UniSa - IRIS Institutional Research Information System

SBARDELLA, Gianluca
 Distribuzione geografica
Salva come PNG Salva come JPEG
Continente #
AS - Asia 12.071
NA - Nord America 11.446
EU - Europa 4.098
SA - Sud America 893
Continente sconosciuto - Info sul continente non disponibili 521
AF - Africa 118
OC - Oceania 7
Totale 29.154
Salva come PNG Salva come JPEG
Nazione #
US - Stati Uniti d'America 11.246
HK - Hong Kong 7.648
SG - Singapore 1.997
IT - Italia 1.840
CN - Cina 950
BR - Brasile 688
VN - Vietnam 553
UA - Ucraina 487
RU - Federazione Russa 407
DE - Germania 333
TR - Turchia 231
IE - Irlanda 203
FR - Francia 192
KR - Corea 154
FI - Finlandia 149
IN - India 133
SE - Svezia 119
GB - Regno Unito 109
BD - Bangladesh 98
AR - Argentina 76
CA - Canada 69
JP - Giappone 56
MX - Messico 56
PL - Polonia 49
IQ - Iraq 44
NL - Olanda 44
PK - Pakistan 39
ZA - Sudafrica 38
ES - Italia 37
AT - Austria 33
ID - Indonesia 32
EC - Ecuador 30
VE - Venezuela 26
CO - Colombia 25
MA - Marocco 20
UZ - Uzbekistan 20
JM - Giamaica 19
CL - Cile 18
CZ - Repubblica Ceca 16
GR - Grecia 15
IL - Israele 13
SA - Arabia Saudita 13
PH - Filippine 12
CR - Costa Rica 10
DZ - Algeria 10
EU - Europa 10
MY - Malesia 10
TN - Tunisia 10
BO - Bolivia 9
CH - Svizzera 9
JO - Giordania 9
PE - Perù 9
PY - Paraguay 9
AE - Emirati Arabi Uniti 8
AZ - Azerbaigian 8
DO - Repubblica Dominicana 8
AL - Albania 7
EG - Egitto 7
KE - Kenya 7
LB - Libano 7
AU - Australia 6
ET - Etiopia 6
GT - Guatemala 6
HN - Honduras 6
HU - Ungheria 6
LT - Lituania 6
RO - Romania 6
TT - Trinidad e Tobago 6
BG - Bulgaria 5
KZ - Kazakistan 5
NI - Nicaragua 5
TH - Thailandia 5
NP - Nepal 4
PR - Porto Rico 4
PT - Portogallo 4
RS - Serbia 4
GE - Georgia 3
HR - Croazia 3
KH - Cambogia 3
NG - Nigeria 3
OM - Oman 3
PA - Panama 3
UY - Uruguay 3
BA - Bosnia-Erzegovina 2
BB - Barbados 2
BE - Belgio 2
DK - Danimarca 2
GH - Ghana 2
LU - Lussemburgo 2
LY - Libia 2
MN - Mongolia 2
NO - Norvegia 2
PS - Palestinian Territory 2
SN - Senegal 2
SV - El Salvador 2
AO - Angola 1
BH - Bahrain 1
BJ - Benin 1
BS - Bahamas 1
BW - Botswana 1
Totale 28.618
Salva come PNG Salva come JPEG
Città #
Hong Kong 7.631
Ann Arbor 2.189
Singapore 998
Chandler 843
San Jose 780
Houston 723
Dallas 702
Woodbridge 666
Jacksonville 636
Wilmington 627
Milan 573
Princeton 565
Ashburn 487
Salerno 252
Beijing 250
Council Bluffs 210
Dublin 199
Izmir 194
The Dalles 163
Dong Ket 161
Rome 160
Lauterbourg 142
Nanjing 136
Ho Chi Minh City 131
Boardman 122
Andover 120
Santa Clara 108
Munich 106
Hanoi 91
Los Angeles 89
Pellezzano 82
New York 80
Memphis 73
Moscow 63
Mestre 59
São Paulo 59
Figino 57
Columbus 55
Tokyo 55
Fairfield 53
Naples 48
Shenyang 39
Dearborn 37
Warsaw 36
Brooklyn 35
Hebei 35
Frankfurt am Main 33
Changsha 32
Turku 32
Fisciano 31
Orem 31
Montreal 29
Atlanta 28
Chicago 28
Seoul 27
Jiaxing 26
Norwalk 26
Nuremberg 26
Turin 26
Washington 26
Nanchang 25
Redwood City 25
Basingstoke 24
Denver 24
Nocera Superiore 24
Boston 23
Pune 23
Rio de Janeiro 23
Düsseldorf 22
Da Nang 21
Falls Church 21
Philadelphia 21
Tianjin 21
Vienna 21
Belo Horizonte 20
Johannesburg 20
Mexico City 20
Guangzhou 19
Jakarta 19
Phoenix 19
Amsterdam 18
Bologna 18
Chennai 18
San Francisco 18
Tashkent 17
Baghdad 16
Buffalo 16
Ankara 14
Helsinki 14
London 14
San Diego 14
Brasília 13
Haiphong 13
Hải Dương 13
