BRUNO, Ines
 Distribuzione geografica
Continente #
NA - Nord America 4.248
EU - Europa 1.408
AS - Asia 884
SA - Sud America 132
AF - Africa 8
Continente sconosciuto - Info sul continente non disponibili 6
OC - Oceania 1
Totale 6.687
Nazione #
US - Stati Uniti d'America 4.230
IT - Italia 399
CN - Cina 330
SG - Singapore 313
UA - Ucraina 306
RU - Federazione Russa 222
DE - Germania 147
BR - Brasile 122
IE - Irlanda 109
SE - Svezia 85
TR - Turchia 82
VN - Vietnam 68
FI - Finlandia 63
KR - Corea 45
GB - Regno Unito 22
HK - Hong Kong 17
CZ - Repubblica Ceca 15
CA - Canada 14
IN - India 12
NL - Olanda 12
ES - Italia 6
AT - Austria 5
EU - Europa 5
UZ - Uzbekistan 5
AZ - Azerbaigian 4
FR - Francia 4
AR - Argentina 3
BG - Bulgaria 3
PE - Perù 3
CH - Svizzera 2
DZ - Algeria 2
GT - Guatemala 2
JP - Giappone 2
PK - Pakistan 2
RS - Serbia 2
ZA - Sudafrica 2
A2 - ???statistics.table.value.countryCode.A2??? 1
AE - Emirati Arabi Uniti 1
CO - Colombia 1
EC - Ecuador 1
EG - Egitto 1
HU - Ungheria 1
IL - Israele 1
IQ - Iraq 1
LU - Lussemburgo 1
MA - Marocco 1
MK - Macedonia 1
MX - Messico 1
NG - Nigeria 1
NP - Nepal 1
NZ - Nuova Zelanda 1
PR - Porto Rico 1
PT - Portogallo 1
RO - Romania 1
SC - Seychelles 1
SK - Slovacchia (Repubblica Slovacca) 1
UY - Uruguay 1
VE - Venezuela 1
Totale 6.687
Città #
Ann Arbor 1.074
Woodbridge 439
Chandler 429
Houston 385
Jacksonville 372
Wilmington 324
Princeton 289
Ashburn 125
Singapore 112
Dublin 101
Salerno 101
Izmir 81
Nanjing 78
Andover 67
Dearborn 67
Dong Ket 66
Boardman 64
Pellezzano 54
Beijing 50
Moscow 34
Fairfield 30
Mestre 27
Düsseldorf 25
Redwood City 25
Shenyang 25
Guangzhou 23
Jiaxing 21
Fisciano 20
Hebei 20
Changsha 17
Nanchang 15
Brno 14
Norwalk 14
Acerra 13
Hong Kong 13
Spinea 13
Washington 13
Seattle 12
Pune 10
Tianjin 10
Jinan 9
Naples 9
Dallas 7
Galway 7
Los Angeles 6
Montreal 6
Nuremberg 6
São Paulo 6
Indiana 5
Nürnberg 5
Ottawa 5
Amsterdam 4
Arzano 4
Caianello 4
Chicago 4
Council Bluffs 4
Curitiba 4
Edinburgh 4
London 4
New York 4
Nocera Superiore 4
Pignola 4
Pozzuoli 4
Rome 4
San Francisco 4
Tappahannock 4
Tashkent 4
Wuhan 4
Yubileyny 4
Baku 3
Belo Horizonte 3
Cambridge 3
Campinas 3
Cormano 3
Granada 3
Guarulhos 3
Haikou 3
Jundiaí 3
Messina 3
Napoli 3
Palermo 3
Porto Alegre 3
San Diego 3
Shanghai 3
Sofia 3
Taranto 3
Vienna 3
Apucarana 2
Araraquara 2
Assago 2
Aversa 2
Bari 2
Belgrade 2
Bickley 2
Bonea 2
Buffalo 2
Centro 2
Charlotte 2
Chengdu 2
Clifton 2
Totale 4.895
Nome #
9H-purine scaffold reveals induced-fit pocket plasticity of the BRD9 bromodomain 158
Starfish Saponins, Part 50. Steroidal Glycosides from the Okinawan Starfish Nardoa tuberculata 135
Bioactive Prenylhydroquinone Sulfates and a Novel C31 Furanoterpene Alcohol Sulfate from the Marine Sponge, Ircinia Sp. 132
40 th "A. Corbella" International Summer School on Organic Synthesis - ISOS 2015 127
(±)-Gelliusines A and B, Two Diastereomeric Brominated Tris-indole Alkaloids from a Deep Water New Caledonian Marine Sponge (Gellius or Orina sp.) 125
Makaluvamine P: a New Cytotoxic Pyrroloiminoquinone from Zyzzya cf. fuliginosa 124
Biologically active guanidine alkaloids from the Mediterranean sponge Crambe crambe 120
Targeting the Hsp90 C-terminal domain by the chemically accessible dihydropyrimidinone scaffold 118
Dimeric and trimeric triazole based molecules as a new class of Hsp90 molecular chaperone inhibitors 115
