UniSa - IRIS Institutional Research Information System

SBARDELLA, Gianluca
 Distribuzione geografica
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Continente #
AS - Asia 11.960
NA - Nord America 11.097
EU - Europa 3.169
SA - Sud America 878
AF - Africa 118
Continente sconosciuto - Info sul continente non disponibili 10
OC - Oceania 7
Totale 27.239
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Nazione #
US - Stati Uniti d'America 10.951
HK - Hong Kong 7.623
SG - Singapore 1.966
IT - Italia 932
CN - Cina 915
BR - Brasile 679
VN - Vietnam 552
UA - Ucraina 487
RU - Federazione Russa 407
DE - Germania 331
TR - Turchia 231
IE - Irlanda 203
FR - Francia 190
KR - Corea 153
FI - Finlandia 149
IN - India 133
SE - Svezia 117
GB - Regno Unito 108
BD - Bangladesh 83
AR - Argentina 76
JP - Giappone 56
MX - Messico 52
PL - Polonia 48
CA - Canada 47
IQ - Iraq 44
NL - Olanda 41
PK - Pakistan 39
ZA - Sudafrica 38
ES - Italia 34
AT - Austria 33
ID - Indonesia 31
EC - Ecuador 26
CO - Colombia 25
VE - Venezuela 25
MA - Marocco 20
UZ - Uzbekistan 20
CL - Cile 18
CZ - Repubblica Ceca 16
GR - Grecia 15
IL - Israele 12
PH - Filippine 12
SA - Arabia Saudita 12
DZ - Algeria 10
EU - Europa 10
MY - Malesia 10
TN - Tunisia 10
BO - Bolivia 9
CH - Svizzera 9
JO - Giordania 9
PY - Paraguay 9
AE - Emirati Arabi Uniti 8
AZ - Azerbaigian 8
DO - Repubblica Dominicana 8
PE - Perù 8
AL - Albania 7
EG - Egitto 7
JM - Giamaica 7
KE - Kenya 7
LB - Libano 7
AU - Australia 6
CR - Costa Rica 6
ET - Etiopia 6
LT - Lituania 6
RO - Romania 6
BG - Bulgaria 5
KZ - Kazakistan 5
TH - Thailandia 5
GT - Guatemala 4
NI - Nicaragua 4
NP - Nepal 4
RS - Serbia 4
TT - Trinidad e Tobago 4
GE - Georgia 3
HN - Honduras 3
HR - Croazia 3
KH - Cambogia 3
NG - Nigeria 3
OM - Oman 3
PA - Panama 3
PT - Portogallo 3
UY - Uruguay 3
BA - Bosnia-Erzegovina 2
BE - Belgio 2
DK - Danimarca 2
GH - Ghana 2
LU - Lussemburgo 2
LY - Libia 2
MN - Mongolia 2
NO - Norvegia 2
PR - Porto Rico 2
PS - Palestinian Territory 2
SN - Senegal 2
AO - Angola 1
BB - Barbados 1
BH - Bahrain 1
BJ - Benin 1
BS - Bahamas 1
BW - Botswana 1
BZ - Belize 1
CG - Congo 1
Totale 27.215
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Città #
Hong Kong 7.606
Ann Arbor 2.189
Singapore 978
Chandler 842
San Jose 779
Houston 719
Dallas 694
Woodbridge 666
Jacksonville 635
Wilmington 627
Princeton 565
Ashburn 472
Salerno 228
Beijing 217
Council Bluffs 200
Dublin 198
Izmir 194
Dong Ket 161
The Dalles 161
Lauterbourg 142
Nanjing 136
Ho Chi Minh City 131
Boardman 122
Andover 120
Munich 106
Hanoi 91
Los Angeles 84
Pellezzano 82
Santa Clara 80
New York 76
Memphis 72
Moscow 63
Mestre 59
São Paulo 59
Tokyo 55
Columbus 53
Fairfield 53
Rome 40
Shenyang 39
Dearborn 37
Hebei 35
Naples 35
Warsaw 35
Changsha 32
Turku 32
Fisciano 31
Frankfurt am Main 31
Orem 30
Brooklyn 29
Atlanta 26
Jiaxing 26
Norwalk 26
Nuremberg 26
Seoul 26
Montreal 25
Nanchang 25
Redwood City 25
Washington 25
Basingstoke 24
Chicago 24
Nocera Superiore 24
Milan 23
Pune 23
Rio de Janeiro 23
Denver 22
Düsseldorf 22
Boston 21
Da Nang 21
Falls Church 21
Tianjin 21
Vienna 21
Belo Horizonte 20
Johannesburg 20
Guangzhou 19
Philadelphia 19
Chennai 18
Jakarta 18
Phoenix 18
Amsterdam 17
Mexico City 17
Tashkent 17
Baghdad 16
Ankara 14
Helsinki 14
San Diego 14
San Francisco 14
Brasília 13
Haiphong 13
Hải Dương 13
Lahore 13
London 13
Athens 12
Buffalo 12
