BRUNO, Ines
 Distribuzione geografica
Continente #
AS - Asia 7.824
NA - Nord America 5.979
EU - Europa 1.843
SA - Sud America 373
AF - Africa 49
Continente sconosciuto - Info sul continente non disponibili 6
OC - Oceania 4
Totale 16.078
Nazione #
US - Stati Uniti d'America 5.870
HK - Hong Kong 5.620
SG - Singapore 957
CN - Cina 541
IT - Italia 470
UA - Ucraina 310
VN - Vietnam 276
BR - Brasile 275
DE - Germania 249
RU - Federazione Russa 228
IE - Irlanda 111
SE - Svezia 101
TR - Turchia 95
FR - Francia 93
FI - Finlandia 88
GB - Regno Unito 76
IN - India 71
CA - Canada 63
KR - Corea 60
AR - Argentina 37
JP - Giappone 34
BD - Bangladesh 33
MX - Messico 31
IQ - Iraq 26
NL - Olanda 22
CZ - Repubblica Ceca 17
ID - Indonesia 17
AT - Austria 16
CO - Colombia 15
PL - Polonia 15
UZ - Uzbekistan 14
ES - Italia 13
ZA - Sudafrica 13
EC - Ecuador 12
PH - Filippine 11
PK - Pakistan 10
VE - Venezuela 9
CL - Cile 8
SA - Arabia Saudita 7
AZ - Azerbaigian 6
CH - Svizzera 6
HU - Ungheria 6
KE - Kenya 6
PE - Perù 6
AE - Emirati Arabi Uniti 5
EG - Egitto 5
EU - Europa 5
MA - Marocco 5
NP - Nepal 5
OM - Oman 5
BG - Bulgaria 4
BO - Bolivia 4
JO - Giordania 4
LB - Libano 4
MY - Malesia 4
NG - Nigeria 4
TN - Tunisia 4
AU - Australia 3
DZ - Algeria 3
GT - Guatemala 3
IL - Israele 3
KZ - Kazakistan 3
LT - Lituania 3
PY - Paraguay 3
RO - Romania 3
TH - Thailandia 3
TJ - Tagikistan 3
AL - Albania 2
AO - Angola 2
DO - Repubblica Dominicana 2
ET - Etiopia 2
JM - Giamaica 2
NI - Nicaragua 2
PA - Panama 2
PS - Palestinian Territory 2
PT - Portogallo 2
RS - Serbia 2
SK - Slovacchia (Repubblica Slovacca) 2
UY - Uruguay 2
A2 - ???statistics.table.value.countryCode.A2??? 1
BE - Belgio 1
BH - Bahrain 1
CM - Camerun 1
CR - Costa Rica 1
GA - Gabon 1
GF - Guiana Francese 1
GY - Guiana 1
HN - Honduras 1
LA - Repubblica Popolare Democratica del Laos 1
LC - Santa Lucia 1
LU - Lussemburgo 1
MK - Macedonia 1
ML - Mali 1
MN - Mongolia 1
MU - Mauritius 1
NO - Norvegia 1
NZ - Nuova Zelanda 1
PR - Porto Rico 1
QA - Qatar 1
SC - Seychelles 1
Totale 16.077
Città #
Hong Kong 5.611
Ann Arbor 1.074
Singapore 535
Woodbridge 439
Chandler 429
San Jose 427
Houston 392
Jacksonville 372
Dallas 328
Wilmington 325
Princeton 289
Ashburn 278
Beijing 112
Dublin 102
Salerno 101
Council Bluffs 98
The Dalles 98
Lauterbourg 83
Izmir 81
Nanjing 79
Munich 70
Andover 67
Dearborn 67
Ho Chi Minh City 67
Dong Ket 66
Boardman 64
New York 56
Pellezzano 54
Hanoi 50
Los Angeles 43
Naples 36
Montreal 35
Moscow 35
Tokyo 34
Orem 32
Santa Clara 32
Fairfield 30
Mestre 27
Shenyang 26
São Paulo 26
Düsseldorf 25
Redwood City 25
Fisciano 24
Guangzhou 23
Frankfurt am Main 22
Turku 22
Jiaxing 21
Memphis 21
Hebei 20
Brooklyn 19
Denver 19
Changsha 18
Stockholm 18
London 17
Chicago 16
Boston 15
Chennai 15
Columbus 15
Nanchang 15
Warsaw 15
Brno 14
Norwalk 14
Nuremberg 14
Washington 14
Acerra 13
Da Nang 13
Mexico City 13
San Francisco 13
Spinea 13
Phoenix 12
Pune 12
Seattle 12
Tashkent 12
Amsterdam 11
Johannesburg 11
Atlanta 10
Charlotte 10
Tianjin 10
Baghdad 9
Jinan 9
Manchester 9
New Delhi 9
Belo Horizonte 8
Curitiba 8
Rome 8
Dhaka 7
Galway 7
Hải Dương 7
Porto Alegre 7
Ankara 6
Jakarta 6
Medellín 6
Shanghai 6
Wuhan 6
Baku 5
Biên Hòa 5
City of London 5
Des Moines 5
Haiphong 5
Indiana 5
Totale 12.924
Nome #
A Combinatorial Virtual Screening Approach Driving the Synthesis of 2,4-Thiazolidinedione-Based Molecules as New Dual mPGES-1/5-LO Inhibitors 1.128
Inhibition of Microsomal Prostaglandin E2 Synthase 1: focused design of new anti-inflammatory and anti-cancer drugs 942
Identification of 2-(thiophen-2-yl)acetic Acid-Based Lead Compound for mPGES-1 Inhibition 643
Bioactive Prenylhydroquinone Sulfates and a Novel C31 Furanoterpene Alcohol Sulfate from the Marine Sponge, Ircinia Sp. 622
