BRUNO, Ines
 Distribuzione geografica
Continente #
AS - Asia 7.327
NA - Nord America 5.283
EU - Europa 1.638
SA - Sud America 290
AF - Africa 26
Continente sconosciuto - Info sul continente non disponibili 6
OC - Oceania 4
Totale 14.574
Nazione #
HK - Hong Kong 5.598
US - Stati Uniti d'America 5.203
SG - Singapore 803
CN - Cina 493
IT - Italia 438
UA - Ucraina 306
BR - Brasile 237
RU - Federazione Russa 225
DE - Germania 223
VN - Vietnam 153
IE - Irlanda 110
SE - Svezia 97
TR - Turchia 89
FI - Finlandia 85
GB - Regno Unito 61
CA - Canada 53
KR - Corea 51
IN - India 36
JP - Giappone 27
AR - Argentina 25
MX - Messico 20
CZ - Repubblica Ceca 16
NL - Olanda 16
AT - Austria 13
BD - Bangladesh 13
PL - Polonia 13
IQ - Iraq 12
ID - Indonesia 11
ES - Italia 10
ZA - Sudafrica 10
UZ - Uzbekistan 9
CO - Colombia 6
AZ - Azerbaigian 5
EU - Europa 5
PE - Perù 5
PK - Pakistan 5
AE - Emirati Arabi Uniti 4
BG - Bulgaria 4
EC - Ecuador 4
FR - Francia 4
NG - Nigeria 4
VE - Venezuela 4
AU - Australia 3
CH - Svizzera 3
EG - Egitto 3
GT - Guatemala 3
IL - Israele 3
LT - Lituania 3
MA - Marocco 3
NP - Nepal 3
PY - Paraguay 3
CL - Cile 2
DZ - Algeria 2
KZ - Kazakistan 2
PH - Filippine 2
RO - Romania 2
RS - Serbia 2
SK - Slovacchia (Repubblica Slovacca) 2
TH - Thailandia 2
TJ - Tagikistan 2
UY - Uruguay 2
A2 - ???statistics.table.value.countryCode.A2??? 1
AL - Albania 1
AO - Angola 1
DO - Repubblica Dominicana 1
GF - Guiana Francese 1
GY - Guiana 1
HU - Ungheria 1
KE - Kenya 1
LC - Santa Lucia 1
LU - Lussemburgo 1
MK - Macedonia 1
ML - Mali 1
MY - Malesia 1
NZ - Nuova Zelanda 1
OM - Oman 1
PA - Panama 1
PR - Porto Rico 1
PS - Palestinian Territory 1
PT - Portogallo 1
SC - Seychelles 1
SY - Repubblica araba siriana 1
Totale 14.574
Città #
Hong Kong 5.589
Ann Arbor 1.074
Woodbridge 439
Chandler 429
Singapore 424
Houston 390
Jacksonville 372
Dallas 325
Wilmington 324
Princeton 289
Ashburn 230
San Jose 158
Dublin 101
Salerno 101
Beijing 91
Izmir 81
Nanjing 78
Munich 70
Andover 67
Dearborn 67
Dong Ket 66
Boardman 64
Pellezzano 54
New York 42
The Dalles 36
Moscow 35
Los Angeles 34
Fairfield 30
Montreal 29
Mestre 27
Tokyo 27
Shenyang 26
Düsseldorf 25
Redwood City 25
Naples 24
Guangzhou 23
Ho Chi Minh City 23
São Paulo 22
Turku 22
Fisciano 21
Jiaxing 21
Hebei 20
Orem 20
Brooklyn 18
Changsha 18
Denver 17
Hanoi 17
London 16
Boston 15
Columbus 15
Nanchang 15
Brno 14
Norwalk 14
Stockholm 14
Acerra 13
Chicago 13
Nuremberg 13
San Francisco 13
Santa Clara 13
Spinea 13
Warsaw 13
Washington 13
Pune 12
Seattle 12
Atlanta 10
Johannesburg 10
Tianjin 10
Chennai 9
Jinan 9
Manchester 9
Phoenix 9
Belo Horizonte 8
Charlotte 8
Mexico City 8
Tashkent 8
Curitiba 7
Galway 7
Porto Alegre 7
Rome 7
Ankara 6
Da Nang 6
Wuhan 6
Amsterdam 5
Haiphong 5
Indiana 5
Jakarta 5
Nürnberg 5
Ottawa 5
Arzano 4
Baghdad 4
Baku 4
Caianello 4
Campinas 4
Council Bluffs 4
Des Moines 4
Dhaka 4
Edinburgh 4
Hải Dương 4
Lima 4
New Delhi 4
Totale 11.938
Nome #
A Combinatorial Virtual Screening Approach Driving the Synthesis of 2,4-Thiazolidinedione-Based Molecules as New Dual mPGES-1/5-LO Inhibitors 1.106
Inhibition of Microsomal Prostaglandin E2 Synthase 1: focused design of new anti-inflammatory and anti-cancer drugs 923
Identification of 2-(thiophen-2-yl)acetic Acid-Based Lead Compound for mPGES-1 Inhibition 620
Bioactive Prenylhydroquinone Sulfates and a Novel C31 Furanoterpene Alcohol Sulfate from the Marine Sponge, Ircinia Sp. 606
40 th "A. Corbella" International Summer School on Organic Synthesis - ISOS 2015 574
