BRUNO, Ines
 Distribuzione geografica
Continente #
AS - Asia 7.885
NA - Nord America 6.805
EU - Europa 2.325
SA - Sud America 387
Continente sconosciuto - Info sul continente non disponibili 195
AF - Africa 49
OC - Oceania 4
Totale 17.650
Nazione #
US - Stati Uniti d'America 6.642
HK - Hong Kong 5.639
SG - Singapore 969
IT - Italia 933
CN - Cina 566
UA - Ucraina 310
BR - Brasile 285
VN - Vietnam 277
DE - Germania 249
RU - Federazione Russa 228
IE - Irlanda 111
SE - Svezia 101
FR - Francia 96
CA - Canada 95
TR - Turchia 95
FI - Finlandia 88
GB - Regno Unito 81
IN - India 72
KR - Corea 60
AR - Argentina 37
BD - Bangladesh 35
MX - Messico 35
JP - Giappone 34
IQ - Iraq 26
NL - Olanda 23
CO - Colombia 17
CZ - Repubblica Ceca 17
ID - Indonesia 17
PL - Polonia 17
AT - Austria 16
ES - Italia 16
UZ - Uzbekistan 14
ZA - Sudafrica 13
EC - Ecuador 12
PH - Filippine 12
CL - Cile 10
PK - Pakistan 10
VE - Venezuela 9
CH - Svizzera 8
SA - Arabia Saudita 7
AZ - Azerbaigian 6
HU - Ungheria 6
KE - Kenya 6
PE - Perù 6
AE - Emirati Arabi Uniti 5
CR - Costa Rica 5
EG - Egitto 5
EU - Europa 5
GT - Guatemala 5
MA - Marocco 5
NP - Nepal 5
OM - Oman 5
BG - Bulgaria 4
BO - Bolivia 4
JM - Giamaica 4
JO - Giordania 4
LB - Libano 4
LT - Lituania 4
MY - Malesia 4
NG - Nigeria 4
NI - Nicaragua 4
TN - Tunisia 4
AU - Australia 3
DZ - Algeria 3
HN - Honduras 3
IL - Israele 3
KZ - Kazakistan 3
PY - Paraguay 3
RO - Romania 3
TH - Thailandia 3
TJ - Tagikistan 3
TT - Trinidad e Tobago 3
AL - Albania 2
AO - Angola 2
DO - Repubblica Dominicana 2
ET - Etiopia 2
PA - Panama 2
PR - Porto Rico 2
PS - Palestinian Territory 2
PT - Portogallo 2
RS - Serbia 2
SK - Slovacchia (Repubblica Slovacca) 2
UY - Uruguay 2
A2 - ???statistics.table.value.countryCode.A2??? 1
BA - Bosnia-Erzegovina 1
BE - Belgio 1
BH - Bahrain 1
BY - Bielorussia 1
BZ - Belize 1
CM - Camerun 1
GA - Gabon 1
GF - Guiana Francese 1
GY - Guiana 1
LA - Repubblica Popolare Democratica del Laos 1
LC - Santa Lucia 1
LU - Lussemburgo 1
MK - Macedonia 1
ML - Mali 1
MN - Mongolia 1
MU - Mauritius 1
Totale 17.455
Città #
Hong Kong 5.628
Ann Arbor 1.074
San Jose 552
Singapore 545
Woodbridge 439
Chandler 429
Houston 397
Jacksonville 372
Ashburn 362
Dallas 336
Wilmington 325
Milan 305
Princeton 289
Council Bluffs 190
Beijing 135
Salerno 104
Dublin 102
The Dalles 98
Lauterbourg 83
New York 82
Izmir 81
Nanjing 79
Rome 75
Munich 70
Andover 67
Dearborn 67
Ho Chi Minh City 67
Dong Ket 66
Boardman 64
Los Angeles 62
Pellezzano 54
Hanoi 50
Santa Clara 45
Naples 44
Montreal 41
Moscow 35
Tokyo 34
Orem 33
São Paulo 32
Fairfield 30
Phoenix 28
Mestre 27
Shenyang 26
Düsseldorf 25
Redwood City 25
Fisciano 24
Figino 23
Guangzhou 23
Brooklyn 22
Frankfurt am Main 22
Turku 22
Jiaxing 21
Memphis 21
Chicago 20
Denver 20
Hebei 20
Changsha 18
Stockholm 18
Boston 17
London 17
San Francisco 17
Warsaw 17
Atlanta 16
Columbus 16
Norwalk 16
Turin 16
Chennai 15
Mexico City 15
Nanchang 15
Washington 15
Brno 14
Nuremberg 14
Acerra 13
Da Nang 13
Seattle 13
Spinea 13
Pune 12
Tashkent 12
Amsterdam 11
Johannesburg 11
Philadelphia 11
Toronto 11
Charlotte 10
Tianjin 10
Baghdad 9
Jinan 9
Manchester 9
New Delhi 9
Belo Horizonte 8
Curitiba 8
Dhaka 7
Galway 7
Hải Dương 7
Newark 7
Porto Alegre 7
Ankara 6
Haiphong 6
Jakarta 6
Medellín 6
Ottawa 6
Totale 13.825
Nome #
A Combinatorial Virtual Screening Approach Driving the Synthesis of 2,4-Thiazolidinedione-Based Molecules as New Dual mPGES-1/5-LO Inhibitors 1.141
Inhibition of Microsomal Prostaglandin E2 Synthase 1: focused design of new anti-inflammatory and anti-cancer drugs 964
Identification of 2-(thiophen-2-yl)acetic Acid-Based Lead Compound for mPGES-1 Inhibition 650
Bioactive Prenylhydroquinone Sulfates and a Novel C31 Furanoterpene Alcohol Sulfate from the Marine Sponge, Ircinia Sp. 632
