BRUNO, Ines
 Distribuzione geografica
Continente #
AS - Asia 7.006
NA - Nord America 5.018
EU - Europa 1.616
SA - Sud America 262
AF - Africa 20
Continente sconosciuto - Info sul continente non disponibili 6
OC - Oceania 4
Totale 13.932
Nazione #
HK - Hong Kong 5.598
US - Stati Uniti d'America 4.946
SG - Singapore 574
CN - Cina 456
IT - Italia 433
UA - Ucraina 306
RU - Federazione Russa 224
BR - Brasile 223
DE - Germania 223
VN - Vietnam 122
IE - Irlanda 110
SE - Svezia 94
TR - Turchia 88
FI - Finlandia 85
GB - Regno Unito 53
KR - Corea 51
CA - Canada 48
IN - India 33
JP - Giappone 25
MX - Messico 19
CZ - Repubblica Ceca 16
NL - Olanda 16
AR - Argentina 14
AT - Austria 12
ID - Indonesia 11
PL - Polonia 11
BD - Bangladesh 10
ES - Italia 9
UZ - Uzbekistan 8
ZA - Sudafrica 8
IQ - Iraq 7
CO - Colombia 5
EU - Europa 5
AZ - Azerbaigian 4
BG - Bulgaria 4
EC - Ecuador 4
FR - Francia 4
PE - Perù 4
PK - Pakistan 4
VE - Venezuela 4
AE - Emirati Arabi Uniti 3
AU - Australia 3
CH - Svizzera 3
EG - Egitto 3
GT - Guatemala 3
IL - Israele 3
LT - Lituania 3
NG - Nigeria 3
PY - Paraguay 3
DZ - Algeria 2
MA - Marocco 2
RO - Romania 2
RS - Serbia 2
SK - Slovacchia (Repubblica Slovacca) 2
TH - Thailandia 2
TJ - Tagikistan 2
UY - Uruguay 2
A2 - ???statistics.table.value.countryCode.A2??? 1
CL - Cile 1
GF - Guiana Francese 1
GY - Guiana 1
HU - Ungheria 1
KE - Kenya 1
KZ - Kazakistan 1
LC - Santa Lucia 1
LU - Lussemburgo 1
MK - Macedonia 1
MY - Malesia 1
NP - Nepal 1
NZ - Nuova Zelanda 1
PH - Filippine 1
PR - Porto Rico 1
PS - Palestinian Territory 1
PT - Portogallo 1
SC - Seychelles 1
Totale 13.932
Città #
Hong Kong 5.589
Ann Arbor 1.074
Woodbridge 439
Chandler 429
Houston 390
Jacksonville 372
Dallas 325
Wilmington 324
Princeton 289
Singapore 214
Ashburn 185
Dublin 101
Salerno 101
Beijing 91
Izmir 81
Nanjing 78
Munich 70
Andover 67
Dearborn 67
Dong Ket 66
Boardman 64
Pellezzano 54
New York 39
Moscow 35
Los Angeles 32
Fairfield 30
Mestre 27
Düsseldorf 25
Montreal 25
Redwood City 25
Shenyang 25
Tokyo 25
Guangzhou 23
Turku 22
Fisciano 21
Jiaxing 21
São Paulo 21
Hebei 20
Naples 20
Changsha 17
The Dalles 17
Brooklyn 16
Ho Chi Minh City 16
Columbus 15
Nanchang 15
Boston 14
Brno 14
Norwalk 14
Acerra 13
Hanoi 13
Nuremberg 13
San Francisco 13
Spinea 13
Washington 13
Chicago 12
Denver 12
Pune 12
Seattle 12
London 11
Orem 11
Santa Clara 11
Stockholm 11
Warsaw 11
Tianjin 10
Atlanta 9
Jinan 9
Phoenix 9
Charlotte 8
Johannesburg 8
Mexico City 8
Chennai 7
Curitiba 7
Galway 7
Manchester 7
Porto Alegre 7
Rome 7
Tashkent 7
Belo Horizonte 6
Amsterdam 5
Ankara 5
Indiana 5
Jakarta 5
Nürnberg 5
Ottawa 5
Arzano 4
Baghdad 4
Caianello 4
Council Bluffs 4
Des Moines 4
Edinburgh 4
Hải Dương 4
New Delhi 4
Nocera Superiore 4
Pignola 4
Pozzuoli 4
Querétaro 4
Raleigh 4
Tappahannock 4
Vienna 4
Wuhan 4
Totale 11.435
Nome #
A Combinatorial Virtual Screening Approach Driving the Synthesis of 2,4-Thiazolidinedione-Based Molecules as New Dual mPGES-1/5-LO Inhibitors 1.102
Inhibition of Microsomal Prostaglandin E2 Synthase 1: focused design of new anti-inflammatory and anti-cancer drugs 915
Identification of 2-(thiophen-2-yl)acetic Acid-Based Lead Compound for mPGES-1 Inhibition 612
Bioactive Prenylhydroquinone Sulfates and a Novel C31 Furanoterpene Alcohol Sulfate from the Marine Sponge, Ircinia Sp. 597
40 th "A. Corbella" International Summer School on Organic Synthesis - ISOS 2015 564
