BRUNO, Ines
 Distribuzione geografica
Continente #
AS - Asia 7.878
NA - Nord America 6.126
EU - Europa 2.304
SA - Sud America 380
Continente sconosciuto - Info sul continente non disponibili 195
AF - Africa 49
OC - Oceania 4
Totale 16.936
Nazione #
US - Stati Uniti d'America 5.995
HK - Hong Kong 5.638
SG - Singapore 969
IT - Italia 922
CN - Cina 563
UA - Ucraina 310
BR - Brasile 279
VN - Vietnam 277
DE - Germania 249
RU - Federazione Russa 228
IE - Irlanda 111
SE - Svezia 101
FR - Francia 96
TR - Turchia 95
FI - Finlandia 88
GB - Regno Unito 76
CA - Canada 71
IN - India 71
KR - Corea 60
AR - Argentina 37
MX - Messico 35
BD - Bangladesh 34
JP - Giappone 34
IQ - Iraq 26
NL - Olanda 23
CZ - Repubblica Ceca 17
ID - Indonesia 17
AT - Austria 16
CO - Colombia 16
ES - Italia 15
PL - Polonia 15
UZ - Uzbekistan 14
ZA - Sudafrica 13
EC - Ecuador 12
PH - Filippine 11
CL - Cile 10
PK - Pakistan 10
VE - Venezuela 9
SA - Arabia Saudita 7
AZ - Azerbaigian 6
CH - Svizzera 6
HU - Ungheria 6
KE - Kenya 6
PE - Perù 6
AE - Emirati Arabi Uniti 5
EG - Egitto 5
EU - Europa 5
GT - Guatemala 5
MA - Marocco 5
NP - Nepal 5
OM - Oman 5
BG - Bulgaria 4
BO - Bolivia 4
CR - Costa Rica 4
JO - Giordania 4
LB - Libano 4
LT - Lituania 4
MY - Malesia 4
NG - Nigeria 4
TN - Tunisia 4
AU - Australia 3
DZ - Algeria 3
IL - Israele 3
JM - Giamaica 3
KZ - Kazakistan 3
PY - Paraguay 3
RO - Romania 3
TH - Thailandia 3
TJ - Tagikistan 3
AL - Albania 2
AO - Angola 2
DO - Repubblica Dominicana 2
ET - Etiopia 2
HN - Honduras 2
NI - Nicaragua 2
PA - Panama 2
PR - Porto Rico 2
PS - Palestinian Territory 2
PT - Portogallo 2
RS - Serbia 2
SK - Slovacchia (Repubblica Slovacca) 2
TT - Trinidad e Tobago 2
UY - Uruguay 2
A2 - ???statistics.table.value.countryCode.A2??? 1
BA - Bosnia-Erzegovina 1
BE - Belgio 1
BH - Bahrain 1
BY - Bielorussia 1
CM - Camerun 1
GA - Gabon 1
GF - Guiana Francese 1
GY - Guiana 1
LA - Repubblica Popolare Democratica del Laos 1
LC - Santa Lucia 1
LU - Lussemburgo 1
MK - Macedonia 1
ML - Mali 1
MN - Mongolia 1
MU - Mauritius 1
NO - Norvegia 1
Totale 16.743
Città #
Hong Kong 5.627
Ann Arbor 1.074
Singapore 545
Woodbridge 439
Chandler 429
San Jose 427
Houston 393
Jacksonville 372
Dallas 330
Wilmington 325
Milan 303
Princeton 289
Ashburn 283
Beijing 132
Salerno 104
Dublin 102
Council Bluffs 98
The Dalles 98
Lauterbourg 83
Izmir 81
Nanjing 79
Rome 75
Munich 70
Andover 67
Dearborn 67
Ho Chi Minh City 67
Dong Ket 66
Boardman 64
New York 56
Pellezzano 54
Hanoi 50
Los Angeles 48
Naples 41
Santa Clara 39
Montreal 38
Moscow 35
Tokyo 34
Orem 32
Fairfield 30
Mestre 27
São Paulo 27
Shenyang 26
Düsseldorf 25
Redwood City 25
Fisciano 24
Figino 23
Guangzhou 23
Frankfurt am Main 22
Turku 22
Jiaxing 21
Memphis 21
Hebei 20
Brooklyn 19
Denver 19
Changsha 18
Stockholm 18
London 17
Boston 16
Chicago 16
Columbus 16
Chennai 15
Mexico City 15
Nanchang 15
San Francisco 15
Turin 15
Warsaw 15
Brno 14
Norwalk 14
Nuremberg 14
Phoenix 14
Washington 14
Acerra 13
Da Nang 13
Spinea 13
Pune 12
Seattle 12
Tashkent 12
Amsterdam 11
Atlanta 11
Johannesburg 11
Charlotte 10
Tianjin 10
Baghdad 9
Jinan 9
Manchester 9
New Delhi 9
Belo Horizonte 8
Curitiba 8
Dhaka 7
Galway 7
Hải Dương 7
Porto Alegre 7
Ankara 6
Haiphong 6
Jakarta 6
Medellín 6
Santiago 6
Shanghai 6
Toronto 6
Wuhan 6
Totale 13.407
Nome #
A Combinatorial Virtual Screening Approach Driving the Synthesis of 2,4-Thiazolidinedione-Based Molecules as New Dual mPGES-1/5-LO Inhibitors 1.132
Inhibition of Microsomal Prostaglandin E2 Synthase 1: focused design of new anti-inflammatory and anti-cancer drugs 946
Identification of 2-(thiophen-2-yl)acetic Acid-Based Lead Compound for mPGES-1 Inhibition 645
Bioactive Prenylhydroquinone Sulfates and a Novel C31 Furanoterpene Alcohol Sulfate from the Marine Sponge, Ircinia Sp. 627