40 th "A. Corbella" International Summer School on Organic Synthesis - ISOS 2015 618
Design, Synthesis, and Biological Activity of Hydroxamic Tertiary Amines as Histone Deacetylase Inhibitors 552
In Silico Design, Chemical Synthesis, Biophysical and in Vitro Evaluation for the Identification of 1-Ethyl-1H-Pyrazolo[3,4-b]Pyridine-Based BRD9 Binders 538
Identification of Novel Bromodomain-Containing Protein 4 (BRD4) Binders through 3D Pharmacophore-Based Repositioning Screening Campaign 410
Identification of the 2-Benzoxazol-2-yl-phenol Scaffold as New Hit for JMJD3 Inhibition 378
9H-purine scaffold reveals induced-fit pocket plasticity of the BRD9 bromodomain 272
From Natural Compounds to Bioactive Molecules through NMR and In Silico Methodologies 224
Cyclic Peptoids as Mycotoxin Mimics: An Exploration of Their Structural and Biological Properties 224
Starfish Saponins, Part 50. Steroidal Glycosides from the Okinawan Starfish Nardoa tuberculata 203
Exploration of the dihydropyrimidine scaffold for the development of new potential anti-inflammatory agents blocking prostaglandin E2 synthase-1 enzyme (mPGES-1) 201
Structural basis for the design and synthesis of selective HDAC inhibitors 200
Synthesis, Conformational Analysis, and Cytotoxicity of New Analogues of the Natural Cyclodepsipeptide Jaspamide 197
Targeting the Hsp90 C-terminal domain by the chemically accessible dihydropyrimidinone scaffold 197
Structural Insights for the Optimization of Dihydropyrimidin-2(1H)-one Based mPGES-1 Inhibitors 196
(±)-Gelliusines A and B, Two Diastereomeric Brominated Tris-indole Alkaloids from a Deep Water New Caledonian Marine Sponge (Gellius or Orina sp.) 191
Bioactive Macrolides and Cylopeptides from South Pacific Sponges 190
Design and synthesis of a second series of triazole-based compounds as potent dual mPGES-1 and 5-lipoxygenase inhibitors 185
Identification of the key structural elements of a dihydropyrimidinone core driving toward more potent Hsp90 C-terminal inhibitors 183
Makaluvamine P: a New Cytotoxic Pyrroloiminoquinone from Zyzzya cf. fuliginosa 182
Biologically active guanidine alkaloids from the Mediterranean sponge Crambe crambe 180
Dimeric and trimeric triazole based molecules as a new class of Hsp90 molecular chaperone inhibitors 179
Design and Synthesis of cyclopeptide analogues of the potent Histone deacetylase inhibitor FR235222 176
Anti-inflammatory and analgesic activity of a novel inhibitor of microsomal prostaglandin E synthase-1 expression 176
Correction: Identification of the key structural elements of a dihydropyrimidinone core driving toward more potent Hsp90 C-terminal inhibitors 173
New dihydropyrimidin-2(1H)-one based Hsp90 C-terminal inhibitors 172
Identification of 2,4,5-trisubstituted-2,4-dihydro-3H-1,2,4-triazol-3-one-based small molecules as selective BRD9 binders 171
Design,virtual Screening and Synthesis of Potential Microsomal Prostaglandine E2 Synthase-1 (mPGES-1)Inhibitors 171
Targeting Microsomal Prostaglanding E2 Synthase 1 for the Development of new potential Anti-Inflammatory Drugs 168
Crambines C1 and C2: two further ichthyotoxic guanidine alkaloids from the sponge Crambe crambe 165
Elucidating new structural features of the triazole scaffold for the development of mPGES-1 inhibitors 161
Effects of FR235222, a novel HDAC inhibitor, in proliferation and apoptosis of human leukaemia cell lines: role of annexin A1 161
Identification of Honokiol-Based Scaffold to Design Tankyrase 1/2 Inhibitors by In Silico and In Vitro Studies 155
STARFISH SAPONINS .38. STEROIDAL GLYCOSIDES FROM THE STARFISH PYCNOPODIA-HELIANTHOIDES 152
Isolation and structure of new polyhydroxylated sterols from a deep-water starfish of the genus Rosaster 151
Discovery of new potent molecular entities able to inhibit mPGES-1 151
