, an X-linked modifier of the age at onset in C9orf72 frontotemporal lobar degeneration 304
Transfer of the longevity-associated variant of BPIFB4 gene rejuvenates immune system and vasculature by a reduction of CD38+ macrophages and NAD+ decline 257
A rare genetic variant of BPIFB4 predisposes to high blood pressure via impairment of nitric oxide signaling 226
Longevity-associated BPIFB4 gene counteracts the inflammatory signaling 191
Single systemic transfer of a human gene associated with exceptional longevity halts the progression of atherosclerosis and inflammation in ApoE knockout mice through a CXCR4-mediated mechanism 183
Gender Differences Associated with the Prognostic Value of BPIFB4 in COVID-19 Patients: A Single-Center Preliminary Study 173
Transfer of a human gene variant associated with exceptional longevity improves cardiac function in obese type 2 diabetic mice through induction of the SDF-1/CXCR4 signalling pathway 166
Sortilin evokes endothelial dysfunction and arterial hypertension through the dysregulation of sphingolipid metabolism and oxidative stress 162
Risk factors and acute ischemic stroke subtypes 153
Polymorphisms of the antiapoptotic protein bag3 may play a role in the pathogenesis of tako-tsubo cardiomyopathy 153
The anti-ageing molecule sirt1 mediates beneficial effects of cardiac rehabilitation 153
A bioavailability study on microbeads and nanoliposomes fabricated by dense carbon dioxide technologies using human-primary monocytes and flow cytometry assay 148
Innate immunity and cellular senescence: The good and the bad in the developmental and aged brain 142
The inflammatory protein Pentraxin 3 in cardiovascular disease 138
Brain diseases and tumorigenesis: The good and bad cops of pentraxin3 127
Association Study on Long-Living Individuals from Southern Italy Identifies rs10491334 in the CAMKIV Gene That Regulates Survival Proteins. 127
GRN deletion in familial frontotemporal dementia showing association with clinical variability in 3 familial cases 117
Ankyrin-B syndrome: enhanced cardiac function balanced by risk of cardiac death and premature senescence. 115
Assessment of the 9p21.3 locus in severity of coronary artery disease in the presence and absence of type 2 diabetes. 114
The expression of the BPIFB4 and CXCR4 associates with sustained health in long-living individuals from Cilento-Italy 113
Bisphenol A induces DNA damage in cells exerting immune surveillance functions at peripheral and central level 113
Identification of a novel sarcoglycan gene at 5q33 encoding a sarcolemmal 35 kDa glycoprotein. 112
Endothelial nitric oxide synthase, vascular integrity and human exceptional longevity 112
Human platelets and megakaryocytes express the BPIFB4 protein and their stimulation with the recombinant Longevity-associated variant LAV-BPIFB4 displays anti-aggregating activity 111
Morus alba extract modulates blood pressure homeostasis through eNOS signaling 110
A genome-wide screening and SNPs-to-genes approach to identify novel genetic risk factors associated with frontotemporal dementia 107
Resveratrol Improves Vascular Function in Patients With Hypertension and Dyslipidemia by Modulating NO Metabolism. 103
CaMK4 Gene Deletion Induces Hypertension 103
Exome sequencing of a family with lone, autosomal dominant atrial flutter identifies a rare variation in ABCB4 significantly enriched in cases 102
Targeting Nitric Oxide with Natural Derived Compounds as a Therapeutic Strategy in Vascular Diseases 101
Limitations and risks of meta-analyses of longevity studies 98
Targeting the ASMase/S1P pathway protects from sortilin-evoked vascular damage in hypertension 98
Autosomal recessive limb-girdle muscular dystrophy, LGMD2F, is caused by a mutation in the delta-sarcoglycan gene. 97
Pathogenic Huntingtin Repeat Expansions in Patients with Frontotemporal Dementia and Amyotrophic Lateral Sclerosis 97
Genetic Analysis Reveals a Longevity-Associated Protein Modulating Endothelial Function and Angiogenesis 95
A model of evolutionary selection: The cardiovascular protective function of the longevity associated variant of BPIFB4 95
Association of rs2200733 at 4q25 with atrial flutter/fibrillation diseases in an Italian population. 94
A caccia dei Geni della Longevita' 94
Multi-criteria decision making approaches for quality control of genome-wide association studies. 93
RNA Editing Genes Associated with Extreme Old Age in Humans and with Lifespan in C. elegans 91
Longevity-Associated Variant of BPIFB4 Mitigates Monocyte-Mediated Acquired Immune Response 91
A DNA methylation fingerprint of 1628 human samples. 89
A novel p53 mutant in human breast cancer revealed by multiple SSCP analysis. 89