Synthesis, Conformational Analysis, and Cytotoxicity of New Analogues of the Natural Cyclodepsipeptide Jaspamide 113
Anti-inflammatory and analgesic activity of a novel inhibitor of microsomal prostaglandin E synthase-1 expression 112
Design and Synthesis of cyclopeptide analogues of the potent Histone deacetylase inhibitor FR235222 111
Design, Synthesis, and Biological Activity of Hydroxamic Tertiary Amines as Histone Deacetylase Inhibitors 110
Crambines C1 and C2: two further ichthyotoxic guanidine alkaloids from the sponge Crambe crambe 109
Design and synthesis of a second series of triazole-based compounds as potent dual mPGES-1 and 5-lipoxygenase inhibitors 109
STARFISH SAPONINS .38. STEROIDAL GLYCOSIDES FROM THE STARFISH PYCNOPODIA-HELIANTHOIDES 102
Molecular modeling studies toward the structural optimization of new cyclopeptide-based HDAC inhibitors modeled on the natural product FR235222 101
Correction: Identification of the key structural elements of a dihydropyrimidinone core driving toward more potent Hsp90 C-terminal inhibitors 101
New dihydropyrimidin-2(1H)-one based Hsp90 C-terminal inhibitors 100
Isolation and structure of new polyhydroxylated sterols from a deep-water starfish of the genus Rosaster 99
Edwardsolides A, B and C. New Sesquiterpenoid Lactones from the Mediterranean OctocoralMaasella edwardsi 98
Novel HIV-Inhibitory Halistanol Sulfates F-H from a Marine Sponge, Pseudoaxinissa digitata 98
Total Synthesis, NMR Solution Structure, and Binding Model of the Potent Histone Deacetylase Inhibitor FR235222 97
Elucidating new structural features of the triazole scaffold for the development of mPGES-1 inhibitors 97
Bioactive Macrolides and Cylopeptides from South Pacific Sponges 95
Further brominated bis- and tris-indole alkaloids from the deep water New Caledonian marine sponge Orina sp. 94
Exploration of the dihydropyrimidine scaffold for the development of new potential anti-inflammatory agents blocking prostaglandin E2 synthase-1 enzyme (mPGES-1) 94
Design,virtual Screening and Synthesis of Potential Microsomal Prostaglandine E2 Synthase-1 (mPGES-1)Inhibitors 94
Structural Insights for the Optimization of Dihydropyrimidin-2(1H)-one Based mPGES-1 Inhibitors 94
Synthesis of new mono and bis amides projected as potential histone deacetylase (HDAC) inhibitors 93
Targeting Microsomal Prostaglanding E2 Synthase 1 for the Development of new potential Anti-Inflammatory Drugs 93
New Bisindole Alkaloids of the Topsentin and Hamacanthin classes from the Mediterranean marine sponge Rhaphisia lacazei. 93
Toward the Discovery of New Agents Able to Inhibit the Expression of Microsomal Prostaglandin E Synthase-1 Enzyme as Promising Tools in Drug Development 91
Polycyclic guanidine alkaloids from the marine sponge Crambe crambe and calcium channel blocker activity of crambescidin 816 91
Two new guanidine alkaloids from the Mediterranean sponge Crambe crambe 90
Starfish saponins, part 43. Structures of two new sulfated steroidal fucofuranosides (imbricatosides A and B) and six new polyhydroxysteroids from the starfish Dermasterias imbricata 90
Structure-Based Discovery of Inhibitors of Microsomal Prostaglandin E2 Synthase-1, 5-Lipoxygenase and 5-Lipoxygenase-Activating Protein: Promising Hits for the Development of New Anti-inflammatory Agents 89