Novel HIV-Inhibitory Halistanol Sulfates F-H from a Marine Sponge, Pseudoaxinissa digitata 146
Discovery and synthesis of the first selective BAG domain modulator of BAG3 as an attractive candidate for the development of a new class of chemotherapeutics 145
Total Synthesis, NMR Solution Structure, and Binding Model of the Potent Histone Deacetylase Inhibitor FR235222 144
Starfish saponins, part 43. Structures of two new sulfated steroidal fucofuranosides (imbricatosides A and B) and six new polyhydroxysteroids from the starfish Dermasterias imbricata 143
Structure-Based Design of Microsomal Prostaglandin E2 Synthase-1 (mPGES-1) Inhibitors using a Virtual Fragment Growing Optimization Scheme 140
New Bisindole Alkaloids of the Topsentin and Hamacanthin classes from the Mediterranean marine sponge Rhaphisia lacazei. 139
Synthetic approach to bioactive marine Cyclopeptide Halipeptin A 136
Dactylolide, a New Cytotoxic Macrolide from the Vanuatu Sponge Dactylospongia sp. 135
Synthesis of new mono and bis amides projected as potential histone deacetylase (HDAC) inhibitors 135
Discovery of new molecular entities able to strongly interfere with Hsp90 C-terminal domain 135
Polycyclic guanidine alkaloids from the marine sponge Crambe crambe and calcium channel blocker activity of crambescidin 816 134
Critical Surveys Covering the Year 2004:Total Synthesis of Natural Products 133
Molecular modeling studies toward the structural optimization of new cyclopeptide-based HDAC inhibitors modeled on the natural product FR235222 133
Edwardsolides A, B and C. New Sesquiterpenoid Lactones from the Mediterranean OctocoralMaasella edwardsi 131
Development of a second generation of inhibitors of microsomal prostaglandin E synthase 1 expression bearing the gamma-hydroxybutenolide scaffold 130
Two new guanidine alkaloids from the Mediterranean sponge Crambe crambe 130
Synthesis of 2-Amino-8-oxodecanoic Acids (Aodas) Present in Natural Histone Deacetylase Inhibitors. 128
Synthesis, structural aspects and cytotoxicity of the natural cyclopeptides yunnanins A, C and phakellistatins 1, 10 128
A multidisciplinary functional proteomics-aided strategy as a tool for the profiling of a novel cytotoxic thiadiazolopyrimidone 127
Toward the Discovery of New Agents Able to Inhibit the Expression of Microsomal Prostaglandin E Synthase-1 Enzyme as Promising Tools in Drug Development 126
Further brominated bis- and tris-indole alkaloids from the deep water New Caledonian marine sponge Orina sp. 126
Identification by Inverse Virtual Screening of magnolol-based scaffold as new tankyrase-2 inhibitors 126
Identification of the first-in-class dual inhibitor targeting BAG3 and HSP70 proteins to disrupt multiple chaperone pathways 125
Structure-Based Discovery of Inhibitors of Microsomal Prostaglandin E2 Synthase-1, 5-Lipoxygenase and 5-Lipoxygenase-Activating Protein: Promising Hits for the Development of New Anti-inflammatory Agents 125
Glucopyranosylbianthrones from the Algerian Asphodelus tenuifolius: Structural Insights and Biological Evaluation on Melanoma Cancer Cells 125
Synthetic and pharmacological studies on new simplified analogues of the potent actin-targeting Jaspamide 124
Chemistry and Biology of Chromatin Remodeling Agents: State of Art and Future Perspectives of HDAC Inhibitors 122
Synthesis and Pharmacological Evaluation of a Selected Library of New Potential Anti-Inflammatory Agents Bearing the gamma-hydroxybutenolide Scaffold: a New Class of Inhibitors of Prostanoid Production Through the Selective Modulation of Microsomal prostaglandin E Synthase-1 Expression (mPGES-1). 121
Dragmacidin F: a New Antiviral Bromo-indole Alkaloid from the Mediterranean Sponge Halicortex sp. 115