Design, Synthesis, and Biological Activity of Hydroxamic Tertiary Amines as Histone Deacetylase Inhibitors 515
In Silico Design, Chemical Synthesis, Biophysical and in Vitro Evaluation for the Identification of 1-Ethyl-1H-Pyrazolo[3,4-b]Pyridine-Based BRD9 Binders 507
Identification of Novel Bromodomain-Containing Protein 4 (BRD4) Binders through 3D Pharmacophore-Based Repositioning Screening Campaign 380
Identification of the 2-Benzoxazol-2-yl-phenol Scaffold as New Hit for JMJD3 Inhibition 348
9H-purine scaffold reveals induced-fit pocket plasticity of the BRD9 bromodomain 233
From Natural Compounds to Bioactive Molecules through NMR and In Silico Methodologies 185
Cyclic Peptoids as Mycotoxin Mimics: An Exploration of Their Structural and Biological Properties 185
Starfish Saponins, Part 50. Steroidal Glycosides from the Okinawan Starfish Nardoa tuberculata 177
Structural basis for the design and synthesis of selective HDAC inhibitors 173
Targeting the Hsp90 C-terminal domain by the chemically accessible dihydropyrimidinone scaffold 173
Structural Insights for the Optimization of Dihydropyrimidin-2(1H)-one Based mPGES-1 Inhibitors 170
Exploration of the dihydropyrimidine scaffold for the development of new potential anti-inflammatory agents blocking prostaglandin E2 synthase-1 enzyme (mPGES-1) 168
(±)-Gelliusines A and B, Two Diastereomeric Brominated Tris-indole Alkaloids from a Deep Water New Caledonian Marine Sponge (Gellius or Orina sp.) 164
Dimeric and trimeric triazole based molecules as a new class of Hsp90 molecular chaperone inhibitors 155
Makaluvamine P: a New Cytotoxic Pyrroloiminoquinone from Zyzzya cf. fuliginosa 154
Anti-inflammatory and analgesic activity of a novel inhibitor of microsomal prostaglandin E synthase-1 expression 153
Biologically active guanidine alkaloids from the Mediterranean sponge Crambe crambe 152
Identification of the key structural elements of a dihydropyrimidinone core driving toward more potent Hsp90 C-terminal inhibitors 152
Design and synthesis of a second series of triazole-based compounds as potent dual mPGES-1 and 5-lipoxygenase inhibitors 151
Bioactive Macrolides and Cylopeptides from South Pacific Sponges 146
New dihydropyrimidin-2(1H)-one based Hsp90 C-terminal inhibitors 144
Design and Synthesis of cyclopeptide analogues of the potent Histone deacetylase inhibitor FR235222 141
Correction: Identification of the key structural elements of a dihydropyrimidinone core driving toward more potent Hsp90 C-terminal inhibitors 141
Synthesis, Conformational Analysis, and Cytotoxicity of New Analogues of the Natural Cyclodepsipeptide Jaspamide 140
Crambines C1 and C2: two further ichthyotoxic guanidine alkaloids from the sponge Crambe crambe 135
Design,virtual Screening and Synthesis of Potential Microsomal Prostaglandine E2 Synthase-1 (mPGES-1)Inhibitors 134
Elucidating new structural features of the triazole scaffold for the development of mPGES-1 inhibitors 133
Isolation and structure of new polyhydroxylated sterols from a deep-water starfish of the genus Rosaster 127
STARFISH SAPONINS .38. STEROIDAL GLYCOSIDES FROM THE STARFISH PYCNOPODIA-HELIANTHOIDES 127
Targeting Microsomal Prostaglanding E2 Synthase 1 for the Development of new potential Anti-Inflammatory Drugs 127
Effects of FR235222, a novel HDAC inhibitor, in proliferation and apoptosis of human leukaemia cell lines: role of annexin A1 124