Association of the FOXO3A locus with extreme longevity in a southern Italian centenarian study. 88
BPIFB4 Circulating Levels and Its Prognostic Relevance in COVID-19 88
The genetics of aging. 86
Vascular ageing: The role of oxidative stress. 86
Pentraxin 3 induces vascular endothelial dysfunction through a P-selectin/matrix metalloproteinase-1 pathway 85
null 85
Lipid metabolism and diet: possible mechanisms of slow aging. 82
Interaction between Diet and Genes on LongevityNutritional and Metabolic Bases of Cardiovascular Disease 82
BPIFB4 missense variants associate with exceptional longevity in independent populations and influence cell signaling 82
Blood biomarkers role in acute ischemic stroke patients: higher is worse or better? 82
A genome-wide scan for linkage to human exceptional longevity identifies a locus on chromosome 4. 82
Corrigendum to “A bioavailability study on microbeads and nanoliposomes fabricated by dense carbon dioxide technologies using human-primary monocytes and flow cytometry assay” (International Journal of Pharmaceutics (2019) 570, (S0378517319307318), (10.1016/j.ijpharm.2019.118686)) 80
The Genetics Applied to Centenarians 79
Genetic Loci Indicative of Propensity for Longevity and methods for Identifying Propensity for Age-Related Disease 78
Frontotemporal dementia and its subtypes: a genome-wide association study. 78
Association of immunoglobulin GM allotypes with longevity in long-living individuals from Southern Italy 78
SIRT1 pharmacological activation rescues vascular dysfunction and prevents thrombosis in MTHFR deficiency 76
APOE Alleles and Extreme Human Longevity 76
Four Genome-Wide Association Studies Identify New Extreme Longevity Variants 76
Genetic signature of exceptional longevity 75
Effects of Human LAV-BPIFB4 Gene Therapy on the Epigenetic Clock and Health of Aged Mice 74
Meta-analysis of genetic variants associated with human exceptional longevity. 73
Stem cell and macrophage roles in skeletal muscle regenerative medicine 72
Old, Nonagenarians, and Centenarians in Cilento, Italy and the Association of Lifespan with the Level of Some Physicochemical Elements in Tap Drinking Water 70
Clinical Status, Nutritional Behavior, and Lifestyle, and Determinants of Community Well-Being of Patients from the Perspective of Physicians: A Cross-Sectional Study of Young Older Adults, Nonagenarians, and Centenarians in Salerno and Province, Italy 69
Role of cytosolic calcium-dependent phospholipase A2 in Alzheimer's disease pathogenesis. 69
A donor splice site mutation in CISD2 generates multiple truncated, non-functional isoforms in Wolfram syndrome type 2 patients 69
New Nutraceutical Combination Reduces Blood Pressure and Improves Exercise Capacity in Hypertensive Patients Via a Nitric Oxide-Dependent Mechanism 69
Candidate gene study of FOXO1, FOXO4, and FOXO6 reveals no association with human longevity in Germans. 67
The application of genetics approaches to the study of exceptional longevity in humans: potential and limitations 67
Correlations between progression of coronary artery disease and circulating endothelial progenitor cells. 66
A novel human serine-threonine phosphatase related to the Drosophila retinal degeneration C (rdgC) gene is selectively expressed in sensory neurons of neural crest origin. 66
Butyrate as bioactive human milk protective component against food allergy 64
Unexpectedly low mutation rates in beta-myosin heavy chain and cardiac myosin binding protein genes in Italian patients with hypertrophic cardiomyopathy. 63
Lack of sodium channel mutation in an Italian family with paramyotonia congenita. 63
The genetics of exceptional human longevity. 63
Fatty acid profile of erythrocyte membranes as possible biomarker of longevity. 62
Identification and characterization of a novel member of the dystrobrevin gene family. 62
Identification of a DNA binding protein cooperating with estrogen receptor as RIZ (retinoblastoma interacting zinc finger protein). 62
Gamma1- and gamma2-syntrophins, two novel dystrophin-binding proteins localized in neuronal cells. 61
Gene redundancies in the dystrophin-associated protein complex. 61
null 60
Haplotype-based identification of a microsomal transfer protein marker associated with the human lifespan. 59
Totale 15.211
Categoria #
all - tutte 54.664
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 54.664


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021739 0 0 0 10 88 105 90 4 82 11 78 271
2021/2022862 5 3 1 18 28 15 7 52 122 102 124 385
2022/20231.347 143 84 93 143 188 282 8 124 190 6 57 29
2023/2024622 46 97 49 26 60 63 41 33 14 36 17 140
2024/20252.028 65 33 57 90 67 243 284 222 369 105 225 268
2025/20268.959 1.396 4.236 3.209 118 0 0 0 0 0 0 0 0
Totale 17.894