UniSa - IRIS Institutional Research Information System

SBARDELLA, Gianluca
 Distribuzione geografica
Salva come PNG Salva come JPEG
Continente #
AS - Asia 10.434
NA - Nord America 9.325
EU - Europa 2.707
SA - Sud America 668
AF - Africa 62
Continente sconosciuto - Info sul continente non disponibili 10
OC - Oceania 5
Totale 23.211
Salva come PNG Salva come JPEG
Nazione #
US - Stati Uniti d'America 9.243
HK - Hong Kong 7.471
SG - Singapore 1.323
IT - Italia 798
CN - Cina 782
BR - Brasile 583
UA - Ucraina 476
RU - Federazione Russa 397
DE - Germania 293
VN - Vietnam 285
TR - Turchia 215
IE - Irlanda 198
FI - Finlandia 137
KR - Corea 125
SE - Svezia 116
GB - Regno Unito 67
IN - India 63
FR - Francia 42
PL - Polonia 40
AR - Argentina 38
CA - Canada 34
JP - Giappone 33
AT - Austria 30
ES - Italia 27
MX - Messico 26
NL - Olanda 24
ZA - Sudafrica 24
BD - Bangladesh 22
ID - Indonesia 18
IQ - Iraq 17
PK - Pakistan 17
CZ - Repubblica Ceca 16
EC - Ecuador 13
GR - Grecia 13
UZ - Uzbekistan 11
EU - Europa 10
CO - Colombia 9
IL - Israele 8
MA - Marocco 8
VE - Venezuela 8
CL - Cile 7
DO - Repubblica Dominicana 7
PE - Perù 7
DZ - Algeria 6
AE - Emirati Arabi Uniti 5
BG - Bulgaria 5
LB - Libano 5
AU - Australia 4
LT - Lituania 4
RO - Romania 4
TN - Tunisia 4
AZ - Azerbaigian 3
CH - Svizzera 3
EG - Egitto 3
JO - Giordania 3
KE - Kenya 3
KH - Cambogia 3
KZ - Kazakistan 3
NP - Nepal 3
PH - Filippine 3
TT - Trinidad e Tobago 3
BA - Bosnia-Erzegovina 2
CR - Costa Rica 2
DK - Danimarca 2
ET - Etiopia 2
GE - Georgia 2
GT - Guatemala 2
JM - Giamaica 2
MY - Malesia 2
NI - Nicaragua 2
NO - Norvegia 2
PS - Palestinian Territory 2
PT - Portogallo 2
PY - Paraguay 2
RS - Serbia 2
SA - Arabia Saudita 2
SN - Senegal 2
TH - Thailandia 2
AL - Albania 1
BE - Belgio 1
BJ - Benin 1
BS - Bahamas 1
BW - Botswana 1
BZ - Belize 1
CG - Congo 1
CV - Capo Verde 1
DM - Dominica 1
EE - Estonia 1
GH - Ghana 1
GN - Guinea 1
HR - Croazia 1
IR - Iran 1
KW - Kuwait 1
LU - Lussemburgo 1
MD - Moldavia 1
MN - Mongolia 1
MW - Malawi 1
MZ - Mozambico 1
NA - Namibia 1
NG - Nigeria 1
Totale 23.204
Salva come PNG Salva come JPEG
Città #
Hong Kong 7.463
Ann Arbor 2.189
Chandler 842
Houston 717
Dallas 691
Woodbridge 666
Jacksonville 633
Wilmington 627
Princeton 565
Singapore 465
Ashburn 304
Salerno 228
Beijing 194
Izmir 194
Dublin 193
Dong Ket 161
Nanjing 136
Boardman 122
Andover 120
Munich 106
Pellezzano 82
Los Angeles 63
Moscow 61
The Dalles 60
Mestre 59
Columbus 53
Fairfield 53
São Paulo 50
New York 49
Ho Chi Minh City 45
Shenyang 39
Dearborn 37
Hebei 35
Santa Clara 33
Changsha 32
Tokyo 32
Turku 32
Council Bluffs 30
Warsaw 28
Jiaxing 26
Norwalk 26
Seoul 26
Fisciano 25
Nanchang 25
Redwood City 25
Nocera Superiore 24
Naples 23
Düsseldorf 22
Montreal 22
Rome 22
Falls Church 21
Hanoi 21
Pune 21
Tianjin 21
Washington 21
Nuremberg 20
Vienna 20
Brooklyn 19
Denver 19
Belo Horizonte 18
Rio de Janeiro 18
Atlanta 17
Boston 17
Philadelphia 17
Chicago 16
Guangzhou 16
Jakarta 15
Johannesburg 15
Ankara 13
Milan 13
San Diego 13
San Francisco 13
Chennai 12
Phoenix 12
Amsterdam 11
Brasília 11
Cambridge 11
London 11
Athens 10
Napoli 10
Orem 10
Paris 10
Poplar 10
Seattle 10
Brno 9
Hefei 9
Tashkent 9
Campinas 8
Kraków 8
Manchester 8
Mexico City 8
Sarno 8
Shanghai 8
Stockholm 8
Guarulhos 7
Jinan 7
Raleigh 7
Recife 7
Scafati 7
Zhengzhou 7
Totale 18.392
Salva come PNG Salva come JPEG