Seattle 12
Shanghai 12
Cambridge 11
Paris 11
Poplar 11
Bologna 10
Hefei 10
Totale 21.062
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Nome #
Design, synthesis and biological evaluation of new selective arginine methyltransferases (PRMTs) Inhibitors 1.242
Two novel SIRT1 activators, SCIC2 and SCIC2.1, enhance SIRT1-mediated effects in stress response and senescence 889
Transition state mimics are valuable mechanistic probes for structural studies with the arginine methyltransferase CARM1 781
ChemInform Abstract: Progress in the Development of Lysine Methyltransferase SETD8 Inhibitors 686
Prodrug Approach to Exploit (S) Alanine as Arginine Mimic Moiety in the Development of Protein Arginine Methyltransferase 4 Inhibitors 525
Combined HAT/EZH2 modulation leads to cancer-selective cell death 465
Synthesis and biological evaluation of delta2-isoxazoline derivatives as DNA methyltransferase 1 (DNMT1) inhibitors 459
Successes and challenges in the development of BD1-selective BET inhibitors: a patent review 435
Synthesis and Evaluation of Translocator 18 kDa Protein (TSPO) Positron Emission Tomography (PET) Radioligands with Low Binding Sensitivity to Human Single Nucleotide Polymorphism rs6971 378
Modulation of the Activity of Histone Acetyltransferases by Long Chain Alkylidene-malonates (LoCAMs) 374
A new facile and expeditious synthesis of N-hydroxy-N'-phenyloctanediamide, a potent inducer of terminal cytodifferentiation 348
3-(1H-Pyrrol-2- and -3-yl)-2-oxazolidinones as Novel Monoamine Oxidase Type A Inhibitors 340
Identification of small molecules inhibitors of GCN5 histone acetyltransferase activity. 318
Identification of novel small-molecule ligands of methyl-lysine binding protein PHF20 293
Identification of Structural Features of 2-Alkylidene-1,3-Dicarbonyl Derivatives that Induce Inhibition and/or Activation of Histone Acetyltransferases KAT3B/p300 and KAT2B/PCAF 262
Developing Spindlin1 small-molecule inhibitors by using protein microarrays 259
Identification of a Protein Arginine Methyltransferase 7 (PRMT7)/Protein Arginine Methyltransferase 9 (PRMT9) Inhibitor 246
A novel cell-permeable, selective and noncompetitive inhibitor of KAT3 histone acetyltransferases from a combined molecular pruning/classical isosterism approach 245
3-(1H-Pyrrol-1-yl)-2-oxazolidinones as Reversible, Highly Potent, and Selective Inhibitors of Monoamine Oxidase Type A 233
FROM GARCINOL TO BARBITURIC ACID DERIVATIVES: DEVELOPMENT OF NEW AND SELECTIVE P300 INHIBITORS. 232
ChemInform Abstract: A Practical, Green, and Selective Approach Toward the Synthesis of Pharmacologically Important Quinone-Containing Heterocyclic Systems Using Alumina-Catalyzed Michael Addition Reaction 229
A continuous-flow synthesis of 1,4-benzodiazepin-5-ones, privileged scaffolds for drug discovery 223
Synthesis and biological evaluation of 3-benzyl-1-methyl- and 1-methyl-3-phenyl-isothioureas as potential inhibitors of iNOS 220
Arginine demethylation of G3BP1 promotes stress granule assembly 220
3,4-Dihydro-2-alkoxy-6-benzyl-oxopyrimidines [DABOs]: Development of a potent class of non-nucleoside reverse transcriptase inhibitors 207
Synthesis and antiviral activity of new 3,4-dihydro-2-alkoxy-6-benzyl-4-oxopyrimidines (DABOs), specific inhibitors of human immunodeficiency virus type 1. 200
