BRUNO, Ines
 Distribuzione geografica
Continente #
AS - Asia 7.793
NA - Nord America 5.810
EU - Europa 1.827
SA - Sud America 373
AF - Africa 49
Continente sconosciuto - Info sul continente non disponibili 6
OC - Oceania 4
Totale 15.862
Nazione #
US - Stati Uniti d'America 5.710
HK - Hong Kong 5.619
SG - Singapore 948
CN - Cina 526
IT - Italia 456
UA - Ucraina 310
VN - Vietnam 276
BR - Brasile 275
DE - Germania 249
RU - Federazione Russa 228
IE - Irlanda 111
SE - Svezia 101
TR - Turchia 95
FR - Francia 93
FI - Finlandia 88
GB - Regno Unito 75
IN - India 71
KR - Corea 60
CA - Canada 58
AR - Argentina 37
JP - Giappone 34
MX - Messico 29
BD - Bangladesh 27
IQ - Iraq 26
NL - Olanda 22
CZ - Repubblica Ceca 17
ID - Indonesia 17
AT - Austria 16
CO - Colombia 15
PL - Polonia 15
UZ - Uzbekistan 14
ES - Italia 13
ZA - Sudafrica 13
EC - Ecuador 12
PH - Filippine 11
PK - Pakistan 10
VE - Venezuela 9
CL - Cile 8
SA - Arabia Saudita 7
AZ - Azerbaigian 6
HU - Ungheria 6
KE - Kenya 6
PE - Perù 6
AE - Emirati Arabi Uniti 5
CH - Svizzera 5
EG - Egitto 5
EU - Europa 5
MA - Marocco 5
NP - Nepal 5
OM - Oman 5
BG - Bulgaria 4
BO - Bolivia 4
JO - Giordania 4
LB - Libano 4
MY - Malesia 4
NG - Nigeria 4
TN - Tunisia 4
AU - Australia 3
DZ - Algeria 3
GT - Guatemala 3
IL - Israele 3
KZ - Kazakistan 3
LT - Lituania 3
PY - Paraguay 3
RO - Romania 3
TH - Thailandia 3
TJ - Tagikistan 3
AL - Albania 2
AO - Angola 2
DO - Repubblica Dominicana 2
ET - Etiopia 2
NI - Nicaragua 2
PA - Panama 2
PS - Palestinian Territory 2
PT - Portogallo 2
RS - Serbia 2
SK - Slovacchia (Repubblica Slovacca) 2
UY - Uruguay 2
A2 - ???statistics.table.value.countryCode.A2??? 1
BE - Belgio 1
BH - Bahrain 1
CM - Camerun 1
CR - Costa Rica 1
GA - Gabon 1
GF - Guiana Francese 1
GY - Guiana 1
HN - Honduras 1
LA - Repubblica Popolare Democratica del Laos 1
LC - Santa Lucia 1
LU - Lussemburgo 1
MK - Macedonia 1
ML - Mali 1
MN - Mongolia 1
MU - Mauritius 1
NO - Norvegia 1
NZ - Nuova Zelanda 1
PR - Porto Rico 1
QA - Qatar 1
SC - Seychelles 1
SY - Repubblica araba siriana 1
Totale 15.862
Città #
Hong Kong 5.610
Ann Arbor 1.074
Singapore 530
Woodbridge 439
Chandler 429
Houston 391
San Jose 374
Jacksonville 372
Dallas 328
Wilmington 324
Princeton 289
Ashburn 271
Beijing 102
Dublin 102
Salerno 101
Council Bluffs 98
The Dalles 98
Lauterbourg 83
Izmir 81
Nanjing 79
Munich 70
Andover 67
Dearborn 67
Ho Chi Minh City 67
Dong Ket 66
Boardman 64
Pellezzano 54
Hanoi 50
New York 50
Los Angeles 38
Moscow 35
Tokyo 34
Montreal 33
Orem 32
Fairfield 30
Naples 28
Santa Clara 28
Mestre 27
Shenyang 26
São Paulo 26
Düsseldorf 25
Redwood City 25
Fisciano 24
Guangzhou 23
Frankfurt am Main 22
Turku 22
Jiaxing 21
Hebei 20
Brooklyn 19
Changsha 18
Denver 18
Stockholm 18
London 16
Boston 15
Chennai 15
Chicago 15
Columbus 15
Nanchang 15
Warsaw 15
Brno 14
Norwalk 14
Nuremberg 14
Acerra 13
Da Nang 13
San Francisco 13
Spinea 13
Washington 13
Pune 12
Seattle 12
Tashkent 12
Amsterdam 11
Johannesburg 11
Mexico City 11
Phoenix 11
Atlanta 10
Tianjin 10
Baghdad 9
Charlotte 9
Jinan 9
Manchester 9
New Delhi 9
Belo Horizonte 8
Curitiba 8
Dhaka 7
Galway 7
Hải Dương 7
Porto Alegre 7
Rome 7
Ankara 6
Jakarta 6
Medellín 6
Wuhan 6
Baku 5
Biên Hòa 5
City of London 5
Des Moines 5
Haiphong 5
Indiana 5
Istanbul 5
Lima 5
Totale 12.795
Nome #
A Combinatorial Virtual Screening Approach Driving the Synthesis of 2,4-Thiazolidinedione-Based Molecules as New Dual mPGES-1/5-LO Inhibitors 1.126
Inhibition of Microsomal Prostaglandin E2 Synthase 1: focused design of new anti-inflammatory and anti-cancer drugs 941
Identification of 2-(thiophen-2-yl)acetic Acid-Based Lead Compound for mPGES-1 Inhibition 642
Bioactive Prenylhydroquinone Sulfates and a Novel C31 Furanoterpene Alcohol Sulfate from the Marine Sponge, Ircinia Sp. 621