Nome #
Design, synthesis and biological evaluation of new selective arginine methyltransferases (PRMTs) Inhibitors 1.206
Two novel SIRT1 activators, SCIC2 and SCIC2.1, enhance SIRT1-mediated effects in stress response and senescence 877
Transition state mimics are valuable mechanistic probes for structural studies with the arginine methyltransferase CARM1 755
ChemInform Abstract: Progress in the Development of Lysine Methyltransferase SETD8 Inhibitors 664
Prodrug Approach to Exploit (S) Alanine as Arginine Mimic Moiety in the Development of Protein Arginine Methyltransferase 4 Inhibitors 493
Combined HAT/EZH2 modulation leads to cancer-selective cell death 445
Synthesis and biological evaluation of delta2-isoxazoline derivatives as DNA methyltransferase 1 (DNMT1) inhibitors 430
Successes and challenges in the development of BD1-selective BET inhibitors: a patent review 413
Synthesis and Evaluation of Translocator 18 kDa Protein (TSPO) Positron Emission Tomography (PET) Radioligands with Low Binding Sensitivity to Human Single Nucleotide Polymorphism rs6971 367
Modulation of the Activity of Histone Acetyltransferases by Long Chain Alkylidene-malonates (LoCAMs) 351
3-(1H-Pyrrol-2- and -3-yl)-2-oxazolidinones as Novel Monoamine Oxidase Type A Inhibitors 316
A new facile and expeditious synthesis of N-hydroxy-N'-phenyloctanediamide, a potent inducer of terminal cytodifferentiation 308
Identification of small molecules inhibitors of GCN5 histone acetyltransferase activity. 300
Identification of novel small-molecule ligands of methyl-lysine binding protein PHF20 264
Developing Spindlin1 small-molecule inhibitors by using protein microarrays 241
Identification of Structural Features of 2-Alkylidene-1,3-Dicarbonyl Derivatives that Induce Inhibition and/or Activation of Histone Acetyltransferases KAT3B/p300 and KAT2B/PCAF 238
Identification of a Protein Arginine Methyltransferase 7 (PRMT7)/Protein Arginine Methyltransferase 9 (PRMT9) Inhibitor 218
A novel cell-permeable, selective and noncompetitive inhibitor of KAT3 histone acetyltransferases from a combined molecular pruning/classical isosterism approach 208
FROM GARCINOL TO BARBITURIC ACID DERIVATIVES: DEVELOPMENT OF NEW AND SELECTIVE P300 INHIBITORS. 208
3-(1H-Pyrrol-1-yl)-2-oxazolidinones as Reversible, Highly Potent, and Selective Inhibitors of Monoamine Oxidase Type A 207
Arginine demethylation of G3BP1 promotes stress granule assembly 203
Synthesis and biological evaluation of 3-benzyl-1-methyl- and 1-methyl-3-phenyl-isothioureas as potential inhibitors of iNOS 193
A continuous-flow synthesis of 1,4-benzodiazepin-5-ones, privileged scaffolds for drug discovery 191
Synthesis and antiviral activity of new 3,4-dihydro-2-alkoxy-6-benzyl-4-oxopyrimidines (DABOs), specific inhibitors of human immunodeficiency virus type 1. 185
3,4-Dihydro-2-alkoxy-6-benzyl-oxopyrimidines [DABOs]: Development of a potent class of non-nucleoside reverse transcriptase inhibitors 185
Antifungal activity of azole compounds CPA18 and CPA109 against azole-susceptible and -resistant strains of Candida albicans 178
The identification of a novel natural activator of p300 Histone acetyltranferase provides new insights into the modulation mechanism of this enzyme 170
CARM1 modulators affect epigenome of stem cells and change morphology of nucleoli 168