40 th "A. Corbella" International Summer School on Organic Synthesis - ISOS 2015 596
Design, Synthesis, and Biological Activity of Hydroxamic Tertiary Amines as Histone Deacetylase Inhibitors 536
In Silico Design, Chemical Synthesis, Biophysical and in Vitro Evaluation for the Identification of 1-Ethyl-1H-Pyrazolo[3,4-b]Pyridine-Based BRD9 Binders 522
Identification of Novel Bromodomain-Containing Protein 4 (BRD4) Binders through 3D Pharmacophore-Based Repositioning Screening Campaign 401
Identification of the 2-Benzoxazol-2-yl-phenol Scaffold as New Hit for JMJD3 Inhibition 364
9H-purine scaffold reveals induced-fit pocket plasticity of the BRD9 bromodomain 252
Cyclic Peptoids as Mycotoxin Mimics: An Exploration of Their Structural and Biological Properties 206
From Natural Compounds to Bioactive Molecules through NMR and In Silico Methodologies 202
Starfish Saponins, Part 50. Steroidal Glycosides from the Okinawan Starfish Nardoa tuberculata 190
Targeting the Hsp90 C-terminal domain by the chemically accessible dihydropyrimidinone scaffold 189
Structural basis for the design and synthesis of selective HDAC inhibitors 188
Exploration of the dihydropyrimidine scaffold for the development of new potential anti-inflammatory agents blocking prostaglandin E2 synthase-1 enzyme (mPGES-1) 185
Structural Insights for the Optimization of Dihydropyrimidin-2(1H)-one Based mPGES-1 Inhibitors 184
(±)-Gelliusines A and B, Two Diastereomeric Brominated Tris-indole Alkaloids from a Deep Water New Caledonian Marine Sponge (Gellius or Orina sp.) 183
Synthesis, Conformational Analysis, and Cytotoxicity of New Analogues of the Natural Cyclodepsipeptide Jaspamide 172
Design and synthesis of a second series of triazole-based compounds as potent dual mPGES-1 and 5-lipoxygenase inhibitors 171
Biologically active guanidine alkaloids from the Mediterranean sponge Crambe crambe 170
Identification of the key structural elements of a dihydropyrimidinone core driving toward more potent Hsp90 C-terminal inhibitors 170
Makaluvamine P: a New Cytotoxic Pyrroloiminoquinone from Zyzzya cf. fuliginosa 168
Anti-inflammatory and analgesic activity of a novel inhibitor of microsomal prostaglandin E synthase-1 expression 166
Dimeric and trimeric triazole based molecules as a new class of Hsp90 molecular chaperone inhibitors 166
Bioactive Macrolides and Cylopeptides from South Pacific Sponges 166
Design and Synthesis of cyclopeptide analogues of the potent Histone deacetylase inhibitor FR235222 163
Correction: Identification of the key structural elements of a dihydropyrimidinone core driving toward more potent Hsp90 C-terminal inhibitors 161
New dihydropyrimidin-2(1H)-one based Hsp90 C-terminal inhibitors 159
Crambines C1 and C2: two further ichthyotoxic guanidine alkaloids from the sponge Crambe crambe 156
Design,virtual Screening and Synthesis of Potential Microsomal Prostaglandine E2 Synthase-1 (mPGES-1)Inhibitors 155
Identification of 2,4,5-trisubstituted-2,4-dihydro-3H-1,2,4-triazol-3-one-based small molecules as selective BRD9 binders 150
Elucidating new structural features of the triazole scaffold for the development of mPGES-1 inhibitors 145
Targeting Microsomal Prostaglanding E2 Synthase 1 for the Development of new potential Anti-Inflammatory Drugs 143
Discovery of new potent molecular entities able to inhibit mPGES-1 143
Isolation and structure of new polyhydroxylated sterols from a deep-water starfish of the genus Rosaster 142
Identification of Honokiol-Based Scaffold to Design Tankyrase 1/2 Inhibitors by In Silico and In Vitro Studies 141
STARFISH SAPONINS .38. STEROIDAL GLYCOSIDES FROM THE STARFISH PYCNOPODIA-HELIANTHOIDES 141
Effects of FR235222, a novel HDAC inhibitor, in proliferation and apoptosis of human leukaemia cell lines: role of annexin A1 141