40 th "A. Corbella" International Summer School on Organic Synthesis - ISOS 2015 594
Design, Synthesis, and Biological Activity of Hydroxamic Tertiary Amines as Histone Deacetylase Inhibitors 532
In Silico Design, Chemical Synthesis, Biophysical and in Vitro Evaluation for the Identification of 1-Ethyl-1H-Pyrazolo[3,4-b]Pyridine-Based BRD9 Binders 521
Identification of Novel Bromodomain-Containing Protein 4 (BRD4) Binders through 3D Pharmacophore-Based Repositioning Screening Campaign 393
Identification of the 2-Benzoxazol-2-yl-phenol Scaffold as New Hit for JMJD3 Inhibition 362
9H-purine scaffold reveals induced-fit pocket plasticity of the BRD9 bromodomain 247
Cyclic Peptoids as Mycotoxin Mimics: An Exploration of Their Structural and Biological Properties 204
From Natural Compounds to Bioactive Molecules through NMR and In Silico Methodologies 200
Starfish Saponins, Part 50. Steroidal Glycosides from the Okinawan Starfish Nardoa tuberculata 190
Targeting the Hsp90 C-terminal domain by the chemically accessible dihydropyrimidinone scaffold 188
Structural basis for the design and synthesis of selective HDAC inhibitors 187
Structural Insights for the Optimization of Dihydropyrimidin-2(1H)-one Based mPGES-1 Inhibitors 183
(±)-Gelliusines A and B, Two Diastereomeric Brominated Tris-indole Alkaloids from a Deep Water New Caledonian Marine Sponge (Gellius or Orina sp.) 181
Exploration of the dihydropyrimidine scaffold for the development of new potential anti-inflammatory agents blocking prostaglandin E2 synthase-1 enzyme (mPGES-1) 181
Synthesis, Conformational Analysis, and Cytotoxicity of New Analogues of the Natural Cyclodepsipeptide Jaspamide 172
Design and synthesis of a second series of triazole-based compounds as potent dual mPGES-1 and 5-lipoxygenase inhibitors 169
Biologically active guanidine alkaloids from the Mediterranean sponge Crambe crambe 168
Identification of the key structural elements of a dihydropyrimidinone core driving toward more potent Hsp90 C-terminal inhibitors 168
Makaluvamine P: a New Cytotoxic Pyrroloiminoquinone from Zyzzya cf. fuliginosa 166
Anti-inflammatory and analgesic activity of a novel inhibitor of microsomal prostaglandin E synthase-1 expression 165
Dimeric and trimeric triazole based molecules as a new class of Hsp90 molecular chaperone inhibitors 162
Bioactive Macrolides and Cylopeptides from South Pacific Sponges 162
Design and Synthesis of cyclopeptide analogues of the potent Histone deacetylase inhibitor FR235222 160
New dihydropyrimidin-2(1H)-one based Hsp90 C-terminal inhibitors 156
Correction: Identification of the key structural elements of a dihydropyrimidinone core driving toward more potent Hsp90 C-terminal inhibitors 156
Crambines C1 and C2: two further ichthyotoxic guanidine alkaloids from the sponge Crambe crambe 154
Design,virtual Screening and Synthesis of Potential Microsomal Prostaglandine E2 Synthase-1 (mPGES-1)Inhibitors 154
Elucidating new structural features of the triazole scaffold for the development of mPGES-1 inhibitors 143
Identification of 2,4,5-trisubstituted-2,4-dihydro-3H-1,2,4-triazol-3-one-based small molecules as selective BRD9 binders 142
STARFISH SAPONINS .38. STEROIDAL GLYCOSIDES FROM THE STARFISH PYCNOPODIA-HELIANTHOIDES 141
Targeting Microsomal Prostaglanding E2 Synthase 1 for the Development of new potential Anti-Inflammatory Drugs 141
Discovery of new potent molecular entities able to inhibit mPGES-1 141
Isolation and structure of new polyhydroxylated sterols from a deep-water starfish of the genus Rosaster 139
Effects of FR235222, a novel HDAC inhibitor, in proliferation and apoptosis of human leukaemia cell lines: role of annexin A1 139
Identification of Honokiol-Based Scaffold to Design Tankyrase 1/2 Inhibitors by In Silico and In Vitro Studies 138