A regioselective approach toward the synthesis of pharmacologically important quinone-containing heterocyclic systems 167
Identification of Small-Molecule Enhancers of Arginine Methylation Catalyzed by Coactivator-Associated Arginine Methyltransferase 1 159
In Quest of Chemical Probes for DNA Methylation Reader Proteins: Nucleoside and Dimer Analogues of 5‐Methylcytosine Interact with MBD2 157
Preparation of oxo-​pyrimidine compounds for use in pharmaceutical compositions for the treatment of retroviral infection, particularly HIV infection 156
A practical, green and selective approach toward the synthesis of pharmacologically important quinone-containing heterocyclic systems using alumina-catalyzed Michael addition reaction. 151
Small-Molecule Inhibitors of Histone Acetyltransferase Activity: Identification and Biological Properties 150
Agenti antimicotici, antimicobatterici e antiprotozoari 150
Design, Synthesis and Biological Evaluation of Carboxy Analogues of Arginine Methyltransferase Inhibitor 1 (AMI-1) 145
Inside Cover: Identification of Structural Features of 2-Alkylidene-1,3-Dicarbonyl Derivatives that Induce Inhibition and/or Activation of Histone Acetyltransferases KAT3B/p300 and KAT2B/PCAF (ChemMedChem 1/2015) 144
Preparation of 6-​benzyl-​4-​oxopyrimidines as antiviral agents 144
Synthesis of 2-Alkylthio-6-benzyl-3,4-dihydro-4-oxopyrimidines (DABOs) as Potent and Selective HIV-1 Inhibitors 143
A TR-FRET-Based Functional Assay for Screening Activators of CARM1 141
Constrained analogues of procaine as novel small molecule inhibitors of DNA methyltransferase-1. 138
Discovery of a novel chemotype of histone lysine methyltransferase EHMT1/2 (GLP/G9a) inhibitors: rational design, synthesis, biological evaluation and co-crystal structure 138
Use of Microscale Thermophoresis (MST) for Studying binding interactions of PRSet-7/SETD8 with small molecule specific inhibitors EPI-9 and EPI-23. 137
Developing Type II F508del-CFTR correctors with a protective effect against respiratory viruses 134
Chemical biology of Histone acetyltransferase natural compounds modulators. 133
ChemInform Abstract: A Practical, Green, and Selective Approach Toward the Synthesis of Pharmacologically Important Quinone-Containing Heterocyclic Systems Using Alumina-Catalyzed Michael Addition Reaction 132
Regulation of USP37 Expression by REST-associated G9a-dependent Histone Methylation 132
ChemInform Abstract: A Continuous-Flow Synthesis of 1,4-Benzodiazepin-5-ones, Privileged Scaffolds for Drug Discovery 131
Epigenetic Multiple Ligands: Mixed Histone/Protein Methyltransferase, Acetyltransferase, and Class III Deacetylase (Sirtuin) Inhibitors 130
Chemioterapici antiprotozoari 129
Progress in the Development of Lysine Methyltransferase SETD8 Inhibitors 128
Discovery of benzo[d]imidazole-6-sulfonamides as Bromodomain and Extra-Terminal Domain (BET) Inhibitors with Selectivity for the First Bromodomain 127
3-(1H-Pyrrol-2-yl)-2-oxazolidinones as Novel Monoamine Oxidase Type A Inhibitors 127
Straightforward, Metal-free, and Stereoselective Synthesis of 9-Oxo- and 10-Hydroxy-2(E)-decenoic acids, Important Components of Honeybee (Apis mellifera) secretions 126
P300/CBP Associated Factor Regulates Nitroglycerin-Dependent Arterial Relaxation by N -Lysine Acetylation of Contractile Proteins 126