40 th "A. Corbella" International Summer School on Organic Synthesis - ISOS 2015 609
Design, Synthesis, and Biological Activity of Hydroxamic Tertiary Amines as Histone Deacetylase Inhibitors 542
In Silico Design, Chemical Synthesis, Biophysical and in Vitro Evaluation for the Identification of 1-Ethyl-1H-Pyrazolo[3,4-b]Pyridine-Based BRD9 Binders 523
Identification of Novel Bromodomain-Containing Protein 4 (BRD4) Binders through 3D Pharmacophore-Based Repositioning Screening Campaign 404
Identification of the 2-Benzoxazol-2-yl-phenol Scaffold as New Hit for JMJD3 Inhibition 372
9H-purine scaffold reveals induced-fit pocket plasticity of the BRD9 bromodomain 262
Cyclic Peptoids as Mycotoxin Mimics: An Exploration of Their Structural and Biological Properties 214
From Natural Compounds to Bioactive Molecules through NMR and In Silico Methodologies 210
Starfish Saponins, Part 50. Steroidal Glycosides from the Okinawan Starfish Nardoa tuberculata 199
Exploration of the dihydropyrimidine scaffold for the development of new potential anti-inflammatory agents blocking prostaglandin E2 synthase-1 enzyme (mPGES-1) 196
Structural basis for the design and synthesis of selective HDAC inhibitors 195
Targeting the Hsp90 C-terminal domain by the chemically accessible dihydropyrimidinone scaffold 193
Structural Insights for the Optimization of Dihydropyrimidin-2(1H)-one Based mPGES-1 Inhibitors 190
(±)-Gelliusines A and B, Two Diastereomeric Brominated Tris-indole Alkaloids from a Deep Water New Caledonian Marine Sponge (Gellius or Orina sp.) 186
Synthesis, Conformational Analysis, and Cytotoxicity of New Analogues of the Natural Cyclodepsipeptide Jaspamide 181
Makaluvamine P: a New Cytotoxic Pyrroloiminoquinone from Zyzzya cf. fuliginosa 178
Design and synthesis of a second series of triazole-based compounds as potent dual mPGES-1 and 5-lipoxygenase inhibitors 178
Identification of the key structural elements of a dihydropyrimidinone core driving toward more potent Hsp90 C-terminal inhibitors 177
Bioactive Macrolides and Cylopeptides from South Pacific Sponges 175
Dimeric and trimeric triazole based molecules as a new class of Hsp90 molecular chaperone inhibitors 174
Biologically active guanidine alkaloids from the Mediterranean sponge Crambe crambe 172
Design and Synthesis of cyclopeptide analogues of the potent Histone deacetylase inhibitor FR235222 171
Anti-inflammatory and analgesic activity of a novel inhibitor of microsomal prostaglandin E synthase-1 expression 170
Correction: Identification of the key structural elements of a dihydropyrimidinone core driving toward more potent Hsp90 C-terminal inhibitors 168
Design,virtual Screening and Synthesis of Potential Microsomal Prostaglandine E2 Synthase-1 (mPGES-1)Inhibitors 167
New dihydropyrimidin-2(1H)-one based Hsp90 C-terminal inhibitors 165
Identification of 2,4,5-trisubstituted-2,4-dihydro-3H-1,2,4-triazol-3-one-based small molecules as selective BRD9 binders 164
Crambines C1 and C2: two further ichthyotoxic guanidine alkaloids from the sponge Crambe crambe 158
Elucidating new structural features of the triazole scaffold for the development of mPGES-1 inhibitors 156
Effects of FR235222, a novel HDAC inhibitor, in proliferation and apoptosis of human leukaemia cell lines: role of annexin A1 152
Identification of Honokiol-Based Scaffold to Design Tankyrase 1/2 Inhibitors by In Silico and In Vitro Studies 150
Isolation and structure of new polyhydroxylated sterols from a deep-water starfish of the genus Rosaster 147
STARFISH SAPONINS .38. STEROIDAL GLYCOSIDES FROM THE STARFISH PYCNOPODIA-HELIANTHOIDES 145
Targeting Microsomal Prostaglanding E2 Synthase 1 for the Development of new potential Anti-Inflammatory Drugs 145
Discovery of new potent molecular entities able to inhibit mPGES-1 145
