CASTELLANO, Sabrina
 Distribuzione geografica
Continente #
NA - Nord America 5.166
EU - Europa 1.567
AS - Asia 1.073
SA - Sud America 120
AF - Africa 15
Continente sconosciuto - Info sul continente non disponibili 6
OC - Oceania 1
Totale 7.948
Nazione #
US - Stati Uniti d'America 5.154
IT - Italia 457
CN - Cina 389
UA - Ucraina 304
RU - Federazione Russa 290
SG - Singapore 264
VN - Vietnam 178
TR - Turchia 163
IE - Irlanda 135
DE - Germania 107
BR - Brasile 101
SE - Svezia 94
FI - Finlandia 69
FR - Francia 38
KR - Corea 28
IN - India 25
GB - Regno Unito 19
CZ - Repubblica Ceca 11
AR - Argentina 7
AT - Austria 7
NL - Olanda 7
EU - Europa 6
PE - Perù 6
GR - Grecia 5
HU - Ungheria 5
MA - Marocco 5
PK - Pakistan 5
CA - Canada 4
BG - Bulgaria 3
HK - Hong Kong 3
IL - Israele 3
PA - Panama 3
PL - Polonia 3
RO - Romania 3
BE - Belgio 2
CL - Cile 2
CO - Colombia 2
HR - Croazia 2
IR - Iran 2
JP - Giappone 2
MX - Messico 2
NO - Norvegia 2
SA - Arabia Saudita 2
TN - Tunisia 2
ZA - Sudafrica 2
AZ - Azerbaigian 1
BD - Bangladesh 1
BZ - Belize 1
CG - Congo 1
CH - Svizzera 1
CM - Camerun 1
DZ - Algeria 1
EC - Ecuador 1
EG - Egitto 1
ES - Italia 1
GH - Ghana 1
GT - Guatemala 1
ID - Indonesia 1
IQ - Iraq 1
JO - Giordania 1
KH - Cambogia 1
LU - Lussemburgo 1
NZ - Nuova Zelanda 1
PH - Filippine 1
PS - Palestinian Territory 1
RS - Serbia 1
SC - Seychelles 1
TT - Trinidad e Tobago 1
UZ - Uzbekistan 1
VE - Venezuela 1
Totale 7.948
Città #
Ann Arbor 1.456
Chandler 527
Woodbridge 503
Jacksonville 420
Houston 417
Princeton 384
Wilmington 310
Dong Ket 177
Salerno 167
Singapore 163
Izmir 160
Ashburn 159
Dublin 128
Beijing 101
Nanjing 82
Andover 78
Boardman 78
Moscow 52
Pellezzano 51
Dearborn 41
Fairfield 40
Hebei 34
Shenyang 25
Mestre 21
Nanchang 20
Pune 20
Philadelphia 17
Rome 17
Changsha 16
Fisciano 16
Norwalk 16
Jiaxing 15
Redwood City 15
Council Bluffs 13
Düsseldorf 13
Falls Church 13
Dallas 12
Guangzhou 12
Tianjin 12
Washington 12
Brno 11
Seattle 10
Cambridge 9
New York 9
Shanghai 9
Munich 8
São Paulo 8
Jinan 7
Los Angeles 7
Napoli 7
San Diego 7
Helsinki 6
Indiana 6
Munro 6
Renton 6
Tappahannock 6
Florence 5
Palermo 5
Sarno 5
Sorrento 5
Spinea 5
Edinburgh 4
Menlo Park 4
Naples 4
Stockholm 4
Cagliari 3
Campinas 3
Casoria 3
Catania 3
Clifton 3
Durham 3
Hefei 3
Lappeenranta 3
London 3
Marcianise 3
Messina 3
Mugnano del Cardinale 3
Newcastle upon Tyne 3
Néa Smýrni 3
Orange 3
Panama City 3
Santa Clara 3
Scafati 3
Vienna 3
Warsaw 3
Wuhan 3
Acerra 2
Aparecida de Goiânia 2
Athens 2
Atlanta 2
Bisamberg 2
Brasília 2
Brussels 2
Caivano 2
Calvisano 2
Chengdu 2
Chicago 2
Contrada 2
Domicella 2
Guaratinguetá 2
Totale 6.067
Nome #
A novel cell-permeable, selective and noncompetitive inhibitor of KAT3 histone acetyltransferases from a combined molecular pruning/classical isosterism approach 161
11C-ER176, a radioligand for 18-kDa translocator protein (TSPO), has adequate sensitivity to robustly image all three affinity genotypes in human brain 161
CARM1 modulators affect epigenome of stem cells and change morphology of nucleoli 139
A continuous-flow synthesis of 1,4-benzodiazepin-5-ones, privileged scaffolds for drug discovery 130
Unexpected fungicidal activity against Candida albicans of CPA18 and CPA109, novel azole compounds 126
Developing Spindlin1 small-molecule inhibitors by using protein microarrays 125
Microbiologia Molecolare e Cellulare 123
Identification of Small-Molecule Enhancers of Arginine Methylation Catalyzed by Coactivator-Associated Arginine Methyltransferase 1 123
A regioselective approach toward the synthesis of pharmacologically important quinone-containing heterocyclic systems 122
Regulation of USP37 Expression by REST-associated G9a-dependent Histone Methylation 116
Diversity through a branched reaction pathway: Generation of multicyclic scaffolds and identification of antimigratory agents 115