Starfish saponins, part 43. Structures of two new sulfated steroidal fucofuranosides (imbricatosides A and B) and six new polyhydroxysteroids from the starfish Dermasterias imbricata 132
Discovery and synthesis of the first selective BAG domain modulator of BAG3 as an attractive candidate for the development of a new class of chemotherapeutics 131
Structure-Based Design of Microsomal Prostaglandin E2 Synthase-1 (mPGES-1) Inhibitors using a Virtual Fragment Growing Optimization Scheme 126
Novel HIV-Inhibitory Halistanol Sulfates F-H from a Marine Sponge, Pseudoaxinissa digitata 125
Total Synthesis, NMR Solution Structure, and Binding Model of the Potent Histone Deacetylase Inhibitor FR235222 122
Synthesis of new mono and bis amides projected as potential histone deacetylase (HDAC) inhibitors 122
Discovery of new molecular entities able to strongly interfere with Hsp90 C-terminal domain 122
Dactylolide, a New Cytotoxic Macrolide from the Vanuatu Sponge Dactylospongia sp. 121
Critical Surveys Covering the Year 2004:Total Synthesis of Natural Products 120
Edwardsolides A, B and C. New Sesquiterpenoid Lactones from the Mediterranean OctocoralMaasella edwardsi 120
Synthetic approach to bioactive marine Cyclopeptide Halipeptin A 120
Molecular modeling studies toward the structural optimization of new cyclopeptide-based HDAC inhibitors modeled on the natural product FR235222 119
Polycyclic guanidine alkaloids from the marine sponge Crambe crambe and calcium channel blocker activity of crambescidin 816 119
New Bisindole Alkaloids of the Topsentin and Hamacanthin classes from the Mediterranean marine sponge Rhaphisia lacazei. 119
Development of a second generation of inhibitors of microsomal prostaglandin E synthase 1 expression bearing the gamma-hydroxybutenolide scaffold 117
Further brominated bis- and tris-indole alkaloids from the deep water New Caledonian marine sponge Orina sp. 116
Toward the Discovery of New Agents Able to Inhibit the Expression of Microsomal Prostaglandin E Synthase-1 Enzyme as Promising Tools in Drug Development 115
A multidisciplinary functional proteomics-aided strategy as a tool for the profiling of a novel cytotoxic thiadiazolopyrimidone 114
Two new guanidine alkaloids from the Mediterranean sponge Crambe crambe 113
Synthesis, structural aspects and cytotoxicity of the natural cyclopeptides yunnanins A, C and phakellistatins 1, 10 112
Identification by Inverse Virtual Screening of magnolol-based scaffold as new tankyrase-2 inhibitors 112
Synthetic and pharmacological studies on new simplified analogues of the potent actin-targeting Jaspamide 111
Structure-Based Discovery of Inhibitors of Microsomal Prostaglandin E2 Synthase-1, 5-Lipoxygenase and 5-Lipoxygenase-Activating Protein: Promising Hits for the Development of New Anti-inflammatory Agents 110
Chemistry and Biology of Chromatin Remodeling Agents: State of Art and Future Perspectives of HDAC Inhibitors 110
Synthesis of 2-Amino-8-oxodecanoic Acids (Aodas) Present in Natural Histone Deacetylase Inhibitors. 107
Synthesis and Pharmacological Evaluation of a Selected Library of New Potential Anti-Inflammatory Agents Bearing the gamma-hydroxybutenolide Scaffold: a New Class of Inhibitors of Prostanoid Production Through the Selective Modulation of Microsomal prostaglandin E Synthase-1 Expression (mPGES-1). 107
Glucopyranosylbianthrones from the Algerian Asphodelus tenuifolius: Structural Insights and Biological Evaluation on Melanoma Cancer Cells 107
Discovery of noscapine derivatives as potential β-tubulin inhibitors 103
Synthesis and biological activity of cyclotetrapeptide analogues of the natural HDAC inhibitor FR235222 102
Marine eicosanoids: occurrence of 8,11,12-trihydroxylated eicosanoic acids in starfishes 102