Antifungal activity of azole compounds CPA18 and CPA109 against azole-susceptible and -resistant strains of Candida albicans 197
A regioselective approach toward the synthesis of pharmacologically important quinone-containing heterocyclic systems 194
CARM1 modulators affect epigenome of stem cells and change morphology of nucleoli 191
The identification of a novel natural activator of p300 Histone acetyltranferase provides new insights into the modulation mechanism of this enzyme 190
Identification of Small-Molecule Enhancers of Arginine Methylation Catalyzed by Coactivator-Associated Arginine Methyltransferase 1 186
In Quest of Chemical Probes for DNA Methylation Reader Proteins: Nucleoside and Dimer Analogues of 5‐Methylcytosine Interact with MBD2 184
A practical, green and selective approach toward the synthesis of pharmacologically important quinone-containing heterocyclic systems using alumina-catalyzed Michael addition reaction. 180
Small-Molecule Inhibitors of Histone Acetyltransferase Activity: Identification and Biological Properties 179
Design, Synthesis and Biological Evaluation of Carboxy Analogues of Arginine Methyltransferase Inhibitor 1 (AMI-1) 177
Preparation of oxo-​pyrimidine compounds for use in pharmaceutical compositions for the treatment of retroviral infection, particularly HIV infection 176
Agenti antimicotici, antimicobatterici e antiprotozoari 172
Constrained analogues of procaine as novel small molecule inhibitors of DNA methyltransferase-1. 169
Inside Cover: Identification of Structural Features of 2-Alkylidene-1,3-Dicarbonyl Derivatives that Induce Inhibition and/or Activation of Histone Acetyltransferases KAT3B/p300 and KAT2B/PCAF (ChemMedChem 1/2015) 169
Preparation of 6-​benzyl-​4-​oxopyrimidines as antiviral agents 163
Use of Microscale Thermophoresis (MST) for Studying binding interactions of PRSet-7/SETD8 with small molecule specific inhibitors EPI-9 and EPI-23. 163
Discovery of a novel chemotype of histone lysine methyltransferase EHMT1/2 (GLP/G9a) inhibitors: rational design, synthesis, biological evaluation and co-crystal structure 162
A TR-FRET-Based Functional Assay for Screening Activators of CARM1 161
DESIGN, SYNTHESIS AND BIOLOGICAL EVALUATION OF NOVEL G9A INHIBITORS FROM A SCAFFOLD HOPPING APPROACH 159
Developing Type II F508del-CFTR correctors with a protective effect against respiratory viruses 157
ChemInform Abstract: A Continuous-Flow Synthesis of 1,4-Benzodiazepin-5-ones, Privileged Scaffolds for Drug Discovery 157
Synthesis of 2-Alkylthio-6-benzyl-3,4-dihydro-4-oxopyrimidines (DABOs) as Potent and Selective HIV-1 Inhibitors 156
Inhibition of Wnt/β-Catenin pathway and Histone acetyltransferase activity by Rimonabant: a therapeutic target for colon cancer 155
Progress in the Development of Lysine Methyltransferase SETD8 Inhibitors 153
3-(1H-Pyrrol-2-yl)-2-oxazolidinones as Novel Monoamine Oxidase Type A Inhibitors 153
Chemical biology of Histone acetyltransferase natural compounds modulators. 151
Discovery of benzo[d]imidazole-6-sulfonamides as Bromodomain and Extra-Terminal Domain (BET) Inhibitors with Selectivity for the First Bromodomain 150
Regulation of USP37 Expression by REST-associated G9a-dependent Histone Methylation 150
5-Alkyl-2-(alkylthio)-6-(2,6-dihalophenylmethyl)-3,4-dihydropyrimidin-4( 3H)-ones: novel potent and selective dihydro-alkoxy-benzyl-oxopyrimidine derivatives. 149