Modulation of the Activity of Histone Acetyltransferases by Long Chain Alkylidene-malonates (LoCAMs) 112
Constrained analogues of procaine as novel small molecule inhibitors of DNA methyltransferase-1. 111
Straightforward, Metal-free, and Stereoselective Synthesis of 9-Oxo- and 10-Hydroxy-2(E)-decenoic acids, Important Components of Honeybee (Apis mellifera) secretions 110
Design, Synthesis and Biological Evaluation of Carboxy Analogues of Arginine Methyltransferase Inhibitor 1 (AMI-1) 109
ChemInform Abstract: A Practical, Green, and Selective Approach Toward the Synthesis of Pharmacologically Important Quinone-Containing Heterocyclic Systems Using Alumina-Catalyzed Michael Addition Reaction 109
Identification of Structural Features of 2-Alkylidene-1,3-Dicarbonyl Derivatives that Induce Inhibition and/or Activation of Histone Acetyltransferases KAT3B/p300 and KAT2B/PCAF 109
ChemInform Abstract: Progress in the Development of Lysine Methyltransferase SETD8 Inhibitors 108
Antifungal activity of azole compounds CPA18 and CPA109 against azole-susceptible and -resistant strains of Candida albicans 104
Small-Molecule Inhibitors of Protein Geranylgeranyltransferase Type I 98
Structure–Activity Relationship Refinement and Further Assessment of 4-phenylquinazoline-2-carboxamide Translocator Protein (TSPO) Ligands as Antiproliferative Agents in Human Glioblastoma Tumors. 98
Azole antifungal agents related to naftifine and butenafine 96
A practical, green and selective approach toward the synthesis of pharmacologically important quinone-containing heterocyclic systems using alumina-catalyzed Michael addition reaction. 96
Highly efficient synthesis and chemical separation of 5-amino- and 7-amino-4-hydroxy-2-naphthoic acids 94
Synthesis and Biological Evaluation of 4-Phenylquinazoline-2-carboxamides Designed as a Novel Class of Potent Ligands of the Translocator Protein 94
Inside Cover: Identification of Structural Features of 2-Alkylidene-1,3-Dicarbonyl Derivatives that Induce Inhibition and/or Activation of Histone Acetyltransferases KAT3B/p300 and KAT2B/PCAF (ChemMedChem 1/2015) 94
p300/CBP-Associated Factor Selectively Regulates the Extinction of Conditioned Fear 93
Unprecedented synthesis of a novel amino quinone ring system via oxidative decarboxylation of quinone-based alpha,alpha-amino esters 93
ChemInform Abstract: Chemical Biology of Histone Acetyltransferase Natural Compounds Modulators 92
Progress in the Development of Lysine Methyltransferase SETD8 Inhibitors 92
Identification of PR-SET7 and EZH2 selective inhibitors inducing cell death in human leukemia U937 cells 91
ChemInform Abstract: A Continuous-Flow Synthesis of 1,4-Benzodiazepin-5-ones, Privileged Scaffolds for Drug Discovery 91
Chemical biology of Histone acetyltransferase natural compounds modulators. 90
Design, synthesis and biological evaluation of new selective arginine methyltransferases (PRMTs) Inhibitors 87
Small Molecule Inhibitors of Histone Arginine Methyltransferases: Homology Modeling, Molecular Docking, Binding Mode Analysis and Biological Evaluations 86
Effects of azole treatments on the physical properties of Candida albicans plasma membrane: A spin probe EPR study 86
Interaction of Azole Compounds with DOPC and DOPC/Ergosterol Bilayers by Spin Probe EPR Spectroscopy: Implications for Antifungal Activity 86
Synthesis of 3-Aryl/benzyl-4,5,6,6a-tetrahydro-3aH-pyrrolo[3,4-d]isoxazole Derivatives: A Comparison between Conventional, Microwave-Assisted and Flow-Based Methodologies. 84
Synthesis and evaluation of new TSPO PET radioligands with low sensitivity to human genotype 84
The Histone Acetylase Activator Pentadecylidenemalonate 1b Rescues Proliferation and Differentiation in Human Cardiac Mesenchymal Cells of Type 2 Diabetic Patients 83