Design, Synthesis, and Biological Activity of Hydroxamic Tertiary Amines as Histone Deacetylase Inhibitors 506
In Silico Design, Chemical Synthesis, Biophysical and in Vitro Evaluation for the Identification of 1-Ethyl-1H-Pyrazolo[3,4-b]Pyridine-Based BRD9 Binders 500
Identification of Novel Bromodomain-Containing Protein 4 (BRD4) Binders through 3D Pharmacophore-Based Repositioning Screening Campaign 374
Identification of the 2-Benzoxazol-2-yl-phenol Scaffold as New Hit for JMJD3 Inhibition 344
9H-purine scaffold reveals induced-fit pocket plasticity of the BRD9 bromodomain 226
Cyclic Peptoids as Mycotoxin Mimics: An Exploration of Their Structural and Biological Properties 180
From Natural Compounds to Bioactive Molecules through NMR and In Silico Methodologies 177
Starfish Saponins, Part 50. Steroidal Glycosides from the Okinawan Starfish Nardoa tuberculata 171
Structural Insights for the Optimization of Dihydropyrimidin-2(1H)-one Based mPGES-1 Inhibitors 165
Targeting the Hsp90 C-terminal domain by the chemically accessible dihydropyrimidinone scaffold 165
Structural basis for the design and synthesis of selective HDAC inhibitors 163
Exploration of the dihydropyrimidine scaffold for the development of new potential anti-inflammatory agents blocking prostaglandin E2 synthase-1 enzyme (mPGES-1) 158
(±)-Gelliusines A and B, Two Diastereomeric Brominated Tris-indole Alkaloids from a Deep Water New Caledonian Marine Sponge (Gellius or Orina sp.) 156
Makaluvamine P: a New Cytotoxic Pyrroloiminoquinone from Zyzzya cf. fuliginosa 148
Dimeric and trimeric triazole based molecules as a new class of Hsp90 molecular chaperone inhibitors 148
Biologically active guanidine alkaloids from the Mediterranean sponge Crambe crambe 146
Design and synthesis of a second series of triazole-based compounds as potent dual mPGES-1 and 5-lipoxygenase inhibitors 144
Anti-inflammatory and analgesic activity of a novel inhibitor of microsomal prostaglandin E synthase-1 expression 142
Identification of the key structural elements of a dihydropyrimidinone core driving toward more potent Hsp90 C-terminal inhibitors 142
New dihydropyrimidin-2(1H)-one based Hsp90 C-terminal inhibitors 140
Bioactive Macrolides and Cylopeptides from South Pacific Sponges 136
Design and Synthesis of cyclopeptide analogues of the potent Histone deacetylase inhibitor FR235222 133
Correction: Identification of the key structural elements of a dihydropyrimidinone core driving toward more potent Hsp90 C-terminal inhibitors 133
Synthesis, Conformational Analysis, and Cytotoxicity of New Analogues of the Natural Cyclodepsipeptide Jaspamide 132
Crambines C1 and C2: two further ichthyotoxic guanidine alkaloids from the sponge Crambe crambe 127
Elucidating new structural features of the triazole scaffold for the development of mPGES-1 inhibitors 125
Design,virtual Screening and Synthesis of Potential Microsomal Prostaglandine E2 Synthase-1 (mPGES-1)Inhibitors 122
STARFISH SAPONINS .38. STEROIDAL GLYCOSIDES FROM THE STARFISH PYCNOPODIA-HELIANTHOIDES 120
Isolation and structure of new polyhydroxylated sterols from a deep-water starfish of the genus Rosaster 119
Identification of Honokiol-Based Scaffold to Design Tankyrase 1/2 Inhibitors by In Silico and In Vitro Studies 117
Targeting Microsomal Prostaglanding E2 Synthase 1 for the Development of new potential Anti-Inflammatory Drugs 117
Effects of FR235222, a novel HDAC inhibitor, in proliferation and apoptosis of human leukaemia cell lines: role of annexin A1 117