Discovery and synthesis of the first selective BAG domain modulator of BAG3 as an attractive candidate for the development of a new class of chemotherapeutics 135
Starfish saponins, part 43. Structures of two new sulfated steroidal fucofuranosides (imbricatosides A and B) and six new polyhydroxysteroids from the starfish Dermasterias imbricata 132
Total Synthesis, NMR Solution Structure, and Binding Model of the Potent Histone Deacetylase Inhibitor FR235222 127
Structure-Based Design of Microsomal Prostaglandin E2 Synthase-1 (mPGES-1) Inhibitors using a Virtual Fragment Growing Optimization Scheme 127
Novel HIV-Inhibitory Halistanol Sulfates F-H from a Marine Sponge, Pseudoaxinissa digitata 126
Dactylolide, a New Cytotoxic Macrolide from the Vanuatu Sponge Dactylospongia sp. 124
Critical Surveys Covering the Year 2004:Total Synthesis of Natural Products 123
Synthesis of new mono and bis amides projected as potential histone deacetylase (HDAC) inhibitors 123
Discovery of new molecular entities able to strongly interfere with Hsp90 C-terminal domain 123
Synthetic approach to bioactive marine Cyclopeptide Halipeptin A 121
Edwardsolides A, B and C. New Sesquiterpenoid Lactones from the Mediterranean OctocoralMaasella edwardsi 120
New Bisindole Alkaloids of the Topsentin and Hamacanthin classes from the Mediterranean marine sponge Rhaphisia lacazei. 120
Molecular modeling studies toward the structural optimization of new cyclopeptide-based HDAC inhibitors modeled on the natural product FR235222 119
Polycyclic guanidine alkaloids from the marine sponge Crambe crambe and calcium channel blocker activity of crambescidin 816 119
Development of a second generation of inhibitors of microsomal prostaglandin E synthase 1 expression bearing the gamma-hydroxybutenolide scaffold 118
Further brominated bis- and tris-indole alkaloids from the deep water New Caledonian marine sponge Orina sp. 116
A multidisciplinary functional proteomics-aided strategy as a tool for the profiling of a novel cytotoxic thiadiazolopyrimidone 116
Toward the Discovery of New Agents Able to Inhibit the Expression of Microsomal Prostaglandin E Synthase-1 Enzyme as Promising Tools in Drug Development 115
Two new guanidine alkaloids from the Mediterranean sponge Crambe crambe 115
Synthetic and pharmacological studies on new simplified analogues of the potent actin-targeting Jaspamide 114
Synthesis, structural aspects and cytotoxicity of the natural cyclopeptides yunnanins A, C and phakellistatins 1, 10 113
Identification by Inverse Virtual Screening of magnolol-based scaffold as new tankyrase-2 inhibitors 113
Structure-Based Discovery of Inhibitors of Microsomal Prostaglandin E2 Synthase-1, 5-Lipoxygenase and 5-Lipoxygenase-Activating Protein: Promising Hits for the Development of New Anti-inflammatory Agents 112
Chemistry and Biology of Chromatin Remodeling Agents: State of Art and Future Perspectives of HDAC Inhibitors 112
Synthesis of 2-Amino-8-oxodecanoic Acids (Aodas) Present in Natural Histone Deacetylase Inhibitors. 110
Synthesis and Pharmacological Evaluation of a Selected Library of New Potential Anti-Inflammatory Agents Bearing the gamma-hydroxybutenolide Scaffold: a New Class of Inhibitors of Prostanoid Production Through the Selective Modulation of Microsomal prostaglandin E Synthase-1 Expression (mPGES-1). 110
Glucopyranosylbianthrones from the Algerian Asphodelus tenuifolius: Structural Insights and Biological Evaluation on Melanoma Cancer Cells 109
Identification of the first-in-class dual inhibitor targeting BAG3 and HSP70 proteins to disrupt multiple chaperone pathways 105
Synthesis and biological activity of cyclotetrapeptide analogues of the natural HDAC inhibitor FR235222 104