Synthesis of 2-Amino-8-oxodecanoic Acids (Aodas) Present in Natural Histone Deacetylase Inhibitors. 86
Synthesis and Pharmacological Evaluation of a Selected Library of New Potential Anti-Inflammatory Agents Bearing the gamma-hydroxybutenolide Scaffold: a New Class of Inhibitors of Prostanoid Production Through the Selective Modulation of Microsomal prostaglandin E Synthase-1 Expression (mPGES-1). 85
Structure-Based Design of Microsomal Prostaglandin E2 Synthase-1 (mPGES-1) Inhibitors using a Virtual Fragment Growing Optimization Scheme 84
Dactylolide, a New Cytotoxic Macrolide from the Vanuatu Sponge Dactylospongia sp. 83
Development of a second generation of inhibitors of microsomal prostaglandin E synthase 1 expression bearing the gamma-hydroxybutenolide scaffold 83
Synthesis and biological activity of cyclotetrapeptide analogues of the natural HDAC inhibitor FR235222 81
Synthesis, structural aspects and cytotoxicity of the natural cyclopeptides yunnanins A, C and phakellistatins 1, 10 81
Discovery of new potent molecular entities able to inhibit mPGES-1 81
Marine eicosanoids: occurrence of 8,11,12-trihydroxylated eicosanoic acids in starfishes 80
Synthetic approach to bioactive marine Cyclopeptide Halipeptin A 76
Discovery and synthesis of the first selective BAG domain modulator of BAG3 as an attractive candidate for the development of a new class of chemotherapeutics 76
Structural basis for the design and synthesis of selective HDAC inhibitors 75
Cyclic Peptoids as Mycotoxin Mimics: An Exploration of Their Structural and Biological Properties 74
Identification of the key structural elements of a dihydropyrimidinone core driving toward more potent Hsp90 C-terminal inhibitors 74
A Combinatorial Virtual Screening Approach Driving the Synthesis of 2,4-Thiazolidinedione-Based Molecules as New Dual mPGES-1/5-LO Inhibitors 73
Synthetic and pharmacological studies on new simplified analogues of the potent actin-targeting Jaspamide 72
Synthesis, structure, and biological aspects of cyclopeptides related to marine phakellistatins 7-9 71
Dragmacidin F: a New Antiviral Bromo-indole Alkaloid from the Mediterranean Sponge Halicortex sp. 71
Discovery of new molecular entities able to strongly interfere with Hsp90 C-terminal domain 71
Critical Surveys Covering the Year 2004:Total Synthesis of Natural Products 70
Isolation and NMR characterization of rosacelose, a novel sulfated polysaccharide from the sponge Mixylla rosacea. 68
Starfish saponins. Part 14. Structures of the steroidal glycoside sufates from the starfish Marthasterias glacialis 68
Chemistry and Biology of Chromatin Remodeling Agents: State of Art and Future Perspectives of HDAC Inhibitors 67
Identification of new γ-hydroxybutenolides that preferentially inhibit the activity of mPGES-1 66
Effects of FR235222, a novel HDAC inhibitor, in proliferation and apoptosis of human leukaemia cell lines: role of annexin A1 66
Tossine marine: nuove affascinanti molecole bioattive da invertebrati e microrganismi marini. Recenti acquisizioni e prospettive 65
Synthesis, structural aspects and bioactivity of the marine cyclopeptide hymenamide C. 64
Inhibition of Microsomal Prostaglandin E2 Synthase 1: focused design of new anti-inflammatory and anti-cancer drugs 64
Synthesis, structural aspects and bioactivity of the marine cyclopeptide hymenamide C. 61