Isolation and NMR characterization of rosacelose, a novel sulfated polysaccharide from the sponge Mixylla rosacea. 113
Synthesis and biological activity of cyclotetrapeptide analogues of the natural HDAC inhibitor FR235222 112
Discovery of noscapine derivatives as potential β-tubulin inhibitors 112
Structural Refinement of 2,4-Thiazolidinedione Derivatives as New Anticancer Agents Able to Modulate the BAG3 Protein 112
Marine eicosanoids: occurrence of 8,11,12-trihydroxylated eicosanoic acids in starfishes 110
Starfish saponins. Part 14. Structures of the steroidal glycoside sufates from the starfish Marthasterias glacialis 110
Tossine marine: nuove affascinanti molecole bioattive da invertebrati e microrganismi marini. Recenti acquisizioni e prospettive 107
Synthesis, structure, and biological aspects of cyclopeptides related to marine phakellistatins 7-9 106
Repositioning of Quinazolinedione-Based Compounds on Soluble Epoxide Hydrolase (sEH) through 3D Structure-Based Pharmacophore Model-Driven Investigation 104
Identification of new γ-hydroxybutenolides that preferentially inhibit the activity of mPGES-1 104
Exploring the chemical space of functionalized [1,2,4]triazolo[4,3-a]quinoxaline-based compounds targeting the bromodomain of BRD9 104
Introducing structure-based three-dimensional pharmacophore models for accelerating the discovery of selective BRD9 binders 103
Tuning the biomimetic performances of 4-hydroxyproline-containing cyclic peptoids 102
Synthesis, structural aspects and bioactivity of the marine cyclopeptide hymenamide C. 96
Targeting mPGES-1 by a Combinatorial Approach: Identification of the Aminobenzothiazole Scaffold to Suppress PGE2Levels 96
Spongidepsin, a new cytotoxic macrolide from Spongia sp. 91
Synthesis, structural aspects and bioactivity of the marine cyclopeptide hymenamide C. 91
Synthesis, solution structure, and bioactivity of six new simplified analogues of the natural cyclodepsipeptide jaspamide 91
Synthesis And Biological Properties Of The Seven Alanine-Modified Analogues Of The Marine Cyclopeptide Hymenamide C 89
Regioselective Entry to Bromo-γ -hydroxybutenolides: Useful Building Blocks for Assemblying Natural Product-Like Libraries. 86
Identification of a New Promising BAG3 Modulator Featuring the Imidazopyridine Scaffold 81
Identification of 2,4-Dinitro-Biphenyl-Based Compounds as MAPEG Inhibitors 80
Identification of 2-Aminoacyl-1,3,4-thiadiazoles as Prostaglandin E2 and Leukotriene Biosynthesis Inhibitors 61
Disruption of c-Myc/Max heterodimerization induced by a novel anticancer agent endowed with 1,3-diphenylurea moiety: an in silico, chemoproteomics-based, and in vitro combined approach 40
A Thiadiazolopyrimidinone-Based Molecule Targeting Annexin A6 Impairs Cell Motility and Epithelial-to-Mesenchymal Transition in Pancreatic Cancer Cells Lacking Annexin A1 36
Unveiling New Triazoloquinoxaline‐Based PROTACs Designed for the Selective Degradation of the ncBAF Chromatin Remodeling Subunit BRD9 35
Identification of a New Interesting BAG3 Modulator Able to Disrupt Cancer-Related Pathways 33
From Bench to Bedside: Translational Approaches to Cardiotoxicity in Breast Cancer, Lung Cancer, and Lymphoma Therapies 25
Carnosol modulates mPGES-1/PPAR-γ biological axis: from in silico to in vivo clinical imaging and investigations 23
Totale 17.650
Categoria #
all - tutte 48.823
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 48.823


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022524 0 0 0 14 13 14 12 14 81 68 68 240
2022/20231.000 90 92 22 143 121 192 6 105 131 0 64 34
2023/2024392 37 59 26 16 48 75 19 19 6 15 12 60
2024/20251.172 47 9 7 59 29 112 239 98 184 52 146 190
2025/20269.554 1.690 2.407 2.174 313 510 229 645 139 290 499 144 514
2026/2027894 144 150 331 269 0 0 0 0 0 0 0 0
Totale 17.650