Discovery of noscapine derivatives as potential β-tubulin inhibitors 104
Marine eicosanoids: occurrence of 8,11,12-trihydroxylated eicosanoic acids in starfishes 103
Structural Refinement of 2,4-Thiazolidinedione Derivatives as New Anticancer Agents Able to Modulate the BAG3 Protein 102
Dragmacidin F: a New Antiviral Bromo-indole Alkaloid from the Mediterranean Sponge Halicortex sp. 100
Isolation and NMR characterization of rosacelose, a novel sulfated polysaccharide from the sponge Mixylla rosacea. 95
Repositioning of Quinazolinedione-Based Compounds on Soluble Epoxide Hydrolase (sEH) through 3D Structure-Based Pharmacophore Model-Driven Investigation 94
Exploring the chemical space of functionalized [1,2,4]triazolo[4,3-a]quinoxaline-based compounds targeting the bromodomain of BRD9 93
Synthesis, structure, and biological aspects of cyclopeptides related to marine phakellistatins 7-9 92
Identification of new γ-hydroxybutenolides that preferentially inhibit the activity of mPGES-1 91
Tossine marine: nuove affascinanti molecole bioattive da invertebrati e microrganismi marini. Recenti acquisizioni e prospettive 90
Starfish saponins. Part 14. Structures of the steroidal glycoside sufates from the starfish Marthasterias glacialis 88
Synthesis, structural aspects and bioactivity of the marine cyclopeptide hymenamide C. 86
Synthesis, structural aspects and bioactivity of the marine cyclopeptide hymenamide C. 86
Introducing structure-based three-dimensional pharmacophore models for accelerating the discovery of selective BRD9 binders 85
Tuning the biomimetic performances of 4-hydroxyproline-containing cyclic peptoids 82
Synthesis, solution structure, and bioactivity of six new simplified analogues of the natural cyclodepsipeptide jaspamide 81
Synthesis And Biological Properties Of The Seven Alanine-Modified Analogues Of The Marine Cyclopeptide Hymenamide C 78
Targeting mPGES-1 by a Combinatorial Approach: Identification of the Aminobenzothiazole Scaffold to Suppress PGE2Levels 76
Spongidepsin, a new cytotoxic macrolide from Spongia sp. 74
Regioselective Entry to Bromo-γ -hydroxybutenolides: Useful Building Blocks for Assemblying Natural Product-Like Libraries. 71
Identification of 2,4-Dinitro-Biphenyl-Based Compounds as MAPEG Inhibitors 69
Identification of a New Promising BAG3 Modulator Featuring the Imidazopyridine Scaffold 66
Identification of 2-Aminoacyl-1,3,4-thiadiazoles as Prostaglandin E2 and Leukotriene Biosynthesis Inhibitors 45
A Thiadiazolopyrimidinone-Based Molecule Targeting Annexin A6 Impairs Cell Motility and Epithelial-to-Mesenchymal Transition in Pancreatic Cancer Cells Lacking Annexin A1 20
Identification of a New Interesting BAG3 Modulator Able to Disrupt Cancer-Related Pathways 16
Carnosol modulates mPGES-1/PPAR-γ biological axis: from in silico to in vivo clinical imaging and investigations 11
Unveiling New Triazoloquinoxaline‐Based PROTACs Designed for the Selective Degradation of the ncBAF Chromatin Remodeling Subunit BRD9 11
Disruption of c-Myc/Max heterodimerization induced by a novel anticancer agent endowed with 1,3-diphenylurea moiety: an in silico, chemoproteomics-based, and in vitro combined approach 11
From Bench to Bedside: Translational Approaches to Cardiotoxicity in Breast Cancer, Lung Cancer, and Lymphoma Therapies 4
Totale 16.267
Categoria #
all - tutte 43.835
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 43.835


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/202190 0 0 0 0 0 0 0 0 0 0 0 90
2021/2022528 4 0 0 14 13 14 12 14 81 68 68 240
2022/20231.000 90 92 22 143 121 192 6 105 131 0 64 34
2023/2024392 37 59 26 16 48 75 19 19 6 15 12 60
2024/20251.172 47 9 7 59 29 112 239 98 184 52 146 190
2025/20269.065 1.690 2.407 2.174 313 510 229 645 139 290 499 144 25
Totale 16.267