Discovery of new potent molecular entities able to inhibit mPGES-1 123
Identification of Honokiol-Based Scaffold to Design Tankyrase 1/2 Inhibitors by In Silico and In Vitro Studies 121
Starfish saponins, part 43. Structures of two new sulfated steroidal fucofuranosides (imbricatosides A and B) and six new polyhydroxysteroids from the starfish Dermasterias imbricata 120
Identification of 2,4,5-trisubstituted-2,4-dihydro-3H-1,2,4-triazol-3-one-based small molecules as selective BRD9 binders 117
Total Synthesis, NMR Solution Structure, and Binding Model of the Potent Histone Deacetylase Inhibitor FR235222 115
Edwardsolides A, B and C. New Sesquiterpenoid Lactones from the Mediterranean OctocoralMaasella edwardsi 113
Molecular modeling studies toward the structural optimization of new cyclopeptide-based HDAC inhibitors modeled on the natural product FR235222 112
Discovery and synthesis of the first selective BAG domain modulator of BAG3 as an attractive candidate for the development of a new class of chemotherapeutics 112
Novel HIV-Inhibitory Halistanol Sulfates F-H from a Marine Sponge, Pseudoaxinissa digitata 111
Structure-Based Design of Microsomal Prostaglandin E2 Synthase-1 (mPGES-1) Inhibitors using a Virtual Fragment Growing Optimization Scheme 110
Dactylolide, a New Cytotoxic Macrolide from the Vanuatu Sponge Dactylospongia sp. 109
Synthetic approach to bioactive marine Cyclopeptide Halipeptin A 109
Development of a second generation of inhibitors of microsomal prostaglandin E synthase 1 expression bearing the gamma-hydroxybutenolide scaffold 108
Polycyclic guanidine alkaloids from the marine sponge Crambe crambe and calcium channel blocker activity of crambescidin 816 107
New Bisindole Alkaloids of the Topsentin and Hamacanthin classes from the Mediterranean marine sponge Rhaphisia lacazei. 107
Synthesis of new mono and bis amides projected as potential histone deacetylase (HDAC) inhibitors 106
Discovery of new molecular entities able to strongly interfere with Hsp90 C-terminal domain 106
Toward the Discovery of New Agents Able to Inhibit the Expression of Microsomal Prostaglandin E Synthase-1 Enzyme as Promising Tools in Drug Development 104
Two new guanidine alkaloids from the Mediterranean sponge Crambe crambe 104
A multidisciplinary functional proteomics-aided strategy as a tool for the profiling of a novel cytotoxic thiadiazolopyrimidone 104
Further brominated bis- and tris-indole alkaloids from the deep water New Caledonian marine sponge Orina sp. 103
Critical Surveys Covering the Year 2004:Total Synthesis of Natural Products 102
Synthesis of 2-Amino-8-oxodecanoic Acids (Aodas) Present in Natural Histone Deacetylase Inhibitors. 101
Structure-Based Discovery of Inhibitors of Microsomal Prostaglandin E2 Synthase-1, 5-Lipoxygenase and 5-Lipoxygenase-Activating Protein: Promising Hits for the Development of New Anti-inflammatory Agents 100
Synthesis, structural aspects and cytotoxicity of the natural cyclopeptides yunnanins A, C and phakellistatins 1, 10 99
Synthesis and Pharmacological Evaluation of a Selected Library of New Potential Anti-Inflammatory Agents Bearing the gamma-hydroxybutenolide Scaffold: a New Class of Inhibitors of Prostanoid Production Through the Selective Modulation of Microsomal prostaglandin E Synthase-1 Expression (mPGES-1). 96
Glucopyranosylbianthrones from the Algerian Asphodelus tenuifolius: Structural Insights and Biological Evaluation on Melanoma Cancer Cells 96