Lahore 13
Seattle 13
Shanghai 13
Athens 12
Charlotte 12
Cambridge 11
Totale 22.046
Salva come PNG Salva come JPEG
Nome #
Design, synthesis and biological evaluation of new selective arginine methyltransferases (PRMTs) Inhibitors 1.249
Two novel SIRT1 activators, SCIC2 and SCIC2.1, enhance SIRT1-mediated effects in stress response and senescence 896
Transition state mimics are valuable mechanistic probes for structural studies with the arginine methyltransferase CARM1 787
ChemInform Abstract: Progress in the Development of Lysine Methyltransferase SETD8 Inhibitors 690
Prodrug Approach to Exploit (S) Alanine as Arginine Mimic Moiety in the Development of Protein Arginine Methyltransferase 4 Inhibitors 533
Combined HAT/EZH2 modulation leads to cancer-selective cell death 466
Synthesis and biological evaluation of delta2-isoxazoline derivatives as DNA methyltransferase 1 (DNMT1) inhibitors 466
Successes and challenges in the development of BD1-selective BET inhibitors: a patent review 443
Synthesis and Evaluation of Translocator 18 kDa Protein (TSPO) Positron Emission Tomography (PET) Radioligands with Low Binding Sensitivity to Human Single Nucleotide Polymorphism rs6971 384
Modulation of the Activity of Histone Acetyltransferases by Long Chain Alkylidene-malonates (LoCAMs) 379
A new facile and expeditious synthesis of N-hydroxy-N'-phenyloctanediamide, a potent inducer of terminal cytodifferentiation 356
3-(1H-Pyrrol-2- and -3-yl)-2-oxazolidinones as Novel Monoamine Oxidase Type A Inhibitors 342
Identification of small molecules inhibitors of GCN5 histone acetyltransferase activity. 325
Identification of novel small-molecule ligands of methyl-lysine binding protein PHF20 302
Identification of Structural Features of 2-Alkylidene-1,3-Dicarbonyl Derivatives that Induce Inhibition and/or Activation of Histone Acetyltransferases KAT3B/p300 and KAT2B/PCAF 271
Developing Spindlin1 small-molecule inhibitors by using protein microarrays 260
Identification of a Protein Arginine Methyltransferase 7 (PRMT7)/Protein Arginine Methyltransferase 9 (PRMT9) Inhibitor 259
A novel cell-permeable, selective and noncompetitive inhibitor of KAT3 histone acetyltransferases from a combined molecular pruning/classical isosterism approach 254
FROM GARCINOL TO BARBITURIC ACID DERIVATIVES: DEVELOPMENT OF NEW AND SELECTIVE P300 INHIBITORS. 242
3-(1H-Pyrrol-1-yl)-2-oxazolidinones as Reversible, Highly Potent, and Selective Inhibitors of Monoamine Oxidase Type A 240
ChemInform Abstract: A Practical, Green, and Selective Approach Toward the Synthesis of Pharmacologically Important Quinone-Containing Heterocyclic Systems Using Alumina-Catalyzed Michael Addition Reaction 238
A continuous-flow synthesis of 1,4-benzodiazepin-5-ones, privileged scaffolds for drug discovery 229
Synthesis and biological evaluation of 3-benzyl-1-methyl- and 1-methyl-3-phenyl-isothioureas as potential inhibitors of iNOS 226
Arginine demethylation of G3BP1 promotes stress granule assembly 226
3,4-Dihydro-2-alkoxy-6-benzyl-oxopyrimidines [DABOs]: Development of a potent class of non-nucleoside reverse transcriptase inhibitors 218
Synthesis and antiviral activity of new 3,4-dihydro-2-alkoxy-6-benzyl-4-oxopyrimidines (DABOs), specific inhibitors of human immunodeficiency virus type 1. 209