Structure–Activity Relationship Refinement and Further Assessment of 4-phenylquinazoline-2-carboxamide Translocator Protein (TSPO) Ligands as Antiproliferative Agents in Human Glioblastoma Tumors. 149
Chemioterapici antiprotozoari 148
Design, synthesis and biological evaluation of pyrrole derivatives as coactivator associated arginine methyltransferase 1 (CARM1) inhibitors 147
Chimica farmaceutica 146
ChemInform Abstract: Chemical Biology of Histone Acetyltransferase Natural Compounds Modulators 146
Biomolecular and biophysical approaches to interrogate p300: a platform for drug discovery. 146
3-(4-Aroyl-1H-pyrrol-2-yl)-N-hydroxy-2-propenamides, a New Class of Synthetic Histone Deacetylase Inhibitors 145
Epigenetic Multiple Ligands: Mixed Histone/Protein Methyltransferase, Acetyltransferase, and Class III Deacetylase (Sirtuin) Inhibitors 145
Design, synthesis and biological evaluation of novel G9a inhibitors with improved brain permeability from a scaffold hopping approach 145
Computer-Aided Design, Synthesis, and Anti-HIV-1 Activity in Vitro of 2-Alkylamino-6-[1-(2,6-difluorophenyl)alkyl]-3,4-dihydro-5-alkylpyrimidin-4(3H)- ones as Novel Potent Non-Nucleoside Reverse Transcriptase Inhibitors, Also Active Against the Y181C Variant 143
Straightforward, Metal-free, and Stereoselective Synthesis of 9-Oxo- and 10-Hydroxy-2(E)-decenoic acids, Important Components of Honeybee (Apis mellifera) secretions 143
Design, synthesis and in vitro evaluation of bivalent chemical probes for bromo and extra-terminal domain (BET) proteins 141
N-[4-(1,1'-biphenylyl)methyl]-4-(4-thiomorpholinylmethyl) benzenamines, a new class of synthetic antituberculosis agents active against Mycobacterium avium. 140
P300/CBP Associated Factor Regulates Nitroglycerin-Dependent Arterial Relaxation by N -Lysine Acetylation of Contractile Proteins 140
Identification of new inhibitors of PRMTs by a multi-substrate-adduct approach 138
Crystal structure of 3,4-dihydro-6-(3¢-methylbenzyl)-2-[(1-methyl-propyl)thio]-4-oxopyrimidine (S-DABO 618), C16H20N2OS and of 3,4-dihydro-2-[(1-methylpropyl)thio]-6-(2-naphthylmethyl)-4-oxopyrimidine (DATNO 774), C19H20N2OS, two HIV-1 reverse transcriptase inhibitors 137
5-Alkyl-2-alkylamino-6-(2,6-difluorophenylalkyl)-3,4-dihydro-5-alkylpyrimidin-4(3H)-ones, a New Series of Potent, Broad-Spectrum Non-Nucleoside Reverse Transcriptase Inhibitors Belonging to the DABO family 135
Structure-based design, synthesis, and biological evaluation of conformationally restricted novel 2-alkylthio-6-[1-(2,6-difluorophenyl)alkyl]-3,4-dihydro-5-alkylpyrimidin-4(3H)-ones as non-nucleoside inhibitors of HIV-1 reverse transcriptase 135
MECHANISMS OF IMMUNE RESISTANCE IN PEDIATRIC POSTERIOR FOSSA TUMORS 132
New 6-nitroquinolones: synthesis and antimicrobial activities 131
Preparation of substituted 6-​benzyl-​4-​oxopyrimidines for prevention and treatment of HIV infection 131
Synthesis and Biological Evaluation of 4-Phenylquinazoline-2-carboxamides Designed as a Novel Class of Potent Ligands of the Translocator Protein 130
Nitroquinolones with broad-spectrum antimycobacterial activity in vitro. 129
Identification of PR-SET7 and EZH2 selective inhibitors inducing cell death in human leukemia U937 cells 128
Sympathy for the methyl: a library-on-library screening approach to identify small-molecule ligands of methyl-lysine reader proteins 128