Novel HIV-Inhibitory Halistanol Sulfates F-H from a Marine Sponge, Pseudoaxinissa digitata 140
Starfish saponins, part 43. Structures of two new sulfated steroidal fucofuranosides (imbricatosides A and B) and six new polyhydroxysteroids from the starfish Dermasterias imbricata 139
Discovery and synthesis of the first selective BAG domain modulator of BAG3 as an attractive candidate for the development of a new class of chemotherapeutics 137
Total Synthesis, NMR Solution Structure, and Binding Model of the Potent Histone Deacetylase Inhibitor FR235222 134
Structure-Based Design of Microsomal Prostaglandin E2 Synthase-1 (mPGES-1) Inhibitors using a Virtual Fragment Growing Optimization Scheme 134
Dactylolide, a New Cytotoxic Macrolide from the Vanuatu Sponge Dactylospongia sp. 131
Polycyclic guanidine alkaloids from the marine sponge Crambe crambe and calcium channel blocker activity of crambescidin 816 131
Discovery of new molecular entities able to strongly interfere with Hsp90 C-terminal domain 130
Critical Surveys Covering the Year 2004:Total Synthesis of Natural Products 129
Synthesis of new mono and bis amides projected as potential histone deacetylase (HDAC) inhibitors 129
Molecular modeling studies toward the structural optimization of new cyclopeptide-based HDAC inhibitors modeled on the natural product FR235222 128
New Bisindole Alkaloids of the Topsentin and Hamacanthin classes from the Mediterranean marine sponge Rhaphisia lacazei. 127
Development of a second generation of inhibitors of microsomal prostaglandin E synthase 1 expression bearing the gamma-hydroxybutenolide scaffold 126
Edwardsolides A, B and C. New Sesquiterpenoid Lactones from the Mediterranean OctocoralMaasella edwardsi 126
Two new guanidine alkaloids from the Mediterranean sponge Crambe crambe 125
Synthetic approach to bioactive marine Cyclopeptide Halipeptin A 125
Toward the Discovery of New Agents Able to Inhibit the Expression of Microsomal Prostaglandin E Synthase-1 Enzyme as Promising Tools in Drug Development 121
Further brominated bis- and tris-indole alkaloids from the deep water New Caledonian marine sponge Orina sp. 121
Identification by Inverse Virtual Screening of magnolol-based scaffold as new tankyrase-2 inhibitors 120
A multidisciplinary functional proteomics-aided strategy as a tool for the profiling of a novel cytotoxic thiadiazolopyrimidone 120
Identification of the first-in-class dual inhibitor targeting BAG3 and HSP70 proteins to disrupt multiple chaperone pathways 119
Structure-Based Discovery of Inhibitors of Microsomal Prostaglandin E2 Synthase-1, 5-Lipoxygenase and 5-Lipoxygenase-Activating Protein: Promising Hits for the Development of New Anti-inflammatory Agents 119
Synthetic and pharmacological studies on new simplified analogues of the potent actin-targeting Jaspamide 119
Synthesis, structural aspects and cytotoxicity of the natural cyclopeptides yunnanins A, C and phakellistatins 1, 10 119
Synthesis of 2-Amino-8-oxodecanoic Acids (Aodas) Present in Natural Histone Deacetylase Inhibitors. 118
Glucopyranosylbianthrones from the Algerian Asphodelus tenuifolius: Structural Insights and Biological Evaluation on Melanoma Cancer Cells 118
Synthesis and Pharmacological Evaluation of a Selected Library of New Potential Anti-Inflammatory Agents Bearing the gamma-hydroxybutenolide Scaffold: a New Class of Inhibitors of Prostanoid Production Through the Selective Modulation of Microsomal prostaglandin E Synthase-1 Expression (mPGES-1). 117
Chemistry and Biology of Chromatin Remodeling Agents: State of Art and Future Perspectives of HDAC Inhibitors 116
Dragmacidin F: a New Antiviral Bromo-indole Alkaloid from the Mediterranean Sponge Halicortex sp. 108