CARM1 modulators affect epigenome of stem cells and change morphology of nucleoli 203
The identification of a novel natural activator of p300 Histone acetyltranferase provides new insights into the modulation mechanism of this enzyme 199
Antifungal activity of azole compounds CPA18 and CPA109 against azole-susceptible and -resistant strains of Candida albicans 199
A regioselective approach toward the synthesis of pharmacologically important quinone-containing heterocyclic systems 197
In Quest of Chemical Probes for DNA Methylation Reader Proteins: Nucleoside and Dimer Analogues of 5‐Methylcytosine Interact with MBD2 196
Identification of Small-Molecule Enhancers of Arginine Methylation Catalyzed by Coactivator-Associated Arginine Methyltransferase 1 193
A practical, green and selective approach toward the synthesis of pharmacologically important quinone-containing heterocyclic systems using alumina-catalyzed Michael addition reaction. 188
Small-Molecule Inhibitors of Histone Acetyltransferase Activity: Identification and Biological Properties 187
Design, Synthesis and Biological Evaluation of Carboxy Analogues of Arginine Methyltransferase Inhibitor 1 (AMI-1) 183
Inside Cover: Identification of Structural Features of 2-Alkylidene-1,3-Dicarbonyl Derivatives that Induce Inhibition and/or Activation of Histone Acetyltransferases KAT3B/p300 and KAT2B/PCAF (ChemMedChem 1/2015) 178
Preparation of oxo-​pyrimidine compounds for use in pharmaceutical compositions for the treatment of retroviral infection, particularly HIV infection 177
Agenti antimicotici, antimicobatterici e antiprotozoari 177
DESIGN, SYNTHESIS AND BIOLOGICAL EVALUATION OF NOVEL G9A INHIBITORS FROM A SCAFFOLD HOPPING APPROACH 174
Constrained analogues of procaine as novel small molecule inhibitors of DNA methyltransferase-1. 171
Use of Microscale Thermophoresis (MST) for Studying binding interactions of PRSet-7/SETD8 with small molecule specific inhibitors EPI-9 and EPI-23. 171
A TR-FRET-Based Functional Assay for Screening Activators of CARM1 167
Discovery of a novel chemotype of histone lysine methyltransferase EHMT1/2 (GLP/G9a) inhibitors: rational design, synthesis, biological evaluation and co-crystal structure 166
Preparation of 6-​benzyl-​4-​oxopyrimidines as antiviral agents 165
ChemInform Abstract: Chemical Biology of Histone Acetyltransferase Natural Compounds Modulators 164
Synthesis of 2-Alkylthio-6-benzyl-3,4-dihydro-4-oxopyrimidines (DABOs) as Potent and Selective HIV-1 Inhibitors 164
ChemInform Abstract: A Continuous-Flow Synthesis of 1,4-Benzodiazepin-5-ones, Privileged Scaffolds for Drug Discovery 164
Discovery of benzo[d]imidazole-6-sulfonamides as Bromodomain and Extra-Terminal Domain (BET) Inhibitors with Selectivity for the First Bromodomain 163
Inhibition of Wnt/β-Catenin pathway and Histone acetyltransferase activity by Rimonabant: a therapeutic target for colon cancer 163
Progress in the Development of Lysine Methyltransferase SETD8 Inhibitors 162
Chimica farmaceutica 160
3-(1H-Pyrrol-2-yl)-2-oxazolidinones as Novel Monoamine Oxidase Type A Inhibitors 160
Developing Type II F508del-CFTR correctors with a protective effect against respiratory viruses 159
Structure–Activity Relationship Refinement and Further Assessment of 4-phenylquinazoline-2-carboxamide Translocator Protein (TSPO) Ligands as Antiproliferative Agents in Human Glioblastoma Tumors. 158