A continuous-flow synthesis of 1,4-benzodiazepin-5-ones, privileged scaffolds for drug discovery. 128
6-[1-(2,6-Difluorophenyl)ethyl]pyrimidinones Antagonize Cell Proliferation and Induce Cell Differentiation by Inhibiting (a Non Telomeric) Endogenous Reverse Transcriptase 127
Synthesis and biological evaluation of enantiomerically pure pyrrolyl-oxazolidinones as a new class of potent and selective monoamine oxidase type A inhibitors 127
STUDY OF EPIGENETIC DEREGULATION OF A NOVEL DEUBIQUITYLASE IN MEDULLOBLASTOMA 127
Expanding the quinazoline ring to 3H-benzo[e][1,4]diazepine: development of new and selective G9a inhibitors 127
Modulation of cell differentiation, proliferation, and tumor growth by dihydrobenzyloxopyrimidine non-nucleoside reverse transcriptase inhibitors. 127
Development of alkyl glycerone phosphate synthase inhibitors: Structure-activity relationship and effects on ether lipids and epithelial-mesenchymal transition in cancer cells 126
Chiral resolution and molecular modeling investigation of rac-2-cyclopentylthio-6-[1-(2,6-difluorophenyl)ethyl]-3,4-dihydro-5- methylpyrimidin-4(3H)-one (MC-1047), a potent anti-HIV-1 reverse transcriptase agent of the DABO class. 125
Synthesis and Biological Properties of Novel 2-Aminopyrimidin-4(3H)-ones Highly Potent against HIV-1 Mutant Strains 124
p300/CBP-Associated Factor Selectively Regulates the Extinction of Conditioned Fear 124
Identification of new inhibitors of PRMTs by a multi-substrate-adduct approach 123
Identification of new KDM4 inhibitors through a HTS and hit refinement strategy 123
ChemInform Abstract: A New Facile and Expeditious Synthesis of N-Hydroxy-N′-phenyloctanediamide, a Potent Inducer of Terminal Cytodifferentiation 122
The emerging role of lysine methyltransferase SETD8 in human diseases 121
ChemInform Abstract: N-[4-(1,1′-Biphenyl)methyl]-4-(4-thiomorpholinylmethyl)benzenamines as Non-oxazolidinone Analogues of Antimycobacterial U-100480 120
Turning Nonselective Inhibitors of Type I Protein Arginine Methyltransferases into Potent and Selective Inhibitors of Protein Arginine Methyltransferase 4 through a Deconstruction-Reconstruction and Fragment-Growing Approach 120
A novel Gcn5p inhibitor represses cell growth, gene transcription and histone acetylation in budding yeast 119
Highly efficient synthesis and chemical separation of 5-amino- and 7-amino-4-hydroxy-2-naphthoic acids 119
Binding Mode Analysis of 3-(4-Benzoyl-1-methyl-1H-2-pyrrolyl)-N-hydroxy-2-propenamide: A New Synthetic Histone Deacetylase Inhibitor Inducing Histone Hyperacetylation, Growth Inhibition, and Terminal Cell Differentiation 119
Arylketotetramethylene analogs of disoxaril with anti-human rhinovirus 14 activity. 119
Does the 2-methylthiomethyl substituent really confer high anti-HIV-1 activity to S-DABOs ? 118
Totale 21.075
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Categoria #
all - tutte 75.644
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 75.644
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021219 0 0 0 0 0 0 0 0 0 0 0 219
2021/20221.058 3 6 6 8 26 32 20 45 130 142 164 476
2022/20231.823 173 169 56 261 220 355 16 175 285 8 72 33
2023/2024710 62 108 64 30 42 112 38 23 7 27 38 159
2024/20252.495 94 39 45 132 210 268 377 218 423 128 314 247
2025/202614.183 2.142 3.576 3.140 498 940 471 1.221 332 498 858 352 155
Totale 27.747