Identification by Inverse Virtual Screening of magnolol-based scaffold as new tankyrase-2 inhibitors 96
Marine eicosanoids: occurrence of 8,11,12-trihydroxylated eicosanoic acids in starfishes 95
Chemistry and Biology of Chromatin Remodeling Agents: State of Art and Future Perspectives of HDAC Inhibitors 94
Synthesis and biological activity of cyclotetrapeptide analogues of the natural HDAC inhibitor FR235222 92
Discovery of noscapine derivatives as potential β-tubulin inhibitors 87
Isolation and NMR characterization of rosacelose, a novel sulfated polysaccharide from the sponge Mixylla rosacea. 86
Identification of the first-in-class dual inhibitor targeting BAG3 and HSP70 proteins to disrupt multiple chaperone pathways 84
Synthetic and pharmacological studies on new simplified analogues of the potent actin-targeting Jaspamide 84
Dragmacidin F: a New Antiviral Bromo-indole Alkaloid from the Mediterranean Sponge Halicortex sp. 83
Starfish saponins. Part 14. Structures of the steroidal glycoside sufates from the starfish Marthasterias glacialis 82
Synthesis, structure, and biological aspects of cyclopeptides related to marine phakellistatins 7-9 81
Structural Refinement of 2,4-Thiazolidinedione Derivatives as New Anticancer Agents Able to Modulate the BAG3 Protein 79
Exploring the chemical space of functionalized [1,2,4]triazolo[4,3-a]quinoxaline-based compounds targeting the bromodomain of BRD9 79
Tossine marine: nuove affascinanti molecole bioattive da invertebrati e microrganismi marini. Recenti acquisizioni e prospettive 78
Identification of new γ-hydroxybutenolides that preferentially inhibit the activity of mPGES-1 78
Synthesis, structural aspects and bioactivity of the marine cyclopeptide hymenamide C. 77
Synthesis, structural aspects and bioactivity of the marine cyclopeptide hymenamide C. 72
Tuning the biomimetic performances of 4-hydroxyproline-containing cyclic peptoids 72
Repositioning of Quinazolinedione-Based Compounds on Soluble Epoxide Hydrolase (sEH) through 3D Structure-Based Pharmacophore Model-Driven Investigation 71
Introducing structure-based three-dimensional pharmacophore models for accelerating the discovery of selective BRD9 binders 71
Synthesis And Biological Properties Of The Seven Alanine-Modified Analogues Of The Marine Cyclopeptide Hymenamide C 70
Synthesis, solution structure, and bioactivity of six new simplified analogues of the natural cyclodepsipeptide jaspamide 66
Spongidepsin, a new cytotoxic macrolide from Spongia sp. 65
Regioselective Entry to Bromo-γ -hydroxybutenolides: Useful Building Blocks for Assemblying Natural Product-Like Libraries. 65
Targeting mPGES-1 by a Combinatorial Approach: Identification of the Aminobenzothiazole Scaffold to Suppress PGE2Levels 61
Identification of a New Promising BAG3 Modulator Featuring the Imidazopyridine Scaffold 52
Identification of 2,4-Dinitro-Biphenyl-Based Compounds as MAPEG Inhibitors 49
Identification of 2-Aminoacyl-1,3,4-thiadiazoles as Prostaglandin E2 and Leukotriene Biosynthesis Inhibitors 30
Totale 14.757
Categoria #
all - tutte 40.455
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 40.455


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021366 0 0 0 0 0 0 74 6 111 7 78 90
2021/2022528 4 0 0 14 13 14 12 14 81 68 68 240
2022/20231.000 90 92 22 143 121 192 6 105 131 0 64 34
2023/2024392 37 59 26 16 48 75 19 19 6 15 12 60
2024/20251.172 47 9 7 59 29 112 239 98 184 52 146 190
2025/20267.555 1.690 2.407 2.174 313 510 229 232 0 0 0 0 0
Totale 14.757