Regulation of USP37 Expression by REST-associated G9a-dependent Histone Methylation 156
Epigenetic Multiple Ligands: Mixed Histone/Protein Methyltransferase, Acetyltransferase, and Class III Deacetylase (Sirtuin) Inhibitors 156
Design, synthesis and biological evaluation of novel G9a inhibitors with improved brain permeability from a scaffold hopping approach 156
Biomolecular and biophysical approaches to interrogate p300: a platform for drug discovery. 155
Chemioterapici antiprotozoari 154
5-Alkyl-2-(alkylthio)-6-(2,6-dihalophenylmethyl)-3,4-dihydropyrimidin-4( 3H)-ones: novel potent and selective dihydro-alkoxy-benzyl-oxopyrimidine derivatives. 152
Chemical biology of Histone acetyltransferase natural compounds modulators. 152
Highly efficient synthesis and chemical separation of 5-amino- and 7-amino-4-hydroxy-2-naphthoic acids 151
Straightforward, Metal-free, and Stereoselective Synthesis of 9-Oxo- and 10-Hydroxy-2(E)-decenoic acids, Important Components of Honeybee (Apis mellifera) secretions 150
N-[4-(1,1'-biphenylyl)methyl]-4-(4-thiomorpholinylmethyl) benzenamines, a new class of synthetic antituberculosis agents active against Mycobacterium avium. 149
Design, synthesis and biological evaluation of pyrrole derivatives as coactivator associated arginine methyltransferase 1 (CARM1) inhibitors 149
3-(4-Aroyl-1H-pyrrol-2-yl)-N-hydroxy-2-propenamides, a New Class of Synthetic Histone Deacetylase Inhibitors 148
P300/CBP Associated Factor Regulates Nitroglycerin-Dependent Arterial Relaxation by N -Lysine Acetylation of Contractile Proteins 147
Structure-based design, synthesis, and biological evaluation of conformationally restricted novel 2-alkylthio-6-[1-(2,6-difluorophenyl)alkyl]-3,4-dihydro-5-alkylpyrimidin-4(3H)-ones as non-nucleoside inhibitors of HIV-1 reverse transcriptase 146
Computer-Aided Design, Synthesis, and Anti-HIV-1 Activity in Vitro of 2-Alkylamino-6-[1-(2,6-difluorophenyl)alkyl]-3,4-dihydro-5-alkylpyrimidin-4(3H)- ones as Novel Potent Non-Nucleoside Reverse Transcriptase Inhibitors, Also Active Against the Y181C Variant 145
New 6-nitroquinolones: synthesis and antimicrobial activities 144
Identification of new inhibitors of PRMTs by a multi-substrate-adduct approach 144
5-Alkyl-2-alkylamino-6-(2,6-difluorophenylalkyl)-3,4-dihydro-5-alkylpyrimidin-4(3H)-ones, a New Series of Potent, Broad-Spectrum Non-Nucleoside Reverse Transcriptase Inhibitors Belonging to the DABO family 143
Design, synthesis and in vitro evaluation of bivalent chemical probes for bromo and extra-terminal domain (BET) proteins 143
MECHANISMS OF IMMUNE RESISTANCE IN PEDIATRIC POSTERIOR FOSSA TUMORS 142
6-[1-(2,6-Difluorophenyl)ethyl]pyrimidinones Antagonize Cell Proliferation and Induce Cell Differentiation by Inhibiting (a Non Telomeric) Endogenous Reverse Transcriptase 139
Crystal structure of 3,4-dihydro-6-(3¢-methylbenzyl)-2-[(1-methyl-propyl)thio]-4-oxopyrimidine (S-DABO 618), C16H20N2OS and of 3,4-dihydro-2-[(1-methylpropyl)thio]-6-(2-naphthylmethyl)-4-oxopyrimidine (DATNO 774), C19H20N2OS, two HIV-1 reverse transcriptase inhibitors 139
Nitroquinolones with broad-spectrum antimycobacterial activity in vitro. 138
A continuous-flow synthesis of 1,4-benzodiazepin-5-ones, privileged scaffolds for drug discovery. 138