Inhibition of Wnt/β-Catenin pathway and Histone acetyltransferase activity by Rimonabant: a therapeutic target for colon cancer 125
Computer-Aided Design, Synthesis, and Anti-HIV-1 Activity in Vitro of 2-Alkylamino-6-[1-(2,6-difluorophenyl)alkyl]-3,4-dihydro-5-alkylpyrimidin-4(3H)- ones as Novel Potent Non-Nucleoside Reverse Transcriptase Inhibitors, Also Active Against the Y181C Variant 124
5-Alkyl-2-(alkylthio)-6-(2,6-dihalophenylmethyl)-3,4-dihydropyrimidin-4( 3H)-ones: novel potent and selective dihydro-alkoxy-benzyl-oxopyrimidine derivatives. 124
DESIGN, SYNTHESIS AND BIOLOGICAL EVALUATION OF NOVEL G9A INHIBITORS FROM A SCAFFOLD HOPPING APPROACH 123
Crystal structure of 3,4-dihydro-6-(3¢-methylbenzyl)-2-[(1-methyl-propyl)thio]-4-oxopyrimidine (S-DABO 618), C16H20N2OS and of 3,4-dihydro-2-[(1-methylpropyl)thio]-6-(2-naphthylmethyl)-4-oxopyrimidine (DATNO 774), C19H20N2OS, two HIV-1 reverse transcriptase inhibitors 119
N-[4-(1,1'-biphenylyl)methyl]-4-(4-thiomorpholinylmethyl) benzenamines, a new class of synthetic antituberculosis agents active against Mycobacterium avium. 118
3-(4-Aroyl-1H-pyrrol-2-yl)-N-hydroxy-2-propenamides, a New Class of Synthetic Histone Deacetylase Inhibitors 118
MECHANISMS OF IMMUNE RESISTANCE IN PEDIATRIC POSTERIOR FOSSA TUMORS 117
ChemInform Abstract: Chemical Biology of Histone Acetyltransferase Natural Compounds Modulators 116
Preparation of substituted 6-​benzyl-​4-​oxopyrimidines for prevention and treatment of HIV infection 115
Design, synthesis and biological evaluation of pyrrole derivatives as coactivator associated arginine methyltransferase 1 (CARM1) inhibitors 114
5-Alkyl-2-alkylamino-6-(2,6-difluorophenylalkyl)-3,4-dihydro-5-alkylpyrimidin-4(3H)-ones, a New Series of Potent, Broad-Spectrum Non-Nucleoside Reverse Transcriptase Inhibitors Belonging to the DABO family 113
Nitroquinolones with broad-spectrum antimycobacterial activity in vitro. 113
Structure–Activity Relationship Refinement and Further Assessment of 4-phenylquinazoline-2-carboxamide Translocator Protein (TSPO) Ligands as Antiproliferative Agents in Human Glioblastoma Tumors. 113
Biomolecular and biophysical approaches to interrogate p300: a platform for drug discovery. 113
Structure-based design, synthesis, and biological evaluation of conformationally restricted novel 2-alkylthio-6-[1-(2,6-difluorophenyl)alkyl]-3,4-dihydro-5-alkylpyrimidin-4(3H)-ones as non-nucleoside inhibitors of HIV-1 reverse transcriptase 111
New 6-nitroquinolones: synthesis and antimicrobial activities 110
Identification of PR-SET7 and EZH2 selective inhibitors inducing cell death in human leukemia U937 cells 110
Synthesis and biological evaluation of enantiomerically pure pyrrolyl-oxazolidinones as a new class of potent and selective monoamine oxidase type A inhibitors 109
Synthesis and Biological Evaluation of 4-Phenylquinazoline-2-carboxamides Designed as a Novel Class of Potent Ligands of the Translocator Protein 109
Identification of new inhibitors of PRMTs by a multi-substrate-adduct approach 109
Synthesis and Biological Properties of Novel 2-Aminopyrimidin-4(3H)-ones Highly Potent against HIV-1 Mutant Strains 108
p300/CBP-Associated Factor Selectively Regulates the Extinction of Conditioned Fear 108
Sympathy for the methyl: a library-on-library screening approach to identify small-molecule ligands of methyl-lysine reader proteins 108