Discovery of new potent molecular entities able to inhibit mPGES-1 115
Starfish saponins, part 43. Structures of two new sulfated steroidal fucofuranosides (imbricatosides A and B) and six new polyhydroxysteroids from the starfish Dermasterias imbricata 112
Total Synthesis, NMR Solution Structure, and Binding Model of the Potent Histone Deacetylase Inhibitor FR235222 109
Molecular modeling studies toward the structural optimization of new cyclopeptide-based HDAC inhibitors modeled on the natural product FR235222 106
Discovery and synthesis of the first selective BAG domain modulator of BAG3 as an attractive candidate for the development of a new class of chemotherapeutics 106
Identification of 2,4,5-trisubstituted-2,4-dihydro-3H-1,2,4-triazol-3-one-based small molecules as selective BRD9 binders 105
Development of a second generation of inhibitors of microsomal prostaglandin E synthase 1 expression bearing the gamma-hydroxybutenolide scaffold 104
Novel HIV-Inhibitory Halistanol Sulfates F-H from a Marine Sponge, Pseudoaxinissa digitata 104
New Bisindole Alkaloids of the Topsentin and Hamacanthin classes from the Mediterranean marine sponge Rhaphisia lacazei. 104
Edwardsolides A, B and C. New Sesquiterpenoid Lactones from the Mediterranean OctocoralMaasella edwardsi 103
Structure-Based Design of Microsomal Prostaglandin E2 Synthase-1 (mPGES-1) Inhibitors using a Virtual Fragment Growing Optimization Scheme 101
Dactylolide, a New Cytotoxic Macrolide from the Vanuatu Sponge Dactylospongia sp. 100
Synthesis of new mono and bis amides projected as potential histone deacetylase (HDAC) inhibitors 100
Toward the Discovery of New Agents Able to Inhibit the Expression of Microsomal Prostaglandin E Synthase-1 Enzyme as Promising Tools in Drug Development 99
Further brominated bis- and tris-indole alkaloids from the deep water New Caledonian marine sponge Orina sp. 98
Polycyclic guanidine alkaloids from the marine sponge Crambe crambe and calcium channel blocker activity of crambescidin 816 98
Synthetic approach to bioactive marine Cyclopeptide Halipeptin A 98
Synthesis of 2-Amino-8-oxodecanoic Acids (Aodas) Present in Natural Histone Deacetylase Inhibitors. 97
Structure-Based Discovery of Inhibitors of Microsomal Prostaglandin E2 Synthase-1, 5-Lipoxygenase and 5-Lipoxygenase-Activating Protein: Promising Hits for the Development of New Anti-inflammatory Agents 97
Critical Surveys Covering the Year 2004:Total Synthesis of Natural Products 96
Two new guanidine alkaloids from the Mediterranean sponge Crambe crambe 95
Discovery of new molecular entities able to strongly interfere with Hsp90 C-terminal domain 95
A multidisciplinary functional proteomics-aided strategy as a tool for the profiling of a novel cytotoxic thiadiazolopyrimidone 94
Synthesis and Pharmacological Evaluation of a Selected Library of New Potential Anti-Inflammatory Agents Bearing the gamma-hydroxybutenolide Scaffold: a New Class of Inhibitors of Prostanoid Production Through the Selective Modulation of Microsomal prostaglandin E Synthase-1 Expression (mPGES-1). 92
Synthesis, structural aspects and cytotoxicity of the natural cyclopeptides yunnanins A, C and phakellistatins 1, 10 91
Identification by Inverse Virtual Screening of magnolol-based scaffold as new tankyrase-2 inhibitors 91
Marine eicosanoids: occurrence of 8,11,12-trihydroxylated eicosanoic acids in starfishes 90