Modulation of cell differentiation, proliferation, and tumor growth by dihydrobenzyloxopyrimidine non-nucleoside reverse transcriptase inhibitors. 136
Sympathy for the methyl: a library-on-library screening approach to identify small-molecule ligands of methyl-lysine reader proteins 135
Synthesis and biological evaluation of enantiomerically pure pyrrolyl-oxazolidinones as a new class of potent and selective monoamine oxidase type A inhibitors 134
Preparation of substituted 6-​benzyl-​4-​oxopyrimidines for prevention and treatment of HIV infection 134
Synthesis and Biological Evaluation of 4-Phenylquinazoline-2-carboxamides Designed as a Novel Class of Potent Ligands of the Translocator Protein 133
Development of alkyl glycerone phosphate synthase inhibitors: Structure-activity relationship and effects on ether lipids and epithelial-mesenchymal transition in cancer cells 133
Synthesis and Biological Properties of Novel 2-Aminopyrimidin-4(3H)-ones Highly Potent against HIV-1 Mutant Strains 132
Expanding the quinazoline ring to 3H-benzo[e][1,4]diazepine: development of new and selective G9a inhibitors 131
Does the 2-methylthiomethyl substituent really confer high anti-HIV-1 activity to S-DABOs ? 130
STUDY OF EPIGENETIC DEREGULATION OF A NOVEL DEUBIQUITYLASE IN MEDULLOBLASTOMA 130
ChemInform Abstract: A New Facile and Expeditious Synthesis of N-Hydroxy-N′-phenyloctanediamide, a Potent Inducer of Terminal Cytodifferentiation 130
The emerging role of lysine methyltransferase SETD8 in human diseases 129
A transcriptional coregulator, SPIN-DOC, attenuates the coactivator activity of Spindlin1 129
Synthesis and anti-HIV-1 activity of thio analogues of dihydroalkoxybenzyloxopyrimidines. 129
Identification of PR-SET7 and EZH2 selective inhibitors inducing cell death in human leukemia U937 cells 128
Chiral resolution and molecular modeling investigation of rac-2-cyclopentylthio-6-[1-(2,6-difluorophenyl)ethyl]-3,4-dihydro-5- methylpyrimidin-4(3H)-one (MC-1047), a potent anti-HIV-1 reverse transcriptase agent of the DABO class. 128
p300/CBP-Associated Factor Selectively Regulates the Extinction of Conditioned Fear 127
A novel Gcn5p inhibitor represses cell growth, gene transcription and histone acetylation in budding yeast 126
Binding Mode Analysis of 3-(4-Benzoyl-1-methyl-1H-2-pyrrolyl)-N-hydroxy-2-propenamide: A New Synthetic Histone Deacetylase Inhibitor Inducing Histone Hyperacetylation, Growth Inhibition, and Terminal Cell Differentiation 126
Quinoline-Based p300 Histone Acetyltransferase Inhibitors with Pro-apoptotic Activity in Human Leukemia U937 Cells 126
ChemInform Abstract: Nitroquinolones with Broad-Spectrum Antimycobacterial Activity in vitro 126
Identification of new inhibitors of PRMTs by a multi-substrate-adduct approach 126
Totale 21.792
Salva come PNG Salva come JPEG
Categoria #
all - tutte 80.314
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 80.314
Salva come PNG Salva come JPEG


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20221.055 0 6 6 8 26 32 20 45 130 142 164 476
2022/20231.823 173 169 56 261 220 355 16 175 285 8 72 33
2023/2024710 62 108 64 30 42 112 38 23 7 27 38 159
2024/20252.495 94 39 45 132 210 268 377 218 423 128 314 247
2025/202615.015 2.142 3.576 3.140 498 940 471 1.221 332 498 858 352 987
2026/2027575 401 174 0 0 0 0 0 0 0 0 0 0
Totale 29.154