Design, synthesis and in vitro evaluation of bivalent chemical probes for bromo and extra-terminal domain (BET) proteins 107
Chiral resolution and molecular modeling investigation of rac-2-cyclopentylthio-6-[1-(2,6-difluorophenyl)ethyl]-3,4-dihydro-5- methylpyrimidin-4(3H)-one (MC-1047), a potent anti-HIV-1 reverse transcriptase agent of the DABO class. 107
Cover Picture: A TR-FRET-Based Functional Assay for Screening Activators of CARM1 (ChemBioChem 7/2013) 106
ChemInform Abstract: Nitroquinolones with Broad-Spectrum Antimycobacterial Activity in vitro 106
Design, synthesis and biological evaluation of novel G9a inhibitors with improved brain permeability from a scaffold hopping approach 106
Binding Mode Analysis of 3-(4-Benzoyl-1-methyl-1H-2-pyrrolyl)-N-hydroxy-2-propenamide: A New Synthetic Histone Deacetylase Inhibitor Inducing Histone Hyperacetylation, Growth Inhibition, and Terminal Cell Differentiation 105
ChemInform Abstract: A New Facile and Expeditious Synthesis of N-Hydroxy-N′-phenyloctanediamide, a Potent Inducer of Terminal Cytodifferentiation 105
Arylketotetramethylene analogs of disoxaril with anti-human rhinovirus 14 activity. 104
Modulation of cell differentiation, proliferation, and tumor growth by dihydrobenzyloxopyrimidine non-nucleoside reverse transcriptase inhibitors. 104
6-[1-(2,6-Difluorophenyl)ethyl]pyrimidinones Antagonize Cell Proliferation and Induce Cell Differentiation by Inhibiting (a Non Telomeric) Endogenous Reverse Transcriptase 103
ChemInform Abstract: N-[4-(1,1′-Biphenyl)methyl]-4-(4-thiomorpholinylmethyl)benzenamines as Non-oxazolidinone Analogues of Antimycobacterial U-100480 103
Structure-activity relationship studies on new DABOs: effect of substitutions at pyrimidine C-5 and C-6 positions on anti-HIV-1 activity 102
Synthesis of 3-Aryl/benzyl-4,5,6,6a-tetrahydro-3aH-pyrrolo[3,4-d]isoxazole Derivatives: A Comparison between Conventional, Microwave-Assisted and Flow-Based Methodologies. 102
Highly efficient synthesis and chemical separation of 5-amino- and 7-amino-4-hydroxy-2-naphthoic acids 101
STUDY OF EPIGENETIC DEREGULATION OF A NOVEL DEUBIQUITYLASE IN MEDULLOBLASTOMA 101
Ellagic Acid-Changed Epigenome of Ribosomal Genes and Condensed RPA194-Positive Regions of Nucleoli in Tumour Cells 100
The emerging role of lysine methyltransferase SETD8 in human diseases 100
A novel Gcn5p inhibitor represses cell growth, gene transcription and histone acetylation in budding yeast 99
Quinoline-Based p300 Histone Acetyltransferase Inhibitors with Pro-apoptotic Activity in Human Leukemia U937 Cells 99
Does the 2-methylthiomethyl substituent really confer high anti-HIV-1 activity to S-DABOs ? 98
Development of alkyl glycerone phosphate synthase inhibitors: Structure-activity relationship and effects on ether lipids and epithelial-mesenchymal transition in cancer cells 98
Totale 18.660
Salva come PNG Salva come JPEG
Categoria #
all - tutte 66.131
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 66.131
Salva come PNG Salva come JPEG


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021806 0 0 0 0 119 42 120 25 141 14 126 219
2021/20221.058 3 6 6 8 26 32 20 45 130 142 164 476
2022/20231.823 173 169 56 261 220 355 16 175 285 8 72 33
2023/2024710 62 108 64 30 42 112 38 23 7 27 38 159
2024/20252.495 94 39 45 132 210 268 377 218 423 128 314 247
2025/202610.139 2.142 3.576 3.140 498 783 0 0 0 0 0 0 0
Totale 23.703