Quinoline-Based p300 Histone Acetyltransferase Inhibitors with Pro-apoptotic Activity in Human Leukemia U937 Cells 83
Identification of Limonol Derivatives as Heat Shock Protein 90 (Hsp90) Inhibitors through a Multidisciplinary Approach 82
Nε-lysine acetylation determines dissociation from GAP junctions and lateralization of connexin 43 in normal and dystrophic heart 81
Antimycobacterial activity of ionic fullerene derivatives. 79
Luminometric sub-nanoliter droplet-to-droplet array (LUMDA) and its application to drug screening by phase I metabolism enzymes 78
Synthesis of 11-aryl-5H-imidazo[2,1-c][1,4]benzodiazepines and their benzodiazepine and A1 adenosine binding activity. 77
P300/CBP Associated Factor Regulates Nitroglycerin-Dependent Arterial Relaxation by N -Lysine Acetylation of Contractile Proteins 77
Modulation of cell differentiation, proliferation, and tumor growth by dihydrobenzyloxopyrimidine non-nucleoside reverse transcriptase inhibitors. 77
Identification of 4-hydroxyquinolines inhibitors of p300/CBP histone acetyltransferases 76
A chemoenzymatic approach to the synthesis of the stereoisomers of a b-adrenergic receptor antagonist. 75
Identification of new inhibitors of PRMTs by a multi-substrate-adduct approach 75
Biomolecular and biophysical approaches to interrogate p300: a platform for drug discovery. 74
N-Pyrrylarylsulfones with High Therapeutic Potential 73
New structural analogues of tubulozole induce apoptosis, [Ca2+]i modifications and cytoskeletal disorganization in glial (GL15) and neuronal-like (PC12) cell lines. 72
Synthesis and Evaluation of Translocator 18 kDa Protein (TSPO) Positron Emission Tomography (PET) Radioligands with Low Binding Sensitivity to Human Single Nucleotide Polymorphism rs6971 72
DESIGN, SYNTHESIS AND BIOLOGICAL EVALUATION OF NOVEL G9A INHIBITORS FROM A SCAFFOLD HOPPING APPROACH 72
Synthesis and Biochemical Evaluation of Δ2-Isoxazoline Derivatives as DNA Methyltransferase 1 Inhibitors 71
Design, synthesis and biological evaluation of novel G9a inhibitors with improved brain permeability from a scaffold hopping approach 71
Design, synthesis and in vitro evaluation of bivalent chemical probes for bromo and extra-terminal domain (BET) proteins 70
A new class of antifungal agents. Synthesis and antimycotic activity of disubstituted N-azolylamines. 69
Synthesis and antimicrobial properties of 3-aryl-1-(1,1'-biphenyl-4-yl)-2-(1H-imidazol-1-yl)propanes as 'carba-analogues' of the N-arylmethyl-N-[(1,1'-biphenyl)-4-ylmethyl])-1H-imidazol-1-amines, a new class of antifungal agents. 69
Novel 3,5-Bis(bromohydroxybenzylidene)piperidin-4-ones as Coactivator-associated Arginine Methyltransferase 1 Inhibitors: Enzyme Selectivity and Cellular Activity. 68
Design, synthesis and biological evaluation of pyrrole derivatives as coactivator associated arginine methyltransferase 1 (CARM1) inhibitors 68
Identification of Long Chain Alkylidenemalonates as Novel Small Molecule Modulators of Histone Acetyltransferases 68
6-Alkylthio-4-[1-(2,6-difluorophenyl)alkyl]-1H-[1,3,5]triazin-2-ones (ADATs): Novel Regulators of Cell Differentiation and Proliferation 67
CYP19 (Aromatase): Exploring the Scaffold Flexibility for Novel Selective Inhibitors. 67
5-Aryl-imidazo[2,1-c][1,4]benzodiazepine derivatives as tricyclic constrained analogues of diazepam and Ro5-4864. Synthesis and binding properties at peripheral and central benzodiazepine receptors. 66
Abstract 11858: Epigenetic Reversion of Metabolic Memory Alterations in Human Cardiac Stromal Cells Isolated from Type-2 Diabetic Patients 66
Identification of new inhibitors of PRMTs by a multi-substrate-adduct approach 66
Discovery of a novel chemotype of histone lysine methyltransferase EHMT1/2 (GLP/G9a) inhibitors: rational design, synthesis, biological evaluation and co-crystal structure 66
The emerging role of lysine methyltransferase SETD8 in human diseases 65