Identification of the first-in-class dual inhibitor targeting BAG3 and HSP70 proteins to disrupt multiple chaperone pathways 101
Structural Refinement of 2,4-Thiazolidinedione Derivatives as New Anticancer Agents Able to Modulate the BAG3 Protein 98
Dragmacidin F: a New Antiviral Bromo-indole Alkaloid from the Mediterranean Sponge Halicortex sp. 97
Isolation and NMR characterization of rosacelose, a novel sulfated polysaccharide from the sponge Mixylla rosacea. 92
Repositioning of Quinazolinedione-Based Compounds on Soluble Epoxide Hydrolase (sEH) through 3D Structure-Based Pharmacophore Model-Driven Investigation 91
Identification of new γ-hydroxybutenolides that preferentially inhibit the activity of mPGES-1 91
Exploring the chemical space of functionalized [1,2,4]triazolo[4,3-a]quinoxaline-based compounds targeting the bromodomain of BRD9 91
Tossine marine: nuove affascinanti molecole bioattive da invertebrati e microrganismi marini. Recenti acquisizioni e prospettive 89
Synthesis, structure, and biological aspects of cyclopeptides related to marine phakellistatins 7-9 88
Starfish saponins. Part 14. Structures of the steroidal glycoside sufates from the starfish Marthasterias glacialis 88
Synthesis, structural aspects and bioactivity of the marine cyclopeptide hymenamide C. 85
Synthesis, structural aspects and bioactivity of the marine cyclopeptide hymenamide C. 84
Introducing structure-based three-dimensional pharmacophore models for accelerating the discovery of selective BRD9 binders 83
Tuning the biomimetic performances of 4-hydroxyproline-containing cyclic peptoids 82
Synthesis, solution structure, and bioactivity of six new simplified analogues of the natural cyclodepsipeptide jaspamide 80
Synthesis And Biological Properties Of The Seven Alanine-Modified Analogues Of The Marine Cyclopeptide Hymenamide C 78
Targeting mPGES-1 by a Combinatorial Approach: Identification of the Aminobenzothiazole Scaffold to Suppress PGE2Levels 76
Spongidepsin, a new cytotoxic macrolide from Spongia sp. 70
Regioselective Entry to Bromo-γ -hydroxybutenolides: Useful Building Blocks for Assemblying Natural Product-Like Libraries. 69
Identification of a New Promising BAG3 Modulator Featuring the Imidazopyridine Scaffold 65
Identification of 2,4-Dinitro-Biphenyl-Based Compounds as MAPEG Inhibitors 65
Identification of 2-Aminoacyl-1,3,4-thiadiazoles as Prostaglandin E2 and Leukotriene Biosynthesis Inhibitors 44
A Thiadiazolopyrimidinone-Based Molecule Targeting Annexin A6 Impairs Cell Motility and Epithelial-to-Mesenchymal Transition in Pancreatic Cancer Cells Lacking Annexin A1 17
Identification of a New Interesting BAG3 Modulator Able to Disrupt Cancer-Related Pathways 11
Disruption of c-Myc/Max heterodimerization induced by a novel anticancer agent endowed with 1,3-diphenylurea moiety: an in silico, chemoproteomics-based, and in vitro combined approach 7
From Bench to Bedside: Translational Approaches to Cardiotoxicity in Breast Cancer, Lung Cancer, and Lymphoma Therapies 2
Carnosol modulates mPGES-1/PPAR-γ biological axis: from in silico to in vivo clinical imaging and investigations 1
Unveiling New Triazoloquinoxaline‐Based PROTACs Designed for the Selective Degradation of the ncBAF Chromatin Remodeling Subunit BRD9 1
Totale 16.051
Categoria #
all - tutte 42.419
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 42.419


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021175 0 0 0 0 0 0 0 0 0 7 78 90
2021/2022528 4 0 0 14 13 14 12 14 81 68 68 240
2022/20231.000 90 92 22 143 121 192 6 105 131 0 64 34
2023/2024392 37 59 26 16 48 75 19 19 6 15 12 60
2024/20251.172 47 9 7 59 29 112 239 98 184 52 146 190
2025/20268.849 1.690 2.407 2.174 313 510 229 645 139 290 452 0 0
Totale 16.051