Synthesis And Biological Properties Of The Seven Alanine-Modified Analogues Of The Marine Cyclopeptide Hymenamide C 57
Discovery of noscapine derivatives as potential β-tubulin inhibitors 56
Spongidepsin, a new cytotoxic macrolide from Spongia sp. 55
Synthesis, solution structure, and bioactivity of six new simplified analogues of the natural cyclodepsipeptide jaspamide 55
Regioselective Entry to Bromo-γ -hydroxybutenolides: Useful Building Blocks for Assemblying Natural Product-Like Libraries. 54
Identification of 2,4,5-trisubstituted-2,4-dihydro-3H-1,2,4-triazol-3-one-based small molecules as selective BRD9 binders 52
Identification of the 2-Benzoxazol-2-yl-phenol Scaffold as New Hit for JMJD3 Inhibition 51
Tuning the biomimetic performances of 4-hydroxyproline-containing cyclic peptoids 51
Identification by Inverse Virtual Screening of magnolol-based scaffold as new tankyrase-2 inhibitors 50
Structural Refinement of 2,4-Thiazolidinedione Derivatives as New Anticancer Agents Able to Modulate the BAG3 Protein 48
Glucopyranosylbianthrones from the Algerian Asphodelus tenuifolius: Structural Insights and Biological Evaluation on Melanoma Cancer Cells 41
Introducing structure-based three-dimensional pharmacophore models for accelerating the discovery of selective BRD9 binders 39
Repositioning of Quinazolinedione-Based Compounds on Soluble Epoxide Hydrolase (sEH) through 3D Structure-Based Pharmacophore Model-Driven Investigation 38
Targeting mPGES-1 by a Combinatorial Approach: Identification of the Aminobenzothiazole Scaffold to Suppress PGE2Levels 26
From Natural Compounds to Bioactive Molecules through NMR and In Silico Methodologies 24
Identification of 2-(thiophen-2-yl)acetic Acid-Based Lead Compound for mPGES-1 Inhibition 22
Identification of 2,4-Dinitro-Biphenyl-Based Compounds as MAPEG Inhibitors 21
A multidisciplinary functional proteomics-aided strategy as a tool for the profiling of a novel cytotoxic thiadiazolopyrimidone 21
Identification of a New Promising BAG3 Modulator Featuring the Imidazopyridine Scaffold 13
Exploring the chemical space of functionalized [1,2,4]triazolo[4,3-a]quinoxaline-based compounds targeting the bromodomain of BRD9 13
Identification of 2-Aminoacyl-1,3,4-thiadiazoles as Prostaglandin E2 and Leukotriene Biosynthesis Inhibitors 10
Identification of the first-in-class dual inhibitor targeting BAG3 and HSP70 proteins to disrupt multiple chaperone pathways 7
In Silico Design, Chemical Synthesis, Biophysical and in Vitro Evaluation for the Identification of 1-Ethyl-1H-Pyrazolo[3,4-b]Pyridine-Based BRD9 Binders 7
Identification of Novel Bromodomain-Containing Protein 4 (BRD4) Binders through 3D Pharmacophore-Based Repositioning Screening Campaign 6
Identification of Honokiol-Based Scaffold to Design Tankyrase 1/2 Inhibitors by In Silico and In Vitro Studies 5
Totale 6.870
Categoria #
all - tutte 24.895
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 24.895


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020115 0 0 0 0 0 0 0 0 0 0 106 9
2020/2021610 4 61 65 5 73 36 74 6 111 7 78 90
2021/2022528 4 0 0 14 13 14 12 14 81 68 68 240
2022/20231.000 90 92 22 143 121 192 6 105 131 0 64 34
2023/2024392 37 59 26 16 48 75 19 19 6 15 12 60
2024/2025840 47 9 7 59 29 112 239 98 184 52 4 0
Totale 6.870