Glucopyranosylbianthrones from the Algerian Asphodelus tenuifolius: Structural Insights and Biological Evaluation on Melanoma Cancer Cells 89
Synthesis and biological activity of cyclotetrapeptide analogues of the natural HDAC inhibitor FR235222 86
Chemistry and Biology of Chromatin Remodeling Agents: State of Art and Future Perspectives of HDAC Inhibitors 86
Discovery of noscapine derivatives as potential β-tubulin inhibitors 83
Isolation and NMR characterization of rosacelose, a novel sulfated polysaccharide from the sponge Mixylla rosacea. 81
Synthetic and pharmacological studies on new simplified analogues of the potent actin-targeting Jaspamide 79
Dragmacidin F: a New Antiviral Bromo-indole Alkaloid from the Mediterranean Sponge Halicortex sp. 78
Starfish saponins. Part 14. Structures of the steroidal glycoside sufates from the starfish Marthasterias glacialis 77
Exploring the chemical space of functionalized [1,2,4]triazolo[4,3-a]quinoxaline-based compounds targeting the bromodomain of BRD9 77
Synthesis, structure, and biological aspects of cyclopeptides related to marine phakellistatins 7-9 76
Identification of the first-in-class dual inhibitor targeting BAG3 and HSP70 proteins to disrupt multiple chaperone pathways 74
Identification of new γ-hydroxybutenolides that preferentially inhibit the activity of mPGES-1 72
Structural Refinement of 2,4-Thiazolidinedione Derivatives as New Anticancer Agents Able to Modulate the BAG3 Protein 72
Tossine marine: nuove affascinanti molecole bioattive da invertebrati e microrganismi marini. Recenti acquisizioni e prospettive 70
Synthesis, structural aspects and bioactivity of the marine cyclopeptide hymenamide C. 69
Introducing structure-based three-dimensional pharmacophore models for accelerating the discovery of selective BRD9 binders 67
Synthesis, structural aspects and bioactivity of the marine cyclopeptide hymenamide C. 65
Tuning the biomimetic performances of 4-hydroxyproline-containing cyclic peptoids 65
Synthesis And Biological Properties Of The Seven Alanine-Modified Analogues Of The Marine Cyclopeptide Hymenamide C 63
Repositioning of Quinazolinedione-Based Compounds on Soluble Epoxide Hydrolase (sEH) through 3D Structure-Based Pharmacophore Model-Driven Investigation 62
Spongidepsin, a new cytotoxic macrolide from Spongia sp. 60
Synthesis, solution structure, and bioactivity of six new simplified analogues of the natural cyclodepsipeptide jaspamide 60
Regioselective Entry to Bromo-γ -hydroxybutenolides: Useful Building Blocks for Assemblying Natural Product-Like Libraries. 59
Targeting mPGES-1 by a Combinatorial Approach: Identification of the Aminobenzothiazole Scaffold to Suppress PGE2Levels 51
Identification of a New Promising BAG3 Modulator Featuring the Imidazopyridine Scaffold 46
Identification of 2,4-Dinitro-Biphenyl-Based Compounds as MAPEG Inhibitors 39
Identification of 2-Aminoacyl-1,3,4-thiadiazoles as Prostaglandin E2 and Leukotriene Biosynthesis Inhibitors 26
Totale 14.115
Categoria #
all - tutte 38.997
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 38.997


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021475 0 0 0 0 73 36 74 6 111 7 78 90
2021/2022528 4 0 0 14 13 14 12 14 81 68 68 240
2022/20231.000 90 92 22 143 121 192 6 105 131 0 64 34
2023/2024392 37 59 26 16 48 75 19 19 6 15 12 60
2024/20251.172 47 9 7 59 29 112 239 98 184 52 146 190
2025/20266.913 1.690 2.407 2.174 313 329 0 0 0 0 0 0 0
Totale 14.115