Structural Refinement of 2,4-Thiazolidinedione Derivatives as New Anticancer Agents Able to Modulate the BAG3 Protein 108
Discovery of noscapine derivatives as potential β-tubulin inhibitors 107
Isolation and NMR characterization of rosacelose, a novel sulfated polysaccharide from the sponge Mixylla rosacea. 106
Synthesis and biological activity of cyclotetrapeptide analogues of the natural HDAC inhibitor FR235222 106
Marine eicosanoids: occurrence of 8,11,12-trihydroxylated eicosanoic acids in starfishes 104
Synthesis, structure, and biological aspects of cyclopeptides related to marine phakellistatins 7-9 101
Identification of new γ-hydroxybutenolides that preferentially inhibit the activity of mPGES-1 99
Exploring the chemical space of functionalized [1,2,4]triazolo[4,3-a]quinoxaline-based compounds targeting the bromodomain of BRD9 99
Repositioning of Quinazolinedione-Based Compounds on Soluble Epoxide Hydrolase (sEH) through 3D Structure-Based Pharmacophore Model-Driven Investigation 97
Starfish saponins. Part 14. Structures of the steroidal glycoside sufates from the starfish Marthasterias glacialis 96
Tossine marine: nuove affascinanti molecole bioattive da invertebrati e microrganismi marini. Recenti acquisizioni e prospettive 95
Tuning the biomimetic performances of 4-hydroxyproline-containing cyclic peptoids 95
Synthesis, structural aspects and bioactivity of the marine cyclopeptide hymenamide C. 93
Introducing structure-based three-dimensional pharmacophore models for accelerating the discovery of selective BRD9 binders 93
Synthesis, structural aspects and bioactivity of the marine cyclopeptide hymenamide C. 88
Synthesis, solution structure, and bioactivity of six new simplified analogues of the natural cyclodepsipeptide jaspamide 86
Synthesis And Biological Properties Of The Seven Alanine-Modified Analogues Of The Marine Cyclopeptide Hymenamide C 84
Spongidepsin, a new cytotoxic macrolide from Spongia sp. 84
Targeting mPGES-1 by a Combinatorial Approach: Identification of the Aminobenzothiazole Scaffold to Suppress PGE2Levels 83
Regioselective Entry to Bromo-γ -hydroxybutenolides: Useful Building Blocks for Assemblying Natural Product-Like Libraries. 75
Identification of 2,4-Dinitro-Biphenyl-Based Compounds as MAPEG Inhibitors 74
Identification of a New Promising BAG3 Modulator Featuring the Imidazopyridine Scaffold 72
Identification of 2-Aminoacyl-1,3,4-thiadiazoles as Prostaglandin E2 and Leukotriene Biosynthesis Inhibitors 54
A Thiadiazolopyrimidinone-Based Molecule Targeting Annexin A6 Impairs Cell Motility and Epithelial-to-Mesenchymal Transition in Pancreatic Cancer Cells Lacking Annexin A1 28
Identification of a New Interesting BAG3 Modulator Able to Disrupt Cancer-Related Pathways 25
Unveiling New Triazoloquinoxaline‐Based PROTACs Designed for the Selective Degradation of the ncBAF Chromatin Remodeling Subunit BRD9 24
Disruption of c-Myc/Max heterodimerization induced by a novel anticancer agent endowed with 1,3-diphenylurea moiety: an in silico, chemoproteomics-based, and in vitro combined approach 20
Carnosol modulates mPGES-1/PPAR-γ biological axis: from in silico to in vivo clinical imaging and investigations 17
From Bench to Bedside: Translational Approaches to Cardiotoxicity in Breast Cancer, Lung Cancer, and Lymphoma Therapies 14
Totale 16.936
Categoria #
all - tutte 46.284
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 46.284


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022524 0 0 0 14 13 14 12 14 81 68 68 240
2022/20231.000 90 92 22 143 121 192 6 105 131 0 64 34
2023/2024392 37 59 26 16 48 75 19 19 6 15 12 60
2024/20251.172 47 9 7 59 29 112 239 98 184 52 146 190
2025/20269.554 1.690 2.407 2.174 313 510 229 645 139 290 499 144 514
2026/2027180 144 36 0 0 0 0 0 0 0 0 0 0
Totale 16.936