Exploiting the 4-Phenylquinazoline Scaffold for the Development of High Affinity Fluorescent Probes for the Translocator Protein (TSPO) 65
Enhancement of lysine acetylation accelerates wound repair 64
TRANSLOCATOR PROTEIN IMAGING AGENTS; METHODS OF MANUFACTURE, AND METHODS OF USE THEREOF 64
Expanding the quinazoline ring to 3H-benzo[e][1,4]diazepine: development of new and selective G9a inhibitors 64
Synthesis of tricyclic triazepinones related to nevirapine. 62
Histone deacetylase inhibitor activity in royal jelly might facilitate caste switching in bees. 62
Synthesis and pharmacological characterization of new analogs of broxaterol. 59
Identification of new KDM4 inhibitors through a HTS and hit refinement strategy 58
The histone methyltransferase EZH2 as a druggable target in SHH medulloblastoma cancer stem cells 57
Design and Synthesis of Novel [60]Fullerene Derivatives as Potential HIV Aspartic Protease Inhibitors. 56
IDENTIFICATION OF NEW KDM4 INHIBITORS THROUGH A HTS AND HIT REFINEMENT STRATEGY 56
Lysine methyltransferase inhibitors: where we are now. 56
Synthesis and antifungal properties of N-[(1,1'-biphenyl)-4-ylmethyl]-1H-imidazol-1-amine derivatives. 55
A continuous-flow synthesis of 1,4-benzodiazepin-5-ones, privileged scaffolds for drug discovery. 55
Discovery of new chemical probes for the MRG15 chromo domain. 54
Development of a Non-Radioactive, No-Wash Biochemical Assay for High-Throughput Screening of Small Molecule Modulators of PHF20. 51
Identification of novel small-molecule ligands of methyl-lysine binding protein PHF20 51
FROM GARCINOL TO BARBITURIC ACID DERIVATIVES: DEVELOPMENT OF NEW AND SELECTIVE P300 INHIBITORS. 50
Synthesis and biological evaluation of delta2-isoxazoline derivatives as DNA methyltransferase 1 (DNMT1) inhibitors 47
Development of a Microscale Thermophoresis-Based Method for Screening and Characterizing Inhibitors of the Methyl-Lysine Reader Protein MRG15 47
Age-dependent attenuation of spatial memory deficits by the histone acetyltransferase p300/CBP-associated factor (PCAF) in 3xTG Alzheimer's disease mice 46
Discovery of the first-in-class chemical probe for the Spindlin1 methyl-lysine reader domain 44
Use of Microscale Thermophoresis (MST) for Studying binding interactions of PRSet-7/SETD8 with small molecule specific inhibitors EPI-9 and EPI-23. 43
Turning Nonselective Inhibitors of Type I Protein Arginine Methyltransferases into Potent and Selective Inhibitors of Protein Arginine Methyltransferase 4 through a Deconstruction-Reconstruction and Fragment-Growing Approach 43
Essential Principles and Recent Progress in the Development of TSPO PET Ligands for Neuroinflammation Imaging 41
From garcinol to barbituric acid derivatives: development of a novel cell-permeable, selective, and noncompetitive inhibitor of KAT3 histone acetyltransferases. 39
Novel 2-substituted-benzimidazole-6-sulfonamides as carbonic anhydrase inhibitors: synthesis, biological evaluation against isoforms I, II, IX and XII and molecular docking studies 39
Discovery of benzo[d]imidazole-6-sulfonamides as Bromodomain and Extra-Terminal Domain (BET) Inhibitors with Selectivity for the First Bromodomain 33
Reverse transcriptase inhibition potentiates target therapy in BRAF-mutant melanomas: effects on cell proliferation, apoptosis, DNA-damage, ROS induction and mitochondrial membrane depolarization 28
Totale 7.950
Categoria #
all - tutte 28.362
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 28.362


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020291 0 0 0 0 0 0 0 12 71 61 142 5
2020/2021785 5 71 88 4 81 36 79 15 96 6 82 222
2021/2022737 6 5 4 7 23 27 11 30 93 108 107 316
2022/20231.192 117 106 27 159 141 240 12 123 182 5 59 21
2023/2024540 41 67 38 14 39 94 28 40 5 23 24 127
2024/2025818 66 25 31 69 121 171 263 72 0 0 0 0
Totale 8.239